Integrated genomic analysis identifies deregulated JAK/STAT-MYC-biosynthesis axis in aggressive NK-cell leukemia
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Ding Ma | Lili Dong | Gang Huang | Jie Jin | Na Wang | Jianfeng Zhou | Zhen Shang | Jianlin He | Shaoping Ling | Lihua Cao | Weili Zhao | Jie Jin | G. Qing | Shaoping Ling | D. Ma | Lingtong Hao | Lili Dong | Lihua Cao | Jun Wu | Jianfeng Zhou | Xin Du | L. Qiu | Jun Wu | Lingtong Hao | Qifa Liu | Qian-fei Wang | Gang Huang | Yi Luo | Jianyong Li | Lugui Qiu | Guoliang Qing | Liang Huang | Dan Liu | Yuting Tang | Hui Luo | Xuelian Hu | Lingshuang Sheng | Lijun Zhu | Di Wang | Yi Luo | Min Xiao | Xia Mao | Kuangguo Zhou | Xinchang Zheng | Pinpin Sui | Shanlan Mo | Jin Yan | Qilin Ao | Hongsheng Zhou | Hongyu Zhang | Jianyong Li | Li Fu | Weili Zhao | Jieping Chen | Xin Du | Hudan Liu | Xin Liu | Qian-fei Wang | Q. Ao | Liang Huang | Z. Shang | M. Xiao | L. Sheng | Hui Luo | Lijun Zhu | L. Fu | Kuangguo Zhou | Hudan Liu | X. Mao | Yuting Tang | Na Wang | Xuelian Hu | Jin Yan | Xin Liu | Dan Liu | Di Wang | Xinchang Zheng | Qi-fa Liu | Hong-sheng Zhou | Jianlin He | Hong-yu Zhang | Pinpin Sui | Shanlan Mo | Jieping Chen | H. Luo | X. Du | S. Mo | Guoliang Qing
[1] Qian Zhang,et al. GSA: Genome Sequence Archive* , 2017, Genom. Proteom. Bioinform..
[2] M. Salto‐Tellez,et al. RUNX3 is oncogenic in natural killer/T-cell lymphoma and is transcriptionally regulated by MYC , 2017, Leukemia.
[3] Michael P. Lisanti,et al. Cancer metabolism: a therapeutic perspective , 2017, Nature Reviews Clinical Oncology.
[4] Can Küçük,et al. Clinicopathologic Characterization of Aggressive Natural Killer Cell Leukemia Involving Different Tissue Sites , 2016, The American journal of surgical pathology.
[5] K. Sakamoto,et al. Frequent BCOR aberrations in extranodal NK/T‐Cell lymphoma, nasal type , 2016, Genes, chromosomes & cancer.
[6] R. Siebert,et al. Genes encoding members of the JAK‐STAT pathway or epigenetic regulators are recurrently mutated in T‐cell prolymphocytic leukaemia , 2016, British journal of haematology.
[7] Xuemei Lu,et al. Extremely high genetic diversity in a single tumor points to prevalence of non-Darwinian cell evolution , 2015, Proceedings of the National Academy of Sciences.
[8] C. Dang,et al. MYC, Metabolism, and Cancer. , 2015, Cancer discovery.
[9] F. Delhommeau,et al. Effect of mutation order on myeloproliferative neoplasms. , 2015, The New England journal of medicine.
[10] A. Lane,et al. Pyruvate carboxylase is critical for non-small-cell lung cancer proliferation. , 2015, The Journal of clinical investigation.
[11] Can Alkan,et al. Activating mutations of STAT5B and STAT3 in lymphomas derived from γδ-T or NK cells , 2015, Nature Communications.
[12] B. Ebert,et al. Distinct effects of concomitant Jak2V617F expression and Tet2 loss in mice promote disease progression in myeloproliferative neoplasms. , 2015, Blood.
[13] W. Vainchenker,et al. TET2 loss, a rescue of JAK2V617F HSCs. , 2015, Blood.
[14] A. Iwama,et al. Loss of TET2 has dual roles in murine myeloproliferative neoplasms: disease sustainer and disease accelerator. , 2015, Blood.
[15] W. Xue,et al. Exome sequencing identifies somatic mutations of DDX3X in natural killer/T-cell lymphoma , 2014, Nature Genetics.
[16] Benjamin J. Raphael,et al. Pan-Cancer Network Analysis Identifies Combinations of Rare Somatic Mutations across Pathways and Protein Complexes , 2014, Nature Genetics.
[17] T. Rausch,et al. The activating STAT5B N642H mutation is a common abnormality in pediatric T-cell acute lymphoblastic leukemia and confers a higher risk of relapse , 2014, Haematologica.
[18] Heather L. Mulder,et al. Targetable kinase-activating lesions in Ph-like acute lymphoblastic leukemia. , 2014, The New England journal of medicine.
[19] J. Ochocki,et al. Fructose-1, 6-bisphosphatase opposes renal carcinoma progression , 2014, Nature.
[20] N. Harris,et al. A targeted mutational landscape of angioimmunoblastic T-cell lymphoma. , 2012, Blood.
[21] R. Eisenman,et al. An overview of MYC and its interactome. , 2014, Cold Spring Harbor perspectives in medicine.
[22] M. Stratton,et al. Clinical and biological implications of driver mutations in myelodysplastic syndromes. , 2013, Blood.
[23] David Haussler,et al. Discovering causal pathways linking genomic events to transcriptional states using Tied Diffusion Through Interacting Events (TieDIE) , 2013, Bioinform..
[24] Benjamin J. Raphael,et al. Mutational landscape and significance across 12 major cancer types , 2013, Nature.
[25] C. Dang. MYC, metabolism, cell growth, and tumorigenesis. , 2013, Cold Spring Harbor perspectives in medicine.
[26] J. Turkson,et al. Therapeutic modulators of STAT signalling for human diseases , 2013, Nature Reviews Drug Discovery.
[27] Benjamin J. Raphael,et al. Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia. , 2013, The New England journal of medicine.
[28] Y. Xia,et al. First‐line combination of gemcitabine, oxaliplatin, and L‐asparaginase (GELOX) followed by involved‐field radiation therapy for patients with stage IE/IIE extranodal natural killer/T‐cell lymphoma , 2013, Cancer.
[29] Michael R. Green,et al. Metabolic signatures uncover distinct targets in molecular subsets of diffuse large B cell lymphoma. , 2012, Cancer cell.
[30] S. Mustjoki,et al. STAT3 mutations unify the pathogenesis of chronic lymphoproliferative disorders of NK cells and T-cell large granular lymphocyte leukemia. , 2012, Blood.
[31] David A. Orlando,et al. Revisiting Global Gene Expression Analysis , 2012, Cell.
[32] S. Mustjoki,et al. Somatic STAT3 mutations in large granular lymphocytic leukemia. , 2012, The New England journal of medicine.
[33] A. Trumpp,et al. Genome-wide mapping of Myc binding and gene regulation in serum-stimulated fibroblasts , 2011, Oncogene.
[34] Hongkai Ji,et al. Cell-Type Independent MYC Target Genes Reveal a Primordial Signature Involved in Biomass Accumulation , 2011, PloS one.
[35] Raul Rabadan,et al. Analysis of the Coding Genome of Diffuse Large B-Cell Lymphoma , 2011, Nature Genetics.
[36] J. Zucman‐Rossi,et al. Somatic mutations activating STAT3 in human inflammatory hepatocellular adenomas , 2011, The Journal of experimental medicine.
[37] R. Suzuki. Treatment of advanced extranodal NK/T cell lymphoma, nasal-type and aggressive NK-cell leukemia , 2010, International journal of hematology.
[38] W. Huber,et al. which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. MAnorm: a robust model for quantitative comparison of ChIP-Seq data sets , 2011 .
[39] Xuegong Zhang,et al. DEGseq: an R package for identifying differentially expressed genes from RNA-seq data , 2010, Bioinform..
[40] Hua Yu,et al. STATs in cancer inflammation and immunity: a leading role for STAT3 , 2009, Nature Reviews Cancer.
[41] M. Samanta,et al. Epstein–Barr virus-encoded small RNA induces IL-10 through RIG-I-mediated IRF-3 signaling , 2008, Oncogene.
[42] Brad T. Sherman,et al. Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources , 2008, Nature Protocols.
[43] Adam A. Margolin,et al. NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth , 2006, Proceedings of the National Academy of Sciences.
[44] Bianca Sperl,et al. Stattic: a small-molecule inhibitor of STAT3 activation and dimerization. , 2006, Chemistry & biology.
[45] D.Y. Lee,et al. Aggressive NK‐cell leukaemia associated with reactive haemophagocytic syndrome , 2006, Clinical and experimental dermatology.
[46] H. Tagawa,et al. Genome‐wide array‐based comparative genomic hybridization of natural killer cell lymphoma/leukemia: Different genomic alteration patterns of aggressive NK‐cell leukemia and extranodal Nk/T‐cell lymphoma, nasal type , 2005, Genes, chromosomes & cancer.
[47] Pablo Tamayo,et al. Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[48] K. Kawa,et al. Aggressive natural killer-cell leukemia revisited: large granular lymphocyte leukemia of cytotoxic NK cells , 2004, Leukemia.
[49] T. Naoe,et al. Epstein–Barr virus‐encoded poly(A)− RNA supports Burkitt's lymphoma growth through interleukin‐10 induction , 2000, The EMBO journal.
[50] Y. Matsuo,et al. A novel natural killer cell line (KHYG-1) from a patient with aggressive natural killer cell leukemia carrying a p53 point mutation , 2000, Leukemia.
[51] T. Hirano,et al. Stat3 Is Required for the Gp130-mediated Full Activation of the C-myc Gene , 1999 .
[52] J. Chan,et al. Nonnasal lymphoma expressing the natural killer cell marker CD56: a clinicopathologic study of 49 cases of an uncommon aggressive neoplasm. , 1997, Blood.
[53] J. Gong,et al. Characterization of a human cell line (NK-92) with phenotypical and functional characteristics of activated natural killer cells. , 1994, Leukemia.