Circulating tumour‐associated plasma DNA represents an independent and informative predictor of prostate cancer

To investigate whether preoperative plasma levels of free DNA can discriminate between men with localized prostate cancer and benign prostatic hyperplasia (BPH).

[1]  A. Harris,et al.  Prospective Study of Quantitation of Plasma DNA Levels in the Diagnosis of Malignant versus Benign Prostate Disease , 2005, Clinical Cancer Research.

[2]  Rosalie Nolley,et al.  The prostate specific antigen era in the United States is over for prostate cancer: what happened in the last 20 years? , 2004, The Journal of urology.

[3]  K. Pantel,et al.  Detection and Characterization of Circulating Microsatellite‐DNA in Blood of Patients with Breast Cancer , 2004, Annals of the New York Academy of Sciences.

[4]  S. O’Day,et al.  Quantification of Circulating DNA in the Plasma and Serum of Cancer Patients , 2004, Annals of the New York Academy of Sciences.

[5]  S. Loening,et al.  Increased cell-free DNA in plasma of patients with metastatic spread in prostate cancer. , 2004, Cancer letters.

[6]  U. Pastorino,et al.  Quantification of free circulating DNA as a diagnostic marker in lung cancer. , 2003, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[7]  Michael W Kattan,et al.  Judging new markers by their ability to improve predictive accuracy. , 2003, Journal of the National Cancer Institute.

[8]  H. Mulcahy,et al.  Circulating nucleic acids in plasma and serum as a noninvasive investigation for cancer: Time for large‐scale clinical studies? , 2003, International journal of cancer.

[9]  James T. Wu,et al.  Cell-free DNA: measurement in various carcinomas and establishment of normal reference range. , 2002, Clinica chimica acta; international journal of clinical chemistry.

[10]  M. Provencio,et al.  Detection of epithelial tumour RNA in the plasma of colon cancer patients is associated with advanced stages and circulating tumour cells , 2002, Gut.

[11]  D. Jb,et al.  Difference between free circulating plasma and serum DNA in patients with colorectal liver metastases. , 2002 .

[12]  D. Swinkels,et al.  Difference between free circulating plasma and serum DNA in patients with colorectal liver metastases. , 2002, Anticancer research.

[13]  F. O. Fackelmayer,et al.  DNA fragments in the blood plasma of cancer patients: quantitations and evidence for their origin from apoptotic and necrotic cells. , 2001, Cancer research.

[14]  K. Miller,et al.  Fluorescent methylation-specific polymerase chain reaction for DNA-based detection of prostate cancer in bodily fluids. , 2000, Cancer research.

[15]  David Sidransky,et al.  Microsatellite alterations in serum DNA of head and neck cancer patients , 1996, Nature Medicine.

[16]  M. Stroun,et al.  Neoplastic characteristics of the DNA found in the plasma of cancer patients. , 1989, Oncology.

[17]  B. Shapiro,et al.  Determination of circulating DNA levels in patients with benign or malignant gastrointestinal disease , 1983, Cancer.

[18]  C. Steinman.  Circulating DNA in polyarteritis nodosa and related syndromes. , 1982, Arthritis and rheumatism.

[19]  G. Ehrlich,et al.  Free DNA in the serum of rheumatoid arthritis patients. , 1977, The Journal of rheumatology.

[20]  P Mandel,et al.  Les acides nucleiques du plasma sanguin chez l' homme , 1948 .