Assessment of Maternal Heart-Rate Variability during Labor Using Wavelet-Based Power Spectral Analysis

Objective: Changes in the maternal cardiac autonomic nervous system were assessed in the presence and absence of uterine contractions by analyzing maternal heart-rate variability during labor using wavelet-based power spectral analysis. Methods: We assessed the heart-rate variability in 20 pregnant women during labor and in 15 pregnant women with threatened premature labor with the use of wavelet-based power spectral analysis. Results: There was no significant difference in high-frequency components between the uterine contraction and non-contraction periods. The intensities of the low-frequency and very-low-frequency components during uterine contractions were significantly stronger than the corresponding intensities between uterine contractions. Conclusion: Maternal sympathetic activity was upregulated during uterine contractions, and influenced the very-low-frequency components. This method of analysis may represent a novel means of identifying uterine contractions.

[1]  D. Adam,et al.  Assessment of autonomic function in humans by heart rate spectral analysis. , 1985, The American journal of physiology.

[2]  E. Quilligan,et al.  Cardiac output during labor. , 1956, Surgical forum.

[3]  A. Malliani,et al.  Cardiovascular Neural Regulation Explored in the Frequency Domain , 1991, Circulation.

[4]  R. Rokey,et al.  Maternal hemodynamic effects of uterine contractions by M-mode and pulsed-Doppler echocardiography. , 1990, American journal of obstetrics and gynecology.

[5]  G. Breithardt,et al.  Heart rate variability: standards of measurement, physiological interpretation and clinical use. Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology. , 1996 .

[6]  S Hunter,et al.  Cardiac output during labour. , 1987, British medical journal.

[7]  G. Varigos,et al.  Sinus Arrhythmia in Acute Myocardial Infarction , 1978, The Medical journal of Australia.

[8]  S Cerutti,et al.  Analysis of short-term oscillations of R-R and arterial pressure in conscious dogs. , 1990, The American journal of physiology.

[9]  A. Aviv,et al.  Plasmin-platelet interaction involves cleavage of functional thrombin receptor. , 1996, The American journal of physiology.

[10]  K. Ueland,et al.  Maternal cardiovascular dynamics: III. Labor and delivery under local and caudal analgesia , 1969 .

[11]  J. Kentish,et al.  Effects of changes of pH on the contractile function of cardiac muscle. , 1990, The American journal of physiology.

[12]  Jens Kjeldsen.  Hemodynamic investigations during labour and delivery , 1979, Acta obstetricia et gynecologica Scandinavica. Supplement.

[13]  D. Morlet,et al.  Wavelet analysis of high-resolution ECGs in post-infarction patients: role of the basic wavelet and of the analyzed lead. , 1995, International journal of bio-medical computing.

[14]  R. Cohen,et al.  Power spectrum analysis of heart rate fluctuation: a quantitative probe of beat-to-beat cardiovascular control. , 1981, Science.

[15]  D G Chaffin,et al.  The dimension of chaos in the fetal heart rate. , 1991, American journal of obstetrics and gynecology.

[16]  Françoise Peyrin,et al.  Wavelet analysis of high-resolution signal-averaged ECGs in postinfarction patients. , 1993, Journal of electrocardiology.

[17]  Shlomo Havlin,et al.  Scaling behaviour of heartbeat intervals obtained by wavelet-based time-series analysis , 1996, Nature.

[18]  Wang Li,et al.  The study of maternal and fetal plasma catecholamines levels during pregnancy and delivery , 1999 .

[19]  U. Lundberg,et al.  Catecholamine and cortisol reaction to childbirth , 2001 .

[20]  E. Fallen,et al.  Power spectral analysis of heart rate variability: a noninvasive signature of cardiac autonomic function. , 1993, Critical reviews in biomedical engineering.

[21]  Stewart Hunter,et al.  Adaptation of the maternal heart in pregnancy , 1992, British heart journal.

[22]  J. Saul,et al.  Beat-to-Beat Variations of Heart Rate Reflect Modulation of Cardiac Autonomic Outflow , 1990 .

[23]  D L Eckberg,et al.  Mechanisms underlying very-low-frequency RR-interval oscillations in humans. , 1998, Circulation.

[24]  T Suzuki,et al.  Power spectral analysis for autonomic influences in heart rate and blood pressure variability in fetal lambs. , 1996, The American journal of physiology.

[25]  P. Schwartz,et al.  Single cardiac vagal fiber activity, acute myocardial ischemia, and risk for sudden death. , 1991, Circulation research.

[26]  B. W. Hyndman,et al.  Spontaneous Rhythms in Physiological Control Systems , 1971, Nature.

[27]  I. Merkatz,et al.  Diminished respiratory sinus arrhythmia in asphyxiated term infants. , 1986, American journal of obstetrics and gynecology.

[28]  Yoshitaka Kimura,et al.  Time-frequency analysis of fetal heartbeat fluctuation using wavelet transform. , 1998, American journal of physiology. Heart and circulatory physiology.

[29]  R J Cohen,et al.  Beat to beat variability in cardiovascular variables: noise or music? , 1989, Journal of the American College of Cardiology.

[30]  A. Malliani,et al.  Heart rate variability. Standards of measurement, physiological interpretation, and clinical use , 1996 .

[31]  V Pichot,et al.  Wavelet transform to quantify heart rate variability and to assess its instantaneous changes. , 1999, Journal of applied physiology.

[32]  Jeff Davies.  Reproduced with the permission of Bird life Australia and , 2013 .