Microelectrode arrays: structures and applications

The rapidly advancing technology of microelectronics is being employed by several research groups to develop microelectrode arrays for use in life science research. The authors review the development of microelectrodes using silicon-based technology over the last decade. Silicon-based technology is applied to micromachine structures that are used as substrates for electrode arrays. The resulting microelectrodes are now being utilized in cardiac and neural mapping applications at Duke University Medical Center. Specific applications in the electrophysiology of taste and smell are presented.<<ETX>>