Urinary metabolites of histamine and leukotrienes before and after placebo‐controlled challenge with ASA and food additives in chronic urticaria patients

Background: The recovery of mediator metabolites from urine has the potential to provide a rapid, safe, and easily available index of release of mediators. We aimed to determine urinary metabolites of both histamine and leukotrienes (LTs) in patients affected by chronic urticaria (CU).

[1]  R. Corrocher,et al.  Efficacy of leukotriene receptor antagonist in chronic urticaria. A double‐blind, placebo‐controlled comparison of treatment with montelukast and cetirizine in patients with chronic urticaria with intolerance to food additive and/or acetylsalicylic acid , 2001, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

[2]  J. Bousquet,et al.  A revised nomenclature for allergy: An EAACI position statement from the EAACI nomenclature task force , 2001, Allergy.

[3]  T. Zuberbier,et al.  Increased leukotriene production by food additives in patients with atopic dermatitis and proven food intolerance , 2001, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

[4]  R. Asero Leukotriene receptor antagonists may prevent NSAID-induced exacerbations in patients with chronic urticaria. , 2000, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

[5]  M. Ellis,et al.  Successful treatment of chronic urticaria with leukotriene antagonists. , 1998, The Journal of allergy and clinical immunology.

[6]  A. Black,et al.  Anti-FcϵRI autoantibodies and basophil histamine releasability in chronic idiopathic urticaria☆☆☆★★★♢ , 1998 .

[7]  S. Spector,et al.  Antileukotrienes in chronic urticaria. , 1998, The Journal of allergy and clinical immunology.

[8]  Horio,et al.  Aspirin‐sensitive urticaria: provocation with a leukotriene receptor antagonist , 1998, The British journal of dermatology.

[9]  C. Caruso,et al.  Blood eosinophils and serum eosinophil cationic protein in patients with acute and chronic urticaria , 1996, Mediators of inflammation.

[10]  G. Bonsignore,et al.  Urinary leukotriene E4 in the assessment of nocturnal asthma. , 1996, The Journal of allergy and clinical immunology.

[11]  E. Israel,et al.  Diurnal variation of urinary leukotriene E4 and histamine excretion rates in normal subjects and patients with mild-to-moderate asthma. , 1995, The Journal of allergy and clinical immunology.

[12]  E. Pastorello,et al.  Evaluating new tests for the diagnosis of food allergy , 1995, Allergy.

[13]  G. Vighi,et al.  III. Definition of adverse reactions to food , 1995 .

[14]  S. Dahlén,et al.  Urinary excretion of leukotriene E4 and 11-dehydro-thromboxane B2 in response to bronchial provocations with allergen, aspirin, leukotriene D4, and histamine in asthmatics. , 1992, The American review of respiratory disease.

[15]  L. Schwartz,et al.  Mast cells and their role in urticaria. , 1991, Journal of the American Academy of Dermatology.

[16]  S. Tarlo,et al.  Chronic Urticaria , 1991, International journal of dermatology.

[17]  A. Ford-hutchinson,et al.  Urinary leukotriene E4 concentrations increase after aspirin challenge in aspirin-sensitive asthmatic subjects. , 1991, The American review of respiratory disease.

[18]  N. Voelkel,et al.  Leukotriene E4 elimination and metabolism in normal human subjects. , 1990, The Journal of biological chemistry.

[19]  R. Urbanek,et al.  Determination of N-methylhistamine in urine as an indicator of histamine release in immediate allergic reactions. , 1990, The Journal of allergy and clinical immunology.

[20]  Robert A. Lewis,et al.  Leukotrienes and other products of the 5-lipoxygenase pathway. Biochemistry and relation to pathobiology in human diseases. , 1990, The New England journal of medicine.

[21]  H. Sampson,et al.  Workshop on experimental methodology for clinical studies of adverse reactions to foods and food additives. , 1990, The Journal of allergy and clinical immunology.

[22]  P. O'Byrne,et al.  Urinary leukotriene E4 levels during early and late asthmatic responses. , 1990, The Journal of allergy and clinical immunology.

[23]  S. Marney,et al.  Allergen-stimulated release of thromboxane A2 and leukotriene E4 in humans. Effect of indomethacin. , 1990, The American review of respiratory disease.

[24]  A. Szczeklik Adverse reactions to aspirin and nonsteroidal anti-inflammatory drugs. , 1987, Annals of allergy.

[25]  A. Sala,et al.  Study of mediators of anaphylaxis in nasal wash fluids after aspirin and sodium metabisulfite nasal provocation in intolerant rhinitic patients. , 1987, Annals of allergy.

[26]  P. Sterk,et al.  The excretion of leukotriene E4 into urine following inhalation of leukotriene D4 by human individuals. , 1987, Biochemical and biophysical research communications.

[27]  L. Kaijser,et al.  In vivo metabolism of leukotriene C4 in man: urinary excretion of leukotriene E4. , 1985, Biochemical and biophysical research communications.

[28]  C. May Are confusion and controversy about food hypersensitivity really necessary? , 1985, The Journal of allergy and clinical immunology.

[29]  K. Frank Austen,et al.  Local Effects of Synthetic Leukotrienes (LTC4, LTD4, and LTB4) in Human Skin , 1983 .

[30]  M. Mayer,et al.  Revised nomenclature. , 1980, Journal of immunology.

[31]  B. Slavin Fundamentals of Clinical Chemistry , 1977 .

[32]  G. Settipane,et al.  Aspirin intolerance. III. Subtypes, familial occurence, and cross-reactivity with tartarazine. , 1975, The Journal of allergy and clinical immunology.

[33]  H. Doeglas Reactions to aspirin and food additives in patients with chronic urticaria, including the physical urticarias * , 1975, The British journal of dermatology.

[34]  G. Michaëlsson,et al.  Urticaria induced by preservatives and dye additives in food and drugs , 1973, The British journal of dermatology.

[35]  O. Zetterström,et al.  Urticaria and asthma induced by food-and-drug additives in patients with aspirin hypersensitivity. , 1972, The Journal of allergy and clinical immunology.

[36]  Lockey Sd Reactions to hidden agents in foods, beverages and drugs. , 1971 .

[37]  R. Simon,et al.  Mast cells, basophils, and immunoglobulin E. , 1996 .

[38]  G. Vighi,et al.  Definition of adverse reactions to food. , 1995, Allergy.

[39]  R. Patterson,et al.  The effect of the oral leukotriene antagonist, ICI 204,219, on leukotriene D4 and histamine-induced cutaneous vascular reactions in man. , 1991, The Journal of allergy and clinical immunology.

[40]  E. Corey,et al.  Local effects of synthetic leukotrienes (LTC4, LTD4, LTE4, and LTB4) in human skin. , 1983, The Journal of investigative dermatology.

[41]  D. Ruano-Gil,et al.  Human embryo (12 mm) with mesohydronephrosis and ureterohydronephrosis. , 1975, Acta anatomica.

[42]  S. Lockey Reactions to hidden agents in foods, beverages and drugs. , 1971, Annals of allergy.

[43]  N. Tietz Fundamentals of Clinical Chemistry , 1970 .