Low oxygen tension stimulates the redifferentiation of dedifferentiated adult human nasal chondrocytes.

[1]  J. Tramper,et al.  Oxygen gradients in tissue‐engineered Pegt/Pbt cartilaginous constructs: Measurement and modeling , 2004, Biotechnology and bioengineering.

[2]  Clemens A van Blitterswijk,et al.  Cartilage Tissue Engineering: Controversy in the Effect of Oxygen , 2003, Critical reviews in biotechnology.

[3]  Ingo Klimant,et al.  Determination of oxygen gradients in engineered tissue using a fluorescent sensor. , 2002, Biotechnology and bioengineering.

[4]  Ivan Martin,et al.  Three-dimensional tissue engineering of hyaline cartilage: comparison of adult nasal and articular chondrocytes. , 2002, Tissue engineering.

[5]  J. Verhaar,et al.  Serum-free medium supplemented with high-concentration FGF2 for cell expansion culture of human ear chondrocytes promotes redifferentiation capacity. , 2002, Tissue engineering.

[6]  C. L. Murphy,et al.  Effect of oxygen tension and alginate encapsulation on restoration of the differentiated phenotype of passaged chondrocytes. , 2001, Tissue engineering.

[7]  J. Hassenpflug,et al.  Combination of reduced oxygen tension and intermittent hydrostatic pressure: a useful tool in articular cartilage tissue engineering. , 2001, Journal of biomechanics.

[8]  R. Mason,et al.  Modulation of bovine articular chondrocyte gene expression in vitro by oxygen tension. , 2001, Osteoarthritis and cartilage.

[9]  J. Verhaar,et al.  Monoclonal antibody 11-fibrau: a useful marker to characterize chondrocyte differentiation stage. , 2001, Biochemical and biophysical research communications.

[10]  R. Mason,et al.  Bovine articular chondrocyte function in vitro depends upon oxygen tension. , 2000, Osteoarthritis and cartilage.

[11]  J. Glowacki.  In vitro engineering of cartilage. , 2000, Journal of rehabilitation research and development.

[12]  V. Falanga,et al.  The levels and kinetics of oxygen tension detectable at the surface of human dermal fibroblast cultures , 2000, Journal of cellular physiology.

[13]  M. Schünke,et al.  [Redifferentiation of dedifferentiated joint cartilage cells in alginate culture. Effect of intermittent hydrostatic pressure and low oxygen partial pressure]. , 2000, Der Orthopade.

[14]  G. Vunjak‐Novakovic,et al.  Gas exchange is essential for bioreactor cultivation of tissue engineered cartilage. , 1999, Biotechnology and bioengineering.

[15]  H. J. Mankin,et al.  Instructional Course Lectures, The American Academy of Orthopaedic Surgeons - Articular Cartilage. Part II: Degeneration and Osteoarthrosis, Repair, Regeneration, and Transplantation*† , 1997 .

[16]  C. Koch,et al.  Adaptation of chondrocytes to low oxygen tension: Relationship between hypoxia and cellular metabolism , 1996, Journal of cellular physiology.

[17]  E. Kastenbauer,et al.  Influence of Chemical Allograft Preservation Procedures on the Human Immunodeficiency Virus , 1996, The Laryngoscope.

[18]  E. Hunziker,et al.  Repair of Partial-Thickness Defects in Articular Cartilage: Cell Recruitment from the Synovial Membrane* , 1996, The Journal of bone and joint surgery. American volume.

[19]  R. Mason,et al.  Responses of articular cartilage explant cultures to different oxygen tensions. , 1994, Biochimica et biophysica acta.

[20]  R. Mason,et al.  The relationship between proteoglycan synthesis in Swarm chondrocytes and pathways of cellular energy and UDP-sugar metabolism. , 1994, Carbohydrate research.

[21]  C. Brighton,et al.  The effect of oxygen tension on proteoglycan synthesis and aggregation in mammalian growth plate chondrocytes , 1991, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[22]  N. Kawabe,et al.  The repair of full-thickness articular cartilage defects. Immune responses to reparative tissue formed by allogeneic growth plate chondrocyte implants. , 1991, Clinical orthopaedics and related research.

[23]  M. Iwamoto,et al.  Terminal differentiation and calcification in rabbit chondrocyte cultures grown in centrifuge tubes: regulation by transforming growth factor beta and serum factors. , 1988, Proceedings of the National Academy of Sciences of the United States of America.

[24]  Y. Eilam,et al.  Slowing down aging of cultured embryonal chick chondrocytes by maintenance under lowered oxygen tension , 1988, Mechanisms of Ageing and Development.

[25]  F. Watt.  Effect of seeding density on stability of the differentiated phenotype of pig articular chondrocytes in culture. , 1988, Journal of cell science.

[26]  P. Kitos,et al.  Effects of molecular oxygen on chick limb bud chondrogenesis. , 1988, Differentiation; research in biological diversity.

[27]  D. Buttle,et al.  Improved quantitation and discrimination of sulphated glycosaminoglycans by use of dimethylmethylene blue. , 1986, Biochimica et biophysica acta.

[28]  David M. Ward,et al.  Oxygen Microelectrode That Is Insensitive to Medium Chemical Composition: Use in an Acid Microbial Mat Dominated by Cyanidium caldarium , 1983, Applied and environmental microbiology.

[29]  P. Benya,et al.  Dedifferentiated chondrocytes reexpress the differentiated collagen phenotype when cultured in agarose gels , 1982, Cell.

[30]  P. Benya,et al.  Independent regulation of collagen types by chondrocytes during the loss of differentiated function in culture , 1978, Cell.

[31]  Peter Müller,et al.  Relationship between cell shape and type of collagen synthesised as chondrocytes lose their cartilage phenotype in culture , 1977, Nature.

[32]  P. Benya,et al.  The progeny of rabbit articular chondrocytes synthesize collagen types I and III and type I trimer, but not type II. Verifications by cyanogen bromide peptide analysis. , 1977, Biochemistry.

[33]  Jayson Mi,et al.  Organ culture of adult human articular cartilage. I. The effect of hyperoxia on synthesis of glycosaminoglycan. , 1975 .

[34]  I. Silver.  Measurement of pH and ionic composition of pericellular sites. , 1975, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

[35]  H J Mankin,et al.  The reaction of articular cartilage to injury and osteoarthritis (second of two parts). , 1974, The New England journal of medicine.

[36]  C. Brighton,et al.  In vitro rabbit articular cartilage organ model. II. 35S incorporation in various oxygen tensions. , 1974, Arthritis and rheumatism.

[37]  Heppenstall Rb,et al.  Oxygen tension of the epiphyseal plate distal to an arteriovenous fistula. , 1971 .

[38]  C. Brighton,et al.  Oxygen tension in zones of the epiphyseal plate, the metaphysis and diaphysis. An in vitro and in vivo study in rats and rabbits. , 1971, The Journal of bone and joint surgery. American volume.

[39]  C. ANDREW L. BASSETT,et al.  Influence of Oxygen Concentration and Mechanical Factors on Differentiation of Connective Tissues in vitro , 1961, Nature.

[40]  B Kurz,et al.  Redifferentiation of dedifferentiated bovine articular chondrocytes in alginate culture under low oxygen tension. , 2002, Osteoarthritis and cartilage.

[41]  H. Mankin,et al.  The reaction of articular cartilage to injury and osteoarthritis (first of two parts). , 1974, The New England journal of medicine.

[42]  J. Pawelek.  Effects of thyroxine and low oxygen tension on chondrogenic expression in cell culture. , 1969, Developmental biology.