Fish consumption as a source of human exposure to perfluorinated alkyl substances in Sweden - analysis of edible fish from Lake Vättern and the Baltic Sea.

Perfluorinated alkyl substances (PFAS) were analyzed in muscle tissue from edible fish species caught in the second largest freshwater lake in Sweden, Lake Vättern (LV), and in the brackish water Baltic Sea (BS). Perfluorooctane sulfonate (PFOS) was the predominant PFAS found. PFOS concentrations were higher in LV (medians 2.9-12 ng g(-1) fresh weight) than in BS fish (medians 1.0-2.5 ng g(-1) fresh weight). Moreover, LV fish was more contaminated with several other PFAS than BS fish. This may be due to anthropogenic discharges from urban areas around LV. The PFAS pattern differed between LV and BS fish, indicating different sources of contamination for the two study areas. Human exposure to PFOS via fish intake was calculated for three study groups, based on consumption data from literature. The groups consisted of individuals that reported moderate or high consumption of BS fish or high consumption of LV fish, respectively. The results showed that PFOS intake strongly depended on individual fish consumption as well as the fish catchment area. Median PFOS intakes were estimated to 0.15 and 0.62 ng kg(-1) body weight (bw) d(-1) for the consumers of moderate and high amounts of BS fish, respectively. For the group with high consumption of LV fish a median PFOS intake of 2.7 ng kg(-1)bw d(-1) was calculated. Fish consumption varied considerably within the consumer groups, with maximum PFOS intakes of 4.5 (BS fish) or 9.6 ng kg(-1)bw d(-1) (LV fish). Comparison of our results with literature data on PFOS intake from food suggests that fish from contaminated areas may be a significant source of dietary PFOS exposure.

[1]  Derek C G Muir,et al.  Biological monitoring of polyfluoroalkyl substances: A review. , 2006, Environmental science & technology.

[2]  H. Viberg,et al.  Perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA) , 2011 .

[3]  P. Larsson,et al.  Monitoring of Persistent Organic Pollutants (POPs): Examples from Lake Vättern, Sweden , 2001, Ambio.

[4]  J. Giesy,et al.  Global distribution of perfluorooctane sulfonate in wildlife. , 2001, Environmental science & technology.

[5]  Ian Stirling,et al.  Rapid response of Arctic ringed seals to changes in perfluoroalkyl production. , 2007, Environmental science & technology.

[6]  Timothy J Wallington,et al.  Degradation of fluorotelomer alcohols: a likely atmospheric source of perfluorinated carboxylic acids. , 2004, Environmental science & technology.

[7]  Martin Scheringer,et al.  Estimating the contribution of precursor compounds in consumer exposure to PFOS and PFOA. , 2008, Chemosphere.

[8]  Scott A Mabury,et al.  Spatial distribution of perfluoroalkyl contaminants in lake trout from the Great Lakes. , 2007, Environmental science & technology.

[9]  Bernhard Liebl,et al.  Exposure of an adult population to perfluorinated substances using duplicate diet portions and biomonitoring data. , 2007, Environmental science & technology.

[10]  R. Bossi,et al.  Perfluoroalkyl compounds in Danish wastewater treatment plants and aquatic environments. , 2008, Environment international.

[11]  S. Tittlemier,et al.  Dietary exposure of Canadians to perfluorinated carboxylates and perfluorooctane sulfonate via consumption of meat, fish, fast foods, and food items prepared in their packaging. , 2007, Journal of agricultural and food chemistry.

[12]  Q. Jiang,et al.  Persistent perfluorinated acids in seafood collected from two cities of China. , 2006, Environmental science & technology.

[13]  Wenyue Hu,et al.  Binding of perfluorinated fatty acids to serum proteins , 2003, Environmental toxicology and chemistry.

[14]  S. Tittlemier,et al.  Cooking decreases observed perfluorinated compound concentrations in fish. , 2008, Journal of agricultural and food chemistry.

[15]  Nobuyoshi Yamashita,et al.  Is fish a major source of fluorinated surfactants and repellents in humans living on the Baltic Coast? , 2006, Environmental science & technology.

[16]  H. Peltonen,et al.  Predicting effects of exploitation rate on weight-at-age, population dynamics, and bioaccumulation of PCDD/Fs and PCBs in herring (Clupea harengus L.) in the Northern Baltic Sea. , 2007, Environmental science & technology.

[17]  U. Berger,et al.  Tissue distribution of perfluorinated surfactants in common guillemot (Uria aalge) from the Baltic Sea. , 2008, Environmental science & technology.

[18]  Tom Harner,et al.  Indoor and outdoor air concentrations and phase partitioning of perfluoroalkyl sulfonamides and polybrominated diphenyl ethers. , 2004, Environmental science & technology.

[19]  R. Blust,et al.  Perfluorooctane sulfonic acid in bib (Trisopterus luscus) and plaice (Pleuronectes platessa) from the Western Scheldt and the Belgian North Sea: Distribution and biochemical effects , 2003, Environmental toxicology and chemistry.

[20]  R. Döscher,et al.  The Baltic haline conveyor belt or the overturning circulation and mixing in the Baltic. , 2004, Ambio.

[21]  J. V. Vanden Heuvel,et al.  Tissue distribution, metabolism, and elimination of perfluorooctanoic acid in male and female rats. , 1991, Journal of biochemical toxicology.

[22]  Urs Berger,et al.  Trends of perfluorinated alkyl substances in herring gull eggs from two coastal colonies in northern Norway: 1983-2003. , 2007, Environmental science & technology.

[23]  Martí Nadal,et al.  Human exposure to perfluorinated chemicals through the diet: intake of perfluorinated compounds in foods from the Catalan (Spain) market. , 2008, Journal of agricultural and food chemistry.

[24]  Konstantinos Prevedouros,et al.  Sources, Fate and Transport of Perfluorocarboxylates , 2006 .

[25]  D. Schrenk,et al.  Opinion of the Scientific Panel on Contaminants in the Food chain on perfluorooctane sulfonate (PFOS), perfluorooctanoic acid (PFOA) and their salts , 2008 .

[26]  E. Kissa,et al.  Fluorinated Surfactants and Repellents , 2001 .

[27]  Scott A Mabury,et al.  Bioconcentration and tissue distribution of perfluorinated acids in rainbow trout (Oncorhynchus mykiss) , 2003, Environmental toxicology and chemistry.

[28]  R. Rosenberg,et al.  Bioturbation-driven release of organic contaminants from Baltic Sea sediments mediated by the invading polychaete Marenzelleria neglecta. , 2008, Environmental science & technology.

[29]  M. Schlummer,et al.  TISSUE DISTRIBUTION OF PERFLUOROOCTANSULFONATE (PFOS) AND PERFLUOROOCTANOIC ACID (PFOA) IN FISH , 2007 .

[30]  Martin Kraft,et al.  Biomonitoring of Perfluorinated Compounds in Children and Adults Exposed to Perfluorooctanoate-Contaminated Drinking Water , 2008, Environmental health perspectives.

[31]  E. Petersson,et al.  The timing of spawning migration: implications of environmental variation, life history, and sex , 2004 .

[32]  M. A. Mohd,et al.  Perfluorooctanesulfonate and related fluorochemicals in human blood from several countries. , 2004, Environmental science & technology.

[33]  J. Giesy,et al.  Perfluorinated Compounds in Aquatic Organisms at Various Trophic Levels in a Great Lakes Food Chain , 2005, Archives of environmental contamination and toxicology.

[34]  Keith Solomon,et al.  Temporal trends of perfluoroalkyl contaminants in polar bears (Ursus maritimus) from two locations in the North American Arctic, 1972-2002. , 2006, Environmental science & technology.