Evaluating the mechanistic evidence and key data gaps in assessing the potential carcinogenicity of carbon nanotubes and nanofibers in humans
暂无分享,去创建一个
Kent E. Pinkerton | Peter Møller | Bice Fubini | Eileen D. Kuempel | Yasuo Morimoto | Agnes B. Kane | Norihiro Kobayashi | R. Vermeulen | P. Møller | M. Jaurand | A. Kane | K. Pinkerton | B. Fubini | Y. Morimoto | L. Sargent | E. Kuempel | Norihiro Kobayashi | Roel C. H. Vermeulen | Marie-Claude Jaurand | Linda M. Sargent
[1] Hiroyuki Tsuda,et al. Multiwalled carbon nanotubes intratracheally instilled into the rat lung induce development of pleural malignant mesothelioma and lung tumors , 2016, Cancer science.
[2] A. Shvedova,et al. Fibrosis biomarkers in workers exposed to MWCNTs. , 2016, Toxicology and applied pharmacology.
[3] Naveena Yanamala,et al. Integrated Analysis of Dysregulated ncRNA and mRNA Expression Profiles in Humans Exposed to Carbon Nanotubes , 2016, PloS one.
[4] D. Richardson,et al. Air Pollution and Pulmonary Tuberculosis: A Nested Case–Control Study among Members of a Northern California Health Plan , 2016, Environmental health perspectives.
[5] S. Redick,et al. Multipolar mitosis and aneuploidy after chrysotile treatment: a consequence of abscission failure and cytokinesis regression , 2016, Oncotarget.
[6] I. Yu,et al. Multiwall Carbon Nanotube-Induced DNA Damage and Cytotoxicity in Male Human Peripheral Blood Lymphocytes , 2016, International journal of toxicology.
[7] W. McKinney,et al. mRNAs and miRNAs in whole blood associated with lung hyperplasia, fibrosis, and bronchiolo‐alveolar adenoma and adenocarcinoma after multi‐walled carbon nanotube inhalation exposure in mice , 2016, Journal of applied toxicology : JAT.
[8] M. Ema,et al. Long‐term retention of pristine multi‐walled carbon nanotubes in rat lungs after intratracheal instillation , 2015, Journal of applied toxicology : JAT.
[9] D. Lison,et al. Mechanisms of lung fibrosis induced by carbon nanotubes: towards an Adverse Outcome Pathway (AOP) , 2015, Particle and Fibre Toxicology.
[10] Andrew Williams,et al. Meta-analysis of transcriptomic responses as a means to identify pulmonary disease outcomes for engineered nanomaterials , 2015, Particle and Fibre Toxicology.
[11] John J. Wyrick,et al. Genomic approaches to DNA repair and mutagenesis. , 2015, DNA repair.
[12] Ivan Rusyn,et al. Key Characteristics of Carcinogens as a Basis for Organizing Data on Mechanisms of Carcinogenesis , 2015, Environmental health perspectives.
[13] M. Schubauer-Berigan,et al. Assessing the first wave of epidemiological studies of nanomaterial workers , 2015, Journal of Nanoparticle Research.
[14] Alberto Bianco,et al. Carbon Nanotube Degradation in Macrophages: Live Nanoscale Monitoring and Understanding of Biological Pathway. , 2015, ACS nano.
[15] Susana Cristobal,et al. Vascular toxicity of ultra-small TiO2 nanoparticles and single walled carbon nanotubes in vitro and in vivo. , 2015, Biomaterials.
[16] M. Judson,et al. How are cancer and connective tissue diseases related to sarcoidosis? , 2015, Current opinion in pulmonary medicine.
[17] T. Regad. Targeting RTK Signaling Pathways in Cancer , 2015, Cancers.
[18] I. Yu,et al. Evaluation of in vitro and in vivo genotoxicity of single-walled carbon nanotubes , 2015, Toxicology and industrial health.
[19] Jong Seong Lee,et al. Health surveillance study of workers who manufacture multi-walled carbon nanotubes , 2015, Nanotoxicology.
[20] F. Nesslany,et al. Lung inflammation and lack of genotoxicity in the comet and micronucleus assays of industrial multiwalled carbon nanotubes Graphistrength© C100 after a 90-day nose-only inhalation exposure of rats , 2015, Particle and Fibre Toxicology.
[21] M. Schubauer-Berigan,et al. Carbon Nanotube and Nanofiber Exposure Assessments: An Analysis of 14 Site Visits. , 2015, The Annals of occupational hygiene.
[22] William H. Bisson,et al. The potential for chemical mixtures from the environment to enable the cancer hallmark of sustained proliferative signalling. , 2015, Carcinogenesis.
[23] Vincent Castranova,et al. INHALATION EXPOSURE TO CARBON NANOTUBES (CNT) AND CARBON NANOFIBERS (CNF): METHODOLOGY AND DOSIMETRY , 2015, Journal of toxicology and environmental health. Part B, Critical reviews.
[24] M. Ohnishi,et al. Thirteen-week study of toxicity of fiber-like multi-walled carbon nanotubes with whole-body inhalation exposure in rats , 2015, Nanotoxicology.
[25] Meiying Wang,et al. NADPH Oxidase-Dependent NLRP3 Inflammasome Activation and its Important Role in Lung Fibrosis by Multiwalled Carbon Nanotubes. , 2015, Small.
[26] P. Borm,et al. Lung particle overload: old school –new insights? , 2015, Particle and Fibre Toxicology.
[27] Peter Morfeld,et al. Translational toxicology in setting occupational exposure limits for dusts and hazard classification – a critical evaluation of a recent approach to translate dust overload findings from rats to humans , 2015, Particle and Fibre Toxicology.
[28] S. Kutsev,et al. Genotoxicity of Single-Walled Carbon Nanotubes: In Vitro Study on Human Embryonic Fibroblast Cells , 2015, Bulletin of Experimental Biology and Medicine.
[29] Andrij Holian,et al. Extracellular HMGB1 regulates multi-walled carbon nanotube-induced inflammation in vivo , 2015, Nanotoxicology.
[30] Andrew Williams,et al. MWCNTs of different physicochemical properties cause similar inflammatory responses, but differences in transcriptional and histological markers of fibrosis in mouse lungs. , 2015, Toxicology and applied pharmacology.
[31] D. Iannazzo,et al. Toxicological assessment of multi-walled carbon nanotubes on A549 human lung epithelial cells. , 2015, Toxicology in vitro : an international journal published in association with BIBRA.
[32] G. Leitinger,et al. Carboxylated short single-walled carbon nanotubes but not plain and multi-walled short carbon nanotubes show in vitro genotoxicity. , 2015, Toxicological sciences : an official journal of the Society of Toxicology.
[33] Maria Dusinska,et al. Can the comet assay be used reliably to detect nanoparticle‐induced genotoxicity? , 2015, Environmental and molecular mutagenesis.
[34] Per Axel Clausen,et al. Characterization of genotoxic response to 15 multiwalled carbon nanotubes with variable physicochemical properties including surface functionalizations in the FE1‐Muta(TM) mouse lung epithelial cell line , 2015, Environmental and molecular mutagenesis.
[35] C. la Vecchia,et al. Sarcoidosis and cancer risk: systematic review and meta-analysis of observational studies. , 2015, Chest.
[36] Yi Cao,et al. Measurement of oxidative damage to DNA in nanomaterial exposed cells and animals , 2015, Environmental and molecular mutagenesis.
[37] J. Pauluhn,et al. Lung burdens and kinetics of multi-walled carbon nanotubes (Baytubes) are highly dependent on the disaggregation of aerosolized MWCNT , 2015, Nanotoxicology.
[38] J. Meng,et al. Carbon nanotubes activate macrophages into a M1/M2 mixed status: recruiting naïve macrophages and supporting angiogenesis. , 2015, ACS applied materials & interfaces.
[39] Liying Wang,et al. Gene expression profile of human lung epithelial cells chronically exposed to single-walled carbon nanotubes , 2015, Nanoscale Research Letters.
[40] A. Pandiri. Comparative Pathobiology of Environmentally Induced Lung Cancers in Humans and Rodents , 2015, Toxicologic pathology.
[41] J. Pauluhn. Derivation of occupational exposure levels (OELs) of Low-toxicity isometric biopersistent particles: how can the kinetic lung overload paradigm be used for improved inhalation toxicity study design and OEL-derivation? , 2014, Particle and Fibre Toxicology.
[42] D. Lison,et al. The alarmin IL-1α is a master cytokine in acute lung inflammation induced by silica micro- and nanoparticles , 2014, Particle and Fibre Toxicology.
[43] Jürgen Schnekenburger,et al. Pulmonary toxicity of nanomaterials: a critical comparison of published in vitro assays and in vivo inhalation or instillation studies. , 2014, Nanomedicine.
[44] L. Gaté,et al. Cytotoxicity and Genotoxicity of Panel of Single- and Multiwalled Carbon Nanotubes: In Vitro Effects on Normal Syrian Hamster Embryo and Immortalized V79 Hamster Lung Cells , 2014, Journal of toxicology.
[45] E. Zenteno,et al. Analysis of microRNA expression signatures in malignant pleural mesothelioma, pleural inflammation, and atypical mesothelial hyperplasia reveals common predictive tumorigenesis-related targets. , 2014, Experimental and molecular pathology.
[46] Kurt Straif,et al. Carcinogenicity of fluoro-edenite, silicon carbide fibres and whiskers, and carbon nanotubes. , 2014, The Lancet. Oncology.
[47] Yung-sung Cheng,et al. Carbon nanotubes size classification, characterization and nasal airway deposition , 2014, Inhalation toxicology.
[48] Heinrich Ernst,et al. The carcinogenic effect of various multi-walled carbon nanotubes (MWCNTs) after intraperitoneal injection in rats , 2014, Particle and Fibre Toxicology.
[49] Y. Shieh,et al. Radical scavenging efficiencies of modified and microwave-treated multiwalled carbon nanotubes , 2014 .
[50] V. Sherwood,et al. WNT Signaling: an Emerging Mediator of Cancer Cell Metabolism? , 2014, Molecular and Cellular Biology.
[51] N. Chatterjee,et al. Potential Toxicity of Differential Functionalized Multiwalled Carbon Nanotubes (MWCNT) in Human Cell Line (BEAS2B) and Caenorhabditis elegans , 2014, Journal of toxicology and environmental health. Part A.
[52] Steffen Loft,et al. Statistical analysis of comet assay results , 2014, Front. Genet..
[53] O. Raabe,et al. Instillation versus Inhalation of Multiwalled Carbon Nanotubes: Exposure-Related Health Effects, Clearance, and the Role of Particle Characteristics , 2014, ACS nano.
[54] I. Yu,et al. Single-Wall Carbon Nanotubes (SWCNT) Induce Cytotoxicity and Genotoxicity Produced by Reactive Oxygen Species (ROS) Generation in Phytohemagglutinin (PHA)-Stimulated Male Human Peripheral Blood Lymphocytes , 2014, Journal of toxicology and environmental health. Part A.
[55] Liying Wang,et al. Neoplastic-like transformation effect of single-walled and multi-walled carbon nanotubes compared to asbestos on human lung small airway epithelial cells , 2014, Nanotoxicology.
[56] N. Dharmasiri,et al. Carbon and clay nanoparticles induce minimal stress responses in gram negative bacteria and eukaryotic fish cells , 2014, Environmental toxicology.
[57] S. Bellucci,et al. Differences in Cytotoxic, Genotoxic, and Inflammatory Response of Bronchial and Alveolar Human Lung Epithelial Cells to Pristine and COOH-Functionalized Multiwalled Carbon Nanotubes , 2014, BioMed research international.
[58] M. Jaurand,et al. Quantification of short and long asbestos fibers to assess asbestos exposure: a review of fiber size toxicity , 2014, Environmental Health.
[59] Håkan Wallin,et al. DNA Damage Following Pulmonary Exposure by Instillation to Low Doses of Carbon Black (Printex 90) Nanoparticles in Mice , 2014, Environmental and molecular mutagenesis.
[60] Hongtao Yu,et al. DNA damage in human skin keratinocytes caused by multiwalled carbon nanotubes with carboxylate functionalization , 2014, Toxicology and industrial health.
[61] J. Kanno,et al. Size- and shape-dependent pleural translocation, deposition, fibrogenesis, and mesothelial proliferation by multiwalled carbon nanotubes , 2014, Cancer science.
[62] Liying Wang,et al. Role of H-Ras/ERK signaling in carbon nanotube-induced neoplastic-like transformation of human mesothelial cells , 2014, Front. Physiol..
[63] J. Guirouilh-Barbat,et al. Is homologous recombination really an error-free process? , 2014, Front. Genet..
[64] H. Iwahashi,et al. Intratracheal instillation of single-wall carbon nanotubes in the rat lung induces time-dependent changes in gene expression , 2014, Nanotoxicology.
[65] Gilles Patriarche,et al. Carbon nanotube translocation to distant organs after pulmonary exposure: insights from in situ (14)C-radiolabeling and tissue radioimaging. , 2014, ACS nano.
[66] A. Verma,et al. Single-walled carbon nanotubes induce cytotoxicity and DNA damage via reactive oxygen species in human hepatocarcinoma cells , 2014, In Vitro Cellular & Developmental Biology - Animal.
[67] Feng Yang,et al. Effect of multi-walled carbon nanotube surface modification on bioactivity in the C57BL/6 mouse model , 2014, Nanotoxicology.
[68] J. Pauluhn. The metrics of MWCNT-induced pulmonary inflammation are dependent on the selected testing regimen. , 2014, Regulatory toxicology and pharmacology : RTP.
[69] Yi Cao,et al. Vascular effects of multiwalled carbon nanotubes in dyslipidemic ApoE-/- mice and cultured endothelial cells. , 2014, Toxicological sciences : an official journal of the Society of Toxicology.
[70] P. Glazer,et al. Interplay between DNA repair and inflammation, and the link to cancer , 2014, Critical reviews in biochemistry and molecular biology.
[71] Jin Sik Kim,et al. In vivo genotoxicity evaluation of lung cells from Fischer 344 rats following 28 days of inhalation exposure to MWCNTs, plus 28 days and 90 days post-exposure , 2014, Inhalation toxicology.
[72] Jared M Brown,et al. IL-33 modulates chronic airway resistance changes induced by multi-walled carbon nanotubes , 2014, Inhalation toxicology.
[73] Albert Duschl,et al. The Significance and Insignificance of Carbon Nanotube-Induced Inflammation , 2014 .
[74] Maria João Silva,et al. Genotoxicity evaluation of nanosized titanium dioxide, synthetic amorphous silica and multi-walled carbon nanotubes in human lymphocytes. , 2014, Toxicology in vitro : an international journal published in association with BIBRA.
[75] P. Møller,et al. Pulmonary exposure to particles from diesel exhaust, urban dust or single-walled carbon nanotubes and oxidatively damaged DNA and vascular function in apoE-/- mice , 2014, Nanotoxicology.
[76] N. Wu,et al. IL-1R signalling is critical for regulation of multi-walled carbon nanotubes-induced acute lung inflammation in C57Bl/6 mice , 2014, Nanotoxicology.
[77] C. Dinu,et al. Genotoxicity of multi-walled carbon nanotubes at occupationally relevant doses , 2014, Particle and Fibre Toxicology.
[78] A. Elder,et al. Equivalent titanium dioxide nanoparticle deposition by intratracheal instillation and whole body inhalation: the effect of dose rate on acute respiratory tract inflammation , 2014, Particle and Fibre Toxicology.
[79] P. Møller,et al. Accumulation of lipids and oxidatively damaged DNA in hepatocytes exposed to particles. , 2014, Toxicology and applied pharmacology.
[80] V. Castranova,et al. Long-term effects of carbon containing engineered nanomaterials and asbestos in the lung: one year postexposure comparisons. , 2014, American journal of physiology. Lung cellular and molecular physiology.
[81] F. Chen,et al. Proteomic Analysis of Cellular Response Induced by Multi-Walled Carbon Nanotubes Exposure in A549 Cells , 2014, PloS one.
[82] W. McKinney,et al. Promotion of lung adenocarcinoma following inhalation exposure to multi-walled carbon nanotubes , 2014, Particle and Fibre Toxicology.
[83] Ann M. Janowski,et al. Inflammasomes in cancer: a double-edged sword , 2014, Protein & Cell.
[84] P. Avti,et al. Cytotoxicity, cytocompatibility, cell-labeling efficiency, and in vitro cellular magnetic resonance imaging of gadolinium-catalyzed single-walled carbon nanotubes. , 2013, Journal of biomedical materials research. Part A.
[85] Tatyana Chernova,et al. Pulmonary toxicity of carbon nanotubes and asbestos - similarities and differences. , 2013, Advanced drug delivery reviews.
[86] M. Cho,et al. Differential Toxic Responses Between Pristine and Functionalized Multiwall Nanotubes Involve Induction of Autophagy Accumulation in Murine Lung , 2013, Journal of toxicology and environmental health. Part A.
[87] Dongmei Wu,et al. Transcriptomic Analysis Reveals Novel Mechanistic Insight into Murine Biological Responses to Multi-Walled Carbon Nanotubes in Lungs and Cultured Lung Epithelial Cells , 2013, PloS one.
[88] Julia Catalán,et al. Genotoxicity of short single-wall and multi-wall carbon nanotubes in human bronchial epithelial and mesothelial cells in vitro. , 2013, Toxicology.
[89] Yong Qian,et al. System-based identification of toxicity pathways associated with multi-walled carbon nanotube-induced pathological responses. , 2013, Toxicology and applied pharmacology.
[90] M. Hayashi,et al. In vivo comet assay of multi‐walled carbon nanotubes using lung cells of rats intratracheally instilled , 2013, Journal of applied toxicology : JAT.
[91] O. Schärer. Nucleotide excision repair in eukaryotes. , 2013, Cold Spring Harbor perspectives in biology.
[92] Enkeleda Dervishi,et al. Raman spectroscopy analysis and mapping the biodistribution of inhaled carbon nanotubes in the lungs and blood of mice , 2013, Journal of applied toxicology : JAT.
[93] B. Sureka,et al. Radiological review of pleural tumors , 2013, Indian Journal of Radiology and Imaging.
[94] N. Suttorp,et al. NOD-Like Receptors in Lung Diseases , 2013, Front. Immunol..
[95] Xiaoxiao Cai,et al. Pharmacokinetics of CNT-based drug delivery systems. , 2013, Current drug metabolism.
[96] D Ghigo,et al. The Role of Iron Impurities in the Toxic Effects Exerted by Short Multiwalled Carbon Nanotubes (MWCNT) in Murine Alveolar Macrophages , 2013, Journal of toxicology and environmental health. Part A.
[97] Ker-Chau Li,et al. Focal amplification of HOXD-harboring chromosome region is implicated in multiple-walled carbon nanotubes-induced carcinogenicity. , 2013, Nano letters.
[98] M. Ema,et al. Genotoxicity evaluation for single‐walled carbon nanotubes in a battery of in vitro and in vivo assays , 2013, Journal of applied toxicology : JAT.
[99] S. Toyokuni,et al. Intraperitoneal administration of tangled multiwalled carbon nanotubes of 15 nm in diameter does not induce mesothelial carcinogenesis in rats , 2013, Pathology international.
[100] Judith Klein-Seetharaman,et al. Biodegradation of single-walled carbon nanotubes by eosinophil peroxidase. , 2013, Small.
[101] Vincent Castranova,et al. Extrapulmonary transport of MWCNT following inhalation exposure , 2013, Particle and Fibre Toxicology.
[102] Jo Anne Shatkin,et al. A multi-stakeholder perspective on the use of alternative test strategies for nanomaterial safety assessment. , 2013, ACS nano.
[103] V. Castranova,et al. Investigation of the Pulmonary Bioactivity of Double-Walled Carbon Nanotubes , 2013, Journal of toxicology and environmental health. Part A.
[104] J. Hong,et al. CCR5 plays an important role in resolving an inflammatory response to single‐walled carbon nanotubes , 2013, Journal of applied toxicology : JAT.
[105] W. McKinney,et al. Distribution and fibrotic response following inhalation exposure to multi-walled carbon nanotubes , 2013, Particle and Fibre Toxicology.
[106] B. van Ravenzwaay,et al. Additional histopathologic examination of the lungs from a 3-month inhalation toxicity study with multiwall carbon nanotubes in rats. , 2013, Toxicological sciences : an official journal of the Society of Toxicology.
[107] Ran Chen,et al. Comparison of nanotube-protein corona composition in cell culture media. , 2013, Small.
[108] M. Evans,et al. Human and methodological sources of variability in the measurement of urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine. , 2013, Antioxidants & redox signaling.
[109] K. Wakabayashi,et al. Genotoxicity of multi-walled carbon nanotubes in both in vitro and in vivo assay systems , 2013, Nanotoxicology.
[110] A. Nel,et al. Interlaboratory Evaluation of Rodent Pulmonary Responses to Engineered Nanomaterials: The NIEHS Nano GO Consortium , 2013, Environmental health perspectives.
[111] V. Castranova,et al. Systematic analysis of multiwalled carbon nanotube-induced cellular signaling and gene expression in human small airway epithelial cells. , 2013, Toxicological sciences : an official journal of the Society of Toxicology.
[112] Vicki Stone,et al. An in vitro assessment of panel of engineered nanomaterials using a human renal cell line: cytotoxicity, pro-inflammatory response, oxidative stress and genotoxicity , 2013, BMC Nephrology.
[113] C. Verschraegen,et al. New insights into understanding the mechanisms, pathogenesis, and management of malignant mesotheliomas. , 2013, The American journal of pathology.
[114] Jianhua Yang,et al. NF-κB and STAT3 signaling pathways collaboratively link inflammation to cancer , 2013, Protein & Cell.
[115] A. Barron,et al. Single-walled carbon nanotubes: differential genotoxic potential associated with physico-chemical properties , 2013, Nanotoxicology.
[116] N. Wu,et al. Purification and sidewall functionalization of multiwalled carbon nanotubes and resulting bioactivity in two macrophage models , 2013, Inhalation toxicology.
[117] Zongxi Li,et al. Surface charge and cellular processing of covalently functionalized multiwall carbon nanotubes determine pulmonary toxicity. , 2013, ACS nano.
[118] F. Galateau-Sallé,et al. Pleural plaques and the risk of pleural mesothelioma. , 2013, Journal of the National Cancer Institute.
[119] A. Stringaro,et al. Morphological transformation induced by multiwall carbon nanotubes on Balb/3T3 cell model as an in vitro end point of carcinogenic potential , 2013, Nanotoxicology.
[120] Steffen Loft,et al. Oxidatively damaged DNA in animals exposed to particles , 2013, Critical reviews in toxicology.
[121] F. Hennrich,et al. DNA damaging properties of single walled carbon nanotubes in human colon carcinoma cells , 2013, Nanotoxicology.
[122] Lang Tran,et al. Engineered nanomaterial risk. Lessons learnt from completed nanotoxicology studies: potential solutions to current and future challenges , 2013, Critical reviews in toxicology.
[123] S. Baylin. The cancer epigenome: its origins, contributions to tumorigenesis, and translational implications. , 2012, Proceedings of the American Thoracic Society.
[124] J. Kanno,et al. Multi‐walled carbon nanotubes translocate into the pleural cavity and induce visceral mesothelial proliferation in rats , 2012, Cancer science.
[125] Jeremy M. Gernand,et al. A Meta‐Analysis of Carbon Nanotube Pulmonary Toxicity Studies—How Physical Dimensions and Impurities Affect the Toxicity of Carbon Nanotubes , 2014, Risk analysis : an official publication of the Society for Risk Analysis.
[126] J. Haber,et al. Mutations arising during repair of chromosome breaks. , 2012, Annual review of genetics.
[127] H. Järventaus,et al. Induction of chromosomal aberrations by carbon nanotubes and titanium dioxide nanoparticles in human lymphocytes in vitro , 2012, Nanotoxicology.
[128] B. Rothen‐Rutishauser,et al. Differential effects of long and short carbon nanotubes on the gas-exchange region of the mouse lung , 2012, Nanotoxicology.
[129] J. Tschopp,et al. NLRP3 promotes inflammation‐induced skin cancer but is dispensable for asbestos‐induced mesothelioma , 2012, Immunology and cell biology.
[130] David H Phillips,et al. Inter-laboratory variation in DNA damage using a standard comet assay protocol. , 2012, Mutagenesis.
[131] K. Mizuno,et al. Pulmonary toxicity of well-dispersed single-wall carbon nanotubes after inhalation , 2012, Nanotoxicology.
[132] M. Hayashi,et al. In vivo genotoxicity study of single-wall carbon nanotubes using comet assay following intratracheal instillation in rats. , 2012, Regulatory toxicology and pharmacology : RTP.
[133] W. McKinney,et al. Multi-walled carbon nanotubes: sampling criteria and aerosol characterization , 2012, Inhalation toxicology.
[134] A. Borczuk. Neoplastic and nonneoplastic benign mass lesions of the lung. , 2012, Archives of pathology & laboratory medicine.
[135] A. Rao,et al. A carbon nanotube toxicity paradigm driven by mast cells and the IL-₃₃/ST₂ axis. , 2012, Small.
[136] R. Vassallo. Diffuse Lung Diseases in Cigarette Smokers , 2012, Seminars in Respiratory and Critical Care Medicine.
[137] G. Leitinger,et al. Combination of small size and carboxyl functionalisation causes cytotoxicity of short carbon nanotubes , 2012, Nanotoxicology.
[138] Yong Qian,et al. Multiwalled Carbon Nanotube-Induced Gene Signatures in the Mouse Lung: Potential Predictive Value for Human Lung Cancer Risk and Prognosis , 2012, Journal of toxicology and environmental health. Part A.
[139] Nianqiang Wu,et al. Acute pulmonary dose–responses to inhaled multi-walled carbon nanotubes , 2012, Nanotoxicology.
[140] K. Mizuno,et al. Pulmonary toxicity of well-dispersed multi-wall carbon nanotubes following inhalation and intratracheal instillation , 2012, Nanotoxicology.
[141] David B Warheit,et al. Ninety-day inhalation toxicity study with a vapor grown carbon nanofiber in rats. , 2012, Toxicological sciences : an official journal of the Society of Toxicology.
[142] Jong Seong Lee,et al. Persistent DNA damage measured by comet assay of Sprague Dawley rat lung cells after five days of inhalation exposure and 1 month post-exposure to dispersed multi-wall carbon nanotubes (MWCNTs) generated by new MWCNT aerosol generation system. , 2012, Toxicological sciences : an official journal of the Society of Toxicology.
[143] Adriele Prina-Mello,et al. The threshold length for fiber-induced acute pleural inflammation: shedding light on the early events in asbestos-induced mesothelioma. , 2012, Toxicological sciences : an official journal of the Society of Toxicology.
[144] S. Toyokuni,et al. Differences and similarities between carbon nanotubes and asbestos fibers during mesothelial carcinogenesis: Shedding light on fiber entry mechanism , 2012, Cancer science.
[145] K. Tracey,et al. Alarmins: awaiting a clinical response. , 2012, The Journal of clinical investigation.
[146] Craig A Poland,et al. Length-dependent pleural inflammation and parietal pleural responses after deposition of carbon nanotubes in the pulmonary airspaces of mice , 2012, Nanotoxicology.
[147] Vicki Stone,et al. An in vitro liver model - assessing oxidative stress and genotoxicity following exposure of hepatocytes to a panel of engineered nanomaterials , 2012, Particle and Fibre Toxicology.
[148] K. Machida,et al. Carcinogenicity evaluation for the application of carbon nanotubes as biomaterials in rasH2 mice , 2012, Scientific Reports.
[149] M. Schubauer-Berigan,et al. Occupational exposure assessment in carbon nanotube and nanofiber primary and secondary manufacturers. , 2012, The Annals of occupational hygiene.
[150] Eileen D Kuempel,et al. Risk assessment and risk management of nanomaterials in the workplace: translating research to practice. , 2012, The Annals of occupational hygiene.
[151] Y. Morimoto,et al. Pulmonary Toxicity of Well-Dispersed Single-Wall Carbon Nanotubes Following Intratracheal Instillation , 2012 .
[152] M. Ema,et al. Evaluation of genotoxicity of multi-walled carbon nanotubes in a battery of in vitro and in vivo assays. , 2012, Regulatory toxicology and pharmacology : RTP.
[153] K L Bunker,et al. Single-walled carbon nanotube-induced mitotic disruption. , 2012, Mutation research.
[154] Rachael M. Crist,et al. Autophagy and lysosomal dysfunction as emerging mechanisms of nanomaterial toxicity , 2012, Particle and Fibre Toxicology.
[155] Dirk E. Smith,et al. IL-33 mediates multi-walled carbon nanotube (MWCNT)-induced airway hyper-reactivity via the mobilization of innate helper cells in the lung , 2012, Nanotoxicology.
[156] Stefano Bellucci,et al. Multi‐walled carbon nanotubes induce cytotoxicity and genotoxicity in human lung epithelial cells , 2012, Journal of applied toxicology : JAT.
[157] J. K. Kundu,et al. Emerging avenues linking inflammation and cancer. , 2012, Free radical biology & medicine.
[158] J. Kanno,et al. Dose-dependent mesothelioma induction by intraperitoneal administration of multi-wall carbon nanotubes in p53 heterozygous mice , 2012, Cancer science.
[159] Zhiqing Lin,et al. Single-wall carbon nanotubes induce oxidative stress in rat aortic endothelial cells , 2012, Toxicology mechanisms and methods.
[160] Bengt Fadeel,et al. Factoring-in agglomeration of carbon nanotubes and nanofibers for better prediction of their toxicity versus asbestos , 2012, Particle and Fibre Toxicology.
[161] Yi Zhang,et al. Cell cycle regulation by carboxylated multiwalled carbon nanotubes through p53-independent induction of p21 under the control of the BMP signaling pathway. , 2012, Chemical research in toxicology.
[162] Bengt Fadeel,et al. Impaired Clearance and Enhanced Pulmonary Inflammatory/Fibrotic Response to Carbon Nanotubes in Myeloperoxidase-Deficient Mice , 2012, PloS one.
[163] G. Trinchieri. Cancer and inflammation: an old intuition with rapidly evolving new concepts. , 2012, Annual review of immunology.
[164] Douglas Hanahan,et al. Accessories to the Crime: Functions of Cells Recruited to the Tumor Microenvironment Prospects and Obstacles for Therapeutic Targeting of Function-enabling Stromal Cell Types , 2022 .
[165] C. Geraci,et al. Evaluation of the Potential Airborne Release of Carbon Nanofibers During the Preparation, Grinding, and Cutting of Epoxy-Based Nanocomposite Material , 2012, Journal of occupational and environmental hygiene.
[166] Alberto Mantovani,et al. Macrophage plasticity and polarization: in vivo veritas. , 2012, The Journal of clinical investigation.
[167] M. Karin,et al. NF‐κB and the link between inflammation and cancer , 2012, Immunological reviews.
[168] Dandan Song,et al. Vitamin E renders protection to PC12 cells against oxidative damage and apoptosis induced by single-walled carbon nanotubes. , 2012, Toxicology in vitro : an international journal published in association with BIBRA.
[169] C. Zouboulis,et al. Pro-inflammatory effects of different MWCNTs dispersions in p16INK4A-deficient telomerase-expressing human keratinocytes but not in human SV-40 immortalized sebocytes , 2012, Nanotoxicology.
[170] Ivana Fenoglio,et al. Thickness of multiwalled carbon nanotubes affects their lung toxicity. , 2012, Chemical research in toxicology.
[171] M. Molls,et al. Chronic Inflammation in Cancer Development , 2012, Front. Immun..
[172] Maumita Bandyopadhyay,et al. Multi-walled carbon nanotubes (MWCNT): induction of DNA damage in plant and mammalian cells. , 2011, Journal of hazardous materials.
[173] Federica Valentini,et al. Effects of single-wall carbon nanotubes in human cells of the oral cavity: geno-cytotoxic risk. , 2011, Toxicology in vitro : an international journal published in association with BIBRA.
[174] S. Baylin,et al. Oxidative damage targets complexes containing DNA methyltransferases, SIRT1, and polycomb members to promoter CpG Islands. , 2011, Cancer cell.
[175] S. Toyokuni,et al. Diameter and rigidity of multiwalled carbon nanotubes are critical factors in mesothelial injury and carcinogenesis , 2011, Proceedings of the National Academy of Sciences.
[176] K. Mizuno,et al. Evaluation of the genotoxic potential of single-wall carbon nanotubes by using a battery of in vitro and in vivo genotoxicity assays. , 2011, Regulatory toxicology and pharmacology : RTP.
[177] Douglas E. Evans,et al. Exposure and emissions monitoring during carbon nanofiber production--Part I: elemental carbon and iron-soot aerosols. , 2011, The Annals of occupational hygiene.
[178] K. Mizuno,et al. Pulmonary and systemic responses of highly pure and well-dispersed single-wall carbon nanotubes after intratracheal instillation in rats , 2011, Inhalation toxicology.
[179] Katsuhide Fujita,et al. Biopersistence of inhaled MWCNT in rat lungs in a 4-week well-characterized exposure , 2011, Inhalation toxicology.
[180] M. Karin,et al. Tumor promotion via injury- and death-induced inflammation. , 2011, Immunity.
[181] K. Kerr,et al. Causes of pulmonary granulomas: a retrospective study of 500 cases from seven countries , 2011, Journal of Clinical Pathology.
[182] Sangdun Choi,et al. Biological Toxicity and Inflammatory Response of Semi-Single-Walled Carbon Nanotubes , 2011, PloS one.
[183] Maurizio Prato,et al. Making carbon nanotubes biocompatible and biodegradable. , 2011, Chemical communications.
[184] A. Rao,et al. Multi-walled carbon nanotube instillation impairs pulmonary function in C57BL/6 mice , 2011, Particle and Fibre Toxicology.
[185] Per Axel Clausen,et al. Long, needle-like carbon nanotubes and asbestos activate the NLRP3 inflammasome through a similar mechanism. , 2011, ACS nano.
[186] Ivana Fenoglio,et al. Effect of chemical composition and state of the surface on the toxic response to high aspect ratio nanomaterials. , 2011, Nanomedicine.
[187] Vincent Castranova,et al. Pulmonary fibrotic response to aspiration of multi-walled carbon nanotubes , 2011, Particle and Fibre Toxicology.
[188] J. M. Nicholson,et al. Is carcinogenesis a form of speciation? , 2011, Cell cycle.
[189] Jin Sik Kim,et al. Aspect ratio has no effect on genotoxicity of multi-wall carbon nanotubes , 2011, Archives of Toxicology.
[190] Vincent Castranova,et al. Carbon nanotubes induce malignant transformation and tumorigenesis of human lung epithelial cells. , 2011, Nano letters.
[191] Federica Valentini,et al. Low doses of pristine and oxidized single-wall carbon nanotubes affect mammalian embryonic development. , 2011, ACS nano.
[192] A. Holian,et al. Potential Role of the Inflammasome-Derived Inflammatory Cytokines in Pulmonary Fibrosis , 2011, Pulmonary medicine.
[193] Antonio Nunes,et al. Length-dependent retention of carbon nanotubes in the pleural space of mice initiates sustained inflammation and progressive fibrosis on the parietal pleura. , 2011, The American journal of pathology.
[194] M. Schubauer-Berigan,et al. Exposure Control Strategies in the Carbonaceous Nanomaterial Industry , 2011, Journal of occupational and environmental medicine.
[195] A. Pant,et al. Multi-walled carbon nanotubes induce oxidative stress and apoptosis in human lung cancer cell line-A549 , 2011, Nanotoxicology.
[196] Sandro Santucci,et al. Effects of single and multi walled carbon nanotubes on macrophages: cyto and genotoxicity and electron microscopy. , 2011, Mutation research.
[197] R. Hurt,et al. A 3-dimensional in vitro model of epithelioid granulomas induced by high aspect ratio nanomaterials , 2011, Particle and Fibre Toxicology.
[198] M. Kwak,et al. Cell growth inhibition and apoptosis by SDS-solubilized single-walled carbon nanotubes in normal rat kidney epithelial cells , 2011, Archives of pharmacal research.
[199] A. Kane,et al. Non-Neoplastic and Neoplastic Pleural Endpoints Following Fiber Exposure , 2011, Journal of toxicology and environmental health. Part B, Critical reviews.
[200] Karl T. Kelsey,et al. Pulmonary Endpoints (Lung Carcinomas and Asbestosis) Following Inhalation Exposure to Asbestos , 2011, Journal of toxicology and environmental health. Part B, Critical reviews.
[201] Nicklas Raun Jacobsen,et al. Mutation spectrum in FE1‐MUTATMMouse lung epithelial cells exposed to nanoparticulate carbon black , 2011, Environmental and molecular mutagenesis.
[202] A. Rao,et al. Novel murine model of chronic granulomatous lung inflammation elicited by carbon nanotubes. , 2011, American journal of respiratory cell and molecular biology.
[203] J. Hong,et al. A single intratracheal instillation of single-walled carbon nanotubes induced early lung fibrosis and subchronic tissue damage in mice , 2011, Archives of Toxicology.
[204] Jun Yang,et al. Cytotoxic and genotoxic effects of multi-wall carbon nanotubes on human umbilical vein endothelial cells in vitro. , 2011, Mutation research.
[205] V. Castranova,et al. Genotoxicity of carbon nanofibers: are they potentially more or less dangerous than carbon nanotubes or asbestos? , 2011, Toxicology and applied pharmacology.
[206] D. Hanahan,et al. Hallmarks of Cancer: The Next Generation , 2011, Cell.
[207] Bengt Fadeel,et al. Toxicology of engineered nanomaterials: focus on biocompatibility, biodistribution and biodegradation. , 2011, Biochimica et biophysica acta.
[208] S. Barni,et al. Comparative pulmonary toxicity assessment of pristine and functionalized multi-walled carbon nanotubes intratracheally instilled in rats: morphohistochemical evaluations. , 2011, Histology and histopathology.
[209] Peter Wick,et al. A comparison of acute and long-term effects of industrial multiwalled carbon nanotubes on human lung and immune cells in vitro. , 2011, Toxicology letters.
[210] L. Cena,et al. Characterization and Control of Airborne Particles Emitted During Production of Epoxy/Carbon Nanotube Nanocomposites , 2011, Journal of occupational and environmental hygiene.
[211] Debra L Laskin,et al. Macrophages and tissue injury: agents of defense or destruction? , 2011, Annual review of pharmacology and toxicology.
[212] J. Schlager,et al. Comparative study of the clastogenicity of functionalized and nonfunctionalized multiwalled carbon nanotubes in bone marrow cells of Swiss‐Webster mice , 2010, Environmental toxicology.
[213] Shigehisa Endoh,et al. Biological response and morphological assessment of individually dispersed multi-wall carbon nanotubes in the lung after intratracheal instillation in rats. , 2010, Toxicology.
[214] Mara Ghiazza,et al. Physico-chemical features of engineered nanoparticles relevant to their toxicity , 2010, Nanotoxicology.
[215] C. Santeufemio,et al. Characterization of Exposures To Nanoscale Particles and Fibers During Solid Core Drilling of Hybrid Carbon Nanotube Advanced Composites , 2010, International journal of occupational and environmental health.
[216] Andreas Czich,et al. Collaborative study on fifteen compounds in the rat-liver Comet assay integrated into 2- and 4-week repeat-dose studies. , 2010, Mutation research.
[217] D. Gregoratto,et al. Modelling particle retention in the alveolar–interstitial region of the human lungs , 2010, Journal of radiological protection : official journal of the Society for Radiological Protection.
[218] Maren Schneider,et al. Reactive oxygen species as mediators of membrane-dependent signaling induced by ultrafine particles. , 2010, Free radical biology & medicine.
[219] G. Ramesh,et al. Multiwalled carbon nanotubes activate NF-κB and AP-1 signaling pathways to induce apoptosis in rat lung epithelial cells , 2010, Apoptosis.
[220] D. Wallace,et al. Bacterial lipopolysaccharide enhances PDGF signaling and pulmonary fibrosis in rats exposed to carbon nanotubes. , 2010, American journal of respiratory cell and molecular biology.
[221] Emmanuel Flahaut,et al. Carbon nanotubes induce inflammation but decrease the production of reactive oxygen species in lung. , 2010, Toxicology.
[222] Xinyuan Liu,et al. Biodurability of Single-Walled Carbon Nanotubes Depends on Surface Functionalization. , 2010, Carbon.
[223] Helinor J Johnston,et al. A critical review of the biological mechanisms underlying the in vivo and in vitro toxicity of carbon nanotubes: The contribution of physico-chemical characteristics , 2010, Nanotoxicology.
[224] V. Himabindu,et al. Translocation and extra pulmonary toxicities of multi wall carbon nanotubes in rats , 2010, Toxicology mechanisms and methods.
[225] Kevin H. Dunn,et al. Aerosol Monitoring during Carbon Nanofiber Production: Mobile Direct-Reading Sampling , 2010, The Annals of occupational hygiene.
[226] Andrea Magrini,et al. Carbon nanotubes induce oxidative DNA damage in RAW 264.7 cells , 2010, Environmental and molecular mutagenesis.
[227] S. Fukushima,et al. Genotoxicity and Cytotoxicity of Multi‐wall Carbon Nanotubes in Cultured Chinese Hamster Lung Cells in Comparison with Chrysotile A Fibers , 2010, Journal of occupational health.
[228] Vincent Castranova,et al. Distribution and persistence of pleural penetrations by multi-walled carbon nanotubes , 2010, Particle and Fibre Toxicology.
[229] J. Bonner. Nanoparticles as a potential cause of pleural and interstitial lung disease. , 2010, Proceedings of the American Thoracic Society.
[230] Judith Klein-Seetharaman,et al. Carbon nanotubes degraded by neutrophil myeloperoxidase induce less pulmonary inflammation. , 2010, Nature nanotechnology.
[231] P. Møller,et al. Oxidative Damage to DNA and Lipids as Biomarkers of Exposure to Air Pollution , 2010, Environmental health perspectives.
[232] Annia Galano,et al. Influence of Point Defects on the Free-Radical Scavenging Capability of Single-Walled Carbon Nanotubes , 2010 .
[233] H. Takano,et al. Repeated pulmonary exposure to single-walled carbon nanotubes exacerbates allergic inflammation of the airway: Possible role of oxidative stress. , 2010, Free radical biology & medicine.
[234] Craig A. Poland,et al. Asbestos, carbon nanotubes and the pleural mesothelium: a review of the hypothesis regarding the role of long fibre retention in the parietal pleura, inflammation and mesothelioma , 2010, Particle and Fibre Toxicology.
[235] M. Karin,et al. Immunity, Inflammation, and Cancer , 2010, Cell.
[236] G. Bae,et al. Exposure assessment of carbon nanotube manufacturing workplaces , 2010, Inhalation toxicology.
[237] Nianqiang Wu,et al. Mouse pulmonary dose- and time course-responses induced by exposure to multi-walled carbon nanotubes. , 2010, Toxicology.
[238] A. Galano. Carbon nanotubes: promising agents against free radicals. , 2010, Nanoscale.
[239] S. Mukhopadhyay,et al. Clinically occult interstitial fibrosis in smokers: classification and significance of a surprisingly common finding in lobectomy specimens. , 2010, Human pathology.
[240] C. Varga,et al. Carbon nanotubes induce granulomas but not mesotheliomas. , 2010, In vivo.
[241] Henri Szwarc,et al. In vivo behavior of large doses of ultrashort and full-length single-walled carbon nanotubes after oral and intraperitoneal administration to Swiss mice. , 2010, ACS nano.
[242] Yasuo Yoshioka,et al. Carbon Nanotubes Elicit DNA Damage and Inflammatory Response Relative to Their Size and Shape , 2010, Inflammation.
[243] Rodney Andrews,et al. Acute pulmonary response of mice to multi-wall carbon nanotubes , 2010, Inhalation toxicology.
[244] Liying Wang,et al. Direct Fibrogenic Effects of Dispersed Single-Walled Carbon Nanotubes on Human Lung Fibroblasts , 2010, Journal of toxicology and environmental health. Part A.
[245] N. Heintz,et al. Asbestos, lung cancers, and mesotheliomas: from molecular approaches to targeting tumor survival pathways. , 2010, American journal of respiratory cell and molecular biology.
[246] G. Joksiċ,et al. Using carbon nanotubes to induce micronuclei and double strand breaks of the DNA in human cells , 2010, Nanotechnology.
[247] N. Wu,et al. Particle length-dependent titanium dioxide nanomaterials toxicity and bioactivity , 2009, Particle and Fibre Toxicology.
[248] Heidrun Ellinger-Ziegelbauer,et al. Pulmonary toxicity of multi-walled carbon nanotubes (Baytubes) relative to alpha-quartz following a single 6h inhalation exposure of rats and a 3 months post-exposure period. , 2009, Toxicology.
[249] B. van Ravenzwaay,et al. Inhalation toxicity of multiwall carbon nanotubes in rats exposed for 3 months. , 2009, Toxicological sciences : an official journal of the Society of Toxicology.
[250] A. Cuschieri,et al. Influence of purity and surface oxidation on cytotoxicity of multiwalled carbon nanotubes with human neuroblastoma cells. , 2009, Nanomedicine : nanotechnology, biology, and medicine.
[251] I. McInnes,et al. IL-33 Amplifies the Polarization of Alternatively Activated Macrophages That Contribute to Airway Inflammation1 , 2009, The Journal of Immunology.
[252] M L Kashon,et al. Induction of aneuploidy by single‐walled carbon nanotubes , 2009, Environmental and molecular mutagenesis.
[253] Jeffery A. Steevens,et al. Potential for Occupational Exposure to Engineered Carbon-Based Nanomaterials in Environmental Laboratory Studies , 2009, Environmental health perspectives.
[254] M. Andersen,et al. Inhaled Carbon Nanotubes Reach the Sub-Pleural Tissue in Mice , 2009, Nature nanotechnology.
[255] Agnes B Kane,et al. Biopersistence and potential adverse health impacts of fibrous nanomaterials: what have we learned from asbestos? , 2009, Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology.
[256] Amy K Madl,et al. Health effects of inhaled engineered and incidental nanoparticles , 2009, Critical reviews in toxicology.
[257] François Huaux,et al. Absence of carcinogenic response to multiwall carbon nanotubes in a 2-year bioassay in the peritoneal cavity of the rat. , 2009, Toxicological sciences : an official journal of the Society of Toxicology.
[258] J. Kong,et al. Characterization and evaluation of nanoparticle release during the synthesis of single-walled and multiwalled carbon nanotubes by chemical vapor deposition. , 2009, Environmental science & technology.
[259] Alberto Mantovani,et al. Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability. , 2009, Carcinogenesis.
[260] S W Burchiel,et al. Mechanisms for how inhaled multiwalled carbon nanotubes suppress systemic immune function in mice. , 2009, Nature nanotechnology.
[261] M. Jaurand,et al. Particle and Fibre Toxicology Mesothelioma: Do Asbestos and Carbon Nanotubes Pose the Same Health Risk? , 2022 .
[262] Kyunghee Choi,et al. Pro-inflammatory and potential allergic responses resulting from B cell activation in mice treated with multi-walled carbon nanotubes by intratracheal instillation. , 2009, Toxicology.
[263] U. Wirnitzer,et al. Studies on the in vitro genotoxicity of baytubes, agglomerates of engineered multi-walled carbon-nanotubes (MWCNT). , 2009, Toxicology letters.
[264] Minnamari Vippola,et al. Genotoxicity of nanomaterials: DNA damage and micronuclei induced by carbon nanotubes and graphite nanofibres in human bronchial epithelial cells in vitro. , 2009, Toxicology letters.
[265] Brian A Wong,et al. Inhaled multiwalled carbon nanotubes potentiate airway fibrosis in murine allergic asthma. , 2009, American journal of respiratory cell and molecular biology.
[266] James M Tour,et al. Antioxidant single-walled carbon nanotubes. , 2009, Journal of the American Chemical Society.
[267] Stefano Bellucci,et al. Multi-walled carbon nanotubes: Lack of mutagenic activity in the bacterial reverse mutation assay. , 2009, Toxicology letters.
[268] Shyam Sundhar Bale,et al. Tubulin encapsulation of carbon nanotubes into functional hybrid assemblies. , 2009, Small.
[269] Akihiko Hirose,et al. Induction of mesothelioma by a single intrascrotal administration of multi-wall carbon nanotube in intact male Fischer 344 rats. , 2009, The Journal of toxicological sciences.
[270] Nicklas Raun Jacobsen,et al. Lung inflammation and genotoxicity following pulmonary exposure to nanoparticles in ApoE-/- mice , 2009, Particle and Fibre Toxicology.
[271] Chao Liu,et al. Comparative study of cytotoxicity, oxidative stress and genotoxicity induced by four typical nanomaterials: the role of particle size, shape and composition , 2009, Journal of applied toxicology : JAT.
[272] P. Hanawalt,et al. Transcription-coupled DNA repair: two decades of progress and surprises , 2008, Nature Reviews Molecular Cell Biology.
[273] D. Elgrabli,et al. Induction of apoptosis and absence of inflammation in rat lung after intratracheal instillation of multiwalled carbon nanotubes. , 2008, Toxicology.
[274] Steffen Loft,et al. Oxidatively Damaged DNA in Rats Exposed by Oral Gavage to C60 Fullerenes and Single-Walled Carbon Nanotubes , 2008, Environmental health perspectives.
[275] P. Baron,et al. Inhalation vs. aspiration of single-walled carbon nanotubes in C57BL/6 mice: inflammation, fibrosis, oxidative stress, and mutagenesis. , 2008, American journal of physiology. Lung cellular and molecular physiology.
[276] Ya‐Ping Sun,et al. Reversible accumulation of PEGylated single-walled carbon nanotubes in the mammalian nucleus. , 2008, ACS nano.
[277] H. Karlsson,et al. Copper oxide nanoparticles are highly toxic: a comparison between metal oxide nanoparticles and carbon nanotubes. , 2008, Chemical research in toxicology.
[278] E. Cameron,et al. Oncogene-induced senescence: An essential role for Runx , 2008, Cell cycle.
[279] J. Nagy,et al. Structural defects play a major role in the acute lung toxicity of multiwall carbon nanotubes: physicochemical aspects. , 2008, Chemical research in toxicology.
[280] Antonio Marcomini,et al. Genotoxicity, cytotoxicity, and reactive oxygen species induced by single‐walled carbon nanotubes and C60 fullerenes in the FE1‐Muta™Mouse lung epithelial cells , 2008, Environmental and molecular mutagenesis.
[281] Craig A. Poland,et al. Carbon nanotubes introduced into the abdominal cavity of mice show asbestos-like pathogenicity in a pilot study. , 2008, Nature nanotechnology.
[282] Mark D. Hoover,et al. Raw Single-Wall Carbon Nanotubes Induce Oxidative Stress and Activate MAPKs, AP-1, NF-κB, and Akt in Normal and Malignant Human Mesothelial Cells , 2008, Environmental health perspectives.
[283] J. Tschopp,et al. Innate Immune Activation Through Nalp3 Inflammasome Sensing of Asbestos and Silica , 2008, Science.
[284] Steffen Loft,et al. Variation in assessment of oxidatively damaged DNA in mononuclear blood cells by the comet assay with visual scoring. , 2008, Mutagenesis.
[285] Brian L. Wardle,et al. Particle exposure levels during CVD growth and subsequent handling of vertically-aligned carbon nanotube films , 2008 .
[286] K. Straif,et al. Use of mechanistic data in IARC evaluations , 2008, Environmental and molecular mutagenesis.
[287] G. Ludewig,et al. Mutagenicity of 3-methylcholanthrene, pcb3, and 4-oh-pcb3 in the lung of transgenic bigblue rats. , 2008, Environmental toxicology and pharmacology.
[288] J. Kanno,et al. Induction of mesothelioma in p53+/- mouse by intraperitoneal application of multi-wall carbon nanotube. , 2008, The Journal of toxicological sciences.
[289] François Huaux,et al. Clastogenic and aneugenic effects of multi-wall carbon nanotubes in epithelial cells. , 2008, Carcinogenesis.
[290] Cheng-Chung Chou,et al. Single-walled carbon nanotubes can induce pulmonary injury in mouse model. , 2008, Nano letters.
[291] G. Sancini,et al. Translocation pathways for inhaled asbestos fibers , 2008, Environmental health : a global access science source.
[292] Vincent Castranova,et al. A biocompatible medium for nanoparticle dispersion , 2008 .
[293] Romeo Bernini,et al. Cytotoxicity Investigation on Cultured Human Blood Cells Treated with Single-Wall Carbon Nanotubes , 2008, Sensors.
[294] Gwi-Nam Bae,et al. Monitoring Multiwalled Carbon Nanotube Exposure in Carbon Nanotube Research Facility , 2008 .
[295] J. Dement,et al. An epidemiological study of the role of chrysotile asbestos fibre dimensions in determining respiratory disease risk in exposed workers , 2007, Occupational and Environmental Medicine.
[296] Liming Dai,et al. DNA damage induced by multiwalled carbon nanotubes in mouse embryonic stem cells. , 2007, Nano letters.
[297] Vincent Castranova,et al. Single-walled Carbon Nanotubes: Geno- and Cytotoxic Effects in Lung Fibroblast V79 Cells , 2007, Journal of toxicology and environmental health. Part A.
[298] Scott W Burchiel,et al. Pulmonary and systemic immune response to inhaled multiwalled carbon nanotubes. , 2007, Toxicological sciences : an official journal of the Society of Toxicology.
[299] Mark D. Hoover,et al. Identification and Characterization of Potential Sources of Worker Exposure to Carbon Nanofibers During Polymer Composite Laboratory Operations , 2007, Journal of occupational and environmental hygiene.
[300] Michael E. Barsan,et al. NIOSH pocket guide to chemical hazards , 2007 .
[301] Nicklas Raun Jacobsen,et al. Increased mutant frequency by carbon black, but not quartz, in the lacZ and cII transgenes of muta™mouse lung epithelial cells , 2007, Environmental and molecular mutagenesis.
[302] V. Castranova,et al. Vitamin E deficiency enhances pulmonary inflammatory response and oxidative stress induced by single-walled carbon nanotubes in C57BL/6 mice. , 2007, Toxicology and applied pharmacology.
[303] S. Sarkar,et al. Analysis of stress responsive genes induced by single-walled carbon nanotubes in BJ Foreskin cells. , 2007, Journal of nanoscience and nanotechnology.
[304] Roel P F Schins,et al. Genotoxicity of Poorly Soluble Particles , 2007, Inhalation toxicology.
[305] Xiaogang Qu,et al. Carbon nanotubes selective destabilization of duplex and triplex DNA and inducing B–A transition in solution , 2006, Nucleic acids research.
[306] Roel P F Schins,et al. Neutrophils and respiratory tract DNA damage and mutagenesis: a review. , 2006, Mutagenesis.
[307] Ivana Fenoglio,et al. Reactivity of carbon nanotubes: free radical generation or scavenging activity? , 2006, Free radical biology & medicine.
[308] Kurt Straif,et al. Carcinogenicity of carbon black, titanium dioxide, and talc. , 2006, The Lancet. Oncology.
[309] N. Bottini,et al. Multi-walled carbon nanotubes induce T lymphocyte apoptosis. , 2006, Toxicology letters.
[310] A. Maynard,et al. Airborne Nanostructured Particles and Occupational Health , 2005 .
[311] Robert Gelein,et al. Effects of subchronically inhaled carbon black in three species. I. Retention kinetics, lung inflammation, and histopathology. , 2005, Toxicological sciences : an official journal of the Society of Toxicology.
[312] M. Serrano,et al. The Senescent Side of Tumor Suppression , 2005, Cell cycle.
[313] P. Baron,et al. Unusual inflammatory and fibrogenic pulmonary responses to single-walled carbon nanotubes in mice. , 2005, American journal of physiology. Lung cellular and molecular physiology.
[314] Julie W. Fitzpatrick,et al. Principles for characterizing the potential human health effects from exposure to nanomaterials: elements of a screening strategy , 2005, Particle and Fibre Toxicology.
[315] J. Nagy,et al. Respiratory toxicity of multi-wall carbon nanotubes. , 2005, Toxicology and applied pharmacology.
[316] I. Lambert,et al. Detailed review of transgenic rodent mutation assays. , 2005, Mutation research.
[317] G. Oberdörster,et al. Nanotoxicology: An Emerging Discipline Evolving from Studies of Ultrafine Particles , 2005, Environmental health perspectives.
[318] E. Tagaya,et al. Ultrafine carbon black particles stimulate proliferation of human airway epithelium via EGF receptor-mediated signaling pathway. , 2004, American journal of physiology. Lung cellular and molecular physiology.
[319] P. Kvale,et al. Cancer and interstitial lung disease , 2004, Current opinion in pulmonary medicine.
[320] G. Raghu,et al. The epidemiology of interstitial lung disease and its association with lung cancer , 2004, British Journal of Cancer.
[321] Catrin Albrecht,et al. Inhaled particles and lung cancer, part B: Paradigms and risk assessment , 2004, International journal of cancer.
[322] K. Donaldson,et al. Increased inflammation and altered macrophage chemotactic responses caused by two ultrafine particle types , 2004, Occupational and Environmental Medicine.
[323] P. Baron,et al. Exposure to Carbon Nanotube Material: Aerosol Release During the Handling of Unrefined Single-Walled Carbon Nanotube Material , 2004, Journal of toxicology and environmental health. Part A.
[324] J. James,et al. Pulmonary toxicity of single-wall carbon nanotubes in mice 7 and 90 days after intratracheal instillation. , 2003, Toxicological sciences : an official journal of the Society of Toxicology.
[325] T. Webb,et al. Comparative pulmonary toxicity assessment of single-wall carbon nanotubes in rats. , 2003, Toxicological sciences : an official journal of the Society of Toxicology.
[326] C. Lamb,et al. Cancer in interstitial pulmonary fibrosis and sarcoidosis. , 2003, Current opinion in pulmonary medicine.
[327] J. Haseman,et al. Carcinogenicity of inhaled vanadium pentoxide in F344/N rats and B6C3F1 mice. , 2003, Toxicological sciences : an official journal of the Society of Toxicology.
[328] Y. C. Lee,et al. Benign asbestos pleural diseases. , 2003, Current opinion in pulmonary medicine.
[329] Maria Dusinska,et al. Measurement of DNA oxidation in human cells by chromatographic and enzymic methods. , 2003, Free radical biology & medicine.
[330] Norman C. Billingham,et al. Carbon nanotubes as polymer antioxidants , 2003 .
[331] J. Valentin. Basic anatomical and physiological data for use in radiological protection: reference values , 2002, Annals of the ICRP.
[332] J. Charlier,et al. Defects in carbon nanotubes. , 2002, Accounts of chemical research.
[333] W. Travis,et al. The new World Health Organization classification of lung tumours , 2001, European Respiratory Journal.
[334] V. Vallyathan,et al. A biomathematical model of particle clearance and retention in the lungs of coal miners. , 2001, Regulatory toxicology and pharmacology : RTP.
[335] K. Donaldson,et al. Impairment of alveolar macrophage phagocytosis by ultrafine particles. , 2001, Toxicology and applied pharmacology.
[336] P. Vacek,et al. Different accumulation of activated extracellular signal-regulated kinases (ERK 1/2) and role in cell-cycle alterations by epidermal growth factor, hydrogen peroxide, or asbestos in pulmonary epithelial cells. , 2001, American journal of respiratory cell and molecular biology.
[337] F. Hahn,et al. Influence of exposure concentration or dose on the distribution of particulate material in rat and human lungs. , 2001, Environmental health perspectives.
[338] Xianglin Shi,et al. Changes in bronchoalveolar lavage indices associated with radiographic classification in coal miners. , 2000, American journal of respiratory and critical care medicine.
[339] D. Wegman,et al. Implications of different fiber measures for epidemiologic studies of man-made vitreous fibers. , 2000, American journal of industrial medicine.
[340] H. Dosaka-akita,et al. Pneumoconiosis-related lung cancers: preferential occurrence from diffuse interstitial fibrosis-type pneumoconiosis. , 2000, American journal of respiratory and critical care medicine.
[341] Frankie Wood-Black,et al. NIOSH Pocket Guide to Chemical Hazards and Other Databases DHHS (NIOSH) Publication No. 99-115 , 2000 .
[342] H. Schulz,et al. Particle Deposition in the Respiratory Tract , 2000 .
[343] C. Arean,et al. Chemical aspects of the toxicity of inhaled mineral dusts , 2000 .
[344] D. Hanahan,et al. The Hallmarks of Cancer , 2000, Cell.
[345] S. Tsuda,et al. The Comet Assay with Multiple Mouse Organs: Comparison of Comet Assay Results and Carcinogenicity with 208 Chemicals Selected from the IARC Monographs and U.S. NTP Carcinogenicity Database** , 2000, Critical reviews in toxicology.
[346] D. B. McGregor,et al. The use of short-and medium-term tests for carcinogens and data on genetic effects in carcinogenic hazard evaluation. Consensus report. , 1999, IARC scientific publications.
[347] Diana Anderson,et al. Comet assay responses as indicators of carcinogen exposure. , 1998, Mutagenesis.
[348] S. Nishimura,et al. Asbestos-induced pleural disease. , 1998, Clinics in chest medicine.
[349] R. McClellan. Use of mechanistic data in assessing human risks from exposure to particles. , 1997, Environmental health perspectives.
[350] I. Adamson. Early mesothelial cell proliferation after asbestos exposure: in vivo and in vitro studies. , 1997, Environmental health perspectives.
[351] V. Cogliano,et al. Cancer risk assessment: historical perspectives, current issues, and future directions. , 1996, Drug and chemical toxicology.
[352] Y. Dragan,et al. Karyotypic changes in a multistage model of chemical hepatocarcinogenesis in the rat. , 1996, Cancer research.
[353] M. Jaurand,et al. Role of fibre characteristics on cytotoxicity and induction of anaphase/telophase aberrations in rat pleural mesothelial cells in vitro: correlations with in vivo animal findings. , 1995, Carcinogenesis.
[354] A. Zuckerman,et al. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans , 1995, IARC monographs on the evaluation of carcinogenic risks to humans.
[355] K S Crump,et al. The sizes, shapes, and mineralogy of asbestos structures that induce lung tumors or mesothelioma in AF/HAN rats following inhalation. , 1995, Risk analysis : an official publication of the Society for Risk Analysis.
[356] G. Oberdörster,et al. Lung particle overload: implications for occupational exposures to particles. , 1995, Regulatory toxicology and pharmacology : RTP.
[357] G. Oberdörster,et al. Macrophage-associated responses to chrysotile. , 1994, The Annals of occupational hygiene.
[358] J. Huff,et al. Cell proliferation and chemical carcinogenesis: a symposium overview. , 1993, Molecular carcinogenesis.
[359] I. Adamson,et al. Mesothelial cell proliferation after instillation of long or short asbestos fibers into mouse lung. , 1993, The American journal of pathology.
[360] M. Moriya. Single-stranded shuttle phagemid for mutagenesis studies in mammalian cells: 8-oxoguanine in DNA induces targeted G.C-->T.A transversions in simian kidney cells. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[361] Y. Dragan,et al. Stage of Tumor Progression, Progressor Agents, and Human Risk , 1993, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.
[362] H. Vainio. Mechanisms of Carcinogenesis in Risk Identification , 1992 .
[363] N. Lapp,et al. Acute silicosis responding to corticosteroid therapy. , 1992, Chest.
[364] P. Morrow,et al. Lung clearance and retention of toner, utilizing a tracer technique, during chronic inhalation exposure in rats. , 1991, Fundamental and applied toxicology : official journal of the Society of Toxicology.
[365] J. M. Davis,et al. Mesothelioma dose response following intraperitoneal injection of mineral fibres. , 1991, International journal of experimental pathology.
[366] A. Malkinson,et al. Genetic studies on lung tumor susceptibility and histogenesis in mice. , 1991, Environmental health perspectives.
[367] M Lippmann,et al. Effects of fiber characteristics on lung deposition, retention, and disease. , 1990, Environmental health perspectives.
[368] P. Morrow,et al. Possible mechanisms to explain dust overloading of the lungs. , 1988, Fundamental and applied toxicology : official journal of the Society of Toxicology.
[369] J Addison,et al. The pathogenicity of long versus short fibre samples of amosite asbestos administered to rats by inhalation and intraperitoneal injection. , 1986, British journal of experimental pathology.
[370] J. Vincent,et al. An overload hypothesis for pulmonary clearance of UICC amosite fibres inhaled by rats. , 1983, British journal of industrial medicine.
[371] M. Stanton,et al. Relation of particle dimension to carcinogenicity in amphibole asbestoses and other fibrous minerals. , 1981, Journal of the National Cancer Institute.
[372] A. B. Hill,et al. "The Environment and Disease: Association or Causation?" (1965), by Austin Bradford Hill , 2017 .
[373] D. Hyde,et al. Epithelial Cells of the Bronchiole , 2015 .
[374] Wei-Chung Su,et al. Estimation of carbon nanotubes deposition in a human respiratory tract replica , 2015 .
[375] Yi Cao,et al. Applications of the comet assay in particle toxicology: air pollution and engineered nanomaterials exposure. , 2015, Mutagenesis.
[376] A. Sutter,et al. Assessment of mechanisms driving non-linear dose-response relationships in genotoxicity testing. , 2015, Mutation research. Reviews in mutation research.
[377] OECD GUIDELINE FOR THE TESTING OF CHEMICALS In Vivo Mammalian Alkaline Comet Assay , 2014 .
[378] Fan Zhang,et al. The genotype-dependent influence of functionalized multiwalled carbon nanotubes on fetal development. , 2014, Biomaterials.
[379] E. Latz,et al. New insights into mechanisms controlling the NLRP3 inflammasome and its role in lung disease. , 2014, The American journal of pathology.
[380] Mohiuddin,et al. A novel genotoxicity assay of carbon nanotubes using functional macrophage receptor with collagenous structure (MARCO)-expressing chicken B lymphocytes , 2013, Archives of Toxicology.
[381] Kazuyuki Ishii,et al. [DNA damage in human pleural mesothelial cells induced by exposure to carbon nanotubes]. , 2012, Nihon eiseigaku zasshi. Japanese journal of hygiene.
[383] Fiona Murphy,et al. Identifying the pulmonary hazard of high aspect ratio nanoparticles to enable their safety-by-design. , 2011, Nanomedicine.
[384] S. Fukushima,et al. Pulmonary toxicity of intratracheally instilled multiwall carbon nanotubes in male Fischer 344 rats. , 2010, Industrial health.
[385] Jürgen Pauluhn,et al. Subchronic 13-week inhalation exposure of rats to multiwalled carbon nanotubes: toxic effects are determined by density of agglomerate structures, not fibrillar structures. , 2010, Toxicological sciences : an official journal of the Society of Toxicology.
[386] Marie Carrière,et al. Toxicological consequences of TiO2, SiC nanoparticles and multi-walled carbon nanotubes exposure in several mammalian cell types: an in vitro study , 2010 .
[387] A. Hart,et al. Exposure to nanoscale particles and fibers during machining of hybrid advanced composites containing carbon nanotubes , 2009 .
[388] François Béguin,et al. Structural defects play a major role in the acute lung toxicity of multiwall carbon nanotubes: toxicological aspects. , 2008, Chemical research in toxicology.
[389] Csaba Varga,et al. Lack of genotoxicity of carbon nanotubes in a pilot study. , 2008, Anticancer research.
[390] V. Castranova,et al. Alteration of deposition pattern and pulmonary response as a result of improved dispersion of aspirated single-walled carbon nanotubes in a mouse model. , 2008, American journal of physiology. Lung cellular and molecular physiology.
[391] U. Wahnschaffe. Transgenic animal mutagenicity assays , 2006 .
[392] Peter Møller,et al. Genotoxicity of environmental agents assessed by the alkaline comet assay. , 2005, Basic & clinical pharmacology & toxicology.
[393] I. Adamson,et al. KGF and HGF are growth factors for mesothelial cells in pleural lavage fluid after intratracheal asbestos. , 2001, Experimental Lung Research.
[394] F. J. Miller. Dosimetry of particles in laboratory animals and humans in relationship to issues surrounding lung overload and human health risk assessment: a critical review. , 2000, Inhalation toxicology.
[395] K. Donaldson,et al. Inhalation of poorly soluble particles. II. Influence Of particle surface area on inflammation and clearance. , 2000, Inhalation toxicology.
[396] Bernstein David,et al. Methods for the Determination of the Hazardous Properties for Human Health of Man Made Mineral Fibres (MMMF) , 1999 .
[397] T. Ebbesen,et al. TOPOLOGICAL AND SP3 DEFECT STRUCTURES IN NANOTUBES , 1995 .
[398] Icrp. Human Respiratory Tract Model for Radiological Protection , 1994 .
[399] Robert Gelein,et al. Increased Pulmonary Toxicity of Inhaled Ultrafine Particles: Due to Lung Overload Alone? , 1994 .
[400] N. Lapp,et al. How silicosis and coal workers' pneumoconiosis develop--a cellular assessment. , 1993, Occupational medicine.
[401] R. A. Parent,et al. Comparative biology of the normal lung , 1992 .
[402] R. Maronpot,et al. Proliferative lesions of the mouse lung: progression studies in strain A mice. , 1991, Experimental lung research.
[403] W. Rom. Relationship of inflammatory cell cytokines to disease severity in individuals with occupational inorganic dust exposure. , 1991, American journal of industrial medicine.
[404] M. Roller,et al. Tumours by the Intraperitoneal and Intrapleural Routes and their Significance for the Classification of Mineral Fibres , 1991 .
[405] O. Creutzenberg,et al. Dust overloading of lungs after exposure of rats to particles of low solubility: Comparative studies , 1990 .
[406] M B Snipes,et al. Long-term retention and clearance of particles inhaled by mammalian species. , 1989, Critical reviews in toxicology.
[407] F. Huth,et al. Carcinogenicity studies on fibres, metal compounds, and some other dusts in rats. , 1987, Experimental pathology.
[408] J. Higginson,et al. International Agency for Research on Cancer. , 1968, WHO chronicle.