Residual Convolutional Neural Networks for Breast Density Classification

In this paper, we propose a data-driven method to classify mammograms according to breast density in BIRADS standard. About 2000 mammographic exams have been collected from the “Azienda OspedalieroUniversitaria Pisana” (AOUP, Pisa, IT). The dataset has been classified according to breast density in the BI-RADS standard. Once the dataset has been labeled by a radiologist, we proceeded by building a Residual Neural Network in order to classify breast density in two ways. First, we classified mammograms using two “super-classes” that are dense and non-dense breast. Second, we trained the residual neural network to classify mammograms according to the four classes of the BI-RADS standard. We evaluated the performance in terms of the accuracy and we obtained very good results compared to other works on similar classification tasks. In the near future, we are going to improve the results by increasing the computing power, by improving the quality of the ground truth and by increasing the number of samples in the dataset.

[1]  Jian Sun,et al.  Deep Residual Learning for Image Recognition , 2015, 2016 IEEE Conference on Computer Vision and Pattern Recognition (CVPR).

[2]  Davide Caramella,et al.  Evaluation of Dosimetric Properties in Full Field Digital Mammography (FFDM) - Development of a New Dose Index , 2018, BIODEVICES.

[3]  G. Giles,et al.  Longitudinal Study of Mammographic Density Measures That Predict Breast Cancer Risk , 2017, Cancer Epidemiology, Biomarkers & Prevention.

[4]  V. McCormack,et al.  Breast Density and Parenchymal Patterns as Markers of Breast Cancer Risk: A Meta-analysis , 2006, Cancer Epidemiology Biomarkers & Prevention.

[5]  S. Ciatto,et al.  Categorizing breast mammographic density: intra- and interobserver reproducibility of BI-RADS density categories. , 2005, Breast.

[6]  Jacques Wainer,et al.  Breast Density Classification with Convolutional Neural Networks , 2016, CIARP.

[7]  Average absorbed breast dose in mammography: a new possible dose index matching the requirements of the European Directive 2013/59/EURATOM , 2017, European Radiology Experimental.

[8]  Samuel J. Magny,et al.  Breast Imaging Reporting and Data System , 2020, Definitions.

[9]  Sergey Ioffe,et al.  Batch Normalization: Accelerating Deep Network Training by Reducing Internal Covariate Shift , 2015, ICML.

[10]  Nan Wu,et al.  Breast Density Classification with Deep Convolutional Neural Networks , 2017, 2018 IEEE International Conference on Acoustics, Speech and Signal Processing (ICASSP).

[11]  M. McEntee,et al.  Assessment of Interradiologist Agreement Regarding Mammographic Breast Density Classification Using the Fifth Edition of the BI-RADS Atlas. , 2016, AJR. American journal of roentgenology.

[12]  Michael Bretthauer,et al.  Benefits and harms of mammography screening , 2015, Breast Cancer Research.

[13]  Karla Kerlikowske,et al.  Radiation-Induced Breast Cancer Incidence and Mortality From Digital Mammography Screening , 2016, Annals of Internal Medicine.

[14]  Olivier Alonzo-Proulx,et al.  Reliability of automated breast density measurements. , 2015, Radiology.