p63 is required beside p53 for PERP-mediated apoptosis in uveal melanoma
暂无分享,去创建一个
[1] Francesco Spagnolo,et al. Uveal melanoma. , 2012, Cancer treatment reviews.
[2] D. Spiller,et al. PERP expression stabilizes active p53 via modulation of p53-MDM2 interaction in uveal melanoma cells , 2011, Cell Death and Disease.
[3] D. Spiller,et al. P53 apoptosis mediator PERP: localization, function and caspase activation in uveal melanoma , 2009, Journal of cellular and molecular medicine.
[4] C. Eng,et al. Targeted therapy for uveal melanoma. , 2008, Cancer treatment reviews.
[5] N. Gruis,et al. Epigenetic regulation identifies RASEF as a tumor-suppressor gene in uveal melanoma. , 2008, Investigative ophthalmology & visual science.
[6] M. Lindstrom,et al. Resveratrol inhibits uveal melanoma tumor growth via early mitochondrial dysfunction. , 2008, Investigative ophthalmology & visual science.
[7] A. Yang,et al. p63 protects the female germ line during meiotic arrest , 2006, Nature.
[8] I. Grierson,et al. Expression of p53-induced apoptosis effector PERP in primary uveal melanomas: downregulation is associated with aggressive type. , 2006, Experimental eye research.
[9] D. Lohmann,et al. Establishment and characterization of two uveal melanoma cell lines derived from tumors with loss of one chromosome 3. , 2006, Experimental eye research.
[10] A. Balmain,et al. p63 and p73 do not contribute to p53-mediated lymphoma suppressor activity in vivo , 2005, Oncogene.
[11] Rebecca A. Ihrie,et al. A New Perp in the Lineup: Linking p63 and Desmosomal Adhesion , 2005, Cell cycle.
[12] Young Sun,et al. Functional analysis of the p53 pathway in response to ionizing radiation in uveal melanoma. , 2005, Investigative ophthalmology & visual science.
[13] A. Yang,et al. Tumor predisposition in mice mutant for p63 and p73: evidence for broader tumor suppressor functions for the p53 family. , 2005, Cancer cell.
[14] Rebecca A. Ihrie,et al. Perp Is a p63-Regulated Gene Essential for Epithelial Integrity , 2005, Cell.
[15] F. Alt,et al. p63 and p73 are not required for the development and p53-dependent apoptosis of T cells. , 2004, Cancer cell.
[16] T. Jacks,et al. Multiple response elements and differential p53 binding control Perp expression during apoptosis. , 2003, Molecular cancer research : MCR.
[17] T. Kivelä,et al. Very long-term prognosis of patients with malignant uveal melanoma. , 2003, Investigative ophthalmology & visual science.
[18] A. Yang,et al. A C-Terminal Inhibitory Domain Controls the Activity of p63 by an Intramolecular Mechanism , 2002, Molecular and Cellular Biology.
[19] K. Tsai,et al. p63 and p73 are required for p53-dependent apoptosis in response to DNA damage , 2002, Nature.
[20] N. Little,et al. Hdmx and Mdm2 can repress transcription activation by p53 but not by p63 , 2001, Oncogene.
[21] S. Berberich,et al. Regulation of p63 function by Mdm2 and MdmX. , 2001, DNA and cell biology.
[22] O. Larsson,et al. Concomitant loss of chromosome 3 and whole arm losses and gains of chromosome 1, 6, or 8 in metastasizing primary uveal melanoma. , 2001, Investigative ophthalmology & visual science.
[23] J. Harbour,et al. Deregulation of the Rb and p53 pathways in uveal melanoma. , 2000, American Journal of Pathology.
[24] J. Levine,et al. Surfing the p53 network , 2000, Nature.
[25] U. Weidle,et al. Identification of THW, a putative new tumor suppressor gene. , 2000, Anticancer research.
[26] S. Lowe,et al. PERP, an apoptosis-associated target of p53, is a novel member of the PMP-22/gas3 family. , 2000, Genes & development.
[27] Christopher P. Crum,et al. p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development , 1999, Nature.
[28] H. Vogel,et al. p63 is a p53 homologue required for limb and epidermal morphogenesis , 1999, Nature.
[29] A. Foss,et al. c-myc, p53, and Bcl-2 expression and clinical outcome in uveal melanoma , 1999, The British journal of ophthalmology.
[30] A. Yang,et al. p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities. , 1998, Molecular cell.
[31] V. Dixit,et al. Death receptors: signaling and modulation. , 1998, Science.
[32] W. Kaelin,et al. p73 is a human p53-related protein that can induce apoptosis , 1997, Nature.
[33] D. Albert. The ocular melanoma story. LIII Edward Jackson Memorial Lecture: Part II. , 1997, American journal of ophthalmology.
[34] M. Oren,et al. Mdm2 promotes the rapid degradation of p53 , 1997, Nature.
[35] I. McLean,et al. Uveal melanoma , 1997, Cancer.
[36] A. Levine. p53, the Cellular Gatekeeper for Growth and Division , 1997, Cell.
[37] A. Hagemeijer,et al. Establishment and characterization of primary and metastatic uveal melanoma cell lines , 1996, International journal of cancer.
[38] K. Kishore,et al. p53 gene and cell cycling in uveal melanoma. , 1996, American journal of ophthalmology.
[39] P T de Jong,et al. Immunohistochemical and prognostic analysis of apoptosis and proliferation in uveal melanoma. , 1995, The American journal of pathology.
[40] Bert Vogelstein,et al. Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53 , 1993, Nature.
[41] A. Levine,et al. The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation , 1992, Cell.
[42] W. Kaelin,et al. p73 is a simian [correction of human] p53-related protein that can induce apoptosis. , 1997, Nature.