An Exit Strategy for Measles Virus

A receptor for measles virus on epithelial cells reveals how the virus accesses the respiratory tract. The causative agent of measles is one of the most infectious viruses known—each infected person can transmit the virus to 15 to 20 susceptible individuals. Identification of the cell adhesion molecule nectin-4 as an epithelial cell receptor for measles virus (1, 2) provides insight into how this high rate of transmission is achieved.

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