Circadian rhythms and bright light: Recommendations for shift work

Abstract This paper starts with a brief review of the basic principles of human circadian rhythms relevant to understanding the problem of shift work. It then presents a more detailed critical review of the recent bright light literature, with an emphasis on methodological shortcomings, alternative interpretations, and areas that need further research. Evidence is presented which suggests that either a light-dark cycle (which includes bright light) or a sleep-wake schedule can act as a zeitgeber for human circadian rhythms. Current human phase response curves to bright light are reviewed. Light-work-sleep schedules are presented which have been designed to eliminate the physiologically based harmful consequences of shift work. These schedules include both bright light and sleep-wake schedule zeitgebers. Other practical applications of bright light treatment are mentioned.

[1]  Patricia J. De Coursey,et al.  Daily light sensitivity rhythm in a rodent. , 1960 .

[2]  R. Wever,et al.  Re-entrainment of circadian rhythms after phase-shifts of the Zeitgeber. , 1975, Chronobiologia.

[3]  Jürgen Aschoff,et al.  The Circadian System of Man , 1979 .

[4]  D A Newsome,et al.  Light suppresses melatonin secretion in humans. , 1980, Science.

[5]  C A Czeisler,et al.  Human sleep: its duration and organization depend on its circadian phase. , 1980, Science.

[6]  C. Pittendrigh Circadian Systems: Entrainment , 1981 .

[7]  David Minors,et al.  Circadian Rhythms and the Human , 1981 .

[8]  C A Czeisler,et al.  ENTRAINMENT OF HUMAN ORCADIAN RHYTHMS BY LIGHT‐DARK CYCLES: A REASSESSMENT , 1981, Photochemistry and photobiology.

[9]  T. Åkerstedt,et al.  The circadian variation of experimentally displaced sleep. , 1981, Sleep.

[10]  J. Aschoff Freerunning and Entrained Circadian Rhythms , 1981 .

[11]  T. Åkerstedt,et al.  Displacement of the sleep period and sleep deprivation. Implications for shift work. , 1982, Human neurobiology.

[12]  C A Czeisler,et al.  Mathematical model of the human circadian system with two interacting oscillators. , 1982, The American journal of physiology.

[13]  M. Carskadon,et al.  Circadian variation of sleep tendency in elderly and young adult subjects. , 1982, Sleep.

[14]  W P Colquhoun,et al.  The Twenty-four Hour Workday: Proceedings of a Symposium on Variations in Work-Sleep Schedules , 1983 .

[15]  S. Daan,et al.  Timing of human sleep: recovery process gated by a circadian pacemaker. , 1984, The American journal of physiology.

[16]  S. Daan,et al.  Scheduled exposure to daylight: a potential strategy to reduce "jet lag" following transmeridian flight. , 1984, Psychopharmacology bulletin.

[17]  Lewy Aj,et al.  Assessment and treatment of chronobiologic disorders using plasma melatonin levels and bright light exposure: the clock-gate model and the phase response curve. , 1984 .

[18]  C. M. Singer,et al.  Immediate and Delayed Effects of Bright Light on Human Melatonin Production: Shifting “Dawn” and “Dusk” Shifts the Dim Light Melatonin Onset (DLMO) a , 1985, Annals of the New York Academy of Sciences.

[19]  L. Thorington,et al.  Spectral, Irradiance, and Temporal Aspects of Natural and Artificial Light , 1985, Annals of the New York Academy of Sciences.

[20]  T. Monk,et al.  Hours of work : temporal factors in work scheduling , 1985 .

[21]  S. Campbell,et al.  Napping behavior during "spontaneous internal desynchronization": sleep remains in synchrony with body temperature. , 1985, Human neurobiology.

[22]  S Folkard,et al.  Chronobiology and shift work: current issues and trends. , 1990, Chronobiologia.

[23]  R. Wever,et al.  Use of Light to Treat Jet Lag: Differential Effects of Normal and Bright Artificial Light on Human Circadian Rhythms , 1985, Annals of the New York Academy of Sciences.

[24]  S. Strogatz,et al.  Bright light resets the human circadian pacemaker independent of the timing of the sleep-wake cycle. , 1986, Science.

[25]  Wever Ra Characteristics of circadian rhythms in human functions. , 1986 .

[26]  Daniel F. Kripke,et al.  Natural light exposure of young adults , 1986, Physiology & Behavior.

[27]  Timothy H. Monk Advantages and Disadvantages of Rapidly Rotating Shift Schedules—A Circadian Viewpoint , 1986 .

[28]  J. Aschoff,et al.  Circadian Activity Rhythms in Squirrel Monkeys: Entrainment by Temperature Cycles 1 , 1986, Journal of biological rhythms.

[29]  S. Folkard,et al.  Bright light phase shifts the human melatonin rhythm during the Antarctic winter , 1987, Neuroscience Letters.

[30]  T. Brenn,et al.  Midwinter insomnia in the subarctic region: Evening levels of serum melatonin and cortisol before and after treatment with bright artificial light , 1987, Acta psychiatrica Scandinavica.

[31]  N. Mrosovsky,et al.  A behavioural method for accelerating re-entrainment of rhythms to new light—dark cycles , 1987, Nature.

[32]  C. Eastman The circadian rhythm of temperature in humans during a 26-hr sleep-wake schedule , 1987, Physiology & Behavior.

[33]  S. Daan,et al.  Reduction of human sleep duration after bright light exposure in the morning , 1987, Neuroscience Letters.

[34]  A. Lewy,et al.  Antidepressant and circadian phase-shifting effects of light. , 1987, Science.

[35]  A. Lewy,et al.  Free-Running Melatonin Rhythms in Blind People: Phase Shifts with Melatonin and Triazolam Administration , 1987 .

[36]  C. Eastman Bright Light in Work-Sleep Schedules for Shift Workers: Application of Circadian Rhythm Principles , 1987 .

[37]  Scott S. Campbell,et al.  Exposure to light in healthy elderly subjects and alzheimer's patients , 1988, Physiology & Behavior.

[38]  D. Dinges,et al.  Catastrophes, sleep, and public policy: consensus report. , 1988, Sleep.

[39]  Clifford M. Singer,et al.  Winter Depression and the Phase-Shift Hypothesis for Bright Light's Therapeutic Effects: History, Theory, and Experimental Evidence , 1988, Journal of biological rhythms.

[40]  T. Wehr,et al.  Phototherapy for Seasonal Affective Disorder , 1988, Journal of biological rhythms.

[41]  T. Åkerstedt,et al.  Sleepiness as a consequence of shift work. , 1988, Sleep.

[42]  R. Wever,et al.  Light Effects on Human Circadian Rhythms: A Review of Recent Andechs Experiments , 1989, Journal of biological rhythms.

[43]  R. Kronauer,et al.  Bright light induction of strong (type 0) resetting of the human circadian pacemaker. , 1989, Science.

[44]  S. Daan,et al.  Bright morning light advances the human circadian system without affecting NREM sleep homeostasis. , 1989, The American journal of physiology.

[45]  D. Kripke,et al.  Morning versus evening bright light treatment of late luteal phase dysphoric disorder. , 1989, The American journal of psychiatry.

[46]  R. Allen,et al.  Phase-shifting effects of bright morning light as treatment for delayed sleep phase syndrome. , 1990, Sleep.