Membrane bioreactor using pig hepatocytes for in vitro evaluation of anti-inflammatory drugs

[1]  M. Rikimaru,et al.  Hybrid bioartificial liver in hepatic failure: preliminary clinical report. , 1987, Surgery.

[2]  P. Reddanna,et al.  Overexpression of cyclooxygenase-2 (COX-2) in human primitive neuroectodermal tumors: effect of celecoxib and rofecoxib. , 2002, Cancer letters.

[3]  Y. Sakai,et al.  Development of a new bioartificial liver module filled with porcine hepatocytes immobilized on non-woven fabric. , 1996, The International journal of artificial organs.

[4]  R. Saxton,et al.  Selective cyclooxygenase-2 inhibitor rofecoxib (vioxx) induces expression of cell cycle arrest genes and slows tumor growth in human pancreatic cancer , 2002, Journal of Gastrointestinal Surgery.

[5]  S. Fenwick,et al.  The effect of the selective cyclooxygenase-2 inhibitor rofecoxib on human colorectal cancer liver metastases. , 2003, Gastroenterology.

[6]  T. Baillie,et al.  Mechanistic studies on the reversible metabolism of rofecoxib to 5-hydroxyrofecoxib in the rat: evidence for transient ring opening of a substituted 2-furanone derivative using stable isotope-labeling techniques. , 2001, Drug metabolism and disposition: the biological fate of chemicals.

[7]  E Drioli,et al.  New modified polyetheretherketone membrane for liver cell culture in biohybrid systems: adhesion and specific functions of isolated hepatocytes. , 2004, Biomaterials.

[8]  D. Dean,et al.  The absorption, distribution, metabolism and excretion of rofecoxib, a potent and selective cyclooxygenase-2 inhibitor, in rats and dogs. , 2000, Drug metabolism and disposition: the biological fate of chemicals.

[9]  A. Bader,et al.  A Novel Full‐Scale Flat Membrane Bioreactor Utilizing Porcine Hepatocytes: Cell Viability and Tissue‐Specific Functions , 2000, Biotechnology progress.

[10]  E. Drioli,et al.  Polyethersulfone membrane biohybrid system using pig hepatocytes: Effect of diclofenac on cell biotransformation and synthetic functions , 2006 .

[11]  L. De Bartolo,et al.  Development of a hybrid liver-support device , 2002, Minimally invasive therapy & allied technologies : MITAT : official journal of the Society for Minimally Invasive Therapy.

[12]  J. Vacanti,et al.  Toward development of an implantable tissue engineered liver. , 1996, Biomaterials.

[13]  S. Levenson,et al.  New Method of Hepatocyte Transplantation and Extracorporeal Liver Support , 1986, Annals of surgery.

[14]  T. Baillie,et al.  Metabolism of rofecoxib in vitro using human liver subcellular fractions. , 2003, Drug metabolism and disposition: the biological fate of chemicals.

[15]  P. Neuhaus,et al.  Hepatocyte culture between woven capillary networks: a microscopy study. , 1994, Artificial organs.

[16]  H. Redmond,et al.  The role of COX-2 inhibitors in lung cancer. , 2002, The Annals of thoracic surgery.

[17]  T. Groth,et al.  Membranes for biohybrid liver support systems--investigations on hepatocyte attachment, morphology and growth. , 2002, Biomaterials.

[18]  J. Borlak,et al.  Development of a small-scale bioreactor for drug metabolism studies maintaining hepatospecific functions. , 1998, Xenobiotica; the fate of foreign compounds in biological systems.

[19]  V. Klimberg,et al.  Glutamine supplementation reduces glutathione levels and stimulates apoptosis in DMBA-induced mammary tumors , 2003 .

[20]  Enrico Drioli,et al.  Evaluation of cell behaviour related to physico-chemical properties of polymeric membranes to be used in bioartificial organs. , 2002, Biomaterials.

[21]  T. Baillie,et al.  The disposition and metabolism of rofecoxib, a potent and selective cyclooxygenase-2 inhibitor, in human subjects. , 2002, Drug metabolism and disposition: the biological fate of chemicals.

[22]  E. Woolf,et al.  Determination of rofecoxib, a cyclooxygenase-2 specific inhibitor, in human plasma using high-performance liquid chromatography with post-column photochemical derivatization and fluorescence detection. , 1999, Journal of chromatography. B, Biomedical sciences and applications.

[23]  K. Oldhafer,et al.  A novel bioreactor design for in vitro reconstruction of in vivo liver characteristics. , 1995, Artificial organs.

[24]  K. Böker,et al.  3-D coculture of hepatic sinusoidal cells with primary hepatocytes-design of an organotypical model. , 1996, Experimental cell research.

[25]  R. Ings,et al.  Involvement of human UGT2B7 and 2B15 in rofecoxib metabolism. , 2003, Drug metabolism and disposition: the biological fate of chemicals.

[26]  Jilly F. Evans,et al.  Inhibition of cyclooxygenase-2 by rofecoxib attenuates the growth and metastatic potential of colorectal carcinoma in mice. , 2003, Cancer research.

[27]  N. A. Callejas,et al.  Absence of nuclear factor κB inhibition by NSAIDs in hepatocytes , 2002 .

[28]  O. Karlsen,et al.  UvA-DARE ( Digital Academic Repository ) In vitro evaluation of a novel bioreactor based on an integral oxygenator and a spirally wound nonwoven polyester matrix for hepatocyte culture as small aggregates , 2001 .

[29]  B. Clement,et al.  Survival, proliferation, and functions of porcine hepatocytes encapsulated in coated alginate beads: a step toward a reliable bioartificial liver. , 1997, Transplantation.

[30]  E. Drioli,et al.  The influence of polymeric membrane surface free energy on cell metabolic functions , 2001, Journal of materials science. Materials in medicine.