Design of the optical phantom of tissue for photodynamic therapy research

An optical phantom of tissue has been devised to simulate the optical properties of typical tissues for research in photodynamic therapy (PDT). The phantom consists of a scatterer (polystyrene-divinylbenzene microspheres) and an absorber (india ink) in distilled water. A set of relevant data for the microscopic optical properties and macroscopic optical parameter of the phantom was found. The results obtained approximate the optical properties of typical tissues. This optical phantom may duplicate the spatial variation of the radiant energy fluence of typical human tissues at 630 nm wavelength in PDT.