Unique molecular signatures sustained in circulating monocytes and regulatory T cells in convalescent COVID-19 patients

[1]  S. Teichmann,et al.  Local and systemic responses to SARS-CoV-2 infection in children and adults , 2021, Nature.

[2]  S. Perlman,et al.  Immune dysregulation and immunopathology induced by SARS-CoV-2 and related coronaviruses — are we our own worst enemy? , 2021, Nature Reviews Immunology.

[3]  Jessica K. Fiege,et al.  Genetic ancestry effects on the response to viral infection are pervasive but cell type specific , 2021, Science.

[4]  S. Perlman,et al.  Immune dysregulation and immunopathology induced by SARS-CoV-2 and related coronaviruses — are we our own worst enemy? , 2021, Nature reviews. Immunology.

[5]  Yujia Yuan,et al.  Regulatory T cells in COVID-19 , 2021, Aging and disease.

[6]  Yong He,et al.  Symptoms and Health Outcomes Among Survivors of COVID-19 Infection 1 Year After Discharge From Hospitals in Wuhan, China , 2021, JAMA network open.

[7]  J. Geddes,et al.  Incidence, co-occurrence, and evolution of long-COVID features: A 6-month retrospective cohort study of 273,618 survivors of COVID-19 , 2021, PLoS medicine.

[8]  Sierra M. Barone,et al.  Single-Cell Profiling of the Antigen-Specific Response to BNT162b2 SARS-CoV-2 RNA Vaccine , 2021, bioRxiv.

[9]  Jonathan S. Packer,et al.  Embryo-scale, single-cell spatial transcriptomics , 2021, Science.

[10]  Kenneth G. C. Smith,et al.  Longitudinal analysis reveals that delayed bystander CD8+ T cell activation and early immune pathology distinguish severe COVID-19 from mild disease , 2021, Immunity.

[11]  André F. Rendeiro,et al.  A molecular single-cell lung atlas of lethal COVID-19 , 2021, Nature.

[12]  Frances E. Muldoon,et al.  Single-cell multi-omics analysis of the immune response in COVID-19 , 2021, Nature Medicine.

[13]  Md. Sahidul Islam,et al.  The role of CD4+FoxP3+ regulatory T cells in the immunopathogenesis of COVID-19: implications for treatment , 2021, International journal of biological sciences.

[14]  M. Raftery,et al.  SARS-CoV-2 in severe COVID-19 induces a TGF-β-dominated chronic immune response that does not target itself , 2021, Nature Communications.

[15]  D. Altmann,et al.  Risk of SARS-CoV-2 reinfection after natural infection , 2021, The Lancet.

[16]  T. van der Poll,et al.  Integrated single-cell analysis unveils diverging immune features of COVID-19, influenza, and other community-acquired pneumonia , 2021, eLife.

[17]  J. Schultze,et al.  COVID-19 and the human innate immune system , 2021, Cell.

[18]  Amit A. Patel,et al.  Monocytes, macrophages, dendritic cells and neutrophils: an update on lifespan kinetics in health and disease , 2021, Immunology.

[19]  Helio T. Navarro,et al.  Circuits between infected macrophages and T cells in SARS-CoV-2 pneumonia , 2020, Nature.

[20]  Ryan J. Low,et al.  Characterizing long COVID in an international cohort: 7 months of symptoms and their impact , 2020, EClinicalMedicine.

[21]  N. Marquardt,et al.  Distinct developmental pathways from blood monocytes generate human lung macrophage diversity. , 2020, Immunity.

[22]  T. Lancet Facing up to long COVID , 2020, The Lancet.

[23]  B. Walker,et al.  Profound Treg perturbations correlate with COVID-19 severity , 2020, bioRxiv.

[24]  C. Scottà,et al.  Treg cell therapy: How cell heterogeneity can make the difference , 2020, European journal of immunology.

[25]  B. Mustanski,et al.  Patterns and persistence of SARS-CoV-2 IgG antibodies in Chicago to monitor COVID-19 exposure , 2020, medRxiv.

[26]  Shuyang Zhang,et al.  IP-10 and MCP-1 as biomarkers associated with disease severity of COVID-19 , 2020, Molecular medicine.

[27]  Raphael Gottardo,et al.  Integrated analysis of multimodal single-cell data , 2020, Cell.

[28]  F. Callard,et al.  How and why patients made Long Covid , 2020, Social Science & Medicine.

[29]  A. Sette,et al.  Imbalance of Regulatory and Cytotoxic SARS-CoV-2-Reactive CD4+ T Cells in COVID-19 , 2020, Cell.

[30]  Jacques Fellay,et al.  Inborn errors of type I IFN immunity in patients with life-threatening COVID-19 , 2020, Science.

[31]  Madeleine K. D. Scott,et al.  Systems biological assessment of immunity to mild versus severe COVID-19 infection in humans , 2020, Science.

[32]  Alexander Sczyrba,et al.  Severe COVID-19 Is Marked by a Dysregulated Myeloid Cell Compartment , 2020, Cell.

[33]  C. von Kalle,et al.  COVID-19 severity correlates with airway epithelium–immune cell interactions identified by single-cell analysis , 2020, Nature Biotechnology.

[34]  Henghui Zhang,et al.  VEGF-D: a novel biomarker for detection of COVID-19 progression , 2020, Critical Care.

[35]  S. Tavakolpour,et al.  Lymphopenia during the COVID-19 infection: What it shows and what can be learned , 2020, Immunology Letters.

[36]  Aaron J. Wilk,et al.  A single-cell atlas of the peripheral immune response in patients with severe COVID-19 , 2020, Nature Medicine.

[37]  B. Mustanski,et al.  High seroprevalence for SARS-CoV-2 among household members of essential workers detected using a dried blood spot assay , 2020, medRxiv.

[38]  C. Cunningham-Rundles,et al.  A serological assay to detect SARS-CoV-2 seroconversion in humans , 2020, Nature Medicine.

[39]  I. Amit,et al.  Host-Viral Infection Maps Reveal Signatures of Severe COVID-19 Patients , 2020, Cell.

[40]  M. Dominguez-Villar,et al.  Modulation of regulatory T cell function and stability by co-inhibitory receptors , 2020, Nature Reviews Immunology.

[41]  Philip L. Felgner,et al.  A serological assay to detect SARS-CoV-2 seroconversion in humans , 2020, medRxiv.

[42]  Nicholas C. Wu,et al.  A highly conserved cryptic epitope in the receptor binding domains of SARS-CoV-2 and SARS-CoV , 2020, Science.

[43]  D. Shevyrev,et al.  Treg Heterogeneity, Function, and Homeostasis , 2020, Frontiers in Immunology.

[44]  H. Chi,et al.  Metabolic Control of Treg Cell Stability, Plasticity, and Tissue-Specific Heterogeneity , 2019, Front. Immunol..

[45]  J. Vilo,et al.  g:Profiler: a web server for functional enrichment analysis and conversions of gene lists (2019 update) , 2019, Nucleic Acids Res..

[46]  S. Sakaguchi,et al.  Human FOXP3+ Regulatory T Cell Heterogeneity and Function in Autoimmunity and Cancer. , 2019, Immunity.

[47]  Andrew J. Hill,et al.  The single cell transcriptional landscape of mammalian organogenesis , 2019, Nature.

[48]  Inna Kuperstein,et al.  Fibroblast Heterogeneity and Immunosuppressive Environment in Human Breast Cancer. , 2018, Cancer cell.

[49]  J. Borghans,et al.  Circulatory and maturation kinetics of human monocyte subsets in vivo. , 2017, Blood.

[50]  Hannah A. Pliner,et al.  Reversed graph embedding resolves complex single-cell trajectories , 2017, Nature Methods.

[51]  Amit A. Patel,et al.  The fate and lifespan of human monocyte subsets in steady state and systemic inflammation , 2017, The Journal of experimental medicine.

[52]  A. Rudensky,et al.  A Distinct Function of Regulatory T Cells in Tissue Protection , 2015, Cell.

[53]  C. Benoist,et al.  Treg cells expressing the coinhibitory molecule TIGIT selectively inhibit proinflammatory Th1 and Th17 cell responses. , 2014, Immunity.

[54]  Cole Trapnell,et al.  The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells , 2014, Nature Biotechnology.

[55]  E. Gratton,et al.  IFITM Proteins Restrict Viral Membrane Hemifusion , 2013, PLoS pathogens.

[56]  B. Grubeck‐Loebenstein,et al.  Imbalance of regulatory T cells in human autoimmune diseases , 2006, Immunology.

[57]  Alan S. Perelson,et al.  Increased Turnover of T Lymphocytes in HIV-1 Infection and Its Reduction by Antiretroviral Therapy , 2001, The Journal of experimental medicine.

[58]  S. Pocock,et al.  Incidence , , 2018 .