LMP1 signaling can replace CD40 signaling in B cells in vivo and has unique features of inducing class-switch recombination to IgG1.
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K. Rajewsky | U. Zimber-Strobl | Werner Müller | J. Seagal | A. Hermann | Julia Rastelli | Cornelia Hömig-Hölzel | U. Zimber-Strobl | Cornelia Hömig-Hölzel | Ursula Zimber-Strobl | Cornelia Hömig‐Hölzel
[1] K. Rajewsky,et al. IgG1 B cell receptor signaling is inhibited by CD22 and promotes the development of B cells whose survival is less dependent on Igα/β , 2007, The Journal of experimental medicine.
[2] G. Kollias,et al. Comparative Analysis of Signal Transduction by CD40 and the Epstein-Barr Virus Oncoprotein LMP1 In Vivo , 2004, Journal of Virology.
[3] G. Bishop,et al. Expression of the cytoplasmic tail of LMP1 in mice induces hyperactivation of B lymphocytes and disordered lymphoid architecture. , 2004, Immunity.
[4] B. Baban,et al. Expression of indoleamine 2,3-dioxygenase by plasmacytoid dendritic cells in tumor-draining lymph nodes. , 2004, The Journal of clinical investigation.
[5] P. Casali,et al. EBV-Encoded Latent Membrane Protein 1 Cooperates with BAFF/BLyS and APRIL to Induce T Cell-Independent Ig Heavy Chain Class Switching 1 , 2003, The Journal of Immunology.
[6] E. Kremmer,et al. TRAF6 is a critical mediator of signal transduction by the viral oncogene latent membrane protein 1 , 2001, The EMBO journal.
[7] D. Thorley-Lawson,et al. Epstein-Barr virus: exploiting the immune system , 2001, Nature Reviews Immunology.
[8] D. Thorley-Lawson,et al. The expression pattern of Epstein-Barr virus latent genes in vivo is dependent upon the differentiation stage of the infected B cell. , 2000, Immunity.
[9] K. Rajewsky,et al. EBV-infected B cells in infectious mononucleosis: viral strategies for spreading in the B cell compartment and establishing latency. , 2000, Immunity.
[10] E. Kieff,et al. The Residues between the Two Transformation Effector Sites of Epstein-Barr Virus Latent Membrane Protein 1 Are Not Critical for B-Lymphocyte Growth Transformation , 1999, Journal of Virology.
[11] N. Raab-Traub,et al. Mimicry of CD40 signals by Epstein-Barr virus LMP1 in B lymphocyte responses. , 1999, Science.
[12] E. Kieff,et al. The Epstein-Barr Virus Oncoprotein Latent Membrane Protein 1 Engages the Tumor Necrosis Factor Receptor-Associated Proteins TRADD and Receptor-Interacting Protein (RIP) but Does Not Induce Apoptosis or Require RIP for NF-κB Activation , 1999, Molecular and Cellular Biology.
[13] M. Ueffing,et al. Latent membrane protein 1 of Epstein–Barr virus interacts with JAK3 and activates STAT proteins , 1999, The EMBO journal.
[14] W. Hammerschmidt,et al. LMP1 signal transduction differs substantially from TNF receptor 1 signaling in the molecular functions of TRADD and TRAF2 , 1999, The EMBO journal.
[15] D. Thorley-Lawson,et al. EBV persistence in memory B cells in vivo. , 1998, Immunity.
[16] P. Thompson,et al. STAT6 is required for IL-4-induced germline Ig gene transcription and switch recombination. , 1998, Journal of immunology.
[17] W. Kolch,et al. Epstein–Barr virus latent membrane protein‐1 triggers AP‐1 activity via the c‐Jun N‐terminal kinase cascade , 1997, The EMBO journal.
[18] M. Ueffing,et al. Latent membrane protein 1 of Epstein–Barr virus mimics a constitutively active receptor molecule , 1997, The EMBO journal.
[19] M. Neuberger,et al. Rapid methods for the analysis of immunoglobulin gene hypermutation: application to transgenic and gene targeted mice. , 1997, Nucleic acids research.
[20] K. Rajewsky,et al. B lymphocyte-specific, Cre-mediated mutagenesis in mice. , 1997, Nucleic acids research.
[21] J. Banchereau,et al. Epstein‐Barr virus latent membrane protein (LMP1) is not sufficient to maintain proliferation of B cells but both it and activated CD40 can prolong their survival. , 1996, The EMBO journal.
[22] E. Kieff,et al. Identification of TRAF6, a Novel Tumor Necrosis Factor Receptor-associated Factor Protein That Mediates Signaling from an Amino-terminal Domain of the CD40 Cytoplasmic Region* , 1996, The Journal of Biological Chemistry.
[23] V. Diehl,et al. Promotion of IL8, IL10, TNFα and TNFβ production by EBV infection , 1996 .
[24] R. Flavell,et al. Mice deficient for the CD40 ligand. , 1994, Immunity.
[25] N. Yoshida,et al. The immune responses in CD40-deficient mice: impaired immunoglobulin class switching and germinal center formation. , 1994, Immunity.
[26] B. Mosinger,et al. Targeted oncogene activation by site-specific recombination in transgenic mice. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[27] J. Banchereau,et al. Growing human B lymphocytes in the CD40 system , 1991, Nature.
[28] J. Stavnezer,et al. Immunoglobulin heavy-chain switching may be directed by prior induction of transcripts from constant-region genes. , 1988, Proceedings of the National Academy of Sciences of the United States of America.
[29] B. Sugden,et al. CD40 and its viral mimic, LMP1: similar means to different ends. , 2003, Cellular signalling.
[30] E. Montecino-Rodriguez,et al. Bipotential B-macrophage progenitors are present in adult bone marrow , 2001, Nature Immunology.
[31] Philippe Soriano. Generalized lacZ expression with the ROSA26 Cre reporter strain , 1999, Nature Genetics.
[32] V. Diehl,et al. Promotion of IL8, IL10, TNF alpha and TNF beta production by EBV infection. , 1996, Leukemia research.