Heterogeneity of hepatitis B virus C-gene sequences: implications for amplification and sequencing.

[1]  H. Will,et al.  Hepatitis B virus genomes that cannot synthesize pre-S2 proteins occur frequently and as dominant virus populations in chronic carriers in Italy. , 1992, Virology.

[2]  S. Günther,et al.  Frequent and rapid emergence of mutated pre-C sequences in HBV from e-antigen positive carriers who seroconvert to anti-HBe during interferon treatment. , 1992, Virology.

[3]  H. Will,et al.  Sensitive method for identification of minor hepatitis B mutant viruses. , 1992, Virology.

[4]  H. Will,et al.  The position of heterologous epitopes inserted in hepatitis B virus core particles determines their immunogenicity , 1992, Journal of virology.

[5]  H. Thomas,et al.  The clinical significance of molecular variation within the hepatitis B virus genome , 1992, Hepatology.

[6]  O. Yokosuka,et al.  Variations in codons 84-101 in the core nucleotide sequence correlate with hepatocellular injury in chronic hepatitis B virus infection. , 1992, The Journal of clinical investigation.

[7]  T. Ishikawa,et al.  Detection of pre-C and core region mutants of hepatitis B virus in chronic hepatitis B virus carriers. , 1991, The Journal of clinical investigation.

[8]  F. Chisari,et al.  HLA class I-restricted human cytotoxic T cells recognize endogenously synthesized hepatitis B virus nucleocapsid antigen. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[9]  F. Chisari,et al.  Cytotoxic T lymphocytes recognize an HLA-A2-restricted epitope within the hepatitis B virus nucleocapsid antigen , 1991, The Journal of experimental medicine.

[10]  H. Will,et al.  Selection for a pre-C stop codon mutation in a hepatitis B virus variant with a pre-C initiation codon mutation during interferon treatment. , 1991, Journal of hepatology.

[11]  P. Scheuer,et al.  Classification of chronic viral hepatitis: a need for reassessment. , 1991, Journal of hepatology.

[12]  U. Spengler,et al.  Hepatitis B virus antigen-specific T-cell activation in patients with acute and chronic hepatitis B. , 1991, Journal of hepatology.

[13]  A. Alberti,et al.  Hepatitis viruses as aetiological agents of hepatocellular carcinoma. , 1991, The Italian journal of gastroenterology.

[14]  T. Santantonio,et al.  Conserved core protein sequences in hepatitis B virus infected patients without anti-HBc. , 1991, Journal of Hepatology.

[15]  H. Will,et al.  Prevalence and type of pre-C HBV mutants in anti-HBe positive carriers with chronic liver disease in a highly endemic area. , 1991, Virology.

[16]  D. Shafritz.  Variants of hepatitis B virus associated with fulminant liver disease. , 1991, The New England journal of medicine.

[17]  H. Thomas,et al.  Genetically defined variants of hepatitis B virus , 1991 .

[18]  H. Will,et al.  Hepatitis B virus unable to secrete e antigen. , 1991, Gastroenterology.

[19]  J. Wands,et al.  Naturally occurring missense mutation in the polymerase gene terminating hepatitis B virus replication , 1991, Journal of virology.

[20]  T. Stijnen,et al.  Treatment of chronic viral hepatitis. , 1989, Digestive diseases.

[21]  Rogler Ce.  Cellular and molecular mechanisms of hepatocarcinogenesis associated with hepadnavirus infection. , 1991 .

[22]  H. Will,et al.  Latency and reactivation of a precore mutant hepatitis B virus in a chronically infected patient. , 1990, Journal of hepatology.

[23]  A. Zuckerman,et al.  Vaccine-induced escape mutant of hepatitis B virus , 1990, The Lancet.

[24]  R. Miller,et al.  Heterogeneity of the core gene sequence in a patient chronically infected with hepatitis B virus. , 1989, The Journal of infectious diseases.

[25]  R. Burk,et al.  Interrupted replication of hepatitis B virus in liver tissue of HBsAg carriers with hepatocellular carcinoma. , 1988, Virology.

[26]  C. Ferrari,et al.  Cellular immune response to hepatitis B virus antigens. An overview. , 1988, Journal of hepatology.

[27]  R. Palmiter,et al.  Structural and pathological effects of synthesis of hepatitis B virus large envelope polypeptide in transgenic mice. , 1987, Proceedings of the National Academy of Sciences of the United States of America.

[28]  H. Okamoto,et al.  Genomic heterogeneity of hepatitis B virus in a 54-year-old woman who contracted the infection through materno-fetal transmission. , 1987, The Japanese journal of experimental medicine.

[29]  H. Okamoto,et al.  Defective mutants of hepatitis B virus in the circulation of symptom-free carriers. , 1987, The Japanese journal of experimental medicine.

[30]  W. Rutter,et al.  Hepatitis B virus gene function: the precore region targets the core antigen to cellular membranes and causes the secretion of the e antigen. , 1986, Proceedings of the National Academy of Sciences of the United States of America.

[31]  Portland Press Ltd.  Nomenclature Committee for the International Union of Biochemistry (NC-IUB). Nomenclature for incompletely specified bases in nucleic acid sequences. Recommendations 1984. , 1985, Molecular biology and evolution.

[32]  A. Cornish-Bowden.  Nomenclature for incompletely specified bases in nucleic acid sequences: recommendations 1984. , 1985, Nucleic acids research.

[33]  J. Devereux,et al.  A comprehensive set of sequence analysis programs for the VAX , 1984, Nucleic Acids Res..

[34]  J. Hoofnagle,et al.  Viral hepatitis and liver disease , 1984 .

[35]  W. Rutter,et al.  THE NUCLEOTIDE SEQUENCE OF THE HEPATITIS B VIRAL GENOME AND THE IDENTIFICATION OF THE MAJOR VIRAL GENES , 1980 .

[36]  Walter Gilbert,et al.  Hepatitis B virus genes and their expression in E. coli , 1979, Nature.

[37]  F. Galibert,et al.  Nucleotide sequence of the hepatitis B virus genome (subtype ayw) cloned in E. coli , 1979, Nature.