Dramatic effect of the anomeric configuration on the thermal stability of duplex formed between novel dodecathymidine phosphoramidate (PNH2) and complementary DNA and RNA strands

[1]  B. Rayner,et al.  Oligodeoxynucleoside phosphoramidates (P-NH2): synthesis and thermal stability of duplexes with DNA and RNA targets. , 1996, Nucleic acids research.

[2]  C. Stein,et al.  Antisense oligodeoxynucleotides as clinical therapeutic agents. , 1996, Cancer investigation.

[3]  G. Zon,et al.  Antisense oligonucleotides in solution or encapsulated in immunoliposomes inhibit replication of HIV-1 by several different mechanisms. , 1994, Nucleic acids research.

[4]  J. C. Martin,et al.  Current concepts in antisense drug design. , 1993, Journal of medicinal chemistry.

[5]  Stanley T. Crooke,et al.  Antisense Research and Applications , 1993 .

[6]  B. Sproat,et al.  Comparative evaluation of seven oligonucleotide analogues as potential antisense agents. , 1993, Journal of medicinal chemistry.

[7]  R. Letsinger,et al.  Oxalyl-CPG: a labile support for synthesis of sensitive oligonucleotide derivatives. , 1991, Nucleic acids research.

[8]  B. Rayner,et al.  α-DNA IX: parallel annealing of α-anomeric oligodeoxyribonucleotides to natural mRNA is required for interference in RNase H mediated hydrolysis and reverse transcription , 1989 .

[9]  N. Thuong,et al.  Rate of degradation of [α]- and [β]-oligodeoxynucleotides in Xenopus oocytes. Implications for anti-messenger strategies , 1987 .

[10]  J. Lown,,et al.  α-DNA-V. Parallel annealing, handedness and conformation of the duplex of the unnatural α-hexadeoxyribonucleotide α-[d(CpApTpGpCpG)] with its β-complement β-[d(GpTpApCpGpC)] deduced from high field 1H-NMR , 1987 .

[11]  C. Paoletti,et al.  α-DNA II. Synthesis of unnatural α-anomeric oligodeoxyribonucleotides containing the four usual bases and study of their substrate activities for nucleases , 1987 .

[12]  Brian C. Froehler,et al.  Synthesis of DNA via deoxynucleoside H-phosphonate intermediates , 1986, Nucleic Acids Res..

[13]  J. Lown,,et al.  α-DNA I. Synthesis, characterization by high field 1H-NMR, and base-pairing properties of the unnatural hexadeoxyribonudeotide α-[d(CpCpTpTpCpC)] with its complement β-[d(GpGpApApGpG)] , 1986 .

[14]  B. Froehler Deoxynucleoside H-Phosphonate diester intermediates in the synthesis of internucleotide phosphate analogues , 1986 .

[15]  A. Simoncsits,et al.  On the stability of phosphodiester-amide internucleotide bond , 1982 .