Combination of GNRs-PEI/cGAMP-laden macrophages-based photothermal induced in situ tumor vaccines and immune checkpoint blockade for synergistic anti-tumor immunotherapy.

[1]  Jyh-Ping Chen,et al.  Magnetic and GRPR-targeted reduced graphene oxide/doxorubicin nanocomposite for dual-targeted chemo-photothermal cancer therapy. , 2021, Materials science & engineering. C, Materials for biological applications.

[2]  X. Wen,et al.  Integrating disulfides into a polyethylenimine gene carrier selectively boosts significant transfection activity in lung tissue enabling robust IL-12 gene therapy against metastatic lung cancers. , 2021, Materials science & engineering. C, Materials for biological applications.

[3]  Ronghui Zhou,et al.  Aptamer-guided DNA tetrahedrons as a photo-responsive drug delivery system for Mucin 1-expressing breast cancer cells , 2021, Applied Materials Today.

[4]  Y. Liu,et al.  Nanotechnology: Breaking the Current Treatment Limits of Lung Cancer , 2021, Advanced healthcare materials.

[5]  C. Miralles,et al.  Recent advances in early stage lung cancer , 2021, Journal of clinical and translational research.

[6]  Shi-yong Zhou,et al.  Cancer Cell Membrane Camouflaged Mesoporous Silica Nanoparticles Combined with Immune Checkpoint Blockade for Regulating Tumor Microenvironment and Enhancing Antitumor Therapy , 2021, International journal of nanomedicine.

[7]  Xiao Zhu,et al.  The metastasizing mechanisms of lung cancer: Recent advances and therapeutic challenges. , 2021, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[8]  Ho-Yyoung Lee,et al.  Mechanisms of resistance to chemotherapy in non-small cell lung cancer , 2021, Archives of Pharmacal Research.

[9]  Shujun Fu,et al.  CD133 peptide-conjugated pyropheophorbide-a as a novel photosensitizer for targeted photodynamic therapy in colorectal cancer stem cells. , 2021, Biomaterials science.

[10]  Jianying Zhou,et al.  The progress and challenge of anti-PD-1/PD-L1 immunotherapy in treating non-small cell lung cancer , 2021, Therapeutic advances in medical oncology.

[11]  Nicholas R. Anderson,et al.  Macrophage-Based Approaches for Cancer Immunotherapy , 2020, Cancer Research.

[12]  Xunxia Bao,et al.  Mechanisms and Future of Non-Small Cell Lung Cancer Metastasis , 2020, Frontiers in Oncology.

[13]  Xuesi Chen,et al.  An immune cocktail therapy to realize multiple boosting of the cancer-immunity cycle by combination of drug/gene delivery nanoparticles , 2020, Science Advances.

[14]  Toshitaka Nakamura,et al.  Circulating tumor cells detected only after surgery for non-small cell lung cancer: is it a predictor of recurrence? , 2020, Journal of thoracic disease.

[15]  Wei Wang,et al.  Mesenchymal Stem Cells Mediated Drug Delivery in Tumor-Targeted Therapy. , 2020, Current drug delivery.

[16]  J. Zou,et al.  Burst release of encapsulated annexin A5 in tumours boosts cytotoxic T-cell responses by blocking the phagocytosis of apoptotic cells , 2020, Nature Biomedical Engineering.

[17]  Xuesi Chen,et al.  Synergistic tumor immunological strategy by combining tumor nanovaccine with gene-mediated extracellular matrix scavenger. , 2020, Biomaterials.

[18]  R. Ruiz-Cordero,et al.  Targeted Therapy and Checkpoint Immunotherapy in Lung Cancer. , 2020, Surgical pathology clinics.

[19]  P. Allavena,et al.  PLGA Based Nanoparticles for the Monocyte-Mediated Anti-Tumor Drug Delivery System. , 2020, Journal of biomedical nanotechnology.

[20]  A. Garanina,et al.  Neutrophil-mediated transport is crucial for short-circulating magnetic nanoparticles delivery to tumors. , 2020, Acta biomaterialia.

[21]  Zhihong Yang,et al.  Cell-mediated targeting drugs delivery systems , 2020, Drug delivery.

[22]  Xuesi Chen,et al.  Tumor microenvironment as the “regulator” and “target” for gene therapy , 2019, The journal of gene medicine.

[23]  J. Ting,et al.  A microparticle platform for STING-targeted immunotherapy enhances natural killer cell- and CD8+ T cell-mediated anti-tumor immunity. , 2019, Biomaterials.

[24]  N. Kawazoe,et al.  Encapsulation of individual living cells with enzyme responsive polymer nanoshell. , 2019, Biomaterials.

[25]  Lin Mei,et al.  Surgical Tumor-Derived Personalized Photothermal Vaccine Formulation for Cancer Immunotherapy. , 2019, ACS nano.

[26]  S. Koch,et al.  Phase Ib evaluation of a self-adjuvanted protamine formulated mRNA-based active cancer immunotherapy, BI1361849 (CV9202), combined with local radiation treatment in patients with stage IV non-small cell lung cancer , 2019, Journal of Immunotherapy for Cancer.

[27]  Xuesi Chen,et al.  Efficient PD‐L1 gene silence promoted by hyaluronidase for cancer immunotherapy , 2019, Journal of controlled release : official journal of the Controlled Release Society.

[28]  Leaf Huang,et al.  Nanoparticle-Mediated Remodeling of the Tumor Microenvironment to Enhance Immunotherapy. , 2018, ACS nano.

[29]  Kanyi Pu,et al.  Recent Advances in Cell Membrane-Camouflaged Nanoparticles for Cancer Phototherapy. , 2018, Small.

[30]  Xuesi Chen,et al.  Polycations for Gene Delivery: Dilemmas and Solutions. , 2018, Bioconjugate chemistry.

[31]  Xuesi Chen,et al.  Gold Nanorods Electrostatically Binding Nucleic Acid Probe for In Vivo MicroRNA Amplified Detection and Photoacoustic Imaging‐Guided Photothermal Therapy , 2018 .

[32]  Jing-lan Kan,et al.  Surface Decorated Porphyrinic Nanoscale Metal-Organic Framework for Photodynamic Therapy. , 2018, Inorganic chemistry.

[33]  Xuesi Chen,et al.  Macrophages loaded CpG and GNR-PEI for combination of tumor photothermal therapy and immunotherapy , 2018, Science China Materials.

[34]  J. Taube,et al.  PD-L1 on host cells is essential for PD-L1 blockade–mediated tumor regression , 2018, The Journal of clinical investigation.

[35]  Xuesi Chen,et al.  Gold-Nanorods-Based Gene Carriers with the Capability of Photoacoustic Imaging and Photothermal Therapy. , 2016, ACS applied materials & interfaces.

[36]  T. Choueiri,et al.  Tumor control with PD-1 inhibition in a patient with concurrent metastatic melanoma and renal cell carcinoma , 2016, Journal of Immunotherapy for Cancer.

[37]  Liangzhu Feng,et al.  Hyaluronidase To Enhance Nanoparticle-Based Photodynamic Tumor Therapy. , 2016, Nano letters.

[38]  A. Ribas,et al.  Combination cancer immunotherapies tailored to the tumour microenvironment , 2016, Nature Reviews Clinical Oncology.

[39]  H. Rammensee,et al.  Long-term survival correlates with immunological responses in renal cell carcinoma patients treated with mRNA-based immunotherapy , 2015, Oncoimmunology.

[40]  D. Irvine,et al.  Synthetic Nanoparticles for Vaccines and Immunotherapy. , 2015, Chemical reviews.

[41]  P. Chu,et al.  Ultrasmall Black Phosphorus Quantum Dots: Synthesis and Use as Photothermal Agents. , 2015, Angewandte Chemie.

[42]  G. Beatty,et al.  Immune Escape Mechanisms as a Guide for Cancer Immunotherapy , 2014, Clinical Cancer Research.

[43]  R. Emerson,et al.  PD-1 blockade induces responses by inhibiting adaptive immune resistance , 2014, Nature.

[44]  P. Kubes,et al.  Macrophages eliminate circulating tumor cells after monoclonal antibody therapy. , 2014, The Journal of clinical investigation.

[45]  M. McNutt Cancer Immunotherapy , 2013, Science.

[46]  R. Jain,et al.  Normalization of tumour blood vessels improves the delivery of nanomedicines in a size-dependent manner , 2012, Nature nanotechnology.

[47]  C. Higano,et al.  PROVENGE (Sipuleucel-T) in Prostate Cancer: The First FDA-Approved Therapeutic Cancer Vaccine , 2011, Clinical Cancer Research.

[48]  L. Mileshkin,et al.  In vivo tracking of macrophage activated killer cells to sites of metastatic ovarian carcinoma , 2006, Cancer Immunology, Immunotherapy.

[49]  Antoni Ribas,et al.  Current developments in cancer vaccines and cellular immunotherapy. , 2003, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[50]  C. Scheibenbogen,et al.  Adoptive transfer of tumor cytotoxic macrophages generated in vitro from circulating blood monocytes: a new approach to cancer immunotherapy. , 1990, Cancer research.

[51]  A. Sahebkar,et al.  A Review of Monoclonal Antibody-Based Treatments in Non-small Cell Lung Cancer. , 2021, Advances in experimental medicine and biology.

[52]  V. Kaever,et al.  cGAMP Quantification in Virus-Infected Human Monocyte-Derived Cells by HPLC-Coupled Tandem Mass Spectrometry. , 2017, Methods in molecular biology.

[53]  P. Fisher,et al.  Therapeutic cancer vaccines: past, present, and future. , 2013, Advances in cancer research.