DNA dot‐blot hybridization implicates human papillomavirus type 11‐DNA in epithelioma cuniculatum

Epithelioma cuniculatum is a rare, low‐grade squamous cell carcinoma, belonging to the group of verrucous carcinomas. Evidence is presented that suggests that human papilloma virus type‐11 may be involved in the pathogenesis of epithelioma cuniculatum. HPV‐DNA was detected by dot‐blot hybridization with 32P‐labelled probe DNA. Plasmids containing HPV‐DNA were isolated by the benzoylated naphthoylated DEAE cellulose method (BND‐method), an improved procedure for routine detection of HPV‐DNA.

[1]  R. Rando.  Human papillomavirus: implications for clinical medicine. , 1988, Annals of internal medicine.

[2]  B. Coldiron,et al.  Epithelioma cuniculatum (carcinoma cuniculatum) of the thumb: a case report and literature review. , 1986, The Journal of dermatologic surgery and oncology.

[3]  A. Burkhardt.  [Verrucous carcinoma and carcinoma cuniculatum--forms of squamous cell carcinoma?]. , 1986, Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete.

[4]  E. Sánchez-Yus,et al.  Verrucous carcinoma of the back. , 1986, Journal of the American Academy of Dermatology.

[5]  L. Gissmann,et al.  Papillomavirus infection of the anogenital region: correlation between histology, clinical picture, and virus type. Proposal of a new nomenclature. , 1985, The Journal of investigative dermatology.

[6]  Barnett Jh,et al.  Multiple epitheliomata cuniculata occurring in a mutilating keratoderma. , 1985 .

[7]  N. Lehman,et al.  Purification of circular DNA using benzoylated naphthoylated DEAE-cellulose. , 1985, DNA.

[8]  H. Hausen,et al.  A new type of papillomavirus DNA, its presence in genital cancer biopsies and in cell lines derived from cervical cancer. , 1984, The EMBO journal.

[9]  R. Kuffer,et al.  [Buccopharyngeal localizations of carcinoma cuniculatum. Apropos of 5 cases]. , 1984, Archives d'anatomie et de cytologie pathologiques.

[10]  L. Gissmann,et al.  Human papillomavirus types 6 and 11 DNA sequences in genital and laryngeal papillomas and in some cervical cancers. , 1983, Proceedings of the National Academy of Sciences of the United States of America.

[11]  E. B. Helwig,et al.  Carcinoma cuniculatum (verrucous carcinoma of the skin): A clinicopathologic study of 46 cases with ultrastructural observations , 1982, Cancer.

[12]  E. Ratzenhofer.  [Epithelioma cuniculatum. A special form of verrucous carcinoma (author's transl)]. , 1982, Wiener klinische Wochenschrift.

[13]  E. de Villiers,et al.  Analysis of human genital warts (condylomata acuminata) and other genital tumors for human papillomavirus type 6 DNA , 1982 .

[14]  J. Wilkinson,et al.  Carcinoma (epithelioma) cuniculatum: a clinico‐pathological study of nineteen cases and review of the literature , 1981, Histopathology.

[15]  L. P. Souza,et al.  Epithelioma cuniculatum, a verrucous carcinoma of the foot. Report of 2 cases. , 1981, Dermatologica.

[16]  P. G. Prioleau,et al.  Verrucous carcinoma. A light and electron microscopic, autoradiographic, and immunofluorescence study , 1980, Cancer.

[17]  P. Jordan,et al.  Verrucous Carcinoma of Skin , 1980, Journal of cutaneous pathology.

[18]  J. Seehafer,et al.  Epithelioma cuniculatum: verrucous carcinoma of the foot. , 1979, Cutis.

[19]  L. Shapiro,et al.  Verrucous carcinoma of skin. Epithelioma cuniculatum plantare , 1976, Cancer.

[20]  G. Elliott,et al.  Problems of Verrucose Squamous Carcinoma , 1973, Annals of surgery.

[21]  B. Lennox,et al.  Epithelioma cuniculatum: a variety of squamous carcinoma peculiar to the foot. , 1954, The British journal of surgery.

[22]  W. F. Lever,et al.  Histopathology of the Skin , 1962 .

[23]  L. Ackerman.  Verrucous carcinoma of the oral cavity. , 1948, Surgery.