Dermatoglyphics in Leukemia

Extract: The study of dermatoglyphic features of 76 Caucasian patients with acute lymphocytic leukemia revealed that male patients had higher frequency of digital whorls (33%) than their brothers (26.7%) or fathers (27.8%). Patients with leukemia and their sibs had more Sydney palmar flexion creases (41.3% and 35.4%) than their parents (10.9%) or two control groups (20.4% and 10.5%).Speculation: The association of acute lymphocytic leukemia to increased frequency of digital whorl patterns and Sydney palmar flexion creases can now be tested prospectively. Confirmation of an association between leukemia and these dermatoglyphic features would indicate a relationship between prenatal characteristics and leukemogenesis.