The continuous synthesis of ε-caprolactam from 6-aminocapronitrile in high-temperature water

Caprolactam (CPL) is a widely used chemical intermediate for the production of Nylon-6. However, existing synthetic routes in industry have severe drawbacks. The development on the synthesis of CPL from 6-aminocapronitrile (ACN), using near- and supercritical water as the solvent, reactant and catalyst, is described in this paper. The two-step reaction (hydrolysis and cyclization) to produce CPL is combined in a single process, by using a continuous-flow system. Effects of pressure, temperature, residence time and the concentration of ACN were studied. The high-temperature high-pressure environment possesses unique properties which result in very efficient catalysis. The overall CPL yield reaches 90% within a short residence time (<2 min).

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