Nasal cancer in the furniture and boot and shoe manufacturing industries.

Abstract The work reviewed in this paper has established beyond reasonable doubt the existence of a substantial risk of intranasal cancer in two groups of workers. These are, respectively, workers engaged in the manufacture of wooden furniture and in the manufacture of leather boots and shoes. In both, there is overwhelming evidence that the causative factor is in or associated with particles of dust. In the former case the dust comes principally from hardwoods, in the latter from leather, fibreboard, rubber, and cork. The existence of wood fibres in fibreboard may represent a link between these two industrial tumours. On the other hand the fact that in the furniture industry almost all the tumours are adenocarcinomas, while in the boot and shoe industry a wide range of histological varieties occurs, may indicate that the causative factors are different. It is important to point out that the environmental conditions which gave rise to the cases of intranasal cancer reported in this paper existed in the industry many years ago and may not necessarily still exist.

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