miR-146b Probably Assists miRNA-146a in the Suppression of Keratinocyte Proliferation and Inflammatory Responses in Psoriasis.

[1]  P. Nikamo,et al.  MicroRNA‐146a suppresses IL‐17–mediated skin inflammation and is genetically associated with psoriasis , 2017, The Journal of allergy and clinical immunology.

[2]  Norbert Meyer,et al.  Interleukins (from IL-1 to IL-38), interferons, transforming growth factor β, and TNF-α: Receptors, functions, and roles in diseases. , 2016, The Journal of allergy and clinical immunology.

[3]  T. Maimets,et al.  Pre-administration of PepFect6-microRNA-146a nanocomplexes inhibits inflammatory responses in keratinocytes and in a mouse model of irritant contact dermatitis. , 2016, Journal of controlled release : official journal of the Controlled Release Society.

[4]  Dong Joo Kim,et al.  Molecular Phenotyping Small (Asian) versus Large (Western) Plaque Psoriasis Shows Common Activation of IL-17 Pathway Genes, but Different Regulatory Gene Sets , 2015, The Journal of investigative dermatology.

[5]  K. Abram,et al.  MicroRNA-155 is Dysregulated in the Skin of Patients with Vitiligo and Inhibits Melanogenesis-associated Genes in Melanocytes and Keratinocytes. , 2016, Acta dermato-venereologica.

[6]  M. Lebwohl,et al.  Comparison of ixekizumab with etanercept or placebo in moderate-to-severe psoriasis (UNCOVER-2 and UNCOVER-3): results from two phase 3 randomised trials , 2015, The Lancet.

[7]  E. Izaurralde.  Breakers and blockers—miRNAs at work , 2015, Science.

[8]  A. Armstrong,et al.  Psoriasis and risk of diabetes-associated microvascular and macrovascular complications. , 2015, Journal of the American Academy of Dermatology.

[9]  W. Fu,et al.  Meta-Analysis of MicroRNA-146a rs2910164 G>C Polymorphism Association with Autoimmune Diseases Susceptibility, an Update Based on 24 Studies , 2015, PloS one.

[10]  Vinod Chandran,et al.  Enhanced meta-analysis and replication studies identify five new psoriasis susceptibility loci , 2015, Nature Communications.

[11]  M. Hafner,et al.  Laser capture microdissection followed by next‐generation sequencing identifies disease‐related microRNAs in psoriatic skin that reflect systemic microRNA changes in psoriasis , 2015, Experimental dermatology.

[12]  James T. Elder,et al.  Genome-wide Comparative Analysis of Atopic Dermatitis and Psoriasis Gives Insight into Opposing Genetic Mechanisms , 2015, American journal of human genetics.

[13]  S. Kõks,et al.  Melanocytes in the Skin – Comparative Whole Transcriptome Analysis of Main Skin Cell Types , 2014, PloS one.

[14]  C. Akdis,et al.  MicroRNA-146a alleviates chronic skin inflammation in atopic dermatitis through suppression of innate immune responses in keratinocytes. , 2014, The Journal of allergy and clinical immunology.

[15]  Sen Guo,et al.  A single-nucleotide polymorphism of miR-146a and psoriasis: an association and functional study , 2014, Journal of cellular and molecular medicine.

[16]  B. Elewski,et al.  Secukinumab in plaque psoriasis--results of two phase 3 trials. , 2014, The New England journal of medicine.

[17]  A. Pivarcsi,et al.  MiR-146a negatively regulates TLR2-induced inflammatory responses in keratinocytes. , 2014, The Journal of investigative dermatology.

[18]  T. Ridky,et al.  Kindler syndrome in mice and men , 2014, Cancer biology & therapy.

[19]  Michael R Green,et al.  miR-146a promotes the initiation and progression of melanoma by activating Notch signaling , 2014, eLife.

[20]  Shu-Chun Lin,et al.  miR-146a Enhances the Oncogenicity of Oral Carcinoma by Concomitant Targeting of the IRAK1, TRAF6 and NUMB Genes , 2013, PloS one.

[21]  C. Jung,et al.  MicroRNA-146b promotes adipogenesis by suppressing the SIRT1-FOXO1 cascade , 2013, EMBO molecular medicine.

[22]  F. Bazzoni,et al.  Negative regulation of Toll-like receptor 4 signaling by IL-10–dependent microRNA-146b , 2013, Proceedings of the National Academy of Sciences.

[23]  J. Krueger.  Hiding under the skin: A welcome surprise in psoriasis , 2012, Nature Medicine.

[24]  D. Salinger,et al.  Anti-IL-17 receptor antibody AMG 827 leads to rapid clinical response in subjects with moderate to severe psoriasis: results from a phase I, randomized, placebo-controlled trial. , 2012, The Journal of investigative dermatology.

[25]  A. Krogh,et al.  microRNA-146a inhibits G protein-coupled receptor-mediated activation of NF-κB by targeting CARD10 and COPS8 in gastric cancer , 2012, Molecular Cancer.

[26]  J. Ortonne,et al.  Brodalumab, an anti-interleukin-17-receptor antibody for psoriasis. , 2012, The New England journal of medicine.

[27]  David Baltimore,et al.  MicroRNAs, new effectors and regulators of NF‐κB , 2012, Immunological reviews.

[28]  Matti Pirinen,et al.  Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity , 2012 .

[29]  R. Kolde,et al.  MicroRNA Expression Profiles of Human Blood Monocyte-derived Dendritic Cells and Macrophages Reveal miR-511 as Putative Positive Regulator of Toll-like Receptor 4* , 2011, The Journal of Biological Chemistry.

[30]  Nan Shen,et al.  A Functional Variant in MicroRNA-146a Promoter Modulates Its Expression and Confers Disease Risk for Systemic Lupus Erythematosus , 2011, PLoS genetics.

[31]  J. Krueger,et al.  Contrasting pathogenesis of atopic dermatitis and psoriasis--part II: immune cell subsets and therapeutic concepts. , 2011, The Journal of allergy and clinical immunology.

[32]  P. Linsley,et al.  miR-146a is a significant brake on autoimmunity, myeloproliferation, and cancer in mice , 2011, The Journal of experimental medicine.

[33]  J. Krueger,et al.  Contrasting pathogenesis of atopic dermatitis and psoriasis--part I: clinical and pathologic concepts. , 2011, The Journal of allergy and clinical immunology.

[34]  C. Akdis,et al.  TNF-like weak inducer of apoptosis (TWEAK) and TNF-α cooperate in the induction of keratinocyte apoptosis. , 2011, The Journal of allergy and clinical immunology.

[35]  David Baltimore,et al.  Function of miR-146a in Controlling Treg Cell-Mediated Regulation of Th1 Responses , 2010, Cell.

[36]  S. Yuspa,et al.  Isolation and short-term culture of primary keratinocytes, hair follicle populations and dermal cells from newborn mice and keratinocytes from adult mice for in vitro analysis and for grafting to immunodeficient mice , 2008, Nature Protocols.

[37]  P. Janson,et al.  MicroRNAs: Novel Regulators Involved in the Pathogenesis of Psoriasis? , 2007, PloS one.

[38]  U. Schlötzer-Schrehardt,et al.  Kindlin-1 Is a Phosphoprotein Involved in Regulation of Polarity, Proliferation, and Motility of Epidermal Keratinocytes* , 2006, Journal of Biological Chemistry.

[39]  D. Baltimore,et al.  NF-κB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses , 2006, Proceedings of the National Academy of Sciences.