METTL1 promotes neuroblastoma development through m7G tRNA modification and selective oncogenic gene translation

[1]  Jianye Xu,et al.  A Comprehensive Analysis of METTL1 to Immunity and Stemness in Pan-Cancer , 2022, Frontiers in Immunology.

[2]  Zhenshuang Wang,et al.  Prognostic role of METTL1 in glioma , 2021, Cancer cell international.

[3]  Guojin Huang,et al.  Methyltransferase-like 1 regulates lung adenocarcinoma A549 cell proliferation and autophagy via the AKT/mTORC1 signaling pathway , 2021, Oncology letters.

[4]  Jonathan C. Schmok,et al.  Large-scale tethered function assays identify factors that regulate mRNA stability and translation , 2020, Nature Structural & Molecular Biology.

[5]  Jeppe Vinther No Evidence for N7-Methylation of Guanosine (m7G) in Human let-7e. , 2020, Molecular cell.

[6]  Gang Yin,et al.  Non-canonical signaling pathway of SNAI2 induces EMT in ovarian cancer cells by suppressing miR-222-3p transcription and upregulating PDCD10 , 2020, Theranostics.

[7]  R. Gregory,et al.  Nucleotide resolution profiling of m7G tRNA modification by TRAC-Seq , 2019, Nature Protocols.

[8]  Yun-Gui Yang,et al.  Dynamic methylome of internal mRNA N7-methylguanosine and its regulatory role in translation , 2019, Cell Research.

[9]  Anders Albrechtsen,et al.  Detection of internal N7-methylguanosine (m7G) RNA modifications by mutational profiling sequencing , 2019, Nucleic acids research.

[10]  Jun Chen,et al.  METTL1 overexpression is correlated with poor prognosis and promotes hepatocellular carcinoma via PTEN , 2019, Journal of Molecular Medicine.

[11]  Lulu Hu,et al.  Transcriptome-wide Mapping of Internal N7-Methylguanosine Methylome in Mammalian mRNA. , 2019, Molecular cell.

[12]  Du Hongmei,et al.  Genomic imprinting of neuroblastoma , 2019 .

[13]  W. Min,et al.  Dynamic m6A mRNA methylation reveals the role of METTL3-m6A-CDCP1 signaling axis in chemical carcinogenesis , 2019, Oncogene.

[14]  Gong Zhang,et al.  A peptide encoded by circular form of LINC-PINT suppresses oncogenic transcriptional elongation in glioblastoma , 2018, Nature Communications.

[15]  Kwok-Kin Wong,et al.  mRNA circularization by METTL3-eIF3h enhances translation and promotes oncogenesis , 2018, Nature.

[16]  Kristen M. Laricchia,et al.  Mutations in WDR4 as a new cause of Galloway–Mowat syndrome , 2018, American journal of medical genetics. Part A.

[17]  J. Szostak,et al.  Mettl1/Wdr4-Mediated m7G tRNA Methylome Is Required for Normal mRNA Translation and Embryonic Stem Cell Self-Renewal and Differentiation. , 2018, Molecular cell.

[18]  N. Sonenberg,et al.  Translational Control in Cancer. , 2018, Cold Spring Harbor perspectives in biology.

[19]  Tao Pan,et al.  Modifications and functional genomics of human transfer RNA , 2018, Cell Research.

[20]  Paul Schimmel,et al.  The emerging complexity of the tRNA world: mammalian tRNAs beyond protein synthesis , 2017, Nature Reviews Molecular Cell Biology.

[21]  William A. Flavahan,et al.  Epigenetic plasticity and the hallmarks of cancer , 2017, Science.

[22]  Jiwei Yu,et al.  Metadherin regulates actin cytoskeletal remodeling and enhances human gastric cancer metastasis via epithelial-mesenchymal transition , 2017, International journal of oncology.

[23]  J. Shohet,et al.  Neuroblastoma , 2017, British Medical Journal.

[24]  M. Pistillo,et al.  Epigenetic dysregulation in neuroblastoma: A tale of miRNAs and DNA methylation. , 2016, Biochimica et biophysica acta.

[25]  Sebastian A. Leidel,et al.  Elp3 links tRNA modification to IRES-dependent translation of LEF1 to sustain metastasis in breast cancer , 2016, The Journal of experimental medicine.

[26]  R. Gregory,et al.  The m(6)A Methyltransferase METTL3 Promotes Translation in Human Cancer Cells. , 2016, Molecular cell.

[27]  Wei Zhang,et al.  MicroRNA‐103 suppresses tumor cell proliferation by targeting PDCD10 in prostate cancer , 2016, The Prostate.

[28]  E. Phizicky,et al.  Mutation in WDR4 impairs tRNA m7G46 methylation and causes a distinct form of microcephalic primordial dwarfism , 2015, Genome Biology.

[29]  Fowzan S. Alkuraya,et al.  Mutation in WDR4 impairs tRNA m7G46 methylation and causes a distinct form of microcephalic primordial dwarfism , 2015, Genome Biology.

[30]  K. Cole,et al.  CASC15-S Is a Tumor Suppressor lncRNA at the 6p22 Neuroblastoma Susceptibility Locus. , 2015, Cancer research.

[31]  R. Gregory,et al.  Identification of small molecule inhibitors of Zcchc11 TUTase activity , 2015, RNA biology.

[32]  Xiaoyan Li,et al.  Knockdown of metadherin inhibits angiogenesis in breast cancer. , 2015, International journal of oncology.

[33]  A. Pertsemlidis,et al.  microRNA-449a functions as a tumor suppressor in neuroblastoma through inducing cell differentiation and cell cycle arrest , 2015, RNA biology.

[34]  Z. Ignatova,et al.  Emerging roles of tRNA in adaptive translation, signalling dynamics and disease , 2014, Nature Reviews Genetics.

[35]  T. Han,et al.  MTDH mediates trastuzumab resistance in HER2 positive breast cancer by decreasing PTEN expression through an NFκB-dependent pathway , 2014, BMC Cancer.

[36]  Gaurav Kumar Pandey,et al.  The risk-associated long noncoding RNA NBAT-1 controls neuroblastoma progression by regulating cell proliferation and neuronal differentiation. , 2014, Cancer cell.

[37]  M. Tatsuka,et al.  tRNA Modifying Enzymes, NSUN2 and METTL1, Determine Sensitivity to 5-Fluorouracil in HeLa Cells , 2014, PLoS Genetics.

[38]  Clement T Y Chan,et al.  A human tRNA methyltransferase 9-like protein prevents tumour growth by regulating LIN9 and HIF1-α , 2013, EMBO molecular medicine.

[39]  Zhike Lu,et al.  ALKBH5 is a mammalian RNA demethylase that impacts RNA metabolism and mouse fertility. , 2013, Molecular cell.

[40]  R. Stallings,et al.  Genome-wide promoter methylation analysis in neuroblastoma identifies prognostic methylation biomarkers , 2012, Genome Biology.

[41]  H. Carén,et al.  The RASSF gene family members RASSF5, RASSF6 and RASSF7 show frequent DNA methylation in neuroblastoma , 2012, Molecular Cancer.

[42]  M. Tatsuka,et al.  Frequent increased gene copy number and high protein expression of tRNA (cytosine-5-)-methyltransferase (NSUN2) in human cancers. , 2012, DNA and cell biology.

[43]  S. Gabriel,et al.  Whole exome sequencing identifies a splicing mutation in NSUN2 as a cause of a Dubowitz-like syndrome , 2012, Journal of Medical Genetics.

[44]  E. Phizicky,et al.  A domain of the actin binding protein Abp140 is the yeast methyltransferase responsible for 3-methylcytidine modification in the tRNA anti-codon loop. , 2011, RNA.

[45]  R. Stallings,et al.  MicroRNAs 10a and 10b are potent inducers of neuroblastoma cell differentiation through targeting of nuclear receptor corepressor 2 , 2011, Cell Death and Differentiation.

[46]  Robert H. Brown,et al.  RNA metabolism and the pathogenesis of motor neuron diseases , 2010, Trends in Neurosciences.

[47]  M. Cairns,et al.  Down-regulation of miR-17 family expression in response to retinoic acid induced neuronal differentiation. , 2009, Cellular signalling.

[48]  Yibin Kang,et al.  The Multifaceted Role of MTDH/AEG-1 in Cancer Progression , 2009, Clinical Cancer Research.

[49]  Weihua Jia,et al.  Overexpression of astrocyte elevated gene-1 (AEG-1) is associated with esophageal squamous cell carcinoma (ESCC) progression and pathogenesis. , 2009, Carcinogenesis.

[50]  Derek Y. Chiang,et al.  Astrocyte elevated gene-1 regulates hepatocellular carcinoma development and progression. , 2009, The Journal of clinical investigation.

[51]  Xianrang Song,et al.  Knockdown of astrocyte elevated gene-1 inhibits proliferation and enhancing chemo-sensitivity to cisplatin or doxorubicin in neuroblastoma cells , 2009, Journal of experimental & clinical cancer research : CR.

[52]  Michael Reiss,et al.  MTDH activation by 8q22 genomic gain promotes chemoresistance and metastasis of poor-prognosis breast cancer. , 2009, Cancer cell.

[53]  Barbara Hero,et al.  Histone Deacetylase 8 in Neuroblastoma Tumorigenesis , 2009, Clinical Cancer Research.

[54]  R. Place,et al.  Knockdown of astrocyte-elevated gene-1 inhibits prostate cancer progression through upregulation of FOXO3a activity , 2007, Oncogene.

[55]  T. Triche,et al.  Histone deacetylase 1 gene expression and sensitization of multidrug-resistant neuroblastoma cell lines to cytotoxic agents by depsipeptide. , 2007, Journal of the National Cancer Institute.

[56]  B. Brumback,et al.  Methylation of CASP8, DCR2, and HIN-1 in Neuroblastoma Is Associated with Poor Outcome , 2007, Clinical Cancer Research.

[57]  E. Phizicky,et al.  tRNA m7G methyltransferase Trm8p/Trm82p: evidence linking activity to a growth phenotype and implicating Trm82p in maintaining levels of active Trm8p. , 2005, RNA.

[58]  E. Phizicky,et al.  Two proteins that form a complex are required for 7-methylguanosine modification of yeast tRNA. , 2002, RNA.

[59]  Hilde van der Togt,et al.  Publisher's Note , 2003, J. Netw. Comput. Appl..