Finite element analysis of particle motion in steady inspiratory airflow

Abstract To accurately model the inhaled particle motion, equations governing particle trajectories in carrier flow are solved together with the Navier–Stokes equations. Under the relatively dilute particle condition in the mixture, equations for two phases are coupled through the interface drag shown in the solid-phase momentum equations. The present study investigates bifurcation flow in the human central airway using the finite element method. In the gas phase, we employ the biquadratic streamline upwind Petrov–Galerkin finite element model to simulate the incompressible air flow. To solve the equations of motion for the inhaled particles, we apply another biquadratic streamline upwind finite element model. A feature common to two models applied to each phase of equations is that both of them provide nodally exact solutions to the convection–diffusion and the convection–reaction equations, which are prototype equations for the gas-phase and the solid-phase equations, respectively. In two dimensions, both models have ability to introduce physically meaningful artificial damping terms solely in the streamline direction. With these terms added to the formulation, the discrete system is enhanced without compromising the numerical diffusion error. Tests on inspiratory problem were conducted, and the results are presented, with an emphasis on the discussion of particle motion.

[1]  Tony W. H. Sheu,et al.  A finite element study of the blood flow in total cavopulmonary connection , 1999 .

[2]  T. Hughes,et al.  Streamline upwind/Petrov-Galerkin formulations for convection dominated flows with particular emphasis on the incompressible Navier-Stokes equations , 1990 .

[3]  J. Fathikalajahi,et al.  Prediction of particle deposition from a turbulent stream around a surface-mounted ribbon , 1998 .

[4]  T. Hughes,et al.  A new finite element formulation for computational fluid dynamics: V. Circumventing the Babuscka-Brezzi condition: A stable Petrov-Galerkin formulation of , 1986 .

[5]  Ted B. Martonen,et al.  A numerical study of particle motion within the human larynx and trachea , 1999 .

[6]  Jim Douglas,et al.  An absolutely stabilized finite element method for the stokes problem , 1989 .

[7]  Karan S. Surana,et al.  p‐version least squares finite element formulation for two‐dimensional, incompressible fluid flow , 1994 .

[8]  P. Saffman The lift on a small sphere in a slow shear flow , 1965, Journal of Fluid Mechanics.

[9]  G. Degrez,et al.  Numerical modeling of steady inspiratory airflow through a three-generation model of the human central airways. , 1997, Journal of biomechanical engineering.

[10]  K. Kuo,et al.  Transient combustion in mobile gas-permeable propellants , 1976 .

[11]  A. Kuhl,et al.  Analysis of Combustion Processes in a Mobile Granular Propellant Bed , 1993 .

[12]  T. Martonen,et al.  Deposition Patterns of Aerosolized Drugs Within Human Lungs: Effects of Ventilatory Parameters , 1993, Pharmaceutical Research.

[13]  T. Sheu,et al.  ANALYSIS OF COMBUSTION PROCESSES IN A GUN INTERIOR BALLISTICS , 1995 .

[14]  Gérard Degrez,et al.  Experimental and numerical investigation of flows in bifurcations within lung airways. , 1994 .

[15]  Numerical study of two-dimensional solid-gas combustion through granulated propellants , 1995 .

[16]  G. Ahmadi,et al.  Particle Transport and Deposition in a Hot-Gas Cleanup Pilot Plant , 1998 .

[17]  O. Axelsson,et al.  Analytical and Numerical Approaches to Asymptotic Problems in Analysis. , 1983 .

[18]  R. Clift,et al.  Motion of entrained particles in gas streams , 1971 .

[19]  I. Babuska Error-bounds for finite element method , 1971 .

[20]  Uno Nävert,et al.  An Analysis of some Finite Element Methods for Advection-Diffusion Problems , 1981 .

[21]  T. Hughes,et al.  The Galerkin/least-squares method for advective-diffusive equations , 1988 .

[22]  S. Mittal,et al.  Incompressible flow computations with stabilized bilinear and linear equal-order-interpolation velocity-pressure elements , 1992 .

[23]  T. Sheu,et al.  A PETROV-GALERKIN FORMULATION FOR INCOMPRESSIBLE FLOW AT HIGH REYNOLDS NUMBER , 1995 .

[24]  T. Chang,et al.  Lung effect on the hemodynamics in pulmonary artery , 2001 .

[25]  Vijay Sonnad,et al.  Least-squares solution of incompressible navier-stokes equations with the p-version of finite elements , 1994, Computational Mechanics.

[26]  Thomas J. R. Hughes,et al.  The Stokes problem with various well-posed boundary conditions - Symmetric formulations that converge for all velocity/pressure spaces , 1987 .

[27]  F. Brezzi On the existence, uniqueness and approximation of saddle-point problems arising from lagrangian multipliers , 1974 .