Ultrasound-guided central venous catheter placement decreases complications and decreases placement attempts compared with the landmark technique in patients in a pediatric intensive care unit*

Objective:To determine whether ultrasound (US) increases successful central venous catheter (CVC) placement, decreases site attempts, and decreases CVC placement complications. Design and Setting:A prospective observational cohort study evaluating a transition by the Pediatric Critical Care Medicine service to US-guided CVC placement. Medical and surgical patients in a 21-bed quaternary multidisciplinary pediatric intensive care unit had CVCs placed by attendings, fellows, residents, and a nurse practitioner. Patients:Ninety-three patients were prospectively enrolled into the landmark (LM) group and 119 into the US group. Interventions:After collection of prospective LM data, training with US guidance was provided. CVCs were subsequently placed with US guidance. Measurements and Main Results:Operator information, disease process, emergent/routine, sites attempted, and complications were recorded. Procedure time was from initial skin puncture to guidewire placement. There was no difference overall in success rates (88.2% LM vs. 90.8% US, p = 0.54) or time to successful placement (median seconds 269 LM vs. 150 US, p = 0.14) between the two groups. Median number of attempts were fewer with US for all CVCs attempted (3 vs. 1, p < 0.001) as were attempts at >1 anatomical site (20.7% LM vs. 5.9% US, p = 0.001). Use of US was associated with fewer inadvertent artery punctures (8.5% vs. 19.4%, p = 0.03). Time to successful placement by residents was decreased with US (median 919 seconds vs. 405 seconds, p = 0.02). More internal jugular CVCs were placed during the US period than during the LM period (13.4% vs. 2.1%). Conclusions:US-guided CVC placement in children is associated with decreased number of anatomical sites attempted and decreased number of attempts to gain placement. Time to placement by residents was decreased with US, but not the time to placement by other operators. US guidance increased the use of internal jugular catheter placement and decreased artery punctures. US guidance did not improve success rates.

[1]  H. Baden [Central vein catheterization]. , 1971, Nordisk medicin.

[2]  Haim Bitterman,et al.  Central vein catheterization. Failure and complication rates by three percutaneous approaches. , 1986, Archives of internal medicine.

[3]  B. Fuhrman,et al.  Percutaneous central venous catheterization in a pediatric intensive care unit: a survival analysis of complications. , 1989, Critical care medicine.

[4]  T. Green,et al.  Percutaneous femoral venous catheterizations: A prospective study of complications , 1989 .

[5]  Bruno D. Fornage,et al.  Complications and failures of subclavian-vein catheterization. , 1994 .

[6]  P. Diggle,et al.  Analysis of Longitudinal Data , 2003 .

[7]  C. Eynon,et al.  Complications and failures of subclavian-vein catheterization. , 1995, The New England journal of medicine.

[8]  A G Randolph,et al.  Ultrasound guidance for placement of central venous catheters: a meta-analysis of the literature. , 1996, Critical care medicine.

[9]  Use of ultrasound imaging by emergency physicians. American College of Emergency Physicians. , 1997, Annals of emergency medicine.

[10]  S. Venkataraman,et al.  Femoral Vascular Catheterization in Critically Ill Infants and Children , 1997, Clinical pediatrics.

[11]  D. Saltzman,et al.  Complications and risks of central venous catheter placement in children. , 1998, Surgery.

[12]  P. Aadahl,et al.  [Ultrasound guidance for placement of central venous catheters]. , 1999, Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke.

[13]  F. Midgley,et al.  Ultrasound-guided internal jugular venous cannulation in infants: a prospective comparison with the traditional palpation method. , 1999, Anesthesiology.

[14]  F. Midgley,et al.  Comparison of three techniques for internal jugular vein cannulation in infants , 2000, Paediatric anaesthesia.

[15]  A. Serrano,et al.  Complications of central venous catheterization in critically ill children , 2001, Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies.

[16]  American College of Emergency Physicians. Use of ultrasound imaging by emergency physicians. , 2001, Annals of emergency medicine.

[17]  K. McDonald,et al.  Making health care safer: a critical analysis of patient safety practices. , 2001, Evidence report/technology assessment.

[18]  T. Mills,et al.  Ultrasound guidance versus the landmark technique for the placement of central venous catheters in the emergency department. , 2002, Academic emergency medicine : official journal of the Society for Academic Emergency Medicine.

[19]  S. Keenan,et al.  Use of ultrasound to place central lines. , 2002, Journal of critical care.

[20]  Daniel Hind,et al.  Ultrasonic locating devices for central venous cannulation: meta-analysis , 2003, BMJ : British Medical Journal.

[21]  D. Mason,et al.  NICE guidelines for central venous catheterization in children. Is the evidence base sufficient? , 2004, British journal of anaesthesia.

[22]  G. Leyvi,et al.  Utility of ultrasound‐guided central venous cannulation in pediatric surgical patients: a clinical series , 2005, Paediatric anaesthesia.

[23]  Theodore J. Gaeta,et al.  Randomized, controlled clinical trial of point-of-care limited ultrasonography assistance of central venous cannulation: The Third Sonography Outcomes Assessment Program (SOAP-3) Trial* , 2005, Critical care medicine.

[24]  Julie Leung,et al.  Real-time ultrasonographically-guided internal jugular vein catheterization in the emergency department increases success rates and reduces complications: a randomized, prospective study. , 2006, Annals of emergency medicine.

[25]  T. Milling,et al.  Randomized controlled trial of single-operator vs. two-operator ultrasound guidance for internal jugular central venous cannulation. , 2006, Academic emergency medicine : official journal of the Society for Academic Emergency Medicine.

[26]  T. Pirotte,et al.  Ultrasound-guided subclavian vein cannulation in infants and children: a novel approach. , 2007, British journal of anaesthesia.

[27]  T. Ohzeki,et al.  Ultrasound-Guided Versus Landmark-Guided Femoral Vein Access in Pediatric Cardiac Catheterization , 2008, Pediatric Cardiology.