Robot-assisted light dose evaluation for endoscopically guided photodynamic therapy: A preliminary study

Conventional endoscope-guided photodynamic therapy (PDT) suffers mostly from motion artifacts, therefore expert hand-eye coordination was always needed during manual operations. In this paper we introduced a visual servo scheme to handle the tracking problem between the focused area and the targeted lesions. The scheme is consisted of real-time feature matching, relative motion cancellation and real-time light dose surveillance. Experiments were carried out both on simulated data and a silicon phantom. It indicats that this scheme outperforms the conventional scheme in terms of reduction in operation time and exposure to healthy tissue.

[1]  Wyatt S. Newman,et al.  Experimental evaluation of a robotic image-directed radiation therapy system , 2000, Proceedings 2000 ICRA. Millennium Conference. IEEE International Conference on Robotics and Automation. Symposia Proceedings (Cat. No.00CH37065).

[2]  S. Somers,et al.  Radiological appearance of migrating motor complex of the small intestine , 1988, Gastrointestinal Radiology.

[3]  M. Feuerstein,et al.  Navigation in endoscopic soft tissue surgery: perspectives and limitations. , 2008, Journal of endourology.

[4]  Guang-Zhong Yang,et al.  A Probabilistic Framework for Tracking Deformable Soft Tissue in Minimally Invasive Surgery , 2007, MICCAI.

[5]  Ozkan Bebek,et al.  Intelligent control algorithms for robotic-assisted beating heart surgery , 2007, IEEE Transactions on Robotics.

[6]  T. Dougherty An update on photodynamic therapy applications. , 2002, Journal of clinical laser medicine & surgery.

[7]  J. Adler,et al.  Robotic Motion Compensation for Respiratory Movement during Radiosurgery , 2000, Computer aided surgery : official journal of the International Society for Computer Aided Surgery.