The XLMR gene ACSL4 plays a role in dendritic spine architecture

[1]  D. Linseman,et al.  Diverse roles of Rho family GTPases in neuronal development, survival, and death. , 2008, Frontiers in bioscience : a journal and virtual library.

[2]  K. Huse,et al.  Functional characterization of two novel 5' untranslated exons reveals a complex regulation of NOD2 protein expression , 2007, BMC Genomics.

[3]  G. Ramakers,et al.  Loss of X-Linked Mental Retardation Gene Oligophrenin1 in Mice Impairs Spatial Memory and Leads to Ventricular Enlargement and Dendritic Spine Immaturity , 2007, The Journal of Neuroscience.

[4]  T. Shirao,et al.  Role of actin cytoskeleton in dendritic spine morphogenesis , 2007, Neurochemistry International.

[5]  S. Kaech,et al.  Culturing hippocampal neurons , 2006, Nature Protocols.

[6]  D. Muller,et al.  Sequential implication of the mental retardation proteins ARHGEF6 and PAK3 in spine morphogenesis , 2006, Journal of Cell Science.

[7]  W. Greenough,et al.  Hippocampal pyramidal cells in adult Fmr1 knockout mice exhibit an immature-appearing profile of dendritic spines , 2006, Brain Research.

[8]  Jinsong Meng,et al.  Abnormal Long-Lasting Synaptic Plasticity and Cognition in Mice Lacking the Mental Retardation Gene Pak3 , 2005, The Journal of Neuroscience.

[9]  W. Greenough,et al.  Dendritic spine abnormalities in the occipital cortex of C57BL/6 Fmr1 knockout mice , 2005, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

[10]  A. Renieri,et al.  Non‐syndromic X‐linked mental retardation: From a molecular to a clinical point of view , 2005, Journal of cellular physiology.

[11]  L. Van Aelst,et al.  Rho GTPases, dendritic structure, and mental retardation. , 2005, Journal of neurobiology.

[12]  Mary B. Kennedy,et al.  Spine architecture and synaptic plasticity , 2005, Trends in Neurosciences.

[13]  Elena B. Pasquale,et al.  Molecular mechanisms of dendritic spine development and remodeling , 2005, Progress in Neurobiology.

[14]  J. Kapur,et al.  Synaptic and extrasynaptic localization of brain‐derived neurotrophic factor and the tyrosine kinase B receptor in cultured hippocampal neurons , 2004, The Journal of comparative neurology.

[15]  C. Vicario-Abejón Long‐Term Culture of Hippocampal Neurons , 2004, Current protocols in neuroscience.

[16]  S. Siegelbaum,et al.  12-Lipoxygenase Metabolites of Arachidonic Acid Mediate Metabotropic Glutamate Receptor-Dependent Long-Term Depression at Hippocampal CA3-CA1 Synapses , 2003, The Journal of Neuroscience.

[17]  T. Yaguchi,et al.  Arachidonic acid peroxides induce apoptotic Neuro-2A cell death in association with intracellular Ca2+ rise and mitochondrial damage independently of caspase-3 activation , 2003, Brain Research.

[18]  B. Jacobson,et al.  Cyclooxygenase and cAMP-dependent protein kinase reorganize the actin cytoskeleton for motility in HeLa cells. , 2003, Cell motility and the cytoskeleton.

[19]  M. Chechlacz,et al.  Is mental retardation a defect of synapse structure and function? , 2003, Pediatric neurology.

[20]  R. D'Hooge,et al.  CALL interrupted in a patient with non-specific mental retardation: gene dosage-dependent alteration of murine brain development and behavior. , 2003, Human molecular genetics.

[21]  P. Newsholme,et al.  Polyunsaturated and monounsaturated fatty acids increase neutral lipid accumulation, caspase activation and apoptosis in a neutrophil-like, differentiated HL-60 cell line. , 2003, Clinical science.

[22]  P. Marynen,et al.  A third MRX family (MRX68) is the result of mutation in the long chain fatty acid-CoA ligase 4 (FACL4) gene: proposal of a rapid enzymatic assay for screening mentally retarded patients , 2003, Journal of medical genetics.

[23]  B. Jacobson,et al.  Arachidonic acid signaling to the cytoskeleton: the role of cyclooxygenase and cyclic AMP-dependent protein kinase in actin bundling. , 2002, Cell motility and the cytoskeleton.

[24]  M. Berridge,et al.  The endoplasmic reticulum: a multifunctional signaling organelle. , 2002, Cell calcium.

[25]  P. Chapman,et al.  Deletion of the mental retardation gene Gdi1 impairs associative memory and alters social behavior in mice. , 2002, Human molecular genetics.

[26]  M. Lynch,et al.  Long-term potentiation in aged rats is restored when the age-related decrease in polyunsaturated fatty acid concentration is reversed. , 2002, Prostaglandins, leukotrienes, and essential fatty acids.

[27]  F. Vitelli,et al.  Alport syndrome and mental retardation: clinical and genetic dissection of the contiguous gene deletion syndrome in Xq22.3 (ATS-MR) , 2002, Journal of medical genetics.

[28]  H. Ropers,et al.  FACL4, encoding fatty acid-CoA ligase 4, is mutated in nonspecific X-linked mental retardation , 2002, Nature Genetics.

[29]  Ger J. A. Ramakers,et al.  Rho proteins, mental retardation and the cellular basis of cognition , 2002, Trends in Neurosciences.

[30]  B. Dickson Rho GTPases in growth cone guidance , 2001, Current Opinion in Neurobiology.

[31]  A. Matus,et al.  Actin-based plasticity in dendritic spines. , 2000, Science.

[32]  G. Zimmerman,et al.  Intracellular unesterified arachidonic acid signals apoptosis. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[33]  Y. Izumi,et al.  Arachidonic acid rescues hippocampal long-term potentiation blocked by group I metabotropic glutamate receptor antagonists , 2000, Neuroscience.

[34]  G. Zimmerman,et al.  Expression of fatty acid‐CoA ligase 4 during development and in brain , 2000, FEBS letters.

[35]  S. Spanò,et al.  CtBP/BARS induces fission of Golgi membranes by acylating lysophosphatidic acid , 1999, Nature.

[36]  A. Podtelejnikov,et al.  Endophilin I mediates synaptic vesicle formation by transfer of arachidonate to lysophosphatidic acid , 1999, Nature.

[37]  E. Traer,et al.  Cloning, expression, and chromosomal localization of human long-chain fatty acid-CoA ligase 4 (FACL4). , 1998, Genomics.

[38]  G. Borsani,et al.  FACL4, a new gene encoding long-chain acyl-CoA synthetase 4, is deleted in a family with Alport syndrome, elliptocytosis, and mental retardation. , 1998, Genomics.

[39]  A. Hall,et al.  Rho GTPases and the actin cytoskeleton. , 1998, Science.

[40]  H. Sasano,et al.  A novel arachidonate-preferring acyl-CoA synthetase is present in steroidogenic cells of the rat adrenal, ovary, and testis. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[41]  G. Turner Finding genes on the X chromosome by which homo may have become sapiens. , 1996, American journal of human genetics.

[42]  Jang-Soo Chun,et al.  Differential Translocation of Protein Kinase C ε during HeLa Cell Adhesion to a Gelatin Substratum* , 1996, The Journal of Biological Chemistry.

[43]  N. Smalheiser,et al.  Rapid regulation of neurite outgrowth and retraction by phospholipase A2-derived arachidonic acid and its metabolites , 1996, Brain Research.

[44]  G. Warren,et al.  Characterization of a cis-Golgi matrix protein, GM130 , 1995, The Journal of cell biology.

[45]  D. Linden Phospholipase A2 controls the induction of short-term versus long-term depression in the cerebellar Purkinje neuron in culture , 1995, Neuron.

[46]  S. Siegelbaum,et al.  Hippocampal long-term depression: Arachidonic acid as a potential retrograde messenger , 1995, Neuropharmacology.

[47]  P. L. Campbell,et al.  EEA1, an Early Endosome-Associated Protein. , 1995, The Journal of Biological Chemistry.

[48]  M. Vallano,et al.  Arachidonic Acid, but Not Sodium Nitroprusside, Stimulates Presynaptic Protein Kinase C and Phosphorylation of GAP‐43 in Rat Hippocampal Slices and Synaptosomes , 1995, Journal of neurochemistry.

[49]  H. Saito,et al.  Arachidonic acid: Toxic and trophic effects on cultured hippocampal neurons , 1994, Neuroscience.

[50]  F. Walsh,et al.  Characterisation of the second messenger pathway underlying neurite outgrowth stimulated by FGF. , 1994, Development.

[51]  F. Walsh,et al.  The Production of Arachidonic Acid Can Account for Calcium Channel Activation in the Second Messenger Pathway Underlying Neurite Outgrowth Stimulated by NCAM, N‐Cadherin, and L1 , 1994, Journal of neurochemistry.

[52]  D. Piomelli Eicosanoids in synaptic transmission. , 1994, Critical reviews in neurobiology.

[53]  W. Maxwell Cowan,et al.  Rat hippocampal neurons in dispersed cell culture , 1977, Brain Research.

[54]  D. Purpura,et al.  Dendritic Spine "Dysgenesis" and Mental Retardation , 1974, Science.