Genetic analysis of vertebral trabecular bone density and cross-sectional area in older men

[1]  D. Kiel,et al.  Collaborative Meta-analysis: Associations of 150 Candidate Genes With Osteoporosis and Osteoporotic Fracture , 2009, Annals of Internal Medicine.

[2]  Yurii S. Aulchenko,et al.  Twenty bone mineral density loci identified by large-scale meta-analysis of genome-wide association studies , 2009, Nature Genetics.

[3]  Yan Guo,et al.  Genome-wide association and follow-up replication studies identified ADAMTS18 and TGFBR3 as bone mass candidate genes in different ethnic groups. , 2009, American journal of human genetics.

[4]  Bjarni V. Halldórsson,et al.  New sequence variants associated with bone mineral density , 2009, Nature Genetics.

[5]  D. Karasik,et al.  Contribution of Gender‐Specific Genetic Factors to Osteoporosis Risk , 2008, Annals of human genetics.

[6]  P. Kostenuik,et al.  Targeted Deletion of the Sclerostin Gene in Mice Results in Increased Bone Formation and Bone Strength , 2008, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[7]  A Hofman,et al.  Bone mineral density, osteoporosis, and osteoporotic fractures: a genome-wide association study , 2008, The Lancet.

[8]  David M. Evans,et al.  Genome-wide association analysis identifies 20 loci that influence adult height , 2008, Nature Genetics.

[9]  David J J de Gorter,et al.  Osteocyte-derived sclerostin inhibits bone formation: its role in bone morphogenetic protein and Wnt signaling. , 2008, The Journal of bone and joint surgery. American volume.

[10]  M. Passos-Bueno,et al.  Genetics of craniosynostosis: genes, syndromes, mutations and genotype-phenotype correlations. , 2008, Frontiers of oral biology.

[11]  P. Marie,et al.  Roles of FGFR2 and twist in human craniosynostosis: insights from genetic mutations in cranial osteoblasts. , 2008, Frontiers of oral biology.

[12]  C. Bunker,et al.  Pleiotropy and Heterogeneity in the Expression of Bone Strength‐Related Phenotypes in Extended Pedigrees , 2007, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[13]  Zhaohui S. Qin,et al.  A second generation human haplotype map of over 3.1 million SNPs , 2007, Nature.

[14]  L. Bonewald,et al.  DMP1 and MEPE expression are elevated in osteocytes after mechanical loading in vivo: theoretical role in controlling mineral quality in the perilacunar matrix. , 2007, Journal of musculoskeletal & neuronal interactions.

[15]  Ji Young Kim,et al.  Association between an AluI Polymorphism in the Calcitonin Receptor Gene and Quantitative Ultrasound Parameters in Korean Men , 2007, Medical Principles and Practice.

[16]  M. Buckingham.  Skeletal muscle progenitor cells and the role of Pax genes. , 2007, Comptes rendus biologies.

[17]  C. Bunker,et al.  Genetic and Environmental Determinants of Volumetric and Areal BMD in Multi‐Generational Families of African Ancestry: The Tobago Family Health Study , 2007, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[18]  M. Peacock,et al.  Effect of osteoarthritis in the lumbar spine and hip on bone mineral density and diagnosis of osteoporosis in elderly men and women , 2007, Osteoporosis International.

[19]  J. Riancho,et al.  Association of the F352V variant of the Klotho gene with bone mineral density , 2007, Biogerontology.

[20]  J. Riancho,et al.  Klotho Gene Polymorphism and Male Bone Mass , 2007, Calcified Tissue International.

[21]  K. Ensrud,et al.  Dimensions and Volumetric BMD of the Proximal Femur and Their Relation to Age Among Older U.S. Men , 2006, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[22]  D. Reich,et al.  Principal components analysis corrects for stratification in genome-wide association studies , 2006, Nature Genetics.

[23]  P. Szulc.  Bone density, geometry, and fracture in elderly men , 2006, Current osteoporosis reports.

[24]  M. Cohen.  Role of leptin in regulating appetite, neuroendocrine function, and bone remodeling , 2006, American journal of medical genetics. Part A.

[25]  R. Baron,et al.  Wnt signaling: a key regulator of bone mass. , 2006, Current topics in developmental biology.

[26]  S. Cummings,et al.  Design and baseline characteristics of the osteoporotic fractures in men (MrOS) study--a large observational study of the determinants of fracture in older men. , 2005, Contemporary clinical trials.

[27]  P. Cawthon,et al.  Overview of recruitment for the osteoporotic fractures in men study (MrOS). , 2005, Contemporary clinical trials.

[28]  P. ten Dijke,et al.  SOST/sclerostin, an osteocyte-derived negative regulator of bone formation. , 2005, Cytokine & growth factor reviews.

[29]  W. Van Hul,et al.  A generalized skeletal hyperostosis in two siblings caused by a novel mutation in the SOST gene. , 2005, Bone.

[30]  D. Ovcharenko,et al.  Genomic deletion of a long-range bone enhancer misregulates sclerostin in Van Buchem disease. , 2005, Genome research.

[31]  Kathryn Roeder,et al.  Analysis of single‐locus tests to detect gene/disease associations , 2005, Genetic epidemiology.

[32]  E. Bandrés,et al.  Association between bone mineral density and polymorphisms of the VDR, ERα, COL1A1 and CTR genes in Spanish postmenopausal women , 2005 .

[33]  P. Leung,et al.  Molecular biology of gonadotropin-releasing hormone (GnRH)-I, GnRH-II, and their receptors in humans. , 2005, Endocrine reviews.

[34]  C. Wu,et al.  Spinal bone mineral assessment in postmenopausal women: A comparison between dual X-ray absorptiometry and quantitative computed tomography , 2005, Osteoporosis International.

[35]  A. Uitterlinden,et al.  Polymorphisms in the sclerosteosis/van Buchem disease gene (SOST) region are associated with bone-mineral density in elderly whites. , 2004, American journal of human genetics.

[36]  K. Lohman,et al.  Heritability of Spinal Trabecular Volumetric Bone Mineral Density Measured by QCT in the Diabetes Heart Study , 2004, Calcified Tissue International.

[37]  H. Genant,et al.  Cortical and Trabecular Bone Mineral Loss From the Spine and Hip in Long‐Duration Spaceflight , 2004, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[38]  C. Colnot,et al.  Mepe is expressed during skeletal development and regeneration , 2004, Histochemistry and Cell Biology.

[39]  G. Churchill,et al.  Mapping Quantitative Trait Loci for Vertebral Trabecular Bone Volume Fraction and Microarchitecture in Mice , 2003, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[40]  Yoshiji Yamada,et al.  Association of polymorphisms of the androgen receptor and klotho genes with bone mineral density in Japanese women , 2004, Journal of Molecular Medicine.

[41]  Toshihiro Tanaka.  The International HapMap Project , 2003, Nature.

[42]  M. Hill,et al.  Does polymorphism C1377T of the calcitonin receptor gene determine bone mineral density in postmenopausal women? , 2003, Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association.

[43]  M. Stephens,et al.  Inference of population structure using multilocus genotype data: linked loci and correlated allele frequencies. , 2003, Genetics.

[44]  S. Mohan,et al.  Quantitative trait loci for periosteal circumference (PC): identification of single loci and epistatic effects in F2 MRL/SJL mice. , 2003, Bone.

[45]  F. Tsai,et al.  The AluI Calcitonin Receptor Gene Polymorphism (TT) Is Associated with Low Bone Mineral Density and Susceptibility to Osteoporosis in Postmenopausal Women , 2003, Gynecologic and Obstetric Investigation.

[46]  J. Way,et al.  In vitro characterization of a human calcitonin receptor gene polymorphism. , 2003, Mutation research.

[47]  J. Stock,et al.  Targeted Disruption of the Osteoblast/Osteocyte Factor 45 Gene (OF45) Results in Increased Bone Formation and Bone Mass* , 2003, The Journal of Biological Chemistry.

[48]  Xuebin B. Yang,et al.  Induction of Human Osteoprogenitor Chemotaxis, Proliferation, Differentiation, and Bone Formation by Osteoblast Stimulating Factor‐1/Pleiotrophin: Osteoconductive Biomimetic Scaffolds for Tissue Engineering , 2003, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[49]  T. Ogihara,et al.  Matrix extracellular phosphoglycoprotein (MEPE) is highly expressed in osteocytes in human bone , 2003, Journal of Bone and Mineral Metabolism.

[50]  H. Roach,et al.  Pleiotrophin/Osteoblast‐Stimulating Factor 1: Dissecting Its Diverse Functions in Bone Formation , 2002, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[51]  T. Spector,et al.  Klotho Gene Polymorphisms Associated With Bone Density of Aged Postmenopausal Women , 2002, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[52]  E. Orwoll,et al.  Mapping Quantitative Trait Loci That Influence Femoral Cross‐sectional Area in Mice , 2002, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[53]  S. Mohan,et al.  Genetic dissection of femur breaking strength in a large population (MRL/MpJ x SJL/J) of F2 Mice: single QTL effects, epistasis, and pleiotropy. , 2002, Genomics.

[54]  T. Lufkin,et al.  The Dlx5 and Dlx6 homeobox genes are essential for craniofacial, axial, and appendicular skeletal development. , 2002, Genes & development.

[55]  L. Donahue,et al.  Regulation of bone volume is different in the metaphyses of the femur and vertebra of C3H/HeJ and C57BL/6J mice. , 2002, Bone.

[56]  G A Churchill,et al.  Quantitative Trait Loci for Femoral and Lumbar Vertebral Bone Mineral Density in C57BL/6J and C3H/HeJ Inbred Strains of Mice , 2001, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[57]  T. Ogihara,et al.  Calcitonin Receptor Gene Polymorphism in Japanese Women: Correlation with Body Mass and Bone Mineral Density , 2001, Calcified Tissue International.

[58]  R Müller,et al.  Variation in Bone Biomechanical Properties, Microstructure, and Density in BXH Recombinant Inbred Mice , 2001, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[59]  L. Cardon,et al.  Association study designs for complex diseases , 2001, Nature Reviews Genetics.

[60]  R. Rivera-Gonzalez,et al.  Identification of Osteoblast/Osteocyte Factor 45 (OF45), a Bone-specific cDNA Encoding an RGD-containing Protein That Is Highly Expressed in Osteoblasts and Osteocytes* , 2000, The Journal of Biological Chemistry.

[61]  M. Kuro-o,et al.  Independent impairment of osteoblast and osteoclast differentiation in klotho mouse exhibiting low-turnover osteopenia. , 1999, The Journal of clinical investigation.

[62]  E. Seeman,et al.  Osteoporosis in Men , 1999, Osteoporosis International.

[63]  A. Jullienne,et al.  Calcitonin receptor polymorphism is associated with a decreased fracture risk in post-menopausal women. , 1998, Human molecular genetics.

[64]  M. Brandi,et al.  Polymorphisms of the calcitonin receptor gene are associated with bone mineral density in postmenopausal Italian women. , 1998, Biochemical and biophysical research communications.

[65]  K. Ajlouni,et al.  Congenital adrenal hyperplasia due to 11 -β-hydroxylase deficiency with skeletal abnormalities , 1996, Journal of endocrinological investigation.

[66]  M. Cecchini,et al.  Recent developments in the understanding of the pathophysiology of osteopetrosis. , 1996, European journal of endocrinology.

[67]  G. Guglielmi,et al.  Osteoporosis: diagnosis with lateral and posteroanterior dual x-ray absorptiometry compared with quantitative CT. , 1994, Radiology.

[68]  M. Ito,et al.  Relationship of osteophytes to bone mineral density and spinal fracture in men. , 1993, Radiology.

[69]  I. Reid,et al.  The influence of osteophytes and aortic calcification on spinal mineral density in postmenopausal women. , 1991, The Journal of clinical endocrinology and metabolism.

[70]  E. Orwoll,et al.  The impact of osteophytic and vascular calcifications on vertebral mineral density measurements in men. , 1990, The Journal of clinical endocrinology and metabolism.

[71]  H. Genant,et al.  Impact of marrow fat on accuracy of quantitative CT. , 1989, Journal of computer assisted tomography.