A musculoskeletal model of the hand and wrist: model definition and evaluation

Abstract To improve our understanding on the neuromechanics of finger movements, a comprehensive musculoskeletal model is needed. The aim of this study was to build a musculoskeletal model of the hand and wrist, based on one consistent data set of the relevant anatomical parameters. We built and tested a model including the hand and wrist segments, as well as the muscles of the forearm and hand in OpenSim. In total, the model comprises 19 segments (with the carpal bones modeled as one segment) with 23 degrees of freedom and 43 muscles. All required anatomical input data, including bone masses and inertias, joint axis positions and orientations as well as muscle morphological parameters (i.e. PCSA, mass, optimal fiber length and tendon length) were obtained from one cadaver of which the data set was recently published. Model validity was investigated by first comparing computed muscle moment arms at the index finger metacarpophalangeal (MCP) joint and wrist joint to published reference values. Secondly, the muscle forces during pinching were computed using static optimization and compared to previously measured intraoperative reference values. Computed and measured moment arms of muscles at both index MCP and wrist showed high correlation coefficients (r = 0.88 averaged across all muscles) and modest root mean square deviation (RMSD = 23% averaged across all muscles). Computed extrinsic flexor forces of the index finger during index pinch task were within one standard deviation of previously measured in-vivo tendon forces. These results provide an indication of model validity for use in estimating muscle forces during static tasks.

[1]  S. Gandevia,et al.  Limited independent flexion of the thumb and fingers in human subjects. , 1994, The Journal of physiology.

[2]  J Mizrahi,et al.  A biomechanical model of index finger dynamics. , 1995, Medical engineering & physics.

[3]  Jae Kun Shim,et al.  Effect of Resistance Training of the Wrist Joint Muscles on Multi-Digit Coordination , 2015, Perceptual and motor skills.

[4]  K. An,et al.  Tendon excursion and moment arm of index finger muscles. , 1983, Journal of biomechanics.

[5]  K N An,et al.  Normative model of human hand for biomechanical analysis. , 1979, Journal of biomechanics.

[6]  M. Pandy,et al.  Sensitivity of model predictions of muscle function to changes in moment arms and muscle-tendon properties: a Monte-Carlo analysis. , 2012, Journal of biomechanics.

[7]  D. Jindrich,et al.  Finger Muscle Attachments for an OpenSim Upper-Extremity Model , 2015, PloS one.

[8]  Peter J Keir,et al.  Modelling tendon excursions and moment arms of the finger flexors: anatomic fidelity versus function. , 2011, Journal of biomechanics.

[9]  J. Fridén,et al.  Human wrist motors: biomechanical design and application to tendon transfers. , 1996, Journal of biomechanics.

[10]  Darshan Shah,et al.  Importance of Consistent Datasets in Musculoskeletal Modelling: A Study of the Hand and Wrist , 2017, Annals of Biomedical Engineering.

[11]  Sofiane Boudaoud,et al.  Proposition, identification, and experimental evaluation of an inverse dynamic neuromusculoskeletal model for the human finger , 2015, Comput. Biol. Medicine.

[12]  Ayman Habib,et al.  OpenSim: Open-Source Software to Create and Analyze Dynamic Simulations of Movement , 2007, IEEE Transactions on Biomedical Engineering.

[13]  T. Sandercock,et al.  Force Transmission between Synergistic Skeletal Muscles through Connective Tissue Linkages , 2010, Journal of biomedicine & biotechnology.

[14]  C. D. Mote,et al.  In vivo finger flexor tendon force while tapping on a keyswitch , 1999, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[15]  J L Sancho-Bru,et al.  A 3-D dynamic model of human finger for studying free movements. , 2001, Journal of biomechanics.

[16]  Paul W. Brand,et al.  Clinical mechanics of the hand , 1985 .

[17]  F. Zajac,et al.  Large index-fingertip forces are produced by subject-independent patterns of muscle excitation. , 1998, Journal of biomechanics.

[18]  D R Pichora,et al.  Simulation of extension, radial and ulnar deviation of the wrist with a rigid body spring model. , 2009, Journal of biomechanics.

[19]  Vasilios Baltzopoulos,et al.  In vivo measurements of muscle specific tension in adults and children , 2010, Experimental physiology.

[20]  Kai-Nan An,et al.  Modeling of the muscle/tendon excursions and moment arms in the thumb using the commercial software anybody. , 2009, Journal of biomechanics.

[21]  Zong-Ming Li.  The influence of wrist position on individual finger forces during forceful grip. , 2002, The Journal of hand surgery.

[22]  K. Kursa,et al.  In vivo forces generated by finger flexor muscles do not depend on the rate of fingertip loading during an isometric task. , 2005, Journal of biomechanics.

[23]  H. E. J. Veeger,et al.  Anatomical parameters for musculoskeletal modeling of the hand and wrist , 2016 .

[24]  Francisco J. Valero Cuevas,et al.  Slow Movements of Bio-Inspired Limbs , 2016, J. Nonlinear Sci..

[25]  T D Cahalan,et al.  The relationship between wrist position, grasp size, and grip strength. , 1992, The Journal of hand surgery.

[26]  K. An,et al.  Extensor mechanism of the fingers. I. A quantitative geometric study. , 1991, The Journal of hand surgery.

[27]  J N Leijnse,et al.  Connections between the tendons of the musculus flexor digitorum profundus involving the synovial sheaths in the carpal tunnel. , 1997, Acta anatomica.

[28]  R. Eaton.  The extensor mechanism of the fingers. , 1969, Bulletin of the Hospital for Joint Diseases.

[29]  R. Lieber,et al.  Architectural design of the human intrinsic hand muscles. , 1992, The Journal of hand surgery.

[30]  V M Zatsiorsky,et al.  The effect of finger extensor mechanism on the flexor force during isometric tasks. , 2001, Journal of biomechanics.

[31]  Eric Berton,et al.  Comparison of tendon tensions estimated from two biomechanical models of the thumb. , 2009, Journal of biomechanics.

[32]  G. Bain,et al.  The functional range of motion of the finger joints , 2015, The Journal of hand surgery, European volume.

[33]  Joseph D. Towles,et al.  Towards a realistic biomechanical model of the thumb: the choice of kinematic description may be more critical than the solution method or the variability/uncertainty of musculoskeletal parameters. , 2003, Journal of biomechanics.

[34]  Benjamin J. Majors,et al.  Development and Validation of a Computational Model for Investigation of Wrist Biomechanics , 2011, Annals of Biomedical Engineering.

[35]  Joseph D. Towles,et al.  Quantification of fingertip force reduction in the forefinger following simulated paralysis of extensor and intrinsic muscles. , 2000, Journal of biomechanics.

[36]  Ren G Dong,et al.  A practical biomechanical model of the index finger simulating the kinematics of the muscle/tendon excursions. , 2010, Bio-medical materials and engineering.

[37]  Zong-Ming Li.  The influence of wrist position on individual finger forces during forceful grip. , 2002, The Journal of hand surgery.

[38]  Francisco J Valero-Cuevas,et al.  An Integrative Approach to the Biomechanical Function and Neuromuscular Control of the Fingers , 2004 .

[39]  S. Seber,et al.  Normal Range of Motion of the Joints of the Upper Extremity in Male Subjects, with Special Reference to Side* , 1996, The Journal of bone and joint surgery. American volume.

[40]  M. Alamir,et al.  The biomechanical model of the long finger extensor mechanism and its parametric identification. , 2017, Journal of biomechanics.

[41]  F. Marin,et al.  Analysis of the musculoskeletal system of the hand and forearm during a cylinder grasping task , 2014 .

[42]  Antonio Morales,et al.  Grasp modelling with a biomechanical model of the hand , 2014, Computer methods in biomechanics and biomedical engineering.

[43]  Benjamin I Binder-Markey,et al.  Incorporating the length-dependent passive-force generating muscle properties of the extrinsic finger muscles into a wrist and finger biomechanical musculoskeletal model. , 2017, Journal of biomechanics.

[44]  Peter J Keir,et al.  An open-source model and solution method to predict co-contraction in the finger , 2017, Computer methods in biomechanics and biomedical engineering.

[45]  D. Pahr,et al.  The effect of the extensor mechanism on maximum isometric fingertip forces: A numerical study on the index finger. , 2016, Journal of biomechanics.