gamma-inducible protein-16; IL – interleukin; IL-1R1 – interleukin-1 receptor 1; MyD88 – myeloid differentiation factor 88; NF-B – nuclear factor of kappa light polypeptide gene enhancer in B-cells; NLR – NOD-like leucine-rich repeat-containing receptor; NOD – nucleotide oligomerization domain; PIA