High-fat diet-induced functional and pathological changes in lacrimal gland.

[1]  K. Tsai,et al.  High Fat Diet Suppresses Peroxisome Proliferator-Activated Receptors and Reduces Dopaminergic Neurons in the Substantia Nigra , 2019, International journal of molecular sciences.

[2]  Z. Peng,et al.  Reactive Oxygen Species-Induced Lipid Peroxidation in Apoptosis, Autophagy, and Ferroptosis , 2019, Oxidative medicine and cellular longevity.

[3]  Luís Rato,et al.  A switch from high-fat to normal diet does not restore sperm quality but prevents metabolic syndrome. , 2019, Reproduction.

[4]  A. Quantock,et al.  Hyperlipidemia induces meibomian gland dysfunction. , 2019, The ocular surface.

[5]  Liying Tang,et al.  Sleep Deprivation Induces Dry Eye Through Inhibition of PPARα Expression in Corneal Epithelium. , 2018, Investigative ophthalmology & visual science.

[6]  M. Kolehmainen,et al.  High‐Fat Diet, Betaine, and Polydextrose Induce Changes in Adipose Tissue Inflammation and Metabolism in C57BL/6J Mice , 2018, Molecular nutrition & food research.

[7]  Hong-Bin Fang,et al.  Prevention of Lipid Peroxidation–derived Cyclic DNA Adduct and Mutation in High-Fat Diet–induced Hepatocarcinogenesis by Theaphenon E , 2018, Cancer Prevention Research.

[8]  Tsui-Chin Huang,et al.  Protective Effect of Melatonin against Oxidative Stress-Induced Apoptosis and Enhanced Autophagy in Human Retinal Pigment Epithelium Cells , 2018, Oxidative medicine and cellular longevity.

[9]  M. M. Sarandy,et al.  High-Fat Diet and Alcohol Intake Promotes Inflammation and Impairs Skin Wound Healing in Wistar Rats , 2018, Mediators of inflammation.

[10]  F. Paulsen,et al.  Myoepithelial cell-driven acini contraction in response to oxytocin receptor stimulation is impaired in lacrimal glands of Sjögren’s syndrome animal models , 2018, Scientific Reports.

[11]  P. Gama,et al.  High‐fat diet affects gut nutrients transporters in hypo and hyperthyroid mice by PPAR‐a independent mechanism , 2018, Life sciences.

[12]  Yu Zhu,et al.  Sleep deprivation disrupts the lacrimal system and induces dry eye disease , 2018, Experimental & Molecular Medicine.

[13]  G. Derosa,et al.  The role of various peroxisome proliferator‐activated receptors and their ligands in clinical practice , 2018, Journal of cellular physiology.

[14]  K. Tsubota,et al.  A Ligation of the Lacrimal Excretory Duct in Mouse Induces Lacrimal Gland Inflammation with Proliferative Cells , 2017, Stem cells international.

[15]  Pingping Shen,et al.  Apigenin, a modulator of PPAR&ggr;, attenuates HFD‐induced NAFLD by regulating hepatocyte lipid metabolism and oxidative stress via Nrf2 activation , 2017, Biochemical pharmacology.

[16]  Stefano Bonini,et al.  TFOS DEWS II pathophysiology report. , 2017, The ocular surface.

[17]  P. Asbell,et al.  TFOS DEWS II Clinical Trial Design Report. , 2017, The ocular surface.

[18]  Zuguo Liu,et al.  Dry Eye Management: Targeting the Ocular Surface Microenvironment , 2017, International journal of molecular sciences.

[19]  S. Kersten,et al.  The role and regulation of the peroxisome proliferator activated receptor alpha in human liver. , 2017, Biochimie.

[20]  Y. Isaka,et al.  High-Fat Diet-Induced Lysosomal Dysfunction and Impaired Autophagic Flux Contribute to Lipotoxicity in the Kidney. , 2017, Journal of the American Society of Nephrology : JASN.

[21]  E. Levy,et al.  Oxidative Stress as a Critical Factor in Nonalcoholic Fatty Liver Disease Pathogenesis. , 2017, Antioxidants & redox signaling.

[22]  G. Carpenter,et al.  Altered autophagy and sympathetic innervation in salivary glands from high-fat diet mice. , 2017, Archives of oral biology.

[23]  Huawei Zeng,et al.  High Fat Diet Alters Gut Microbiota and the Expression of Paneth Cell-Antimicrobial Peptides Preceding Changes of Circulating Inflammatory Cytokines , 2017, Mediators of inflammation.

[24]  Shuo Wang,et al.  Oxidative Stress Mediated Hippocampal Neuron Apoptosis Participated in Carbon Disulfide-Induced Rats Cognitive Dysfunction , 2016, Neurochemical Research.

[25]  Shauna L. Parkes,et al.  Switching Adolescent High-Fat Diet to Adult Control Diet Restores Neurocognitive Alterations , 2016, Frontiers in behavioral neuroscience.

[26]  Yulong Yin,et al.  Oxidative Stress and Inflammation: What Polyphenols Can Do for Us? , 2016, Oxidative medicine and cellular longevity.

[27]  Patrice D Cani,et al.  High-fat diet feeding differentially affects the development of inflammation in the central nervous system , 2016, Journal of Neuroinflammation.

[28]  J. Kloehn,et al.  Reversing diet-induced metabolic dysregulation by diet switching leads to altered hepatic de novo lipogenesis and glycerolipid synthesis , 2016, Scientific Reports.

[29]  K. Tsubota,et al.  Tissue Renin–Angiotensin System in Lacrimal Gland Fibrosis in a Murine Model of Chronic Graft-Versus-Host Disease , 2015, Cornea.

[30]  C. Kublin,et al.  Role of Matrix Metalloproteinases 2 and 9 in Lacrimal Gland Disease in Animal Models of Sjögren's Syndrome. , 2015, Investigative ophthalmology & visual science.

[31]  H. Makarenkova,et al.  Myoepithelial Cells: Their Origin and Function in Lacrimal Gland Morphogenesis, Homeostasis, and Repair , 2015, Current Molecular Biology Reports.

[32]  P. Langer,et al.  Bilateral lacrimal gland disease: clinical features of 97 cases. , 2014, Ophthalmology.

[33]  Antonio Ayala,et al.  Lipid Peroxidation: Production, Metabolism, and Signaling Mechanisms of Malondialdehyde and 4-Hydroxy-2-Nonenal , 2014, Oxidative medicine and cellular longevity.

[34]  Orsu Prabhakar,et al.  Cerebroprotective effect of resveratrol through antioxidant and anti-inflammatory effects in diabetic rats , 2013, Naunyn-Schmiedeberg's Archives of Pharmacology.

[35]  Herng‐Ching Lin,et al.  Comorbidities of dry eye disease: a nationwide population‐based study , 2012, Acta ophthalmologica.

[36]  K. Tsubota,et al.  Age-related dysfunction of the lacrimal gland and oxidative stress: evidence from the Cu,Zn-superoxide dismutase-1 (Sod1) knockout mice. , 2012, The American journal of pathology.

[37]  L. Rossoni,et al.  Oxidative stress and inflammatory mediators contribute to endothelial dysfunction in high-fat diet-induced obesity in mice , 2010, Journal of hypertension.

[38]  Roderick T. Hori,et al.  Peroxisome proliferator activated receptor α (PPARα) and PPAR gamma coactivator (PGC-1α) induce carnitine palmitoyltransferase IA (CPT-1A) via independent gene elements , 2010, Molecular and Cellular Endocrinology.

[39]  Jiang F Zhong,et al.  Altered expression of genes functioning in lipid homeostasis is associated with lipid deposition in NOD mouse lacrimal gland. , 2009, Experimental eye research.

[40]  Darlene,et al.  The aging lacrimal gland: changes in structure and function. , 2008, The ocular surface.

[41]  M. Genestra.  Oxyl radicals, redox-sensitive signalling cascades and antioxidants. , 2007, Cellular signalling.

[42]  C. Kublin,et al.  A single injection of interleukin-1 induces reversible aqueous-tear deficiency, lacrimal gland inflammation, and acinar and ductal cell proliferation. , 2007, Experimental eye research.

[43]  C. Ding,et al.  Unique Ultrastructure of Exorbital Lacrimal Glands in Male NOD and BALB/c Mice , 2006, Current eye research.

[44]  Neil Mann,et al.  Origins and evolution of the Western diet: health implications for the 21st century. , 2005, The American journal of clinical nutrition.

[45]  Friedrich Paulsen,et al.  Human lacrimal gland mucins , 2004, Cell and Tissue Research.

[46]  P. Brandt,et al.  Peroxisome proliferator-activated receptor agonists inhibit interleukin-1beta-mediated nitric oxide production in cultured lacrimal gland acinar cells. , 2003, Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics.

[47]  J. Schaffer,et al.  Lipotoxicity: when tissues overeat , 2003, Current opinion in lipidology.

[48]  S. Crispin.  Ocular lipid deposition and hyperlipoproteinaemia , 2002, Progress in Retinal and Eye Research.

[49]  Thomas D. Schmittgen,et al.  Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. , 2001, Methods.

[50]  R. Klein,et al.  Prevalence of and risk factors for dry eye syndrome. , 2000, Archives of ophthalmology.

[51]  J. Parks,et al.  Mitochondrial abnormalities in non-alcoholic steatohepatitis. , 1999, Journal of hepatology.

[52]  V. Laudet,et al.  Fibrates increase human REV-ERBalpha expression in liver via a novel peroxisome proliferator-activated receptor response element. , 1999, Molecular endocrinology.

[53]  B. Walcott.  The Lacrimal Gland and Its Veil of Tears. , 1998, News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society.

[54]  C. Bode,et al.  A diet rich in fat and poor in dietary fiber increases the in vitro formation of reactive oxygen species in human feces. , 1997, The Journal of nutrition.

[55]  J. McGarry,et al.  The mitochondrial carnitine palmitoyltransferase system. From concept to molecular analysis. , 1997, European journal of biochemistry.

[56]  Y. Satoh,et al.  Morphological changes of myoepithelial cells of mouse lacrimal glands during postnatal development. , 1995, Histology and histopathology.

[57]  J. Gustafsson,et al.  Fatty acids activate a chimera of the clofibric acid-activated receptor and the glucocorticoid receptor. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[58]  B. Damato,et al.  Senile atrophy of the human lacrimal gland: the contribution of chronic inflammatory disease. , 1984, The British journal of ophthalmology.

[59]  J. Goldman,et al.  Pseudo-Sjögren syndrome with hyperlipoproteinemia. , 1977, JAMA.

[60]  P. Silveyra,et al.  Oxidative stress and cellular pathways of asthma and inflammation: Therapeutic strategies and pharmacological targets , 2018, Pharmacology & therapeutics.

[61]  R. Jonsson,et al.  Sjögren syndrome , 2016, Nature Reviews Disease Primers.

[62]  M. Lemullois,et al.  Immunolocalization of myoepithelial cells in isolated acini of rat exorbital lacrimal gland: Cellular distribution of muscarinic receptors , 1996, Biology of the cell.

[63]  H. Esterbauer,et al.  Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes. , 1991, Free radical biology & medicine.

[64]  W. Pryor.  On the detection of lipid hydroperoxides in biological samples. , 1989, Free radical biology & medicine.

[65]  A. Aljada,et al.  The Journal of Clinical Endocrinology & Metabolism Printed in U.S.A. Copyright © 2001 by The Endocrine Society The Suppressive Effect of Dietary Restriction and Weight Loss in the Obese on the Generation of Reactive Oxygen Species by Leukocytes, Lipid Per , 2022 .