Crossing the blood-brain-barrier with transferrin conjugated carbon dots: A zebrafish model study.

[1]  Dan Qu,et al.  Self-Targeting Fluorescent Carbon Dots for Diagnosis of Brain Cancer Cells. , 2015, ACS nano.

[2]  S. Hoeppener,et al.  Synthesis and Modification of Carbon Nanomaterials utilizing Microwave Heating , 2015, Advanced materials.

[3]  R. Leblanc,et al.  Method To Determine Protein Concentration in the Protein-Nanoparticle Conjugates Aqueous Solution Using Circular Dichroism Spectroscopy. , 2015, Analytical chemistry.

[4]  Louis Wehenkel,et al.  Zebrafish Bone and General Physiology Are Differently Affected by Hormones or Changes in Gravity , 2015, PloS one.

[5]  Maria K. Lehtinen,et al.  Zebrafish cerebrospinal fluid mediates cell survival through a retinoid signaling pathway , 2015, Developmental neurobiology.

[6]  R. Leblanc,et al.  Nontoxic Carbon Dots Potently Inhibit Human Insulin Fibrillation , 2015 .

[7]  Lan Sheng,et al.  Carbon Dots with Continuously Tunable Full-Color Emission and Their Application in Ratiometric pH Sensing , 2014 .

[8]  J. Kreuter,et al.  Drug delivery to the central nervous system by polymeric nanoparticles: what do we know? , 2014, Advanced drug delivery reviews.

[9]  R. Leblanc,et al.  Aggregation of insulin at the interface. , 2014, The journal of physical chemistry. B.

[10]  Mark E. Davis,et al.  Transcytosis and brain uptake of transferrin-containing nanoparticles by tuning avidity to transferrin receptor , 2013, Proceedings of the National Academy of Sciences.

[11]  R. Watts,et al.  Developing Therapeutic Antibodies for Neurodegenerative Disease , 2013, Neurotherapeutics.

[12]  Bai Yang,et al.  Highly photoluminescent carbon dots for multicolor patterning, sensors, and bioimaging. , 2013, Angewandte Chemie.

[13]  Philip M. Kelly,et al.  Transferrin-functionalized nanoparticles lose their targeting capabilities when a biomolecule corona adsorbs on the surface. , 2013, Nature nanotechnology.

[14]  Svetlana Gelperina,et al.  Transport of drugs across the blood-brain barrier by nanoparticles. , 2012, Journal of controlled release : official journal of the Controlled Release Society.

[15]  Leonard I Zon,et al.  Hooked! Modeling human disease in zebrafish. , 2012, The Journal of clinical investigation.

[16]  Fang Liu,et al.  Conjugation of Functionalized SPIONs with Transferrin for Targeting and Imaging Brain Glial Tumors in Rat Model , 2012, PloS one.

[17]  Siew Yee Wong,et al.  Intrinsically fluorescent carbon dots with tunable emission derived from hydrothermal treatment of glucose in the presence of monopotassium phosphate. , 2011, Chemical communications.

[18]  Masahiko Sugimoto,et al.  A novel transgenic zebrafish model for blood-brain and blood-retinal barrier development , 2010, BMC Developmental Biology.

[19]  Adela C. Bonoiu,et al.  Photoluminescent Carbon Dots as Biocompatible Nanoprobes for Targeting Cancer Cells in Vitro , 2010 .

[20]  Ya‐Ping Sun,et al.  Carbon Dots as Nontoxic and High-Performance Fluorescence Imaging Agents. , 2009, The journal of physical chemistry. C, Nanomaterials and interfaces.

[21]  K. Hamad-Schifferli,et al.  Site-directed nanoparticle labeling of cytochrome c , 2009, Proceedings of the National Academy of Sciences.

[22]  D. Walsh,et al.  Protein Aggregation in the Brain: The Molecular Basis for Alzheimer’s and Parkinson’s Diseases , 2008, Molecular medicine.

[23]  Kyu-Won Kim,et al.  Functional and developmental analysis of the blood–brain barrier in zebrafish , 2008, Brain Research Bulletin.

[24]  R. Dorsky,et al.  Regulation and function of Dbx genes in the zebrafish spinal cord , 2007, Developmental dynamics : an official publication of the American Association of Anatomists.

[25]  R. MacGillivray,et al.  Intrinsic fluorescence reports a global conformational change in the N-lobe of human serum transferrin following iron release. , 2007, Biochemistry.

[26]  Robert Langer,et al.  Targeted nanoparticles for cancer therapy , 2007 .

[27]  Gustavo Helguera,et al.  The transferrin receptor part II: targeted delivery of therapeutic agents into cancer cells. , 2006, Clinical immunology.

[28]  C. Dobson,et al.  Protein misfolding, functional amyloid, and human disease. , 2006, Annual review of biochemistry.

[29]  V. Sallinen,et al.  Modulatory neurotransmitter systems and behavior: towards zebrafish models of neurodegenerative diseases. , 2006, Zebrafish.

[30]  T. Davis,et al.  The Blood-Brain Barrier/Neurovascular Unit in Health and Disease , 2005, Pharmacological Reviews.

[31]  Latha A. Gearheart,et al.  Electrophoretic analysis and purification of fluorescent single-walled carbon nanotube fragments. , 2004, Journal of the American Chemical Society.

[32]  Hongzhe Sun,et al.  Targeted Drug Delivery via the Transferrin Receptor-Mediated Endocytosis Pathway , 2002, Pharmacological Reviews.

[33]  E. Morgan,et al.  Transferrin and Transferrin Receptor Function in Brain Barrier Systems , 2000, Cellular and Molecular Neurobiology.

[34]  W. Pardridge,et al.  Genetically engineered brain drug delivery vectors: cloning, expression and in vivo application of an anti-transferrin receptor single chain antibody-streptavidin fusion gene and protein. , 1999, Protein engineering.

[35]  R. Fine,et al.  Receptor-mediated endocytosis of transferrin at the blood-brain barrier. , 1993, Journal of cell science.

[36]  T. Reese,et al.  JUNCTIONS BETWEEN INTIMATELY APPOSED CELL MEMBRANES IN THE VERTEBRATE BRAIN , 1969, The Journal of cell biology.

[37]  Y. Chen,et al.  A Multitheragnostic Nanobubble System to Induce Blood–Brain Barrier Disruption with Magnetically Guided Focused Ultrasound , 2015, Advanced materials.

[38]  W. Pardridge The blood-brain barrier: Bottleneck in brain drug development , 2005, NeuroRx : the journal of the American Society for Experimental NeuroTherapeutics.

[39]  E. Hansson,et al.  Astrocyte–endothelial interactions at the blood–brain barrier , 2006, Nature Reviews Neuroscience.

[40]  W. Pardridge Why is the global CNS pharmaceutical market so under-penetrated? , 2002, Drug discovery today.

[41]  L. Rubin,et al.  The cell biology of the blood-brain barrier. , 1999, Annual review of neuroscience.