Further pharmacological characterization of [3H]idazoxan binding sites in rat brain: evidence for predominant labeling ofα 2-adrenergic receptors

[1]  J. Wikberg,et al.  Delineation of three pharmacological subtypes of α2‐adrenoceptor in the rat kidney , 1991 .

[2]  E. Kalso,et al.  FLFQPQRF-amide modulatesα2-adrenergic antinociception in the rat dorsal horn in vivo , 1991, Brain Research.

[3]  J. Wikberg,et al.  Delineation of rat kidney α2A- and α2B-adrenoeeptors with [3H]RX821002 radiollgand binding: computer modelling reveals that guanfacine is an α2A-selective compound , 1991 .

[4]  F. Tesson,et al.  Identification of an imidazoline-guanidinium receptive site in mitochondria from rabbit cerebral cortex. , 1991, European journal of pharmacology.

[5]  J. Harrison,et al.  Pharmacological characterization of rat alpha 2-adrenergic receptors. , 1991, Molecular pharmacology.

[6]  C. Felder,et al.  The rat α2‐C4 adrenergic receptor gene encodes a novel pharmacological subtype , 1991 .

[7]  D. Langin,et al.  Identification of α2-adrenoceptors and non-adrenergic idazoxan binding sites in rabbit colon epithelial cells , 1990 .

[8]  T. Branchek,et al.  Cloning, expression, and pharmacological characterization of a human alpha 2B-adrenergic receptor. , 1990, Molecular pharmacology.

[9]  S. Southwick,et al.  Altered platelet alpha 2-adrenergic receptor binding sites in borderline personality disorder. , 1990, The American journal of psychiatry.

[10]  M. Caron,et al.  Expansion of the alpha 2-adrenergic receptor family: cloning and characterization of a human alpha 2-adrenergic receptor subtype, the gene for which is located on chromosome 2. , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[11]  J. Wikberg,et al.  Further Characterization of the Guinea Pig Cerebral Cortex Idazoxan Receptor: Solubilization, Distinction from the Imidazole Site, and Demonstration of Cirazoline as an Idazoxan Receptor‐Selective Drug , 1990, Journal of neurochemistry.

[12]  D. Langin,et al.  Binding of [3H]idazoxan and of its methoxy derivative [3H] RX821002 in human fat cells: [3H]idazoxan but not [3H] RX821002 labels additional non-alpha 2-adrenergic binding sites. , 1990, Molecular pharmacology.

[13]  M. Spedding,et al.  α2‐Adrenoceptor subtypes and imidazoline‐like binding sites in the rat brain , 1990 .

[14]  D. Reis,et al.  Role of imidazole receptors in the vasodepressor response to clonidine analogs in the rostral ventrolateral medulla. , 1990, The Journal of pharmacology and experimental therapeutics.

[15]  M. Spedding,et al.  Heterogeneity of α2‐adrenoceptors in rat cortex but not human platelets can be defined by 8‐OH‐DPAT, RU 24969 and methysergide , 1990, British journal of pharmacology.

[16]  R. Neubig,et al.  Nonadrenergic [3H]idazoxan binding sites are physically distinct from alpha 2-adrenergic receptors. , 1990, Molecular pharmacology.

[17]  P. Insel,et al.  Are there multiple imidazoline binding sites? , 1989, Trends in pharmacological sciences.

[18]  R. Graham,et al.  Characterization of an imidazoline/guanidinium receptive site distinct from the alpha 2-adrenergic receptor. , 1989, The Journal of biological chemistry.

[19]  J. De Keyser,et al.  High affinity binding of 3H rauwolscine and 3H RX781094 to alpha 2 adrenergic receptors and non-stereoselective sites in human and rabbit brain cortex membranes. , 1989, Biochemical pharmacology.

[20]  D. Langin,et al.  [3H]Idazoxan binding at non-α2-adrenoceptors in rabbit adipocyte membranes , 1989 .

[21]  J. Wikberg High affinity binding of idazoxan to a non-catecholaminergic binding site in the central nervous system: description of a putative idazoxan-receptor. , 1989, Pharmacology & toxicology.

[22]  D. Bylund Sub types of α2-adrenoceptors: Pharmacological and molecular biological evidence converg , 1988 .

[23]  W. Klemm,et al.  Alpha noradrenergic agonists promote catalepsy in the mouse , 1988, Pharmacology Biochemistry and Behavior.

[24]  M. Caron,et al.  Cloning and expression of a human kidney cDNA for an alpha 2-adrenergic receptor subtype. , 1988, Proceedings of the National Academy of Sciences of the United States of America.

[25]  D. Bylund,et al.  Alpha-2A and alpha-2B adrenergic receptor subtypes: antagonist binding in tissues and cell lines containing only one subtype. , 1988, The Journal of pharmacology and experimental therapeutics.

[26]  G. Brüning,et al.  Quantitative autoradiographic localization of α 2-antagonist binding sites in rat brain using [3H]idazoxan , 1987, Neuroscience Letters.

[27]  M. Caron,et al.  Cloning, sequencing, and expression of the gene coding for the human platelet alpha 2-adrenergic receptor. , 1987, Science.

[28]  F. Leslie,et al.  Pharmacological evidence for alpha-2 adrenoceptor heterogeneity: differential binding properties of [3H]rauwolscine and [3H]idazoxan in rat brain. , 1987, The Journal of pharmacology and experimental therapeutics.

[29]  S. Loughlin,et al.  Anatomical evidence for alpha-2 adrenoceptor heterogeneity: differential autoradiographic distributions of [3H]rauwolscine and [3H]idazoxan in rat brain. , 1987, The Journal of pharmacology and experimental therapeutics.

[30]  D. Reis,et al.  An endogenous clonidine-like substance binds preferentially to imidazole binding sites in the ventrolateral medulla labelled by 3H-para-aminoclonidine , 1986 .

[31]  P. Goldman-Rakic,et al.  Alpha 2-adrenergic mechanisms in prefrontal cortex associated with cognitive decline in aged nonhuman primates. , 1985, Science.

[32]  D. Bylund Heterogeneity of alpha-2 adrenergic receptors , 1985, Pharmacology Biochemistry and Behavior.

[33]  T. Yaksh Pharmacology of spinal adrenergic systems which modulate spinal nociceptive processing , 1985, Pharmacology Biochemistry and Behavior.

[34]  G A McPherson,et al.  A practical computer-based approach to the analysis of radioligand binding experiments. , 1983, Computer programs in biomedicine.

[35]  H. Y. Kwa,et al.  Characterization of alpha-adrenoceptors participating in the central hypotensive and sedative effects of clonidine using yohimbine, rauwolscine and corynanthine. , 1981, European journal of pharmacology.

[36]  D Rodbard,et al.  Ligand: a versatile computerized approach for characterization of ligand-binding systems. , 1980, Analytical biochemistry.