Binocular function in patients with age-related macular degeneration: a review.

Normally sighted observers typically benefit from binocular viewing when monocular sensitivities are equivalent. Age-related macular degeneration (AMD) not only destroys the foveal vision, however, but it also affects the 2 eyes unequally, providing grounds for impairment of binocular function. The aim of the present article is to provide a review of the current research on the effect of AMD on binocular vision. The main findings to date reveal that a high proportion of patients show characteristics of binocular contrast inhibition at low and medium spatial frequencies. Yet binocular acuity gain is not different from that of age-matched control participants without AMD. Additional findings show that rivalry processes are severely disrupted in patients with AMD. The effects of the disease on other binocular functions have yet to be explored. Knowledge of binocular function in AMD may one day help clinicians decide on the most appropriate management and rehabilitation techniques.

[1]  M. Steinbach,et al.  Binocular interactions in patients with age-related macular degeneration: Acuity summation and rivalry , 2006, Vision Research.

[2]  R. Klein,et al.  Causes and prevalence of visual impairment among adults in the United States. , 2004, Archives of ophthalmology.

[3]  K. Ukai,et al.  Binocular Rivalry Alternation Rate Declines with Age , 2003, Perceptual and motor skills.

[4]  A. Rudnicka,et al.  How big is the burden of visual loss caused by age related macular degeneration in the United Kingdom? , 2003, The British journal of ophthalmology.

[5]  D. Kline,et al.  Senescent effects on binocular summation for contrast sensitivity and spatial interval acuity , 2003, Current eye research.

[6]  S. Pardhan,et al.  Binocular summation to gratings in the peripheral field in older subjects is spatial frequency dependent , 2003, Current eye research.

[7]  JAN E. LOVIE-KITCHIN,et al.  Vision and Mobility Performance of Subjects with Age-Related Macular Degeneration , 2002, Optometry and vision science : official publication of the American Academy of Optometry.

[8]  P. Artes,et al.  Face recognition in age related macular degeneration: perceived disability, measured disability, and performance with a bioptic device , 2002, The British journal of ophthalmology.

[9]  Rohit Varma,et al.  Binocular visual acuity summation and inhibition in an ocular epidemiological study: the Los Angeles Latino Eye Study. , 2002, Investigative ophthalmology & visual science.

[10]  D. Quillen.  Effect of unilateral exudative age-related macular degeneration on binocular visual function. , 2001, Archives of ophthalmology.

[11]  J. Faubert,et al.  Binocular Vision in Older People with Adventitious Visual Impairment: Sometimes One Eye Is Better than Two , 2000, Journal of the American Geriatrics Society.

[12]  S Pardhan,et al.  Binocular summation in the fovea and peripheral field of anisometropic amblyopes , 2000, Current eye research.

[13]  David A. Leopold,et al.  What is rivalling during binocular rivalry? , 1996, Nature.

[14]  S. Pardhan.  A comparison of binocular summation in young and older patients. , 1996, Current eye research.

[15]  Shirley Rietdyk,et al.  The Waterloo Vision and Mobility Study: postural control strategies in subjects with ARM , 1995 .

[16]  A Arditi,et al.  Binocular enhancement of visual acuity. , 1993, Journal of the Optical Society of America. A, Optics, image science, and vision.

[17]  R. Blake,et al.  Spatial zones of binocular rivalry in central and peripheral vision , 1992, Visual Neuroscience.

[18]  R. Sireteanu,et al.  The time course of interocular suppression in normal and amblyopic subjects. , 1991, Investigative ophthalmology & visual science.

[19]  I L Bailey,et al.  Face recognition in age-related maculopathy. , 1991, Investigative ophthalmology & visual science.

[20]  J. Gilchrist,et al.  Binocular Inhibition: Psychophysical and Electrophysiological Evidence , 1990, Optometry and vision science : official publication of the American Academy of Optometry.

[21]  T. Jenkins,et al.  Binocular summation in visually evoked responses and visual acuity , 1990, Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians.

[22]  D L Guyton,et al.  Eccentric visual acuity in patients with macular disease. , 1985, Ophthalmology.

[23]  A. Bron,et al.  Effect of age on contrast sensitivity function: uniocular and binocular findings. , 1985, The British journal of ophthalmology.

[24]  R. Home,et al.  Binocular summation: A study of contrast sensitivity, visual acuity and recognition , 1978, Vision Research.

[25]  Robert Fox,et al.  The psychophysical inquiry into binocular summation , 1973 .

[26]  W. Levelt.  The alternation process in binocular rivalry , 1966 .

[27]  M W HOROWITZ,et al.  An analysis of the superiority of binocular over monocular visual acuity. , 1949, Journal of experimental psychology.

[28]  Health and Quality of Life Outcomes , 2005 .

[29]  Johanna M. Seddon,et al.  The Epidemiology of Age-Related Macular Degeneration , 2004, International ophthalmology clinics.

[30]  Michael Stur,et al.  Scotoma size and reading speed in patients with subfoveal occult choroidal neovascularization in age-related macular degeneration. , 2003, Ophthalmology.

[31]  A. Valberg,et al.  Binocular contrast inhibition in subjects with age-related macular degeneration. , 2002, Journal of the Optical Society of America. A, Optics, image science, and vision.

[32]  S. Pardhan.  A comparison of binocular summation in the peripheral visual field in young and older patients. , 1997, Current eye research.

[33]  R. H. Taylor,et al.  Visual acuity and contrast sensitivity in cataract: Summation and inhibition of visual performance , 1991, Eye.