ROCK and JAK1 signaling cooperate to control actomyosin contractility in tumor cells and stroma.
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Erik Sahai | Victoria Sanz-Moreno | Steven Hooper | Richard Marais | E. Sahai | C. Marshall | R. Marais | S. Hooper | V. Sanz-Moreno | J. Larkin | R. Mitter | C. Gaggioli | Amaya Viros | James Larkin | A. Virós | Cedric Gaggioli | G. Meneguzzi | Richard Mitter | Fredrik Wallberg | Maggie Yeo | Jean Albrengues | Chloé C Féral | Martin Cook | Guerrino Meneguzzi | Chris J Marshall | C. Féral | Fredrik Wållberg | Jean Albrengues | Maggie Yeo | Martin G. Cook
[1] Peter Olson,et al. Cancer-Associated Fibroblasts Are Activated in Incipient Neoplasia to Orchestrate Tumor-Promoting Inflammation in an NF-kappaB-Dependent Manner. , 2010, Cancer cell.
[2] R. Torres,et al. The Rho exchange factor Arhgef1 mediates the effects of angiotensin II on vascular tone and blood pressure , 2010, Nature Medicine.
[3] M. Karin,et al. Inflammation and oncogenesis: a vicious connection. , 2010, Current opinion in genetics & development.
[4] P. Friedl,et al. The Journal of Cell Biology , 2002 .
[5] E. Sahai,et al. A chemical biology screen reveals a role for Rab21-mediated control of actomyosin contractility in fibroblast-driven cancer invasion , 2009, British Journal of Cancer.
[6] James E. Thompson and. Photochemical Preparation of a Pyridone Containing Tetracycle: A Jak Protein Kinase Inhibitor. , 2010 .
[7] Larry Norton,et al. Tumor Self-Seeding by Circulating Cancer Cells , 2009, Cell.
[8] Hua Yu,et al. STATs in cancer inflammation and immunity: a leading role for STAT3 , 2009, Nature Reviews Cancer.
[9] H. Drexler,et al. Hepatocyte gp130 Deficiency Reduces Vascular Remodeling After Carotid Artery Ligation , 2009, Hypertension.
[10] E. Sahai,et al. Intravital imaging reveals transient changes in pigment production and Brn2 expression during metastatic melanoma dissemination. , 2009, Cancer research.
[11] M. Bar‐eli,et al. Inflammation and melanoma metastasis , 2009, Pigment cell & melanoma research.
[12] Timothy C Wang,et al. Inflammation and cancer: IL-6 and STAT3 complete the link. , 2009, Cancer cell.
[13] M. Karin,et al. IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-associated cancer. , 2009, Cancer cell.
[14] Ozge Canli,et al. gp130-mediated Stat3 activation in enterocytes regulates cell survival and cell-cycle progression during colitis-associated tumorigenesis. , 2009, Cancer cell.
[15] B. Aggarwal,et al. Targeting Inflammatory Pathways for Prevention and Therapy of Cancer: Short-Term Friend, Long-Term Foe , 2009, Clinical Cancer Research.
[16] P. Yue,et al. Targeting STAT3 in cancer: how successful are we? , 2009, Expert opinion on investigational drugs.
[17] M. Feldman,et al. Activated STAT3 is a mediator and biomarker of VEGF endothelial activation , 2008, Cancer biology & therapy.
[18] N. Todd,et al. Mechanisms of Oncostatin M-Induced Pulmonary Inflammation and Fibrosis , 2008, The Journal of Immunology.
[19] E. Sahai,et al. Rac Activation and Inactivation Control Plasticity of Tumor Cell Movement , 2008, Cell.
[20] E. Sahai,et al. Imaging amoeboid cancer cell motility in vivo , 2008, Journal of microscopy.
[21] Jane Fridlyand,et al. Improving Melanoma Classification by Integrating Genetic and Morphologic Features , 2008, PLoS medicine.
[22] K. Venkatasubbarao,et al. Inhibition of STAT3 Tyr705 phosphorylation by Smad4 suppresses transforming growth factor beta-mediated invasion and metastasis in pancreatic cancer cells. , 2008, Cancer research.
[23] Ying-Xuan Chen,et al. Inhibition of JAK1, 2/STAT3 signaling induces apoptosis, cell cycle arrest, and reduces tumor cell invasion in colorectal cancer cells. , 2008, Neoplasia.
[24] Xin-Yun Huang,et al. Identification of Novel Direct Stat3 Target Genes for Control of Growth and Differentiation* , 2008, Journal of Biological Chemistry.
[25] H. Zhang,et al. Fra-1 and Stat3 synergistically regulate activation of human MMP-9 gene. , 2008, Molecular immunology.
[26] E. Sahai,et al. Fibroblast-led collective invasion of carcinoma cells with differing roles for RhoGTPases in leading and following cells , 2007, Nature Cell Biology.
[27] N. Coleman,et al. Gain and overexpression of the oncostatin M receptor occur frequently in cervical squamous cell carcinoma and are associated with adverse clinical outcome , 2007, The Journal of pathology.
[28] D. Radisky,et al. Fibrosis and cancer: Do myofibroblasts come also from epithelial cells via EMT? , 2007, Journal of cellular biochemistry.
[29] J. Scheller,et al. The IL-6/sIL-6R complex as a novel target for therapeutic approaches , 2007, Expert opinion on therapeutic targets.
[30] T. Nakayama,et al. Expression of p-STAT3 in human gastric carcinoma: significant correlation in tumour invasion and prognosis. , 2007, International journal of oncology.
[31] Paolo P. Provenzano,et al. Collagen reorganization at the tumor-stromal interface facilitates local invasion , 2006, BMC medicine.
[32] J. Bromberg,et al. Pyridone 6, a pan-Janus-activated kinase inhibitor, induces growth inhibition of multiple myeloma cells. , 2006, Cancer research.
[33] John S. Condeelis,et al. ROCK- and Myosin-Dependent Matrix Deformation Enables Protease-Independent Tumor-Cell Invasion In Vivo , 2006, Current Biology.
[34] Raghu Kalluri,et al. Fibroblasts in cancer , 2006, Nature Reviews Cancer.
[35] M. Olson,et al. Conditional regulation of a ROCK-estrogen receptor fusion protein. , 2006, Methods in enzymology.
[36] C. Marshall,et al. Cdc42–MRCK and Rho–ROCK signalling cooperate in myosin phosphorylation and cell invasion , 2005, Nature Cell Biology.
[37] Michael P. Sheetz,et al. Basic mechanism of three-dimensional collagen fibre transport by fibroblasts , 2005, Nature Cell Biology.
[38] 伊藤 美幸. Requirement of STAT3 activation for maximal collagenase-1 (MMP-1) induction by epidermal growth factor and malignant characteristics in T24 bladder cancer cells , 2005 .
[39] Gordon K. Smyth,et al. limma: Linear Models for Microarray Data , 2005 .
[40] O. Silvennoinen,et al. The Janus kinases (Jaks) , 2004, Genome Biology.
[41] Jean YH Yang,et al. Bioconductor: open software development for computational biology and bioinformatics , 2004, Genome Biology.
[42] J. Bromberg,et al. Stat3 is required for the development of skin cancer. , 2004, The Journal of clinical investigation.
[43] Michael Karin,et al. IKKβ Links Inflammation and Tumorigenesis in a Mouse Model of Colitis-Associated Cancer , 2004, Cell.
[44] F. Ali-Osman,et al. Stat3 activation regulates the expression of matrix metalloproteinase-2 and tumor invasion and metastasis , 2004, Oncogene.
[45] D. Hartshorne,et al. Myosin phosphatase: Structure, regulation and function , 2004, Molecular and Cellular Biochemistry.
[46] Benjamin M. Bolstad,et al. affy - analysis of Affymetrix GeneChip data at the probe level , 2004, Bioinform..
[47] R. Mason,et al. Oncostatin M, a cytokine released by activated mononuclear cells, induces epithelial cell-myofibroblast transdifferentiation via Jak/Stat pathway activation. , 2004, Journal of the American Society of Nephrology : JASN.
[48] L. Coussens,et al. The tumor microenvironment: a critical determinant of neoplastic evolution. , 2003, European journal of cell biology.
[49] P. Friedl,et al. Proteolytic and non-proteolytic migration of tumour cells and leucocytes. , 2003, Biochemical Society symposium.
[50] Erik Sahai,et al. Differing modes of tumour cell invasion have distinct requirements for Rho/ROCK signalling and extracellular proteolysis , 2003, Nature Cell Biology.
[51] Olivier De Wever,et al. Role of tissue stroma in cancer cell invasion , 2003, The Journal of pathology.
[52] Frederick Grinnell,et al. Fibroblast biology in three-dimensional collagen matrices. , 2003, Trends in cell biology.
[53] P. Friedl,et al. Tumour-cell invasion and migration: diversity and escape mechanisms , 2003, Nature Reviews Cancer.
[54] Timothy J Mitchison,et al. Dissecting Temporal and Spatial Control of Cytokinesis with a Myosin II Inhibitor , 2003, Science.
[55] Peter Friedl,et al. Compensation mechanism in tumor cell migration , 2003, The Journal of cell biology.
[56] Massimo Gadina,et al. Cytokine Signaling in 2002 New Surprises in the Jak/Stat Pathway , 2002, Cell.
[57] R. Perona,et al. Simultaneous tyrosine and serine phosphorylation of STAT3 transcription factor is involved in Rho A GTPase oncogenic transformation. , 2001, Molecular biology of the cell.
[58] H. L. Vos,et al. A STAT-responsive Element in the Promoter of the Episialin/MUC1 Gene Is Involved in Its Overexpression in Carcinoma Cells* , 2001, The Journal of Biological Chemistry.
[59] J. Darnell,et al. Stat3 as an Oncogene , 1999, Cell.
[60] M. Herlyn,et al. Immunohistochemical evidence of cytokine networks during progression of human melanocytic lesions , 1999, International journal of cancer.
[61] J. Turkson,et al. Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells. , 1999, Immunity.
[62] M. Goldsmith,et al. Janus kinases in interleukin-2-mediated signaling: JAK1 and JAK3 are differentially regulated by tyrosine phosphorylation , 1997, Current Biology.
[63] C. O’Brien,et al. Isolation and Characterization of the Human gp130 Promoter , 1997, The Journal of Biological Chemistry.
[64] Comeau,et al. The IL-6 signal transducer, gp130: an oncostatin M receptor and affinity converter for the LIF receptor. , 1992, Science.
[65] I. M. Neiman,et al. [Inflammation and cancer]. , 1974, Patologicheskaia fiziologiia i eksperimental'naia terapiia.