Structural brain abnormalities in the common epilepsies assessed in a worldwide ENIGMA study

Structural MRI abnormalities are inconsistently reported in epilepsy. In the largest neuroimaging study to date, Whelan et al. report robust structural alterations across and within epilepsy syndromes, including shared volume loss in the thalamus, and widespread cortical thickness differences. The resulting neuroanatomical map will guide prospective studies of disease progression.

Neda Bernasconi | Peter Kochunov | Norman Delanty | Sebastien Ourselin | Luis Concha | Mario Mascalchi | Andrea Bernasconi | Dmitry Isaev | Neda Jahanshad | Terence J O'Brien | Orrin Devinsky | Thomas Thesen | Bernd Weber | Christian Rummel | Khalid Hamandi | Renzo Guerrini | Antonio Gambardella | Maria Eugenia Caligiuri | Andrea Cherubini | Roland Wiest | Philippe David | Matteo Lenge | Benjamin Bender | Fernando Cendes | Stefano Meletti | Andre Altmann | Paul M Thompson | Ingmar Blümcke | Pasquale Striano | Pascal Martin | Reetta Kälviäinen | Boris C Bernhardt | Jan Wagner | Carrie R McDonald | Junsong Zhang | Graeme D Jackson | Raviteja Kotikalapudi | Manuela Tondelli | Julie Absil | Sonya Foley | Patrick Kwan | Sanjay M Sisodiya | Sarah J Carr | Martin Domin | Mina Ryten | Angelo Labate | Anna Elisabetta Vaudano | Mark P Richardson | Ruben Kuzniecky | Niels K Focke | Simon S Keller | Derrek P Hibar | Anna Calvo | Yi Yao | Annamaria Vezzani | L. Concha | N. Jahanshad | P. Thompson | S. Ourselin | R. Kuzniecky | R. Wiest | G. Jackson | P. Kochunov | C. Yasuda | Marina K. M. Alvim | F. Cendes | P. Striano | B. Bender | D. Hibar | M. Mascalchi | M. Richardson | P. Kwan | O. Devinsky | T. Thesen | N. Bargalló | Guohao Zhang | S. Sisodiya | I. Blümcke | B. Weber | K. Blackmon | C. Carlson | A. Altmann | C. McDonald | A. Cherubini | K. Hamandi | M. Ryten | J. Absil | C. Depondt | G. Cavalleri | B. Bernhardt | T. O'Brien | J. Wagner | C. Whelan | S. Alhusaini | N. Delanty | M. Domin | A. Bernasconi | N. Bernasconi | A. Vaudano | C. Rummel | S. Keller | A. Calvo | S. Foley | C. Doherty | J. Botía | P. Auvinen | E. Bartolini | F. Bergo | Tauana Bernardes | B. Braga | M. Caligiuri | Sarah J A Carr | Jian Chen | Shuai Chen | P. David | Wendy França | G. Haaker | D. Isaev | R. Kotikalapudi | Magdalena A Kowalczyk | S. Langner | M. Lenge | K. M. Leyden | Min Liu | Richard Q. Loi | Pascal Martin | M. Morita | J. Pariente | Raúl Rodríguez-Cruces | Taavi Saavalainen | M. Semmelroch | M. Severino | R. Thomas | M. Tondelli | D. Tortora | L. Vivash | F. von Podewils | Yi Yao | N. Focke | A. Gambardella | R. Guerrini | R. Kälviäinen | A. Labate | S. Meletti | Junsong Zhang | A. Vezzani | Min Liu | Soenke Langner | Rhys H Thomas | Chad Carlson | Saud Alhusaini | Gianpiero L Cavalleri | Christopher D Whelan | Chantal Depondt | Nuria Bargalló | Guohao Zhang | Jian Chen | Barbara Braga | Kelly M Leyden | Colin P Doherty | Gerrit Haaker | Domenico Tortora | Emanuele Bartolini | Karen Blackmon | Lucy Vivash | Mariasavina Severino | Felix von Podewils | Clarissa L Yasuda | Juan A Botía | Marina K M Alvim | Pia Auvinen | Felipe P G Bergo | Tauana Bernardes | Shuai Chen | Wendy França | Richard Q Loi | Marcia E Morita | Jose C Pariente | Raul Rodríguez-Cruces | Taavi Saavalainen | Mira K Semmelroch | K. Leyden | R. Rodríguez-Cruces | M. Alvim | Y. Yao | T. O’Brien | S. Carr | P. Thompson | P. Thompson | Lucy E Vivash | P. Thompson | J. Wagner | P. Thompson | Sarah J. A. Carr | P. Thompson

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