Contribution of morphological assessment of the vessel tree by three‐dimensional ultrasound to a correct diagnosis of malignancy in ovarian masses

To determine whether subjective evaluation of the morphology of the vessel tree of ovarian tumors, as depicted by three‐dimensional (3D) power Doppler ultrasound, can discriminate between benign and malignant ovarian tumors, and whether it improves characterization compared with using gray‐scale ultrasound imaging alone.

[1]  H. Zhang,et al.  Microvascular corrosion casting of normal tissue, transitional mucosa and adenocarcinoma in the human colon. , 1992, Acta oncologica.

[2]  I. Herman,et al.  Mechanisms of normal and tumor-derived angiogenesis. , 2002, American journal of physiology. Cell physiology.

[3]  S. Guerriero,et al.  Diagnosis of adnexal malignancies by using color Doppler energy imaging as a secondary test in persistent masses , 1998, Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology.

[4]  J. Yamate,et al.  Angioarchitecture of Tumors Induced by Two Different Cloned Cell Lines Established from a Transplantable Rat Malignant Fibrous Histiocytoma , 2003, Microscopy and Microanalysis.

[5]  F Tranquart,et al.  Power Doppler vascularity index for predicting malignancy of adnexal masses , 2005, Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology.

[6]  Sabine Van Huffel,et al.  External Validation of Mathematical Models to Distinguish Between Benign and Malignant Adnexal Tumors: A Multicenter Study by the International Ovarian Tumor Analysis Group , 2007, Clinical Cancer Research.

[7]  A. Staudach,et al.  Combined transvaginal B-mode and color Doppler sonography for differential diagnosis of ovarian tumors: results of a multivariate logistic regression analysis. , 2000, Gynecologic oncology.

[8]  R. Jain,et al.  Intussusceptive microvascular growth in a human colon adenocarcinoma xenograft: a novel mechanism of tumor angiogenesis. , 1996, Microvascular research.

[9]  L. Valentin,et al.  Pattern recognition of pelvic masses by gray‐scale ultrasound imaging: the contribution of Doppler ultrasound , 1999, Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology.

[10]  R K Jain,et al.  Determinants of tumor blood flow: a review. , 1988, Cancer research.

[11]  R. Jain,et al.  Fractal Characteristics of Tumor Vascular Architecture During Tumor Growth and Regression , 1997, Microcirculation.

[12]  S. Guerriero,et al.  Complex Pelvic Mass as a Target of Evaluation of Vessel Distribution by Color Doppler Sonography for the Diagnosis of Adnexal Malignancies , 2002, Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine.

[13]  A. Lindgren The vascular supply of tumours with special reference to the capillary angioarchitekture. , 2009, Acta pathologica et microbiologica Scandinavica.

[14]  K. Ranniger,et al.  Abdominal angiography. , 1968, Current problems in surgery.

[15]  S. Huffel,et al.  Which extrauterine pelvic masses are difficult to correctly classify as benign or malignant on the basis of ultrasound findings and is there a way of making a correct diagnosis? , 2006, Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology.

[16]  Jacob Cohen A Coefficient of Agreement for Nominal Scales , 1960 .

[17]  Piotr A Wielopolski,et al.  MR angiography of tumor-related vasculature: from the clinic to the micro-environment. , 2005, Radiographics : a review publication of the Radiological Society of North America, Inc.

[18]  J. Buy,et al.  Characterization of adnexal masses: combination of color Doppler and conventional sonography compared with spectral Doppler analysis alone and conventional sonography alone. , 1996, AJR. American journal of roentgenology.

[19]  J. Tyszka,et al.  Differentiation of benign and malignant adnexal masses: relative value of gray-scale, color Doppler, and spectral Doppler sonography. , 1995, AJR. American journal of roentgenology.

[20]  A. Paoletti,et al.  Ultrasonography and color Doppler-based triage for adnexal masses to provide the most appropriate surgical approach. , 2005, American journal of obstetrics and gynecology.

[21]  T-Y Lee,et al.  CT imaging of angiogenesis. , 2003, The quarterly journal of nuclear medicine : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology.

[22]  D. Timmerman,et al.  The Use of Contrasted Transvaginal Sonography in the Diagnosis of Gynecologic Diseases , 2005, Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine.

[23]  G. Jayson,et al.  Intra-tumoural microvessel density in human solid tumours , 2002, British Journal of Cancer.

[24]  K. Jonsson,et al.  Angiography of the Ovarian Artery in Adnexal Lesions , 1980, Acta radiologica: diagnosis.

[25]  S. Gabbe,et al.  Diagnostic tests in obstetrics: a method for improved evaluation. , 1985, American journal of obstetrics and gynecology.

[26]  A. Silman,et al.  Statistical methods for assessing observer variability in clinical measures. , 1992, BMJ.

[27]  R. Dodge,et al.  The prognostic significance of angiogenesis in epithelial ovarian carcinoma. , 1999, Clinical cancer research : an official journal of the American Association for Cancer Research.

[28]  L. Jokubkiene,et al.  Does three‐dimensional power Doppler ultrasound help in discrimination between benign and malignant ovarian masses? , 2007 .

[29]  J. Alcázar,et al.  Transvaginal color Doppler assessment of venous flow in adnexal masses , 2001, Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology.

[30]  W. Sauerbrei,et al.  Classification of adnexal tumors by transvaginal color Doppler. , 1996, Gynecologic oncology.

[31]  Brian J. Smith,et al.  The influence of microvessel density on ovarian carcinogenesis. , 2003, Gynecologic oncology.

[32]  H. Dvorak,et al.  Identification and characterization of the blood vessels of solid tumors that are leaky to circulating macromolecules. , 1988, The American journal of pathology.

[33]  S. Paku,et al.  First steps of tumor-related angiogenesis. , 1991, Laboratory investigation; a journal of technical methods and pathology.

[34]  L. Valentin Prospective cross‐validation of Doppler ultrasound examination and gray‐scale ultrasound imaging for discrimination of benign and malignant pelvic masses , 1999, Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology.

[35]  B. Mol,et al.  Distinguishing the benign and malignant adnexal mass: an external validation of prognostic models. , 2001, Gynecologic oncology.

[36]  K. Messmer,et al.  The fine structure of tumor blood vessels. I. Participation of non-endothelial cells in tumor angiogenesis. , 1985, International journal of microcirculation, clinical and experimental.

[37]  J. Shepherd Revised FIGO staging for gynaecological cancer , 1989, British journal of obstetrics and gynaecology.

[38]  Philippe Shubik,et al.  Vascularization of tumors: A review , 2004, Journal of Cancer Research and Clinical Oncology.

[39]  J. Folkman,et al.  ISOLATION OF A TUMOR FACTOR RESPONSIBLE FOR ANGIOGENESIS , 1971, The Journal of experimental medicine.

[40]  L. Valentin,et al.  Comparison of ‘pattern recognition’ and logistic regression models for discrimination between benign and malignant pelvic masses: a prospective cross validation , 2001, Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology.

[41]  T. Bourne,et al.  Terms, definitions and measurements to describe the sonographic features of adnexal tumors: a consensus opinion from the International Ovarian Tumor Analysis (IOTA) group , 2000, Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology.

[42]  M A Konerding,et al.  Microvascular corrosion casting in the study of tumor vascularity: a review. , 1995, Scanning microscopy.

[43]  M A Konerding,et al.  Evidence for characteristic vascular patterns in solid tumours: quantitative studies using corrosion casts , 1999, British Journal of Cancer.

[44]  L. Valentin,et al.  Does three‐dimensional power Doppler ultrasound help in discrimination between benign and malignant ovarian masses? , 2007, Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology.

[45]  J. Itoh,et al.  Three-dimensional imaging of tumor angiogenesis. , 2000, Analytical and quantitative cytology and histology.

[46]  H. Augustin,et al.  Heterogeneity of angiogenesis and blood vessel maturation in human tumors: implications for antiangiogenic tumor therapies. , 2000, Cancer research.

[47]  A. Miodoński,et al.  Angiomorphology of the human renal clear cell carcinoma , 1989, Virchows Archiv A.

[48]  D. Fishman,et al.  Three-dimensional power Doppler ultrasound improves the diagnostic accuracy for ovarian cancer prediction. , 2001, Gynecologic oncology.

[49]  G. Ferrandina,et al.  Does quantitative analysis of three‐dimensional power Doppler angiography have a role in the diagnosis of malignant pelvic solid tumors? A preliminary study , 2005, Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology.