Pinholin S21 mutations induce structural topology and conformational changes.

[1]  I. Sahu,et al.  Conformational Differences Are Observed for the Active and Inactive Forms of Pinholin S21 Using DEER Spectroscopy. , 2020, The journal of physical chemistry. B.

[2]  Indra D Sahu,et al.  Structural Dynamics and Topology of the Inactive Form of S21 Holin in a Lipid Bilayer Using CW-EPR Spectroscopy. , 2020, The journal of physical chemistry. B.

[3]  I. Sahu,et al.  Active S2168 and inactive S21IRS pinholin interact differently with the lipid bilayer: A 31P and 2H solid state NMR study. , 2020, Biochimica et biophysica acta. Biomembranes.

[4]  Indra D Sahu,et al.  CW-EPR Spectroscopy Reveals the Structural Topology and Dynamic Properties of Active Pinholin S2168 in a Lipid Bilayer. , 2019, The journal of physical chemistry. B.

[5]  Indra D Sahu,et al.  Solid phase synthesis and spectroscopic characterization of the active and inactive forms of bacteriophage S21 pinholin protein. , 2019, Analytical biochemistry.

[6]  R. Young,et al.  Phage Lysis: Multiple Genes for Multiple Barriers. , 2019, Advances in virus research.

[7]  I. Sahu,et al.  Utilization of 13C-labeled amino acids to probe the α-helical local secondary structure of a membrane peptide using electron spin echo envelope modulation (ESEEM) spectroscopy. , 2018, Biochimica et biophysica acta. Biomembranes.

[8]  Indra D Sahu,et al.  Assessing topology and surface orientation of an antimicrobial peptide magainin 2 using mechanically aligned bilayers and electron paramagnetic resonance spectroscopy. , 2018, Chemistry and physics of lipids.

[9]  Indra D Sahu,et al.  Site-Directed Spin Labeling EPR for Studying Membrane Proteins , 2018, BioMed research international.

[10]  Indra D Sahu,et al.  Conformational changes of the HsDHODH N-terminal Microdomain via DEER Spectroscopy. , 2015, The journal of physical chemistry. B.

[11]  C. Tian,et al.  CW-EPR studies revealed different motional properties and oligomeric states of the integrin β1a transmembrane domain in detergent micelles or liposomes , 2015, Scientific Reports.

[12]  Indra D Sahu,et al.  Biophysical EPR Studies Applied to Membrane Proteins. , 2015, Journal of physical chemistry & biophysics.

[13]  Ry Young,et al.  Probing the Structure of the S105 Hole , 2014, Journal of bacteriology.

[14]  R. Young Phage lysis: Three steps, three choices, one outcome , 2014, Journal of Microbiology.

[15]  A. Holzenburg,et al.  Stable micron‐scale holes are a general feature of canonical holins , 2014, Molecular microbiology.

[16]  R. Young Phage lysis: do we have the hole story yet? , 2013, Current opinion in microbiology.

[17]  Indra D Sahu,et al.  DEER EPR measurements for membrane protein structures via bifunctional spin labels and lipodisq nanoparticles. , 2013, Biochemistry.

[18]  Indra D Sahu,et al.  Use of electron paramagnetic resonance to solve biochemical problems. , 2013, Biochemistry.

[19]  K. Pogliano,et al.  Visualization of pinholin lesions in vivo , 2013, Proceedings of the National Academy of Sciences.

[20]  Manoj Rajaure,et al.  The Spanin Complex Is Essential for Lambda Lysis , 2012, Journal of bacteriology.

[21]  Gunnar Jeschke,et al.  DEER distance measurements on proteins. , 2012, Annual review of physical chemistry.

[22]  D. Marsh Thermodynamics of phospholipid self-assembly. , 2012, Biophysical journal.

[23]  E. Bordignon Site-directed spin labeling of membrane proteins. , 2012, Topics in current chemistry.

[24]  Martha R. J. Clokie,et al.  Phages in nature , 2011, Bacteriophage.

[25]  Kit Pogliano,et al.  Holin triggering in real time , 2010, Proceedings of the National Academy of Sciences.

[26]  R. Young,et al.  Mapping the pinhole formation pathway of S21 , 2010, Molecular microbiology.

[27]  R. Young,et al.  Mutational analysis of the S21 pinholin , 2010, Molecular microbiology.

[28]  Ry Young,et al.  Structure of the lethal phage pinhole , 2009, Proceedings of the National Academy of Sciences.

[29]  Ryland Young,et al.  The final step in the phage infection cycle: the Rz and Rz1 lysis proteins link the inner and outer membranes , 2008, Molecular microbiology.

[30]  A. Holzenburg,et al.  The holin of bacteriophage lambda forms rings with large diameter , 2008, Molecular microbiology.

[31]  Ry Young,et al.  The Pinholin of Lambdoid Phage 21: Control of Lysis by Membrane Depolarization , 2007, Journal of bacteriology.

[32]  G. Jeschke,et al.  Distance measurements on spin-labelled biomacromolecules by pulsed electron paramagnetic resonance. , 2007, Physical chemistry chemical physics : PCCP.

[33]  D. Struck,et al.  Topological dynamics of holins in programmed bacterial lysis , 2006, Proceedings of the National Academy of Sciences.

[34]  H. Zimmermann,et al.  DeerAnalysis2006—a comprehensive software package for analyzing pulsed ELDOR data , 2006 .

[35]  Yun-Wei Chiang,et al.  The determination of pair distance distributions by pulsed ESR using Tikhonov regularization. , 2005, Journal of magnetic resonance.

[36]  I. Wang,et al.  Sizing the Holin Lesion with an Endolysin-β-Galactosidase Fusion , 2003 .

[37]  Jack H Freed,et al.  Protein structure determination using long-distance constraints from double-quantum coherence ESR: study of T4 lysozyme. , 2002, Journal of the American Chemical Society.

[38]  R. Young Bacteriophage holins: deadly diversity. , 2002, Journal of molecular microbiology and biotechnology.

[39]  G. Jeschke,et al.  Dead-time free measurement of dipole-dipole interactions between electron spins. , 2000, Journal of magnetic resonance.

[40]  I. Wang,et al.  Holins: the protein clocks of bacteriophage infections. , 2000, Annual review of microbiology.

[41]  K. J. Oh,et al.  Site-directed spin labeling of proteins. Applications to diphtheria toxin. , 2000, Methods in molecular biology.

[42]  N. Zhang,et al.  Complementation and characterization of the nested Rz and Rz1 reading frames in the genome of bacteriophage λ , 1999, Molecular and General Genetics MGG.

[43]  U. Bläsi,et al.  Functional assembly of the λ S holin requires periplasmic localization of its N-terminus , 1999, Archives of Microbiology.

[44]  J. Feix,et al.  Mapping of the residues involved in a proposed beta-strand located in the ferric enterobactin receptor FepA using site-directed spin-labeling. , 1997, Biochemistry.

[45]  U. Bläsi,et al.  Two beginnings for a single purpose: the dual‐start holins in the regulation of phage lysis , 1996, Molecular microbiology.

[46]  R. Young,et al.  S gene expression and the timing of lysis by bacteriophage lambda , 1995, Journal of bacteriology.

[47]  H. Khorana,et al.  A collision gradient method to determine the immersion depth of nitroxides in lipid bilayers: application to spin-labeled mutants of bacteriorhodopsin. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[48]  C. Altenbach,et al.  Investigation of structure and dynamics in membrane proteins using site-directed spin labeling , 1994 .

[49]  R. Young Bacteriophage lysis: mechanism and regulation , 1992 .

[50]  H. Khorana,et al.  Transmembrane protein structure: spin labeling of bacteriorhodopsin mutants. , 1990, Science.

[51]  E. Evans,et al.  Thermomechanical and transition properties of dimyristoylphosphatidylcholine/cholesterol bilayers. , 1988, Biochemistry.