DNA topoisomerase I inhibitors from Rinorea anguifera.

[1]  S. Hecht,et al.  Camptothecin: current perspectives. , 2004, Bioorganic & medicinal chemistry.

[2]  D. Kingston,et al.  Use of COMPARE analysis to discover new natural product drugs: isolation of camptothecin and 9-methoxycamptothecin from a new source. , 2000, Journal of natural products.

[3]  J. Champoux,et al.  Novel insights into catalytic mechanism from a crystal structure of human topoisomerase I in complex with DNA. , 2000, Biochemistry.

[4]  D. Kingston,et al.  Isolation and biochemical characterization of a new topoisomerase I inhibitor from Ocotea leucoxylon. , 2000, Journal of natural products.

[5]  I. Yoo,et al.  An antioxidant lignan and other constituents from the root bark of Hibiscus syriacus. , 1999, Planta medica.

[6]  H. J. Park,et al.  Studies on constituents with cytotoxic activity from the stem bark of Syringa velutina. , 1999, Chemical & pharmaceutical bulletin.

[7]  Y. Pommier,et al.  Mechanism of action of eukaryotic DNA topoisomerase I and drugs targeted to the enzyme. , 1998, Biochimica et biophysica acta.

[8]  J. Berger Structure of DNA topoisomerases. , 1998, Biochimica et biophysica acta.

[9]  J. Nitiss Investigating the biological functions of DNA topoisomerases in eukaryotic cells. , 1998, Biochimica et biophysica acta.

[10]  J. Champoux Domains of human topoisomerase I and associated functions. , 1998, Progress in nucleic acid research and molecular biology.

[11]  B. Bodo,et al.  DNA topoisomerase I inhibitors: cytotoxic flavones from Lethedon tannaensis. , 1996, Journal of natural products.

[12]  J. Köhrle,et al.  Selected Novel Flavones Inhibit the DNA Binding or the DNA Religation Step of Eukaryotic Topoisomerase I (*) , 1996, The Journal of Biological Chemistry.

[13]  Y. Pommier,et al.  Eukaryotic DNA topoisomerases I. , 1995, Biochimica et biophysica acta.

[14]  G. Cordell,et al.  (-)-Roemerine, an aporphine alkaloid from Annona senegalensis that reverses the multidrug-resistance phenotype with cultured cells. , 1995, Journal of natural products.

[15]  R. Mehta,et al.  Flavonoids as DNA topoisomerase antagonists and poisons: structure-activity relationships. , 1995, Journal of natural products.

[16]  L. Fisher,et al.  Site-specific DNA cleavage by mammalian DNA topoisomerase II induced by novel flavone and catechin derivatives. , 1992, The Biochemical journal.

[17]  H. Wagner,et al.  Synthesis of biologically active tetrahydro-furofuranlignan-(syringin, pinoresinol)- mono- and bis-glucosides , 1991 .

[18]  Yamashita Yoshinori,et al.  Induction of mammalian topoisomerase II dependent DNA cleavage by nonintercalative flavonoids, genistein and orobol. , 1990 .

[19]  K. Yasukawa,et al.  Two flavonol glycosides from Lysimachia nummularia , 1990 .

[20]  L. Liu,et al.  Topoisomerase-targeting antitumor drugs. , 1989, Biochimica et biophysica acta.

[21]  R. Hertzberg,et al.  On the mechanism of topoisomerase I inhibition by camptothecin: evidence for binding to an enzyme-DNA complex. , 1989, Biochemistry.

[22]  L. Liu,et al.  DNA topoisomerase poisons as antitumor drugs. , 1989, Annual review of biochemistry.

[23]  T. Deyama,et al.  The Constituents of Eucommia ulmoides OLIV. V. Isolation of Dihydroxydehydrodiconiferyl Alcohol Isomers and Phenolic Compounds , 1987 .

[24]  K. Yasukawa,et al.  A flavonol glycoside from Lysimachia Mauritiana , 1987 .

[25]  R. Hertzberg,et al.  Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I. , 1985, The Journal of biological chemistry.

[26]  T. Deyama,et al.  The constituents of Eucommia ulmoides OLIV. II. Isolation and structures of three new lignan glycosides. , 1985 .

[27]  T. Deyama The Constituents of Eucommia ulmoides OLIV. I. Isolation of (+)-Medioresinol Di-O-β-D-glucopyranoside , 1983 .

[28]  A. McPhail,et al.  Plant Antitumor Agents. I. The Isolation and Structure of Camptothecin, a Novel Alkaloidal Leukemia and Tumor Inhibitor from Camptotheca acuminata1,2 , 1966 .