Current reprogramming methods to generate high-quality iPSCs
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Young Joo Cha | Pierre Leblanc | Chun-Hyung Kim | Jeffrey Schweitzer | Kwang-Soo Kim | Kwang-Soo Kim | J. Schweitzer | Y. Cha | P. Leblanc | Chun-Hyung Kim
[1] Jungho Kim,et al. Pyruvate kinase isozyme type M2 (PKM2) interacts and cooperates with Oct-4 in regulating transcription. , 2008, The international journal of biochemistry & cell biology.
[2] S. Yagi,et al. Oocyte-specific linker histone H1foo is an epigenomic modulator that decondenses chromatin and impairs pluripotency , 2012, Epigenetics.
[3] Anna-Katerina Hadjantonakis,et al. Distinct sequential cell behaviours direct primitive endoderm formation in the mouse blastocyst , 2008, Development.
[4] J. Utikal,et al. Induced Pluripotent Stem Cells Generated Without Viral Integration , 2008, Science.
[5] R. Blelloch,et al. miR-294/miR-302 promotes proliferation, suppresses G1-S restriction point, and inhibits ESC differentiation through separable mechanisms. , 2013, Cell reports.
[6] Yoshifumi Kawamura,et al. Direct reprogramming of somatic cells is promoted by maternal transcription factor Glis1 , 2011, Nature.
[7] J. Miyazaki,et al. Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells , 2000, Nature Genetics.
[8] A. Chan,et al. Development of single mouse blastomeres into blastocysts, outgrowths and the establishment of embryonic stem cells. , 2008, Reproduction.
[9] J. Ecker,et al. ERRs Mediate a Metabolic Switch Required for Somatic Cell Reprogramming to Pluripotency. , 2015, Cell stem cell.
[10] Jonghwan Kim,et al. Transcription Elongation Factor Tcea3 Regulates the Pluripotent Differentiation Potential of Mouse Embryonic Stem Cells Via the Lefty1‐Nodal‐Smad2 Pathway , 2013, Stem cells.
[11] M. Fritsch,et al. Dynamic Changes in Histone H3 Phosphoacetylation during Early Embryonic Stem Cell Differentiation Are Directly Mediated by Mitogen- and Stress-activated Protein Kinase 1 via Activation of MAPK Pathways* , 2006, Journal of Biological Chemistry.
[12] M. Murakami,et al. The Homeoprotein Nanog Is Required for Maintenance of Pluripotency in Mouse Epiblast and ES Cells , 2003, Cell.
[13] Stuart H. Orkin,et al. A protein interaction network for pluripotency of embryonic stem cells , 2006, Nature.
[14] Hans R Schöler,et al. Regulatory circuits underlying pluripotency and reprogramming. , 2009, Trends in pharmacological sciences.
[15] R. Jaenisch,et al. Induced Pluripotent Stem Cells Meet Genome Editing. , 2016, Cell stem cell.
[16] S. Baylin,et al. Butyrate Greatly Enhances Derivation of Human Induced Pluripotent Stem Cells by Promoting Epigenetic Remodeling and the Expression of Pluripotency‐Associated Genes , 2010, Stem cells.
[17] X. Tian,et al. Functionality and transduction condition evaluation of recombinant Klf4 for improved reprogramming of iPS cells. , 2011, Cellular reprogramming.
[18] K. Eto,et al. Ten years of induced pluripotency: from basic mechanisms to therapeutic applications , 2016, Development.
[19] Robert Lanza,et al. Generation of human induced pluripotent stem cells by direct delivery of reprogramming proteins. , 2009, Cell stem cell.
[20] George Q. Daley,et al. Reprogramming of human somatic cells to pluripotency with defined factors , 2008, Nature.
[21] Johanna E. Goldmann,et al. Efficient Reprogramming of Human Fibroblasts and Blood-Derived Endothelial Progenitor Cells Using Nonmodified RNA for Reprogramming and Immune Evasion. , 2015, Human gene therapy.
[22] A. Rizzino,et al. DNA microarray analyses of genes regulated during the differentiation of embryonic stem cells , 2000, Molecular reproduction and development.
[23] Robert L. Judson,et al. Embryonic stem cell–specific microRNAs promote induced pluripotency , 2009, Nature Biotechnology.
[24] Naoki Nishishita,et al. Efficient generation of transgene-free human induced pluripotent stem cells (iPSCs) by temperature-sensitive Sendai virus vectors , 2011, Proceedings of the National Academy of Sciences.
[25] P. Savatier,et al. Krüppel-like transcription factors and control of pluripotency , 2010, BMC Biology.
[26] A. Rizzino,et al. Small Increases in the Level of Sox2 Trigger the Differentiation of Mouse Embryonic Stem Cells , 2008, Stem cells.
[27] D. Melton,et al. "Stemness": Transcriptional Profiling of Embryonic and Adult Stem Cells , 2002, Science.
[28] Rudolf Jaenisch,et al. Parkinson's Disease Patient-Derived Induced Pluripotent Stem Cells Free of Viral Reprogramming Factors , 2009, Cell.
[29] Marius Wernig,et al. c-Myc is dispensable for direct reprogramming of mouse fibroblasts. , 2008, Cell stem cell.
[30] F. Gage,et al. Evaluating cell reprogramming, differentiation and conversion technologies in neuroscience , 2016, Nature Reviews Neuroscience.
[31] H. Schöler,et al. A combined chemical and genetic approach for the generation of induced pluripotent stem cells. , 2008, Cell stem cell.
[32] H. Schöler,et al. Stem cell pluripotency and transcription factor Oct4 , 2002, Cell Research.
[33] T. Ichisaka,et al. Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors , 2007, Cell.
[34] H. Schöler,et al. Oct-4 transcription factor is differentially expressed in the mouse embryo during establishment of the first two extraembryonic cell lineages involved in implantation. , 1994, Developmental biology.
[35] Megan Scudellari. How iPS cells changed the world , 2016, Nature.
[36] W. L. Ruzzo,et al. MicroRNA Discovery and Profiling in Human Embryonic Stem Cells by Deep Sequencing of Small RNA Libraries , 2008, Stem cells.
[37] Wenjun Guo,et al. Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds , 2008, Nature Biotechnology.
[38] E. Wanker,et al. HIF1α Modulates Cell Fate Reprogramming Through Early Glycolytic Shift and Upregulation of PDK1–3 and PKM2 , 2014, Stem cells.
[39] H. Schöler,et al. Developmental cell biology: Regulatory networks in embryo-derived pluripotent stem cells , 2005, Nature Reviews Molecular Cell Biology.
[40] Y. Yan,et al. Hhex and scl function in parallel to regulate early endothelial and blood differentiation in zebrafish. , 2000, Development.
[41] J. Renard,et al. Cloned rabbits produced by nuclear transfer from adult somatic cells , 2002, Nature Biotechnology.
[42] N. Nakatsuji,et al. Role of SOX2 in maintaining pluripotency of human embryonic stem cells , 2010, Genes to cells : devoted to molecular & cellular mechanisms.
[43] P. Kolatkar,et al. The SOX transcription factors as key players in pluripotent stem cells. , 2014, Stem cells and development.
[44] M. Hasegawa,et al. Efficient induction of transgene-free human pluripotent stem cells using a vector based on Sendai virus, an RNA virus that does not integrate into the host genome , 2009, Proceedings of the Japan Academy. Series B, Physical and biological sciences.
[45] Deepak M. Gupta,et al. A nonviral minicircle vector for deriving human iPS cells , 2010, Nature Methods.
[46] W. Wong,et al. Activation of Innate Immunity Is Required for Efficient Nuclear Reprogramming , 2012, Cell.
[47] Peter G Schultz,et al. Reprogramming of murine fibroblasts to induced pluripotent stem cells with chemical complementation of Klf4 , 2009, Proceedings of the National Academy of Sciences.
[48] Gwangil Kim,et al. Lefty1 and lefty2 control the balance between self-renewal and pluripotent differentiation of mouse embryonic stem cells. , 2014, Stem cells and development.
[49] V. Kim,et al. Regulation of microRNA biogenesis , 2014, Nature Reviews Molecular Cell Biology.
[50] J. Nichols,et al. Oct4 and LIF/Stat3 additively induce Krüppel factors to sustain embryonic stem cell self-renewal. , 2009, Cell stem cell.
[51] S. Dalton,et al. LIF/STAT3 controls ES cell self-renewal and pluripotency by a Myc-dependent mechanism , 2005, Development.
[52] Sandy L. Klemm,et al. Single-Cell Expression Analyses during Cellular Reprogramming Reveal an Early Stochastic and a Late Hierarchic Phase , 2012, Cell.
[53] G. Daley,et al. Metabolic regulation in pluripotent stem cells during reprogramming and self-renewal. , 2012, Cell stem cell.
[54] Shinsuke Yuasa,et al. Generation of induced pluripotent stem cells from human terminally differentiated circulating T cells. , 2010, Cell stem cell.
[55] Dajiang Qin,et al. Role of Lef1 in sustaining self-renewal in mouse embryonic stem cells. , 2010, Journal of genetics and genomics = Yi chuan xue bao.
[56] Hans R. Schöler,et al. Establishment of totipotency does not depend on Oct4A , 2013, Nature Cell Biology.
[57] S. Futaki,et al. Delivery of Macromolecules Using Arginine-Rich Cell-Penetrating Peptides: Ways to Overcome Endosomal Entrapment , 2009, The AAPS Journal.
[58] G. Daley,et al. Lin28: A MicroRNA Regulator with a Macro Role , 2010, Cell.
[59] W. Cui,et al. Sox2, a key factor in the regulation of pluripotency and neural differentiation. , 2014, World journal of stem cells.
[60] H. Ng,et al. KLF4 and PBX1 Directly Regulate NANOG Expression in Human Embryonic Stem Cells , 2009, Stem cells.
[61] L. Guarente,et al. Metabolic control of primed human pluripotent stem cell fate and function by the miR-200c–SIRT2 axis , 2017, Nature Cell Biology.
[62] Mark J. Murphy,et al. c-Myc controls the balance between hematopoietic stem cell self-renewal and differentiation. , 2004, Genes & development.
[63] Y Tsunoda,et al. Eight calves cloned from somatic cells of a single adult. , 1998, Science.
[64] Andre Terzic,et al. Mitochondrial oxidative metabolism is required for the cardiac differentiation of stem cells , 2007, Nature Clinical Practice Cardiovascular Medicine.
[65] Carl O. Pabo,et al. Cellular uptake of the tat protein from human immunodeficiency virus , 1988, Cell.
[66] J. Nolta,et al. Concise Review: MicroRNA Function in Multipotent Mesenchymal Stromal Cells , 2014, Stem cells.
[67] M. Son,et al. Nicotinamide Overcomes Pluripotency Deficits and Reprogramming Barriers , 2013, Stem cells.
[68] Yutao Du,et al. Low incidence of DNA sequence variation in human induced pluripotent stem cells generated by nonintegrating plasmid expression. , 2012, Cell stem cell.
[69] Merlin Crossley,et al. Krüppel-like transcription factors: a functional family. , 2008, The international journal of biochemistry & cell biology.
[70] H. Schöler,et al. Generation of Human‐Induced Pluripotent Stem Cells in the Absence of Exogenous Sox2 , 2009, Stem cells.
[71] C. Zeiss,et al. A null mutation of Hhex results in abnormal cardiac development, defective vasculogenesis and elevated Vegfa levels , 2004, Development.
[72] G. Orphanides,et al. Molecular basis for the recognition of phosphorylated and phosphoacetylated histone h3 by 14-3-3. , 2005, Molecular cell.
[73] Sheng Ding,et al. Generation of rat and human induced pluripotent stem cells by combining genetic reprogramming and chemical inhibitors. , 2009, Cell stem cell.
[74] R. Lafyatis,et al. Generation of Transgene‐Free Lung Disease‐Specific Human Induced Pluripotent Stem Cells Using a Single Excisable Lentiviral Stem Cell Cassette , 2010, Stem cells.
[75] William Ritchie,et al. Genome-wide characterization of the routes to pluripotency , 2014, Nature.
[76] H. Deng,et al. A XEN-like State Bridges Somatic Cells to Pluripotency during Chemical Reprogramming , 2015, Cell.
[77] Takashi Aoi,et al. Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts , 2008, Nature Biotechnology.
[78] S. Yamanaka,et al. The Use of Induced Pluripotent Stem Cells in Drug Development , 2011, Clinical pharmacology and therapeutics.
[79] Mo Li,et al. Looking to the future following 10 years of induced pluripotent stem cell technologies , 2016, Nature Protocols.
[80] B. Lim,et al. Oocyte Factors Suppress Mitochondrial Polynucleotide Phosphorylase to Remodel the Metabolome and Enhance Reprogramming. , 2015, Cell reports.
[81] Wenjun Guo,et al. Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2 , 2008, Nature Biotechnology.
[82] D. Beach,et al. A high glycolytic flux supports the proliferative potential of murine embryonic stem cells. , 2006, Antioxidants & redox signaling.
[83] Ron Shamir,et al. Comprehensive MicroRNA Profiling Reveals a Unique Human Embryonic Stem Cell Signature Dominated by a Single Seed Sequence , 2008, Stem cells.
[84] J. Lenormand,et al. Targeted release of transcription factors for human cell reprogramming by ZEBRA cell-penetrating peptide. , 2017, International journal of pharmaceutics.
[85] P. Robson,et al. Sall4 regulates distinct transcription circuitries in different blastocyst-derived stem cell lineages. , 2008, Cell stem cell.
[86] Grace X. Y. Zheng,et al. A Latent Pro-Survival Function for the Mir-290-295 Cluster in Mouse Embryonic Stem Cells , 2011, PLoS genetics.
[87] Hyun-Jai Cho,et al. Induction of pluripotent stem cells from adult somatic cells by protein-based reprogramming without genetic manipulation. , 2010, Blood.
[88] Juan Carlos Izpisua Belmonte,et al. The metabolome of induced pluripotent stem cells reveals metabolic changes occurring in somatic cell reprogramming , 2011, Cell Research.
[89] Ryan E. Mills,et al. Increased Genomic Integrity of an Improved Protein‐Based Mouse Induced Pluripotent Stem Cell Method Compared With Current Viral‐Induced Strategies , 2014, Stem cells translational medicine.
[90] J. Nichols,et al. Functional Expression Cloning of Nanog, a Pluripotency Sustaining Factor in Embryonic Stem Cells , 2003, Cell.
[91] Zhonghui Zhang,et al. MicroRNA-302/367 Cluster Governs hESC Self-Renewal by Dually Regulating Cell Cycle and Apoptosis Pathways , 2015, Stem cell reports.
[92] Jialiang Liang,et al. A mesenchymal-to-epithelial transition initiates and is required for the nuclear reprogramming of mouse fibroblasts. , 2010, Cell stem cell.
[93] M. Blasco,et al. The Ink4/Arf locus is a barrier for iPS cell reprogramming , 2009, Nature.
[94] Andre Terzic,et al. Somatic oxidative bioenergetics transitions into pluripotency-dependent glycolysis to facilitate nuclear reprogramming. , 2011, Cell metabolism.
[95] H. Deng,et al. Pluripotent Stem Cells Induced from Mouse Somatic Cells by Small-Molecule Compounds , 2013, Science.
[96] J. Gurdon,et al. Mechanisms of nuclear reprogramming by eggs and oocytes: a deterministic process? , 2011, Nature Reviews Molecular Cell Biology.
[97] M. Thier,et al. Cellular Reprogramming Employing Recombinant Sox2 Protein , 2012, Stem cells international.
[98] Sheng Ding,et al. Induction of pluripotent stem cells from mouse embryonic fibroblasts by Oct4 and Klf4 with small-molecule compounds. , 2008, Cell stem cell.
[99] H. Redl,et al. Vitamin C enhances the generation of mouse and human induced pluripotent stem cells. , 2010, Cell stem cell.
[100] Jing Chen,et al. BMPs functionally replace Klf4 and support efficient reprogramming of mouse fibroblasts by Oct4 alone , 2011, Cell Research.
[101] Philip R. Cohen,et al. MSK1 is required for CREB phosphorylation in response to mitogens in mouse embryonic stem cells , 2000, FEBS letters.
[102] P. Collas,et al. Induction of dedifferentiation, genomewide transcriptional programming, and epigenetic reprogramming by extracts of carcinoma and embryonic stem cells. , 2005, Molecular biology of the cell.
[103] Tohru Kimura,et al. Dppa3 expression is critical for generation of fully reprogrammed iPS cells and maintenance of Dlk1-Dio3 imprinting , 2015, Nature Communications.
[104] Martin H. Teicher,et al. Human Autologous iPSC-Derived Dopaminergic Progenitors Restore Motor Function in Parkinson's Disease Models. , 2019, The Journal of clinical investigation.
[105] Mike J. Mason,et al. Role of the Murine Reprogramming Factors in the Induction of Pluripotency , 2009, Cell.
[106] J. Miyazaki,et al. Klf4 Cooperates with Oct3/4 and Sox2 To Activate the Lefty1 Core Promoter in Embryonic Stem Cells , 2006, Molecular and Cellular Biology.
[107] R. Eisenman,et al. N-myc is essential during neurogenesis for the rapid expansion of progenitor cell populations and the inhibition of neuronal differentiation. , 2002, Genes & development.
[108] H. Rohrer,et al. Prox1 Regulates the Notch1-Mediated Inhibition of Neurogenesis , 2010, PLoS biology.
[109] X. Chen,et al. The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells , 2006, Nature Genetics.
[110] S. Saladi,et al. ATP Dependent Chromatin Remodeling Enzymes in Embryonic Stem Cells , 2010, Stem Cell Reviews and Reports.
[111] Shinya Yamanaka,et al. Promotion of direct reprogramming by transformation-deficient Myc , 2010, Proceedings of the National Academy of Sciences.
[112] S. Yamanaka,et al. Premature Termination of Reprogramming In Vivo Leads to Cancer Development through Altered Epigenetic Regulation , 2014, Cell.
[113] Alexander Meissner,et al. Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA. , 2010, Cell stem cell.
[114] Jason P Awe,et al. Identifying candidate oocyte reprogramming factors using cross-species global transcriptional analysis. , 2013, Cellular reprogramming.
[115] C. Allis,et al. Synergistic coupling of histone H3 phosphorylation and acetylation in response to epidermal growth factor stimulation. , 2000, Molecular cell.
[116] P. Burridge,et al. MicroRNA‐302 Increases Reprogramming Efficiency via Repression of NR2F2 , 2013, Stem cells.
[117] Xin Li,et al. A comparison of non-integrating reprogramming methods , 2014, Nature Biotechnology.
[118] S. Yamanaka,et al. Maturation, not initiation, is the major roadblock during reprogramming toward pluripotency from human fibroblasts , 2013, Proceedings of the National Academy of Sciences.
[119] Sheng Zhong,et al. A core Klf circuitry regulates self-renewal of embryonic stem cells , 2008, Nature Cell Biology.
[120] G. Daley,et al. The promise of induced pluripotent stem cells in research and therapy , 2012, Nature.
[121] Hideyuki Okano,et al. Variation in the safety of induced pluripotent stem cell lines , 2009, Nature Biotechnology.
[122] Dong Wook Han,et al. Generation of induced pluripotent stem cells using recombinant proteins. , 2009, Cell stem cell.
[123] E. Moss,et al. Two genetic circuits repress the Caenorhabditis elegans heterochronic gene lin-28 after translation initiation. , 2002, Developmental biology.
[124] Athanasios Stergiopoulos,et al. Nuclear receptor NR5A2 controls neural stem cell fate decisions during development , 2016, Nature Communications.
[125] Alice E. Chen,et al. Reprogramming within hours following nuclear transfer into mouse but not human zygotes. , 2011, Nature communications.
[126] G. Wahl,et al. Linking the p53 tumor suppressor pathway to somatic cell reprogramming , 2009, Nature.
[127] H. Sugiyama,et al. A synthetic small molecule for rapid induction of multiple pluripotency genes in mouse embryonic fibroblasts , 2012, Scientific Reports.
[128] I. Wilmut,et al. Rapid induction of pluripotency genes after exposure of human somatic cells to mouse ES cell extracts. , 2008, Experimental cell research.
[129] J. Seelig,et al. The cationic cell-penetrating peptide CPP(TAT) derived from the HIV-1 protein TAT is rapidly transported into living fibroblasts: optical, biophysical, and metabolic evidence. , 2005, Biochemistry.
[130] Megan F. Cole,et al. Core Transcriptional Regulatory Circuitry in Human Embryonic Stem Cells , 2005, Cell.
[131] R. Lovell-Badge,et al. Multipotent cell lineages in early mouse development depend on SOX2 function. , 2003, Genes & development.
[132] Hidenori Akutsu,et al. A small-molecule inhibitor of tgf-Beta signaling replaces sox2 in reprogramming by inducing nanog. , 2009, Cell stem cell.
[133] Maikun Teng,et al. MicroRNA Cluster 302–367 Enhances Somatic Cell Reprogramming by Accelerating a Mesenchymal-to-Epithelial Transition* , 2011, The Journal of Biological Chemistry.
[134] T. Elsdale,et al. Sexually Mature Individuals of Xenopus laevis from the Transplantation of Single Somatic Nuclei , 1958, Nature.
[135] Ayellet V. Segrè,et al. The Lin28/let-7 Axis Regulates Glucose Metabolism , 2011, Cell.
[136] Robert L. Judson,et al. microRNA control of mouse and human pluripotent stem cell behavior. , 2013, Annual review of cell and developmental biology.
[137] R. Deberardinis,et al. The biology of cancer: metabolic reprogramming fuels cell growth and proliferation. , 2008, Cell metabolism.
[138] S. Moon,et al. Human embryonic stem cells express a unique set of microRNAs. , 2004, Developmental biology.
[139] Yang Yang,et al. Kruppel-like Factor 4 (Klf4) Prevents Embryonic Stem (ES) Cell Differentiation by Regulating Nanog Gene Expression* , 2010, The Journal of Biological Chemistry.
[140] M. Destrempes,et al. Production of goats by somatic cell nuclear transfer , 1999, Nature Biotechnology.
[141] Wenbo Zhou,et al. Adenoviral Gene Delivery Can Reprogram Human Fibroblasts to Induced Pluripotent Stem Cells , 2009, Stem cells.
[142] P. Krebsbach,et al. DPPA5 Supports Pluripotency and Reprogramming by Regulating NANOG Turnover , 2016, Stem cells.
[143] Hong Wang,et al. Oocyte-Specific Homeobox 1, Obox1, Facilitates Reprogramming by Promoting Mesenchymal-to-Epithelial Transition and Mitigating Cell Hyperproliferation , 2017, Stem cell reports.
[144] Robert L. Judson,et al. Multiple targets of miR-302 and miR-372 promote reprogramming of human fibroblasts to induced pluripotent stem cells , 2011, Nature Biotechnology.
[145] R. Stewart,et al. Human Induced Pluripotent Stem Cells Free of Vector and Transgene Sequences , 2009, Science.
[146] J. Utikal,et al. Immortalization eliminates a roadblock during cellular reprogramming into iPS cells , 2009, Nature.
[147] M. Kuo,et al. Function and regulation of let-7 family microRNAs. , 2012, MicroRNA.
[148] Christian A. Ross,et al. LIN28 Regulates Stem Cell Metabolism and Conversion to Primed Pluripotency. , 2016, Cell stem cell.
[149] Kejin Hu. Vectorology and factor delivery in induced pluripotent stem cell reprogramming. , 2014, Stem cells and development.
[150] Ryan D. Morin,et al. Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. , 2008, Genome research.
[151] R. Guérois,et al. Structural basis for the interaction of Asf1 with histone H3 and its functional implications , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[152] E. Moss,et al. Conservation of the heterochronic regulator Lin-28, its developmental expression and microRNA complementary sites. , 2003, Developmental biology.
[153] K. Hochedlinger,et al. Chromatin dynamics during cellular reprogramming , 2013, Nature.
[154] R. Stewart,et al. Induced Pluripotent Stem Cell Lines Derived from Human Somatic Cells , 2007, Science.
[155] C. Bradshaw,et al. Hierarchical Molecular Events Driven by Oocyte-Specific Factors Lead to Rapid and Extensive Reprogramming , 2014, Molecular cell.
[156] Ariberto Fassati,et al. HIV infection of non-dividing cells: a divisive problem , 2006, Retrovirology.
[157] Stuart Thomson,et al. MSK2 and MSK1 mediate the mitogen‐ and stress‐induced phosphorylation of histone H3 and HMG‐14 , 2003, The EMBO journal.
[158] Kavitha T. Kuppusamy,et al. Hypoxia-inducible factors have distinct and stage-specific roles during reprogramming of human cells to pluripotency. , 2014, Cell stem cell.
[159] F. Real,et al. Interaction between Hhex and SOX13 Modulates Wnt/TCF Activity , 2009, The Journal of Biological Chemistry.
[160] Kazuki Takahashi,et al. Effects of downregulating GLIS1 transcript on preimplantation development and gene expression of bovine embryos , 2015, The Journal of reproduction and development.
[161] P. Knoepfler,et al. Inducing iPSCs to escape the dish. , 2011, Cell stem cell.
[162] Jeroen S. van Zon,et al. Direct cell reprogramming is a stochastic process amenable to acceleration , 2009, Nature.
[163] Qi Zhou,et al. Brief Report: Combined Chemical Treatment Enables Oct4‐Induced Reprogramming from Mouse Embryonic Fibroblasts , 2011, Stem cells.
[164] S. Orkin,et al. An Extended Transcriptional Network for Pluripotency of Embryonic Stem Cells , 2008, Cell.
[165] Maurizio Zuccotti,et al. Full-term development of mice from enucleated oocytes injected with cumulus cell nuclei , 1998, Nature.
[166] J. I. Izpisúa Belmonte,et al. Mitochondrial regulation in pluripotent stem cells. , 2013, Cell metabolism.
[167] Z. Ge,et al. Characterization of LEF1 High Expression and Novel Mutations in Adult Acute Lymphoblastic Leukemia , 2015, PloS one.
[168] Chun-Hyung Kim,et al. Purification of functional reprogramming factors in mammalian cell using FLAG -Tag. , 2017, Biochemical and biophysical research communications.
[169] Yasuko Matsumura,et al. A more efficient method to generate integration-free human iPS cells , 2011, Nature Methods.
[170] Weiqi Zhang,et al. Generation of iPSCs from mouse fibroblasts with a single gene, Oct4, and small molecules , 2011, Cell Research.
[171] V. Ambros,et al. The Cold Shock Domain Protein LIN-28 Controls Developmental Timing in C. elegans and Is Regulated by the lin-4 RNA , 1997, Cell.
[172] Herbert Schulz,et al. Novel STAT3 Target Genes Exert Distinct Roles in the Inhibition of Mesoderm and Endoderm Differentiation in Cooperation with Nanog , 2009, Stem cells.
[173] Mitsugu Sekimoto,et al. Reprogramming of mouse and human cells to pluripotency using mature microRNAs. , 2011, Cell stem cell.
[174] M. Pirity,et al. Generation of mouse induced pluripotent stem cells by protein transduction. , 2014, Tissue engineering. Part C, Methods.
[175] S. Yamanaka,et al. Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors , 2006, Cell.
[176] Shinya Yamanaka,et al. Generation of Mouse Induced Pluripotent Stem Cells Without Viral Vectors , 2008, Science.
[177] H. Ruohola-Baker,et al. Metabolic RemodeLIN of Pluripotency. , 2016, Cell stem cell.
[178] Mudit Gupta,et al. Highly efficient miRNA-mediated reprogramming of mouse and human somatic cells to pluripotency. , 2011, Cell stem cell.
[179] J. Nichols,et al. Nanog safeguards pluripotency and mediates germline development , 2007, Nature.
[180] Philippe Collas,et al. Reprogramming fibroblasts to express T-cell functions using cell extracts , 2002, Nature Biotechnology.
[181] H. Schöler,et al. Molecular Obstacles to Clinical Translation of iPSCs. , 2016, Cell stem cell.
[182] S. Kliewer,et al. Orphan Nuclear Receptor LRH-1 Is Required To Maintain Oct4 Expression at the Epiblast Stage of Embryonic Development , 2005, Molecular and Cellular Biology.
[183] M. Thier,et al. Exploring refined conditions for reprogramming cells by recombinant Oct4 protein. , 2010, The International journal of developmental biology.
[184] Ge Guo,et al. Nanog Is the Gateway to the Pluripotent Ground State , 2009, Cell.
[185] A. Miller,et al. Gene transfer by retrovirus vectors occurs only in cells that are actively replicating at the time of infection , 1990, Molecular and cellular biology.
[186] Kristi A. Hohenstein,et al. Regulation of Self‐Renewal and Pluripotency by Sox2 in Human Embryonic Stem Cells , 2008, Stem cells.
[187] Jie Chen,et al. Critical regulation of miR-200/ZEB2 pathway in Oct4/Sox2-induced mesenchymal-to-epithelial transition and induced pluripotent stem cell generation , 2013, Proceedings of the National Academy of Sciences.
[188] S. Yamanaka,et al. A decade of transcription factor-mediated reprogramming to pluripotency , 2016, Nature Reviews Molecular Cell Biology.
[189] Li Zhong,et al. Murine embryonic stem cell differentiation is promoted by SOCS-3 and inhibited by the zinc finger transcription factor Klf4. , 2005, Blood.
[190] P. Knoepfler. Why myc? An unexpected ingredient in the stem cell cocktail. , 2008, Cell stem cell.
[191] Yuriy L Orlov,et al. The nuclear receptor Nr5a2 can replace Oct4 in the reprogramming of murine somatic cells to pluripotent cells. , 2010, Cell stem cell.
[192] Kwang-Soo Kim,et al. Obox4 regulates the expression of histone family genes and promotes differentiation of mouse embryonic stem cells , 2010, FEBS letters.
[193] W. Walther,et al. Viral Vectors for Gene Transfer , 2012, Drugs.
[194] I. Wilmut,et al. "Viable Offspring Derived from Fetal and Adult Mammalian Cells" (1997), by Ian Wilmut et al. , 2014 .
[195] J. Wong,et al. Reprogramming of somatic cells via TAT-mediated protein transduction of recombinant factors. , 2012, Biomaterials.
[196] Kit T. Rodolfa,et al. Sox17 promotes differentiation in mouse embryonic stem cells by directly regulating extraembryonic gene expression and indirectly antagonizing self-renewal. , 2010, Genes & development.
[197] H. Schöler,et al. Differential expression of the Oct-4 transcription factor during mouse germ cell differentiation , 1998, Mechanisms of Development.
[198] N. D. Clarke,et al. Integration of External Signaling Pathways with the Core Transcriptional Network in Embryonic Stem Cells , 2008, Cell.
[199] H. Schöler,et al. Formation of Pluripotent Stem Cells in the Mammalian Embryo Depends on the POU Transcription Factor Oct4 , 1998, Cell.
[200] Sheng Ding,et al. Reprogramming of human primary somatic cells by OCT4 and chemical compounds. , 2010, Cell stem cell.
[201] Hoon-Chul Kang,et al. Direct Reprogramming of Rat Neural Precursor Cells and Fibroblasts into Pluripotent Stem Cells , 2010, PloS one.
[202] Zhonghan Li,et al. Small RNA-mediated regulation of iPS cell generation , 2011, The EMBO journal.
[203] D. Bredt,et al. Tat protein from human immunodeficiency virus forms a metal-linked dimer. , 1988, Science.
[204] Yifan Dai,et al. Cloned pigs produced by nuclear transfer from adult somatic cells , 2000, Nature.
[205] Juan Carlos Izpisua Belmonte,et al. A High Proliferation Rate Is Required for Cell Reprogramming and Maintenance of Human Embryonic Stem Cell Identity , 2011, Current Biology.
[206] Jennifer Nichols,et al. Promotion of Reprogramming to Ground State Pluripotency by Signal Inhibition , 2008, PLoS biology.