Host immune responses to rhinovirus: mechanisms in asthma.

[1]  W. Busse,et al.  The presence of rhinovirus in lower airways of patients with bronchial asthma. , 2008, American journal of respiratory and critical care medicine.

[2]  Rosella Ombrato,et al.  New anti-viral drugs for the treatment of the common cold. , 2008, Bioorganic & medicinal chemistry.

[3]  Jian-Dong Huang,et al.  Salvianolic Acid B Inhibits Hydrogen Peroxide-Induced Endothelial Cell Apoptosis through Regulating PI3K/Akt Signaling , 2007, PloS one.

[4]  I. Ghiran,et al.  Airway Eosinophils: Allergic Inflammation Recruited Professional Antigen-Presenting Cells1 , 2007, The Journal of Immunology.

[5]  Wai-ming Lee,et al.  A Diverse Group of Previously Unrecognized Human Rhinoviruses Are Common Causes of Respiratory Illnesses in Infants , 2007, PloS one.

[6]  P. Woo,et al.  Clinical Features and Complete Genome Characterization of a Distinct Human Rhinovirus (HRV) Genetic Cluster, Probably Representing a Previously Undetected HRV Species, HRV-C, Associated with Acute Respiratory Illness in Children , 2007, Journal of Clinical Microbiology.

[7]  S. Phipps,et al.  Eosinophils contribute to innate antiviral immunity and promote clearance of respiratory syncytial virus. , 2007, Blood.

[8]  S. Johnston,et al.  IFN-γ–induced protein 10 is a novel biomarker of rhinovirus-induced asthma exacerbations , 2007, Journal of Allergy and Clinical Immunology.

[9]  E. Zdobnov,et al.  New complete genome sequences of human rhinoviruses shed light on their phylogeny and genomic features , 2007, BMC Genomics.

[10]  I. Sayers,et al.  Human bronchial epithelial cells express an active and inducible biosynthetic pathway for leukotrienes B4 and C4 , 2007, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

[11]  S. Johnston,et al.  Corticosteroids and β2 Agonists Differentially Regulate Rhinovirus-induced Interleukin-6 via Distinct Cis-acting Elements* , 2007, Journal of Biological Chemistry.

[12]  M. Chan-yeung,et al.  Relationship of early childhood viral exposures to respiratory symptoms, onset of possible asthma and atopy in high risk children: The Canadian asthma primary prevention study , 2007, Pediatric pulmonology.

[13]  Amanda J Lee,et al.  Short-course montelukast for intermittent asthma in children: a randomized controlled trial. , 2007, American journal of respiratory and critical care medicine.

[14]  O. Ruuskanen,et al.  Prednisolone reduces recurrent wheezing after a first wheezing episode associated with rhinovirus infection or eczema , 2006, Journal of Allergy and Clinical Immunology.

[15]  W. Teague,et al.  Prevalence of viral respiratory tract infections in children with asthma , 2006, Journal of Allergy and Clinical Immunology.

[16]  T. Haahtela,et al.  Human rhinovirus in bronchial epithelium of infants with recurrent respiratory symptoms. , 2006, The Journal of allergy and clinical immunology.

[17]  S. Johnston,et al.  Rhinovirus Replication in Human Macrophages Induces NF-κB-Dependent Tumor Necrosis Factor Alpha Production , 2006, Journal of Virology.

[18]  Stephen T Holgate,et al.  Role of deficient type III interferon-λ production in asthma exacerbations , 2006, Nature Medicine.

[19]  W. Busse,et al.  The Relationship of Rhinovirus-Associated Asthma Hospitalizations with Inhaled Corticosteroids and Smoking , 2006, The Journal of infectious diseases.

[20]  James J. Lee,et al.  Eosinophils Can Function as Antigen-Presenting Cells To Induce Primary and Secondary Immune Responses to Strongyloides stercoralis , 2006, Infection and Immunity.

[21]  H. Boushey,et al.  Rhinovirus induces airway epithelial gene expression through double-stranded RNA and IFN-dependent pathways. , 2006, American journal of respiratory cell and molecular biology.

[22]  S. Johnston,et al.  Role of deficient type III interferon-lambda production in asthma exacerbations. , 2006, Nature medicine.

[23]  A. Woodcock,et al.  Study of modifiable risk factors for asthma exacerbations: virus infection and allergen exposure increase the risk of asthma hospital admissions in children , 2005, Thorax.

[24]  F. Hayden,et al.  Relationship of Pleconaril Susceptibility and Clinical Outcomes in Treatment of Common Colds Caused by Rhinoviruses , 2005, Antimicrobial Agents and Chemotherapy.

[25]  S. Johnston,et al.  IL-1β induces IL-8 in bronchial cells via NF-κB and NF-IL6 transcription factors and can be suppressed by glucocorticoids , 2005 .

[26]  R. Gangnon,et al.  Rhinovirus illnesses during infancy predict subsequent childhood wheezing. , 2005, The Journal of allergy and clinical immunology.

[27]  P. Gibson,et al.  Interleukin-10 gene expression in acute virus-induced asthma. , 2005, American journal of respiratory and critical care medicine.

[28]  D. Proud,et al.  Human airway epithelial cells produce IP-10 (CXCL10) in vitro and in vivo upon rhinovirus infection. , 2005, American journal of physiology. Lung cellular and molecular physiology.

[29]  H. Donninger,et al.  Persistence of rhinovirus RNA after asthma exacerbation in children , 2005, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

[30]  I. Pandrea,et al.  Immune responses induced by intranasal imiquimod and implications for therapeutics in rhinovirus infections , 2005, Journal of cellular and molecular medicine.

[31]  S. Johnston,et al.  Asthmatic bronchial epithelial cells have a deficient innate immune response to infection with rhinovirus , 2005, The Journal of experimental medicine.

[32]  H. Bisgaard,et al.  Montelukast reduces asthma exacerbations in 2- to 5-year-old children with intermittent asthma. , 2005, American journal of respiratory and critical care medicine.

[33]  S. Johnston,et al.  IL-1beta induces IL-8 in bronchial cells via NF-kappaB and NF-IL6 transcription factors and can be suppressed by glucocorticoids. , 2005, Pulmonary pharmacology & therapeutics.

[34]  A. Ghahary,et al.  Cutting Edge: Human Eosinophils Regulate T Cell Subset Selection through Indoleamine 2,3-Dioxygenase1 , 2004, The Journal of Immunology.

[35]  F. Hayden,et al.  Viral infections in relation to age, atopy, and season of admission among children hospitalized for wheezing☆ , 2004, Journal of Allergy and Clinical Immunology.

[36]  Daniel C. Pevear,et al.  VP1 Sequencing of All Human Rhinovirus Serotypes:Insights into Genus Phylogeny and Susceptibility to AntiviralCapsid-BindingCompounds , 2004, Journal of Virology.

[37]  R. Fleischer,et al.  Safety and efficacy evaluation of pleconaril for treatment of the common cold. , 2003, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[38]  M. Gersten,et al.  Phase II, Randomized, Double-Blind, Placebo-Controlled Studies of Ruprintrivir Nasal Spray 2-Percent Suspension for Prevention and Treatment of Experimentally Induced Rhinovirus Colds in Healthy Volunteers , 2003, Antimicrobial Agents and Chemotherapy.

[39]  K. Rabe,et al.  Are rhinovirus-induced airway responses in asthma aggravated by chronic allergen exposure? , 2003, American journal of respiratory and critical care medicine.

[40]  D. Gentile,et al.  Elevations of local leukotriene C4 levels during viral upper respiratory tract infections. , 2003, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

[41]  Spencer Hudson,et al.  Efficacy and Safety of Oral Pleconaril for Treatment of Colds Due to Picornaviruses in Adults: Results of 2 Double-Blind, Randomized, Placebo-Controlled Trials , 2003, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[42]  A. Fendrick Viral Respiratory Infections Due to Rhinoviruses: Current Knowledge, New Developments , 2003, American journal of therapeutics.

[43]  F. Hayden,et al.  Experimental rhinovirus challenges in adults with mild asthma: response to infection in relation to IgE. , 2003, The Journal of allergy and clinical immunology.

[44]  Ianessa Morantte,et al.  Prevention of Human Rhinovirus Infection by Multivalent Fab Molecules Directed against ICAM-1 , 2003, Antimicrobial Agents and Chemotherapy.

[45]  G. Cuda,et al.  Molecular mechanisms of corticosteroid actions in chronic inflammatory airway diseases. , 2003, Life sciences.

[46]  S. Greenberg Respiratory consequences of rhinovirus infection. , 2003, Archives of internal medicine.

[47]  Kunling Shen,et al.  Relationships among specific viral pathogens, virus‐induced interleukin‐8, and respiratory symptoms in infancy , 2002, Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology.

[48]  M. Stanley,et al.  Imiquimod and the imidazoquinolones: mechanism of action and therapeutic potential , 2002, Clinical and experimental dermatology.

[49]  N. Papadopoulos,et al.  A defective type 1 response to rhinovirus in atopic asthma , 2002, Thorax.

[50]  Stephen T Holgate,et al.  Frequency, severity, and duration of rhinovirus infections in asthmatic and non-asthmatic individuals: a longitudinal cohort study , 2002, The Lancet.

[51]  W. Busse,et al.  Relationship of viral infections to wheezing illnesses and asthma , 2002, Nature Reviews Immunology.

[52]  P. Gibson,et al.  Neutrophil degranulation and cell lysis is associated with clinical severity in virus-induced asthma , 2002, European Respiratory Journal.

[53]  G. Cuda,et al.  Effects of glucocorticoids on activation of c-jun N-terminal, extracellular signal-regulated, and p38 MAP kinases in human pulmonary endothelial cells. , 2001, Biochemical pharmacology.

[54]  S. Johnston,et al.  The immunology of virus infection in asthma , 2001, European Respiratory Journal.

[55]  E. D. de KLERK,et al.  Rhinovirus-induced airway inflammation in asthma: effect of treatment with inhaled corticosteroids before and during experimental infection. , 2001, American journal of respiratory and critical care medicine.

[56]  H. Rosenberg,et al.  Eosinophils, eosinophil ribonucleases, and their role in host defense against respiratory virus pathogens , 2001, Journal of leukocyte biology.

[57]  W. Fokkens,et al.  Prolonged nasal eosinophilia in all_ergic patients after common cold , 2001, Allergy.

[58]  S. Holgate,et al.  Rhinovirus infection up‐regulates eotaxin and eotaxin‐2 expression in bronchial epithelial cells , 2001, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

[59]  W. Busse,et al.  Relationship of upper and lower airway cytokines to outcome of experimental rhinovirus infection. , 2000, American journal of respiratory and critical care medicine.

[60]  L. Pacifico,et al.  Chemokine concentrations in nasal washings of infants with rhinovirus illnesses. , 2000, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[61]  R. Knight,et al.  Expression of intercellular adhesion molecule‐1 (ICAM‐1) in nasal epithelial cells of atopic subjects: a mechanism for increased rhinovirus infection? , 2000, Clinical and experimental immunology.

[62]  H. Rotbart Antiviral Therapy for Enteroviruses and Rhinoviruses , 2000, Antiviral chemistry & chemotherapy.

[63]  W. Busse,et al.  The effect of an experimental rhinovirus 16 infection on bronchial lavage neutrophils. , 2000, The Journal of allergy and clinical immunology.

[64]  J. Abisheganaden,et al.  Effects of allergic inflammation of the nasal mucosa on the severity of rhinovirus 16 cold. , 2000, The Journal of allergy and clinical immunology.

[65]  P. Dragovich,et al.  Inhibition of Human Rhinovirus-Induced Cytokine Production by AG7088, a Human Rhinovirus 3C Protease Inhibitor , 2000, Antimicrobial Agents and Chemotherapy.

[66]  W. Busse,et al.  Rhinovirus-induced PBMC responses and outcome of experimental infection in allergic subjects. , 2000, The Journal of allergy and clinical immunology.

[67]  P. Barnes,et al.  Changes in sputum eosinophils predict loss of asthma control. , 2000, American journal of respiratory and critical care medicine.

[68]  M. Schroth,et al.  Rhinovirus replication causes RANTES production in primary bronchial epithelial cells. , 1999, American journal of respiratory cell and molecular biology.

[69]  F. Hayden,et al.  Efficacy of tremacamra, a soluble intercellular adhesion molecule 1, for experimental rhinovirus infection: a randomized clinical trial. , 1999, JAMA.

[70]  N. Papadopoulos,et al.  Rhinoviruses replicate effectively at lower airway temperatures , 1999, Journal of medical virology.

[71]  S. Johnston,et al.  Rhinovirus Infection Induces Expression of Its Own Receptor Intercellular Adhesion Molecule 1 (ICAM-1) via Increased NF-κB-mediated Transcription* , 1999, The Journal of Biological Chemistry.

[72]  R. Rabin,et al.  Chemokine receptor responses on T cells are achieved through regulation of both receptor expression and signaling. , 1999, Journal of immunology.

[73]  M. Pallansch,et al.  Molecular Evolution of the Human Enteroviruses: Correlation of Serotype with VP1 Sequence and Application to Picornavirus Classification , 1999, Journal of Virology.

[74]  R. Knight,et al.  Th2 cytokines exert a dominant influence on epithelial cell expression of the major group human rhinovirus receptor, ICAM-1. , 1998, The European respiratory journal.

[75]  R. Sorkness,et al.  Attenuation of virus-induced airway dysfunction in rats treated with imiquimod. , 1998, The European respiratory journal.

[76]  W. Busse,et al.  Eosinophils bind rhinovirus and activate virus-specific T cells. , 1998, Journal of immunology.

[77]  D. Postma,et al.  Effect of inhaled formoterol and budesonide on exacerbations of asthma. Formoterol and Corticosteroids Establishing Therapy (FACET) International Study Group. , 1997, The New England journal of medicine.

[78]  J. Elias,et al.  Rhinovirus stimulation of interleukin-8 in vivo and in vitro: role of NF-kappaB. , 1997, The American journal of physiology.

[79]  K. Nakayama,et al.  Rhinovirus infection of primary cultures of human tracheal epithelium: role of ICAM-1 and IL-1beta. , 1997, The American journal of physiology.

[80]  Weiliang Tang,et al.  Rhinovirus stimulation of interleukin-8 in vivo and in vitro: role of NF-κB. , 1997, American journal of physiology. Lung cellular and molecular physiology.

[81]  M. Yamaya,et al.  Rhinovirus infection of primary cultures of human tracheal epithelium: role of ICAM-1 and IL-1β. , 1997, American journal of physiology. Lung cellular and molecular physiology.

[82]  E. D. de KLERK,et al.  Experimental rhinovirus 16 infection. Effects on cell differentials and soluble markers in sputum in asthmatic subjects. , 1997, American journal of respiratory and critical care medicine.

[83]  W. Busse,et al.  Detection of rhinovirus RNA in lower airway cells during experimentally induced infection. , 1997, American journal of respiratory and critical care medicine.

[84]  S. Johnston,et al.  Rhinoviruses induce interleukin-8 mRNA and protein production in human monocytes. , 1997, The Journal of infectious diseases.

[85]  W. Doyle,et al.  Prechallenge Antibodies: Moderators of Infection Rate, Signs, and Symptoms in Adults Experimentally Challenged With Rhinovirus Type 39 , 1996, The Laryngoscope.

[86]  M J Campbell,et al.  The relationship between upper respiratory infections and hospital admissions for asthma: a time-trend analysis. , 1996, American journal of respiratory and critical care medicine.

[87]  M. Jordana,et al.  CD40 expression by human peripheral blood eosinophils. , 1996, The Journal of clinical investigation.

[88]  W. Busse,et al.  Rhinovirus enters but does not replicate inside monocytes and airway macrophages. , 1996, Journal of immunology.

[89]  Joseph A. DiDonato,et al.  Immunosuppression by Glucocorticoids: Inhibition of NF-κB Activity Through Induction of IκB Synthesis , 1995, Science.

[90]  D. Proud,et al.  Infection of a human respiratory epithelial cell line with rhinovirus. Induction of cytokine release and modulation of susceptibility to infection by cytokine exposure. , 1995, The Journal of clinical investigation.

[91]  W. Doyle,et al.  Effect of rhinovirus 39 (RV‐39) infection on immune and inflammatory parameters in allergic and non‐allergic subjects , 1995, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

[92]  P. Heymann,et al.  Assessment of eosinophils, viruses and IgE antibody in wheezing infants and children. , 1995, International archives of allergy and immunology.

[93]  Kwang Woo Kim,et al.  Prominent neutrophilic inflammation in sputum from subjects with asthma exacerbation. , 1995, The Journal of allergy and clinical immunology.

[94]  S. Johnston,et al.  Lower airways inflammation during rhinovirus colds in normal and in asthmatic subjects. , 1995, American journal of respiratory and critical care medicine.

[95]  M. Karin,et al.  Immunosuppression by glucocorticoids: inhibition of NF-kappa B activity through induction of I kappa B synthesis. , 1995, Science.

[96]  J. Nadel,et al.  Cystic fibrosis sputum induces a secretory response from airway gland serous cells that can be prevented by neutrophil protease inhibitors. , 1995, The European respiratory journal.

[97]  C. Hawrylowicz,et al.  Synergy between dexamethasone and interleukin-5 for the induction of major histocompatibility complex class II expression by human peripheral blood eosinophils. , 1994, Blood.

[98]  S. Johnston,et al.  Amplified rhinovirus colds in atopic subjects , 1994, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

[99]  J. Kazura,et al.  Human eosinophils as antigen-presenting cells: relative efficiency for superantigen- and antigen-induced CD4+ T-cell proliferation. , 1994, Immunology.

[100]  E. Kuechler,et al.  Members of the low density lipoprotein receptor family mediate cell entry of a minor-group common cold virus. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[101]  P. Henricks,et al.  Expression and modulation of adhesion molecules on human bronchial epithelial cells. , 1993, American journal of respiratory cell and molecular biology.

[102]  K. Nicholson,et al.  Respiratory viruses and exacerbations of asthma in adults. , 1993, BMJ.

[103]  F. Hayden,et al.  Risk factors for acute wheezing in infants and children: viruses, passive smoke, and IgE antibodies to inhalant allergens. , 1993, Pediatrics.

[104]  D. Goeddel,et al.  Human macrophage inflammatory protein alpha (MIP-1 alpha) and MIP-1 beta chemokines attract distinct populations of lymphocytes , 1993, The Journal of experimental medicine.

[105]  D. Wong,et al.  Accessory cell function of human eosinophils. HLA-DR-dependent, MHC-restricted antigen-presentation and IL-1 alpha expression. , 1993, Journal of immunology.

[106]  W. Busse,et al.  Comparison of airway and blood eosinophil function after in vivo antigen challenge. , 1992, Journal of immunology.

[107]  J. Braunstein,et al.  Sputum eosinophils from asthmatics express ICAM‐1 and HLA‐DR , 1991, Clinical and experimental immunology.

[108]  P. Lewi,et al.  Two groups of rhinoviruses revealed by a panel of antiviral compounds present sequence divergence and differential pathogenicity , 1990, Journal of virology.

[109]  A. Cerami,et al.  Macrophage inflammatory proteins 1 and 2: members of a novel superfamily of cytokines , 1989, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[110]  F. Hayden,et al.  Ineffectiveness of Recombinant Interferon-βserine Nasal Drops for Prophylaxis of Natural Colds , 1989, The Journal of infectious diseases.

[111]  F. Hayden,et al.  Comparative Susceptibility of Respiratory Viruses to Recombinant Interferons-α2b and -β , 1989 .

[112]  C. Smith,et al.  Cooperative interactions of LFA-1 and Mac-1 with intercellular adhesion molecule-1 in facilitating adherence and transendothelial migration of human neutrophils in vitro. , 1989, The Journal of clinical investigation.

[113]  A. Mcclelland,et al.  The major human rhinovirus receptor is ICAM-1 , 1989, Cell.

[114]  Daniel Lucey,et al.  Mature human eosinophils have the capacity to express HLA-DR. , 1989, Proceedings of the National Academy of Sciences of the United States of America.

[115]  F. Hayden,et al.  Comparative susceptibility of respiratory viruses to recombinant interferons-alpha 2b and -beta. , 1989, Journal of interferon research.

[116]  F. Hayden,et al.  Modification of experimental rhinovirus colds by receptor blockade. , 1988, Antiviral research.

[117]  L. Lands,et al.  Childhood asthma: prevention of attacks with short-term corticosteroid treatment of upper respiratory tract infection. , 1988, Pediatrics.

[118]  G. Jackson,et al.  Acute-phase decrease of T lymphocyte subsets in rhinovirus infection. , 1986, The Journal of infectious diseases.

[119]  F. Hayden,et al.  Prevention of natural colds by contact prophylaxis with intranasal alpha 2-interferon. , 1986, The New England journal of medicine.

[120]  H. F. Bowman,et al.  Thermal mapping of the airways in humans. , 1985, Journal of applied physiology.

[121]  F. Hayden,et al.  Intranasal interferon-alpha 2 for prevention of natural rhinovirus colds , 1984, Antimicrobial Agents and Chemotherapy.

[122]  D. Wong,et al.  The development of respiratory syncytial virus-specific IgE and the release of histamine in nasopharyngeal secretions after infection. , 1981, The New England journal of medicine.