The Role of Endothelial Dysfunction and Inflammation in Chronic Venous Disease.
暂无分享,去创建一个
[1] S. Hahn,et al. Recommendations for the medical management of chronic venous disease: The role of Micronized Purified Flavanoid Fraction (MPFF) , 2017, Phlebology.
[2] A. Puca,et al. Rac1 Pharmacological Inhibition Rescues Human Endothelial Dysfunction , 2017, Journal of the American Heart Association.
[3] K. Książek,et al. Endovenous Laser Ablation of Varicose Veins Preserves Biological Properties of Vascular Endothelium and Modulates Proinflammatory Agent Profile More Favorably Than Classic Vein Stripping , 2017, BioMed research international.
[4] J. Raffetto,et al. Chronic venous disease - Part I: Inflammatory biomarkers in wound healing. , 2016, Biochimica et biophysica acta.
[5] P. Secchiero,et al. Oscillatory flow suppression improves inflammation in chronic venous disease. , 2016, The Journal of surgical research.
[6] S. Desai,et al. The Impact of Race on Advanced Chronic Venous Insufficiency. , 2016, Annals of vascular surgery.
[7] J. Tarbell,et al. The glycocalyx and its significance in human medicine , 2016, Journal of internal medicine.
[8] G. Geroulakos,et al. Endogenous pro-thrombotic biomarkers from the arm and leg may not have the same value , 2016, Phlebology.
[9] G. Geroulakos,et al. Are Inflammatory Biomarkers Increased in Varicose Vein Blood? , 2016, Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis.
[10] R. Khalil,et al. Matrix Metalloproteinases as Regulators of Vein Structure and Function: Implications in Chronic Venous Disease , 2015, The Journal of Pharmacology and Experimental Therapeutics.
[11] M. Kucharzewski,et al. Effect of Micronized Purified Flavonoid Fraction Therapy on Endothelin-1 and TNF-α Levels in Relation to Antioxidant Enzyme Balance in the Peripheral Blood of Women with Varicose Veins. , 2015, Current vascular pharmacology.
[12] J. Fareed,et al. Do blood constituents in varicose veins differ from the systemic blood constituents? , 2015, European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery.
[13] T. Urbanek,et al. Sulodexide suppresses inflammation in patients with chronic venous insufficiency. , 2015, International angiology : a journal of the International Union of Angiology.
[14] F. Ponziani,et al. Biomarkers of low-grade inflammation in primary varicose veins of the lower limbs. , 2015, European review for medical and pharmacological sciences.
[15] G. Geroulakos,et al. d-Dimer Levels are Significantly Increased in Blood Taken From Varicose Veins Compared With Antecubital Blood From the Same Patient , 2015, Angiology.
[16] G. Schmid-Schönbein,et al. Cellular and molecular basis of Venous insufficiency , 2014, Vascular cell.
[17] R. Launois,et al. Linguistic validation of the 20 item-chronic venous disease quality-of-life questionnaire (CIVIQ-20) , 2014, Phlebology.
[18] J. Raffetto,et al. Glycosaminoglycan sulodexide modulates inflammatory pathways in chronic venous disease. , 2014, International angiology : a journal of the International Union of Angiology.
[19] R. Kirsner,et al. Elevated Levels of Coagulation Factor VIII in Patients With Venous Leg Ulcers , 2014, The international journal of lower extremity wounds.
[20] Hong Zhang,et al. RETRACTED ARTICLE: Molecular basis underlying inhibition of metastasis of gastric cancer by anti-VEGFa treatment , 2014, Tumor Biology.
[21] K. Kohama,et al. Platelet-derived growth factor-BB induces matrix metalloproteinase-2 expression and rat vascular smooth muscle cell migration via ROCK and ERK/p38 MAPK pathways , 2014, Molecular and Cellular Biochemistry.
[22] E. Zubkova,et al. Urokinase Stimulates Production of Matrix Metalloproteinase-9 in Fibroblasts with Involvement of Reactive Oxygen Species , 2014, Bulletin of Experimental Biology and Medicine.
[23] J. Raffetto,et al. Pathophysiology of chronic venous disease. , 2014, International angiology : a journal of the International Union of Angiology.
[24] A. Munari,et al. [Medical significance of endothelial glycocalyx. Part 2: Its role in vascular diseases and in diabetic complications]. , 2014, Archivos de cardiologia de Mexico.
[25] P. Secchiero,et al. Modulation of Circulating Cytokine-Chemokine Profile in Patients Affected by Chronic Venous Insufficiency Undergoing Surgical Hemodynamic Correction , 2014, Journal of immunology research.
[26] M. Hecker,et al. Pathogenesis of varicose veins - lessons from biomechanics. , 2014, VASA. Zeitschrift fur Gefasskrankheiten.
[27] N. Uriel,et al. Peripheral venous congestion causes inflammation, neurohormonal, and endothelial cell activation. , 2014, European heart journal.
[28] D. Longrois,et al. Decreased PGE2 Content Reduces MMP-1 Activity and Consequently Increases Collagen Density in Human Varicose Vein , 2014, PloS one.
[29] D. Agrawal,et al. MMP‐1 and MMP‐9 regulate epidermal growth factor‐dependent collagen loss in human carotid plaque smooth muscle cells , 2014, Physiological reports.
[30] A. Frati-Munari,et al. [Medical significance of endothelial glycocalyx]. , 2013, Archivos de cardiologia de Mexico.
[31] J. Raffetto,et al. Glycosaminoglycan sulodexide inhibition of MMP-9 gelatinase secretion and activity: possible pharmacological role against collagen degradation in vascular chronic diseases. , 2013, Current vascular pharmacology.
[32] R. Khalil,et al. Matrix metalloproteinases as potential targets in the venous dilation associated with varicose veins. , 2013, Current drug targets.
[33] J. Raffetto. Inflammation in chronic venous ulcers , 2013, Phlebology.
[34] Jennifer H. Shin,et al. Heparan Sulfate Regrowth Profiles Under Laminar Shear Flow Following Enzymatic Degradation , 2013, Cellular and molecular bioengineering.
[35] Lena Blomgren,et al. Parameter der Koagulation und Fibrinolyse bei Patienten mit chronischer venöser Insuffizienz , 2013 .
[36] G. Gambaro,et al. A new mechanism of action of sulodexide in diabetic nephropathy: inhibits heparanase-1 and prevents FGF-2-induced renal epithelial-mesenchymal transition , 2012, Journal of Translational Medicine.
[37] J. Szecsenyi,et al. Varicose veins are a risk factor for deep venous thrombosis in general practice patients. , 2012, VASA. Zeitschrift fur Gefasskrankheiten.
[38] R. Launois,et al. Construction and international validation of CIVIQ-14 (a short form of CIVIQ-20), a new questionnaire with a stable factorial structure , 2012, Quality of Life Research.
[39] J. Shalhoub,et al. The Effect of Pressure-Induced Mechanical Stretch on Vascular Wall Differential Gene Expression , 2012, Journal of Vascular Research.
[40] P. Secchiero,et al. Endothelial Cells Obtained from Patients Affected by Chronic Venous Disease Exhibit a Pro-Inflammatory Phenotype , 2012, PloS one.
[41] A. Davies,et al. Increased activation of the hypoxia-inducible factor pathway in varicose veins. , 2012, Journal of vascular surgery.
[42] H. Atta. Varicose Veins: Role of Mechanotransduction of Venous Hypertension , 2012, International journal of vascular medicine.
[43] D. Laukens,et al. Oral supplementation with sulodexide inhibits neo-angiogenesis in a rat model of peritoneal perfusion. , 2012, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.
[44] H. Lipowsky. The Endothelial Glycocalyx as a Barrier to Leukocyte Adhesion and Its Mediation by Extracellular Proteases , 2011, Annals of Biomedical Engineering.
[45] M. Hecker,et al. Experimental hypertension triggers varicosis‐like maladaptive venous remodeling through activator protein‐1 , 2011, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[46] A. Połubińska,et al. Sulodexide reduces senescence-related changes in human endothelial cells , 2011, Medical science monitor : international medical journal of experimental and clinical research.
[47] S. Lehoux,et al. Characterization of the Differential Response of Endothelial Cells Exposed to Normal and Elevated Laminar Shear Stress , 2011, Journal of cellular physiology.
[48] H. H. Lipowsky,et al. Composition of the endothelial glycocalyx and its relation to its thickness and diffusion of small solutes. , 2010, Microvascular research.
[49] M. Ma,et al. Mechanosensitive transient receptor potential vanilloid type 1 channels contribute to vascular remodeling of rat fistula veins. , 2010, Journal of vascular surgery.
[50] P. Delafontaine,et al. Interleukin-18 induces EMMPRIN expression in primary cardiomyocytes via JNK/Sp1 signaling and MMP-9 in part via EMMPRIN and through AP-1 and NF-kappaB activation. , 2010, American journal of physiology. Heart and circulatory physiology.
[51] J. Raffetto,et al. MMP-2 induced vein relaxation via inhibition of [Ca2+]e-dependent mechanisms of venous smooth muscle contraction. Role of RGD peptides. , 2010, The Journal of surgical research.
[52] A. Davies,et al. Prolonged mechanical stretch is associated with upregulation of hypoxia-inducible factors and reduced contraction in rat inferior vena cava. , 2010, Journal of vascular surgery.
[53] M. Myśliwiec,et al. Effect of Sulodexide on Plasma Transforming Growth Factor-β1 in Healthy Volunteers , 2010, Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis.
[54] G. Nash,et al. A role for the endothelial glycosaminoglycan hyaluronan in neutrophil recruitment by endothelial cells cultured for prolonged periods , 2009, Experimental cell research.
[55] A. Davies,et al. Pathogenesis of primary varicose veins , 2009, The British journal of surgery.
[56] Ying Lin,et al. In vitro differences between smooth muscle cells derived from varicose veins and normal veins. , 2009, Journal of vascular surgery.
[57] A. Mulivor,et al. Inhibition of Glycan Shedding and Leukocyte‐Endothelial Adhesion in Postcapillary Venules by Suppression of Matrixmetalloprotease Activity with Doxycycline , 2009, Microcirculation.
[58] H. Ogawa,et al. Significance of a multiple biomarkers strategy including endothelial dysfunction to improve risk stratification for cardiovascular events in patients at high risk for coronary heart disease. , 2009, Journal of the American College of Cardiology.
[59] W. Marston,et al. Inflammatory cytokine levels in chronic venous insufficiency ulcer tissue before and after compression therapy. , 2009, Journal of vascular surgery.
[60] A. Połubińska,et al. Sulodexide suppresses inflammation in human endothelial cells and prevents glucose cytotoxicity. , 2009, Translational research : the journal of laboratory and clinical medicine.
[61] H. Vidrio,et al. Endothelial Function Impairment in Chronic Venous Insufficiency: Effect of Some Cardiovascular Protectant Agents , 2009, Angiology.
[62] J. Tarlton,et al. The relationship between cytokine concentrations and wound healing in chronic venous ulceration. , 2008, Journal of vascular surgery.
[63] J. Raffetto,et al. Prolonged increases in vein wall tension increase matrix metalloproteinases and decrease constriction in rat vena cava: Potential implications in varicose veins. , 2008, Journal of vascular surgery.
[64] Young-Chae Chang,et al. Tanshinone IIA from Salvia miltiorrhiza BUNGE inhibits human aortic smooth muscle cell migration and MMP‐9 activity through AKT signaling pathway , 2008, Journal of cellular biochemistry.
[65] J. Raffetto,et al. Mechanisms of varicose vein formation: valve dysfunction and wall dilation , 2008, Phlebology.
[66] K. C. Overman,et al. Mitogen-Activated Protein Kinase p38 Pathway in Venous Ulcer Fibroblasts , 2008, Vascular and endovascular surgery.
[67] J. Tekoppele,et al. Effect of collagen turnover and matrix metalloproteinase activity on healing of venous leg ulcers , 2008, The British journal of surgery.
[68] J. Raffetto,et al. Matrix metalloproteinases and their inhibitors in vascular remodeling and vascular disease. , 2008, Biochemical pharmacology.
[69] A. Połubińska,et al. Anti-Inflammatory Effect of Sulodexide during Acute Peritonitis in Rats , 2008, Blood Purification.
[70] J. Naoum,et al. Pathogenesis of Varicose Veins and Implications for Clinical Management , 2007, Vascular.
[71] P. Wiedemann,et al. Positive feedback regulation between MMP-9 and VEGF in human RPE cells. , 2007, Investigative ophthalmology & visual science.
[72] A. Lescanic,et al. Shedding of the Endothelial Glycocalyx in Arterioles, Capillaries and Venules , 2007, American journal of physiology. Heart and circulatory physiology.
[73] G. Pascual,et al. TGF-β1 Upregulation in the Aging Varicose Vein , 2007, Journal of Vascular Research.
[74] J. Raffetto,et al. Matrix metalloproteinase 2-induced venous dilation via hyperpolarization and activation of K+ channels: relevance to varicose vein formation. , 2007, Journal of vascular surgery.
[75] G. Godeau,et al. Comparison of extracellular matrix in skin and saphenous veins from patients with varicose veins: does the skin reflect venous matrix changes? , 2007, Clinical science.
[76] M. Knaapen,et al. The Histopathology of Varicose Vein Disease , 2006, Angiology.
[77] G. Schmid-Schönbein,et al. Chronic venous disease. , 2006, The New England journal of medicine.
[78] J. Constans,et al. Circulating markers of endothelial function in cardiovascular disease. , 2006, Clinica chimica acta; international journal of clinical chemistry.
[79] Gloria Avalos,et al. The impact of differential expression of extracellular matrix metalloproteinase inducer, matrix metalloproteinase-2, tissue inhibitor of matrix metalloproteinase-2 and PDGF-AA on the chronicity of venous leg ulcers. , 2006, European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery.
[80] G. Belcaro,et al. Circulating Endothelial Cells in Venous Blood as a Marker of Endothelial Damage in Chronic Venous Insufficiency: Improvement with Venoruton , 2006, Journal of cardiovascular pharmacology and therapeutics.
[81] J. Raffetto,et al. Mitogen-Activated Protein Kinase Pathway Regulates Cell Proliferation in Venous Ulcer Fibroblasts , 2006, Vascular and endovascular surgery.
[82] J. Fabiani,et al. Decreased Production of Collagen Type III in Cultured Smooth Muscle Cells from Varicose Vein Patients Is due to a Degradation by MMPs: Possible Implication of MMP-3 , 2005, Journal of Vascular Research.
[83] J. Beebe-Dimmer,et al. The epidemiology of chronic venous insufficiency and varicose veins. , 2005, Annals of epidemiology.
[84] T. Jacob,et al. Overexpression of transforming growth factor-beta1 correlates with increased synthesis of nitric oxide synthase in varicose veins. , 2005, Journal of Vascular Surgery.
[85] R. Khalil,et al. Matrix metalloproteinase-specific inhibition of Ca2+ entry mechanisms of vascular contraction. , 2004, Journal of vascular surgery.
[86] G. Schmid-Schönbein,et al. Venous hypertension, inflammation and valve remodeling. , 2004, European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery.
[87] P. Ganz,et al. Role of Endothelial Dysfunction in Atherosclerosis , 2004, Circulation.
[88] A. Mulivor,et al. Inflammation- and ischemia-induced shedding of venular glycocalyx. , 2004, American journal of physiology. Heart and circulatory physiology.
[89] O. Topolcan,et al. Bioimpedance Analysis and Assessment of Intracellular Water in Peritoneal Dialysis Patients , 2003, Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis.
[90] S. Verma,et al. New Markers of Inflammation and Endothelial Cell Activation: Part I , 2003, Circulation.
[91] M. Stacey,et al. Cytokines and growth factors in keratinocytes and sweat glands in chronic venous leg ulcers. An immunohistochemical study , 2003, Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society.
[92] J. Spaan,et al. Endothelial Cell Glycocalyx Modulates Immobilization of Leukocytes at the Endothelial Surface , 2003, Arteriosclerosis, thrombosis, and vascular biology.
[93] G. Hunter,et al. Morphologic characteristics of varicose veins: possible role of metalloproteinases. , 2003, Journal of vascular surgery.
[94] Amir Lerman,et al. Endothelial Dysfunction: A Marker of Atherosclerotic Risk , 2003, Arteriosclerosis, thrombosis, and vascular biology.
[95] M. Idzko,et al. Elevated expression of extracellular matrix metalloproteinase inducer (CD147) and membrane‐type matrix metalloproteinases in venous leg ulcers , 2002, The British journal of dermatology.
[96] A. Mulivor,et al. Role of glycocalyx in leukocyte-endothelial cell adhesion. , 2002, American journal of physiology. Heart and circulatory physiology.
[97] N. Rich,et al. Varicose veins possess greater quantities of MMP-1 than normal veins and demonstrate regional variation in MMP-1 and MMP-13. , 2002, The Journal of surgical research.
[98] J. Michel,et al. Plasma Matrix Metalloproteinase-9 as a Marker of Blood Stasis in Varicose Veins , 2002, Circulation.
[99] J. Fabiani,et al. Synthesis of Collagen Is Dysregulated in Cultured Fibroblasts Derived From Skin of Subjects With Varicose Veins as It Is in Venous Smooth Muscle Cells , 2002, Circulation.
[100] Cynthia Cohen,et al. Reactive oxygen generated by Nox1 triggers the angiogenic switch , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[101] M. Stacey,et al. Mitogenic activity and cytokine levels in non‐healing and healing chronic leg ulcers , 2001, Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society.
[102] J. Fabiani,et al. Imbalance in the Synthesis of Collagen Type I and Collagen Type III in Smooth Muscle Cells Derived from Human Varicose Veins , 2001, Journal of Vascular Research.
[103] A. Siegbahn,et al. Coagulation and fibrinolysis in chronic venous insufficiency. , 2001, VASA. Zeitschrift fur Gefasskrankheiten.
[104] J. Michel,et al. Smooth muscle cell modulation and cytokine overproduction in varicose veins. An in situ study , 2001, The Journal of pathology.
[105] B. Duling,et al. TNF-α increases entry of macromolecules into luminal endothelial cell glycocalyx , 2000 .
[106] A. Nicolaides,et al. Investigation of chronic venous insufficiency: A consensus statement (France, March 5-9, 1997). , 2000, Circulation.
[107] J. Norgauer,et al. Plasminogen activation in venous leg ulcers , 2000, The British journal of dermatology.
[108] F. Dignat-George,et al. Circulating endothelial cells in vascular disorders: new insights into an old concept , 2000, European journal of haematology.
[109] M. Jacob,et al. Increased TIMP/MMP ratio in varicose veins: a possible explanation for extracellular matrix accumulation , 2000, The Journal of pathology.
[110] G. Schmid-Schönbein,et al. Expression of Adhesion Molecules and Cytokines on Saphenous Veins in Chronic Venous Insufficiency , 2000, Annals of vascular surgery.
[111] W. Wahl,et al. Changes in the extracellular matrix of the vein wall--the cause of primary varicosis? , 2000 .
[112] A. Morla,et al. Control of smooth muscle cell proliferation and phenotype by integrin signaling through focal adhesion kinase. , 2000, Biochemical and biophysical research communications.
[113] P. Weismann,et al. The determination of the collagen and elastin amount in the human varicose vein by the computer morphometric method. , 1999, General physiology and biophysics.
[114] P. Smith. Neutrophil Activation and Mediators of Inflammation in Chronic Venous Insufficiency , 1999, Journal of Vascular Research.
[115] G. Schmid-Schönbein,et al. Leukocyte activation in patients with venous insufficiency. , 1999, Journal of vascular surgery.
[116] M. Knaapen,et al. Vascular Remodeling in Varicose Veins , 1998, Angiology.
[117] W. Giannobile,et al. Tetracyclines Inhibit Connective Tissue Breakdown by Multiple Non-Antimicrobial Mechanisms , 1998, Advances in dental research.
[118] P. Coleridge-Smith,et al. Increased plasma vascular endothelial growth factor among patients with chronic venous disease. , 1998, Journal of vascular surgery.
[119] J. Scurr,et al. Leukocyte activity in the microcirculation of the leg in patients with chronic venous disease. , 1997, Journal of vascular surgery.
[120] R. Launois,et al. Construction and validation of a quality of life questionnaire in Chronic Lower Limb Venous Insufficiency (CIVIQ) , 1996, Quality of Life Research.
[121] H. Sato,et al. v-Src activates the expression of 92-kDa type IV collagenase gene through the AP-1 site and the GT box homologous to retinoblastoma control elements. A mechanism regulating gene expression independent of that by inflammatory cytokines. , 1993, The Journal of biological chemistry.
[122] M. D. Tilson,et al. Analysis of the connective tissue matrix and proteolytic activity of primary varicose veins. , 1993, Journal of vascular surgery.
[123] A. Nicolaides,et al. Venous wall function in the pathogenesis of varicose veins. , 1992, Surgery.
[124] J. Raffetto,et al. Sulodexide down-regulates the release of cytokines, chemokines, and leukocyte colony stimulating factors from human macrophages: role of glycosaminoglycans in inflammatory pathways of chronic venous disease. , 2014, Current vascular pharmacology.
[125] J. Tarbell,et al. Interstitial flow induces MMP-1 expression and vascular SMC migration in collagen I gels via an ERK1/2-dependent and c-Jun-mediated mechanism. , 2010, American journal of physiology. Heart and circulatory physiology.
[126] A. J. White,et al. Attenuates Myocardial Ischemia / Reperfusion Injury and the Deposition of C-Reactive Protein in Areas of Infarction without Affecting Hemostasis , 2004 .
[127] G. Schmid-Schönbein,et al. Monocyte infiltration into venous valves. , 1998, Journal of vascular surgery.