The role of anticytokine therapy in heart failure: recent lessons from preclinical and clinical trials?
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[1] L. Old,et al. Tumor necrosis factor (TNF). , 1985, Science.
[2] K. Sliwa,et al. Beneficial Effects of Pentoxifylline in Patients With Idiopathic Dilated Cardiomyopathy Treated With Angiotensin-Converting Enzyme Inhibitors and Carvedilol: Results of a Randomized Study , 2001, Circulation.
[3] D. Wagner,et al. AMPD1 gene mutation in congestive heart failure: new insights into the pathobiology of disease progression. , 1999, Circulation.
[4] W. Colucci,et al. Interleukin-1β and Tumor Necrosis Factor-α Decrease Collagen Synthesis and Increase Matrix Metalloproteinase Activity in Cardiac Fibroblasts In Vitro , 2000 .
[5] Simon C Watkins,et al. Negative inotropic effects of cytokines on the heart mediated by nitric oxide. , 1992, Science.
[6] F. Breedveld,et al. Functional Analysis of a Human Tumor Necrosis Factor α (TNF-α) Promoter Polymorphism Related to Joint Damage in Rheumatoid Arthritis , 1998, Molecular medicine.
[7] L. Moldawer,et al. Direct Evidence for Cytokine Involvement in Neointimal Hyperplasia , 2000, Circulation.
[8] E. Vizi,et al. Isoproterenol regulates tumour necrosis factor, interleukin‐10, interleukin‐6 and nitric oxide production and protects against the development of vascular hyporeactivity in endotoxaemia , 1997, Immunology.
[9] F. Parhami,et al. Tumor Necrosis Factor-&agr; Promotes In Vitro Calcification of Vascular Cells via the cAMP Pathway , 2000, Circulation.
[10] G. Freeman,et al. beta-adrenergic blockade in developing heart failure: effects on myocardial inflammatory cytokines, nitric oxide, and remodeling. , 2000, Circulation.
[11] C. Perez,et al. A novel form of TNF/cachectin is a cell surface cytotoxic transmembrane protein: Ramifications for the complex physiology of TNF , 1988, Cell.
[12] M. Seishima,et al. Tumor Necrosis Factor-α (TNF-α) Plays a Protective Role in Acute Viral Myocarditis in Mice , 2001 .
[13] B. Beutler,et al. A reporter transgene indicates renal-specific induction of tumor necrosis factor (TNF) by shiga-like toxin. Possible involvement of TNF in hemolytic uremic syndrome. , 1993, The Journal of clinical investigation.
[14] P. Zabel,et al. OXPENTIFYLLINE IN ENDOTOXAEMIA , 1989, The Lancet.
[15] K. Tracey,et al. Peptide Regulatory Factors CACHECTIN/TUMOUR NECROSIS FACTOR , 1989, The Lancet.
[16] Anita Deswal,et al. Cytokines and Cytokine Receptors in Advanced Heart Failure: An Analysis of the Cytokine Database from the Vesnarinone Trial (VEST) , 2001, Circulation.
[17] K. Sliwa,et al. Randomised investigation of effects of pentoxifylline on left-ventricular performance in idiopathic dilated cardiomyopathy , 1998, The Lancet.
[18] A. Blakemore,et al. Single base polymorphism in the human tumour necrosis factor alpha (TNF alpha) gene detectable by NcoI restriction of PCR product. , 1992, Human molecular genetics.
[19] B. Beutler,et al. Prolonged and effective blockade of tumor necrosis factor activity through adenovirus-mediated gene transfer. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[20] G. Duff,et al. Genetics of tumour necrosis factor-alpha in autoimmune, infectious, and neoplastic diseases. , 1995, Journal of inflammation.
[21] D. Mann,et al. Effects of Tumor Necrosis Factor Gene Polymorphisms on Patients With Congestive Heart Failure , 1998 .
[22] E. Thonar,et al. Levels of circulating tumor necrosis factor alpha and interleukin-6 in patients with rheumatoid arthritis. Relationship to serum levels of hyaluronan and antigenic keratan sulfate. , 1993, Arthritis and rheumatism.
[23] G. Noon,et al. Decreased expression of tumor necrosis factor-alpha in failing human myocardium after mechanical circulatory support : A potential mechanism for cardiac recovery. , 1999, Circulation.
[24] J. Thornby,et al. Natural variability of circulating levels of cytokines and cytokine receptors in patients with heart failure: implications for clinical trials. , 1999, Journal of the American College of Cardiology.
[25] H. Friedman,et al. Tumor necrosis factor induction by Candida albicans from human natural killer cells and monocytes. , 1988, Journal of immunology.
[26] W. Sandborn. A controlled trial of anti-tumor necrosis factor alpha antibody for Crohn's disease. , 1997, Gastroenterology.
[27] H. Oral,et al. Proinflammatory cytokine levels in patients with depressed left ventricular ejection fraction: a report from the Studies of Left Ventricular Dysfunction (SOLVD). , 1996, Journal of the American College of Cardiology.
[28] G. MacGowan,et al. Circulating interleukin-6 in severe heart failure. , 1997, The American journal of cardiology.
[29] D. Mann,et al. Soluble TNF binding proteins modulate the negative inotropic properties of TNF-alpha in vitro. , 1995, The American journal of physiology.
[30] B. Chandrasekar,et al. Chronic beta-adrenergic stimulation induces myocardial proinflammatory cytokine expression. , 2000, Circulation.
[31] A. Feldman,et al. Sex-related survival differences in murine cardiomyopathy are associated with differences in TNF-receptor expression. , 2000, The Journal of clinical investigation.
[32] Yy Li,et al. Matrix metalloproteinases in pathophysiology and treatment of heart failure , 2001, The Lancet.
[33] M. Yacoub,et al. Elevated Tumor Necrosis Factor-&agr; and Interleukin-6 in Myocardium and Serum of Malfunctioning Donor Hearts , 2000, Circulation.
[34] T. van der Poll,et al. Epinephrine inhibits tumor necrosis factor-alpha and potentiates interleukin 10 production during human endotoxemia. , 1996, The Journal of clinical investigation.
[35] H. Fillit,et al. Elevated circulating levels of tumor necrosis factor in severe chronic heart failure. , 1990, The New England journal of medicine.
[36] S. Anker,et al. Plasma Cytokine Parameters and Mortality in Patients With Chronic Heart Failure , 2000, Circulation.
[37] A. Koretsky,et al. Dilated Cardiomyopathy in Transgenic Mice With Cardiac-Specific Overexpression of Tumor Necrosis Factor-α , 1997 .
[38] M. Lambert,et al. Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-α , 1997, Nature.
[39] A. Matsumori,et al. Cytokine gene expression after myocardial infarction in rat hearts: possible implication in left ventricular remodeling. , 1998, Circulation.
[40] P. Ladenson,et al. Reversible alterations in myocardial gene expression in a young man with dilated cardiomyopathy and hypothyroidism. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[41] M. Zile,et al. Matrix metalloproteinase inhibition during the development of congestive heart failure : effects on left ventricular dimensions and function. , 1999, Circulation research.
[42] R L Kassel,et al. An endotoxin-induced serum factor that causes necrosis of tumors. , 1975, Proceedings of the National Academy of Sciences of the United States of America.
[43] A. Feldman,et al. Downregulation of Matrix Metalloproteinases and Reduction in Collagen Damage in the Failing Human Heart After Support With Left Ventricular Assist Devices , 2001, Circulation.
[44] E. Tindall,et al. Treatment of rheumatoid arthritis with a recombinant human tumor necrosis factor receptor (p75)-Fc fusion protein. , 1997, The New England journal of medicine.
[45] J. O’dell. TNF-α Inhibition: The Need for a Tumor Necrosis Factor Thermostat , 2001 .
[46] Nicole Nelson,et al. A metalloproteinase disintegrin that releases tumour-necrosis factor-α from cells , 1997, Nature.
[47] D. Wallach,et al. Cytoplasmic truncation of the p55 tumour necrosis factor (TNF) receptor abolishes signalling, but not induced shedding of the receptor. , 1992, The EMBO journal.
[48] L. Vaca,et al. Cellular basis for the negative inotropic effects of tumor necrosis factor-alpha in the adult mammalian heart. , 1993, The Journal of clinical investigation.
[49] I. Komuro,et al. Peroxisome Proliferator–Activated Receptor Activators Inhibit Lipopolysaccharide-Induced Tumor Necrosis Factor-α Expression in Neonatal Rat Cardiac Myocytes , 2000 .
[50] F. Stüber,et al. A genomic polymorphism within the tumor necrosis factor locus influences plasma tumor necrosis factor-alpha concentrations and outcome of patients with severe sepsis. , 1996, Critical care medicine.
[51] C. Beaumont,et al. Role for NF-κB in the Regulation of Ferritin H by Tumor Necrosis Factor-α (*) , 1995, The Journal of Biological Chemistry.
[52] A. Matsumori,et al. Modulation of cytokine production and protection against lethal endotoxemia by the cardiac glycoside ouabain. , 1997, Circulation.
[53] O. Febo,et al. Tumor necrosis factor soluble receptors in patients with various degrees of congestive heart failure. , 1995, Circulation.
[54] Simon C Watkins,et al. Myocardial extracellular matrix remodeling in transgenic mice overexpressing tumor necrosis factor alpha can be modulated by anti-tumor necrosis factor alpha therapy. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[55] T. Ohtsuka,et al. Effect of beta-blockers on circulating levels of inflammatory and anti-inflammatory cytokines in patients with dilated cardiomyopathy. , 2001, Journal of the American College of Cardiology.
[56] S. Reis,et al. Estrogen is associated with improved survival in aging women with congestive heart failure: analysis of the vesnarinone studies. , 2000, Journal of the American College of Cardiology.
[57] M. Satoh,et al. Expression of tumor necrosis factor-alpha--converting enzyme and tumor necrosis factor-alpha in human myocarditis. , 2000, Journal of the American College of Cardiology.
[58] J. Woessner,et al. Remodeling of human myocardial collagen in idiopathic dilated cardiomyopathy. Role of metalloproteinases and pyridinoline cross-links. , 1996, The American journal of pathology.
[59] Simon C Watkins,et al. Mitochondrial Abnormalities in Tumor Necrosis Factor-&agr;–Induced Heart Failure Are Associated With Impaired DNA Repair Activity , 2001, Circulation.
[60] A. Feldman,et al. MMP inhibition modulates TNF-alpha transgenic mouse phenotype early in the development of heart failure. , 2002, American journal of physiology. Heart and circulatory physiology.
[61] Simon C Watkins,et al. Effects of soluble TNF receptor treatment on lipopolysaccharide-induced myocardial cytokine expression. , 2001, American journal of physiology. Heart and circulatory physiology.
[62] G. Schreiner,et al. Mechanism of cytokine inhibition of beta-adrenergic agonist stimulation of cyclic AMP in rat cardiac myocytes. Impairment of signal transduction. , 1990, Circulation research.
[63] H. Oral,et al. Hemodynamic regulation of tumor necrosis factor-alpha gene and protein expression in adult feline myocardium. , 1997, Circulation research.
[64] D. Wallach,et al. Two tumor necrosis factor-binding proteins purified from human urine. Evidence for immunological cross-reactivity with cell surface tumor necrosis factor receptors. , 1990, The Journal of biological chemistry.
[65] S. Watanabe,et al. Inhibition of tumor necrosis factor-alpha and interleukin-1-beta production by beta-adrenoceptor agonists from lipopolysaccharide-stimulated human peripheral blood mononuclear cells. , 1997, Pharmacology.
[66] A. Peaceman,et al. Tumor necrosis factor-alpha is elevated in plasma and amniotic fluid of patients with severe preeclampsia. , 1994, American journal of obstetrics and gynecology.
[67] D. Mann,et al. Tumor Necrosis Factor-α and Tumor Necrosis Factor Receptors in the Failing Human Heart , 1996 .
[68] I. Wicks,et al. Severe inflammatory arthritis and lymphadenopathy in the absence of TNF. , 2001, The Journal of clinical investigation.
[69] D. Mann,et al. Nitric Oxide Provokes Tumor Necrosis Factor-&agr; Expression in Adult Feline Myocardium Through a cGMP-Dependent Pathway , 2000, Circulation.
[70] B. Beutler,et al. Tumor necrosis factor (cachectin) is an endogenous pyrogen and induces production of interleukin 1 , 1986, The Journal of experimental medicine.
[71] E. Nilsson,et al. Isolation and characterization of a tumor necrosis factor binding protein from urine , 1989, European journal of haematology.
[72] M. Seishima,et al. Tumor necrosis factor-alpha (TNF-alpha) plays a protective role in acute viralmyocarditis in mice: A study using mice lacking TNF-alpha. , 2001, Circulation.
[73] Gilla Kaplan,et al. Selection of Novel Analogs of Thalidomide with Enhanced Tumor Necrosis Factor α Inhibitory Activity , 1996, Molecular medicine.
[74] A. Feldman,et al. Interleukin-1 beta inhibits phospholamban gene expression in cultured cardiomyocytes. , 1997, Circulation research.
[75] A. Feldman,et al. Proinflammatory cytokines regulate tissue inhibitors of metalloproteinases and disintegrin metalloproteinase in cardiac cells. , 1999, Cardiovascular research.
[76] D. Fukai,et al. Interleukin-6 spillover in the peripheral circulation increases with the severity of heart failure, and the high plasma level of interleukin-6 is an important prognostic predictor in patients with congestive heart failure. , 1998, Journal of the American College of Cardiology.
[77] S. Basili,et al. Simvastatin inhibits the monocyte expression of proinflammatory cytokines in patients with hypercholesterolemia. , 2000, Journal of the American College of Cardiology.
[78] J. Larrick,et al. Cytotoxic mechanism of tumor necrosis factor‐α , 1990, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[79] M. Lovett,et al. CYTOKINE GENE EXPRESSION IN REJECTING CARDIAC ALLOGRAFTS , 1992, Transplantation.
[80] M. R. Bergman,et al. Pharmacological modulation of myocardial tumor necrosis factor alpha production by phosphodiesterase inhibitors. , 1996, The Journal of pharmacology and experimental therapeutics.
[81] D. Grennan,et al. Increased frequency of the uncommon allele of a tumour necrosis factor alpha gene polymorphism in rheumatoid arthritis and systemic lupus erythematosus. , 1995, Disease markers.
[82] F. Clubb,et al. Pathophysiologically relevant concentrations of tumor necrosis factor-alpha promote progressive left ventricular dysfunction and remodeling in rats. , 1998, Circulation.
[83] J. Aliberti,et al. Trypanosoma cruzi–Infected Cardiomyocytes Produce Chemokines and Cytokines That Trigger Potent Nitric Oxide–Dependent Trypanocidal Activity , 2000, Circulation.
[84] M. Entman,et al. Tumor Necrosis Factor-α Provokes a Hypertrophic Growth Response in Adult Cardiac Myocytes , 1997 .
[85] T. Mak,et al. Low-molecular-weight tumor necrosis factor receptor p55 controls induction of autoimmune heart disease. , 1997, Circulation.
[86] P. Robbins,et al. Soluble tumor necrosis factor receptor abrogates myocardial inflammation but not hypertrophy in cytokine-induced cardiomyopathy. , 2000, Circulation.
[87] J. Vilček,et al. Tumor necrosis factor. New insights into the molecular mechanisms of its multiple actions. , 1991, The Journal of biological chemistry.
[88] A. Demetris,et al. Cardiac-specific overexpression of tumor necrosis factor-alpha causes lethal myocarditis in transgenic mice. , 1997, Journal of cardiac failure.
[89] P. Vassalli,et al. The pathophysiology of tumor necrosis factors. , 1992, Annual review of immunology.
[90] P. Robbins,et al. Adenoviral-directed overexpression of soluble tumor necrosis factor receptors reverses myocarditis in transgenic mice with congestive heart failure , 1998 .
[91] A. Matsumori,et al. Amiodarone inhibits production of tumor necrosis factor-alpha by human mononuclear cells: a possible mechanism for its effect in heart failure. , 1997, Circulation.
[92] G Baumgarten,et al. Endogenous tumor necrosis factor protects the adult cardiac myocyte against ischemic-induced apoptosis in a murine model of acute myocardial infarction. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[93] G. Schreiner,et al. Interleukin 1 and tumor necrosis factor inhibit cardiac myocyte beta-adrenergic responsiveness. , 1989, Proceedings of the National Academy of Sciences of the United States of America.
[94] B. Beutler,et al. Unraveling function in the TNF ligand and receptor families. , 1994, Science.
[95] A. Feldman,et al. Anti–Tumor Necrosis Factor-&agr; Antibody Limits Heart Failure in a Transgenic Model , 2001, Circulation.
[96] M. Kinoshita,et al. Angiotensin II type 1 receptor antagonist decreases plasma levels of tumor necrosis factor alpha, interleukin-6 and soluble adhesion molecules in patients with chronic heart failure. , 2000, Journal of the American College of Cardiology.
[97] J. Sadoshima. Cytokine actions of angiotensin II. , 2000, Circulation research.
[98] M. Entman,et al. Decreased Expression of Tumor Necrosis Factor-&agr; and Regression of Hypertrophy After Nonsurgical Septal Reduction Therapy for Patients With Hypertrophic Obstructive Cardiomyopathy , 2001, Circulation.
[99] R. Gentz,et al. Two human TNF receptors have similar extracellular, but distinct intracellular, domain sequences. , 1990, Cytokine.