WGS-based telomere length analysis in Dutch family trios implicates stronger maternal inheritance and a role for RRM1 gene

[1]  A. Aviv,et al.  Paternal Age and Transgenerational Telomere Length Maintenance: A Simulation Model , 2019, Scientific Reports.

[2]  N. Funel,et al.  Genetic determinants of telomere length and risk of pancreatic cancer: A PANDoRA study , 2017, International journal of cancer.

[3]  T. Lange.  Shelterin-Mediated Telomere Protection , 2018 .

[4]  D. Schadendorf,et al.  Telomere length, telomerase reverse transcriptase promoter mutations, and melanoma risk , 2018, Genes, chromosomes & cancer.

[5]  W. März,et al.  Telomere biology and age-related diseases , 2018, Clinical chemistry and laboratory medicine.

[6]  J. Meeker,et al.  Sex Differences in Telomere Length Are Not Mediated by Sex Steroid Hormones or Body Size in Early Adolescence , 2018, Gender and the Genome.

[7]  Yunliu Liang,et al.  Prognostic value of ribonucleotide reductase subunit M1 (RRM1) in non-small cell lung cancer: A meta-analysis. , 2018, Clinica chimica acta; international journal of clinical chemistry.

[8]  C. Kuzawa,et al.  The paternal age at conception effect on offspring telomere length: mechanistic, comparative and adaptive perspectives , 2018, Philosophical Transactions of the Royal Society B: Biological Sciences.

[9]  J. Shay,et al.  Long-range telomere regulation of gene expression: Telomere looping and telomere position effect over long distances (TPE-OLD). , 2018, Differentiation; research in biological diversity.

[10]  M. Kupiec,et al.  Rnr1’s role in telomere elongation cannot be replaced by Rnr3: a role beyond dNTPs? , 2018, Current Genetics.

[11]  J. Kriegsmann,et al.  Expression of ERCC1, RRM1, TUBB3 in correlation with apoptosis repressor ARC, DNA mismatch repair proteins and p53 in liver metastasis of colorectal cancer , 2017, International journal of molecular medicine.

[12]  D. Jarvis,et al.  Smoking, telomere length and lung function decline: a longitudinal population-based study , 2017, Thorax.

[13]  H. Brenner,et al.  Leukocyte Telomere Length and All-Cause, Cardiovascular Disease, and Cancer Mortality: Results From Individual-Participant-Data Meta-Analysis of 2 Large Prospective Cohort Studies , 2017, American journal of epidemiology.

[14]  J. Passos,et al.  Telomeres and Cell Senescence - Size Matters Not , 2017, EBioMedicine.

[15]  T. Lange,et al.  Telomeres in cancer: tumour suppression and genome instability , 2017, Nature Reviews Molecular Cell Biology.

[16]  Isaac S Kohane,et al.  Systematic correlation of environmental exposure and physiological and self-reported behaviour factors with leukocyte telomere length , 2016, International journal of epidemiology.

[17]  Z. Ling,et al.  RRM1 *151A>T, RRM1 ‐756T>C, and RRM1 ‐585T>Gis associated with increased susceptibility of lung cancer in Chinese patients , 2016, Cancer medicine.

[18]  Y. Kodera,et al.  Role for Daple in non‐canonical Wnt signaling during gastric cancer invasion and metastasis , 2015, Cancer Science.

[19]  Arsen Arakelyan,et al.  Quantitative trait association study for mean telomere length in the South Asian genomes , 2015, Bioinform..

[20]  M. Blasco,et al.  Replicating through telomeres: a means to an end. , 2015, Trends in biochemical sciences.

[21]  Lilit Nersisyan,et al.  Computel: Computation of Mean Telomere Length from Whole-Genome Next-Generation Sequencing Data , 2015, PloS one.

[22]  C. Franceschi,et al.  Population-specific association of genes for telomere-associated proteins with longevity in an Italian population , 2015, Biogerontology (Dordrecht).

[23]  Syed Tasleem Raza,et al.  Telomere length variations in aging and age-related diseases. , 2015, Current aging science.

[24]  F. Hu,et al.  Mediterranean diet and telomere length in Nurses’ Health Study: population based cohort study , 2014, BMJ : British Medical Journal.

[25]  Pieter B. T. Neerincx,et al.  Supplementary Information Whole-genome sequence variation , population structure and demographic history of the Dutch population , 2022 .

[26]  S. Bojesen.  Telomeres and human health , 2013, Journal of internal medicine.

[27]  T. Spector,et al.  Meta-analysis of telomere length in 19 713 subjects reveals high heritability, stronger maternal inheritance and a paternal age effect , 2013, European Journal of Human Genetics.

[28]  P. O’Reilly,et al.  Identification of seven loci affecting mean telomere length and their association with disease , 2013, Nature Genetics.

[29]  E. Susser,et al.  Telomeres shorten at equivalent rates in somatic tissues of adults , 2013, Nature Communications.

[30]  Andreas Hierholzer,et al.  Wnt/β-Catenin Signaling Regulates Telomerase in Stem Cells and Cancer Cells , 2012, Science.

[31]  C. Kuzawa,et al.  Delayed paternal age of reproduction in humans is associated with longer telomeres across two generations of descendants , 2012, Proceedings of the National Academy of Sciences.

[32]  J. Shay,et al.  Early and late steps in telomere overhang processing in normal human cells: the position of the final RNA primer drives telomere shortening. , 2012, Genes & development.

[33]  Y. Murakumo,et al.  The Dishevelled-associating protein Daple controls the non-canonical Wnt/Rac pathway and cell motility , 2012, Nature Communications.

[34]  C. Humpel,et al.  Telomere length is age-dependent and reduced in monocytes of Alzheimer patients , 2012, Experimental Gerontology.

[35]  C. Dumontet,et al.  The ribonucleotide reductase large subunit (RRM1) as a predictive factor in patients with cancer. , 2011, The Lancet. Oncology.

[36]  H. Snieder,et al.  Leukocyte telomere length in healthy Caucasian and African-American adolescents: relationships with race, sex, adiposity, adipokines, and physical activity. , 2011, The Journal of pediatrics.

[37]  Wilhelm Palm,et al.  How shelterin protects mammalian telomeres. , 2008, Annual review of genetics.

[38]  T. Spector,et al.  Offspring's Leukocyte Telomere Length, Paternal Age, and Telomere Elongation in Sperm , 2008, PLoS genetics.

[39]  F. Schmidt.  Meta-Analysis , 2008 .

[40]  Manuel A. R. Ferreira,et al.  PLINK: a tool set for whole-genome association and population-based linkage analyses. , 2007, American journal of human genetics.

[41]  M. Tarsounas,et al.  Telomere regulation and function during meiosis , 2007, Chromosome Research.

[42]  T. Maeda,et al.  Change in the telomere length distribution with age in the Japanese population , 2007, Molecular and Cellular Biochemistry.

[43]  K. Riabowol,et al.  Paternal age is positively linked to telomere length of children , 2005, Aging cell.

[44]  G. Thomas,et al.  The relative lengths of individual telomeres are defined in the zygote and strictly maintained during life , 2004, Aging cell.

[45]  G. Abecasis,et al.  Merlin—rapid analysis of dense genetic maps using sparse gene flow trees , 2002, Nature Genetics.

[46]  John D. Leeth,et al.  The Simulation Model , 1995 .

[47]  U. Klotz,et al.  Telomere length in different tissues of elderly patients , 2000, Mechanisms of Ageing and Development.

[48]  J. Shay,et al.  Hayflick, his limit, and cellular ageing , 2000, Nature Reviews Molecular Cell Biology.

[49]  G. Abecasis,et al.  A general test of association for quantitative traits in nuclear families. , 2000, American journal of human genetics.

[50]  C. Begley,et al.  Human gene for the large subunit of ribonucleotide reductase (RRM1): functional analysis of the promoter. , 1995, Genomics.

[51]  D I Boomsma,et al.  Genetic determination of telomere size in humans: a twin study of three age groups. , 1994, American journal of human genetics.

[52]  R Williams,et al.  A means to an end , 2006, British Dental Journal.