The prognostic value of computerized tomography in comatose head-injured patients.

In a series of 121 comatose head-injured patients, computerized tomography (CT) scans were obtained at various intervals after onset of coma. The scans were classified without knowledge of previous scans or of the patient's clinical state, and predictions as to outcome at 1 year were made based on clinical features and CT findings. The state of the basal cisterns as seen on CT scans proved to be a very powerful prognosticator. Subsets of features with the greatest prognostic weight were selected systematically for CT features, clinical features, and for a combination of CT and clinical features. With these features, probability statements were made about death or survival at 1 year. The quality of the predictions was established by comparing them with actual outcome. The percentage of accurate predictions was markedly higher with a combination of clinical and CT features than with clinical or CT features alone.

[1]  H. Schouten,et al.  Megadose steroids in severe head injury. Results of a prospective double-blind clinical trial. , 1983, Journal of neurosurgery.

[2]  J. Fernandes,et al.  LACTATE AS ENERGY SOURCE FOR BRAIN IN GLUCOSE-6-PHOSPHATASE DEFICIENT CHILD , 1982, The Lancet.

[3]  G. Teasdale,et al.  Evoked potentials in severe head injury--analysis and relation to outcome. , 1981, Journal of neurology, neurosurgery, and psychiatry.

[4]  J D Habbema,et al.  A computer program for selection of variables in diagnostic and prognostic problems. , 1981, Computer programs in biomedicine.

[5]  R. Narayan,et al.  Prognostic implications of early multimodality evoked potentials in severely head-injured patients. A prospective study. , 1981, Journal of neurosurgery.

[6]  J. Miller,et al.  Traumatic acute subdural hematoma: major mortality reduction in comatose patients treated within four hours. , 1981, The New England journal of medicine.

[7]  G G Enas,et al.  Improved confidence of outcome prediction in severe head injury. A comparative analysis of the clinical examination, multimodality evoked potentials, CT scanning, and intracranial pressure. , 1981, Journal of neurosurgery.

[8]  D. Titterington,et al.  Comparison of Discrimination Techniques Applied to a Complex Data Set of Head Injured Patients , 1981 .

[9]  J. Selhorst,et al.  Further experience in the management of severe head injury. , 1981, Journal of neurosurgery.

[10]  R. Grossman,et al.  Neurological course and correlated computerized tomography findings after severe closed head injury. , 1980, Journal of neurosurgery.

[11]  J. Habbema,et al.  Systematic selection of prognostic features in patients with severe head injury. , 1980, Neurosurgery.

[12]  D. Seales,et al.  Brainstem auditory evoked responses in patients comatose as a result of blunt head trauma. , 1979, The Journal of trauma.

[13]  B Jennett,et al.  Prognosis of patients with severe head injury. , 1979, Neurosurgery.

[14]  L. Sutton,et al.  Outcome following severe head injuries in children. , 1978, Journal of neurosurgery.

[15]  D. Thomas,et al.  SERUM-MYELIN-BASIC-PROTEIN ASSAY IN DIAGNOSIS AND PROGNOSIS OF PATIENTS WITH HEAD INJURY , 1978, The Lancet.

[16]  M. Rosner,et al.  Significance of intracranial hypertension in severe head injury. , 1977, Journal of neurosurgery.

[17]  J. Miller,et al.  The outcome from severe head injury with early diagnosis and intensive management. , 1977, Journal of neurosurgery.

[18]  J. Miller,et al.  Evaluation of brain function in severe human head trauma with multimodality evoked potentials. Part 2: Localization of brain dysfunction and correlation with posttraumatic neurological conditions. , 1977, Journal of neurosurgery.

[19]  J. Miller,et al.  Evaluation of brain function in severe human head trauma with multimodality evoked potentials. Part 1: Evoked brain-injury potentials, methods, and analysis. , 1977, Journal of neurosurgery.

[20]  B Jennett,et al.  PREDICTING OUTCOME IN INDIVIDUAL PATIENTS AFTER SEVERE HEAD INJURY , 1976, The Lancet.

[21]  B. Jennett,et al.  ASSESSMENT OF OUTCOME AFTER SEVERE BRAIN DAMAGE A Practical Scale , 1975, The Lancet.

[22]  G. Gaist,et al.  Clinical course and prognosis of acute post-traumatic coma. , 1975, Journal of neurology, neurosurgery, and psychiatry.

[23]  B. Jennett,et al.  Assessment of coma and impaired consciousness. A practical scale. , 1974, Lancet.

[24]  W. Tweed,et al.  Prognosis after head injury based on early clinical examination. , 1973, Lancet.

[25]  P. Sipponen,et al.  PROGNOSIS OF SEVERE BRAIN INJURY , 1970, Acta neurologica Scandinavica.

[26]  C. Carlsson,et al.  Factors Affecting the Clinical Course of Patients with Severe Head Injuries , 1968 .

[27]  B Jennett,et al.  Adding up the Glasgow Coma Score. , 1979, Acta neurochirurgica. Supplementum.

[28]  R. Knill-Jones,et al.  The prediction of outcome of patients admitted following head injury in coma with bilateral fixed pupils. , 1979, Acta neurochirurgica. Supplementum.

[29]  R. Frowein Prognostic assessment of coma in relation to age. , 1979, Acta neurochirurgica. Supplementum.

[30]  C. Avezaat,et al.  Eye movements as a prognostic factor. , 1979, Acta neurochirurgica. Supplementum.

[31]  F. Cordobés,et al.  Prognostic value of the intracranial pressure levels during the acute phase of severe head injuries. , 1979, Acta neurochirurgica. Supplementum.

[32]  W. Lewin,et al.  Long-term prognosis after severe head injury. , 1979, Acta neurochirurgica. Supplementum.

[33]  M. Gaab,et al.  The prognostic value of osmolality within the first week of sustaining head injury. , 1979, Acta neurochirurgica. Supplementum.

[34]  F. Miltner,et al.  Prognostic aspects of electroclinical and neuroendocrine data in severe brain injury. , 1979, Acta neurochirurgica. Supplementum.

[35]  L. Marshall,et al.  The outcome with aggressive treatment in severe head injuries. Part I: the significance of intracranial pressure monitoring. , 1979, Journal of neurosurgery.

[36]  J. Garlock Carcinoma of the oesophagus and upper stomach. , 1947, Lancet.