Characterization of Implantable Antennas for Intracranial Pressure Monitoring: Reflection by and Transmission Through a Scalp Phantom

Characterization of implantable planar inverted-F antennas, designed for intracranial pressure (ICP) monitoring at 2.45 GHz, is presented. A setup, incorporating a scalp phantom emulating the implant environment and an absorbing chamber, was implemented for characterizing the antennas, in terms of their reflection coefficient (S 11), resonance frequency (fr), and transmission coefficient through the phantom (S 21) , and is reported for the first time. As a result of our observations that even a very slight change of the biocompatible (silicone) thickness can drastically change the characteristics of such antennas, several antenna prototypes with various silicone thicknesses were tested for a better understanding of the change in their performance with thickness. The main contributions of this paper rest in the evaluation of the antenna characteristics with respect to time, temperature, and far-field radiation, in an emulated biological environment. In this regard, the impact of the coating thickness on fr, drift of fr, S 11, and S 21 over time, and the effective radiated power (ERP) from the transmission (S 21) measurements were evaluated through careful measurements. A decrease in S 11 of 1.2-2.3 dB and an increase in S 21 of 2.2-2.4 dB, over a period of two days, were observed at 2.45 GHz. A decrease of 8-18 MHz for fr was also observed over the same period of time. This drift was due to the absorption of saline by the silicone, leading to a change in its effective dielectric property. An fr increase of approximately 14.5 MHz was also observed by raising the temperature from 20 degC to 37 degC, mainly because of the negative temperature coefficient of the phantom permittivity. Transmission measurements performed using both S 21 and the received power measurement (for an ICP device mimic) yielded a maximum ERP of approximately 2 mW per 1 W of power delivered to the antennas at 2.45 GHz.

[1]  R. Bansal,et al.  Antenna theory; analysis and design , 1984, Proceedings of the IEEE.

[2]  E. Topsakal,et al.  Design of a Dual-Band Implantable Antenna and Development of Skin Mimicking Gels for Continuous Glucose Monitoring , 2008, IEEE Transactions on Microwave Theory and Techniques.

[3]  Reinhold Ludwig,et al.  RF circuit design : theory and applications , 2000 .

[4]  C.M. Furse,et al.  Design of implantable microstrip antenna for communication with medical implants , 2004, IEEE Transactions on Microwave Theory and Techniques.

[5]  R. Bansal,et al.  The Near Field of an Insulated Dipole in a Dissipative Dielectric Medium (Short Paper) , 1986 .

[6]  Perambur S. Neelakanta,et al.  Handbook of Electromagnetic Materials: Monolithic and Composite Versions and their Applications , 1995 .

[7]  W. G. Scanlon,et al.  FDTD analysis of close-coupled 418 MHz radiating devices for human biotelemetry. , 1999, Physics in medicine and biology.

[8]  D. Misra,et al.  An experimental technique for in vivo permittivity measurement of materials at microwave frequencies , 1990 .

[9]  A.J. Johansson Performance of a radio link between a base station and a medical implant utilising the MICS standard , 2004, The 26th Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[10]  G. Lazzi,et al.  Investigation of a microwave data telemetry link for a retinal prosthesis , 2004, IEEE Transactions on Microwave Theory and Techniques.

[11]  K. T. Selvan Preliminary examination of a modified three-antenna gain-measurement method to simplify uncertainty estimation , 2003 .

[12]  A. Rosen,et al.  Wireless Intracranial Pressure Monitoring Through Scalp at Microwave Frequencies; Preliminary Phantom and Animal Study , 2006, 2006 IEEE MTT-S International Microwave Symposium Digest.

[13]  Issues in Wireless Intracranial Pressure Monitoring at Microwave Frequencies , 2007 .

[14]  Y. Rahmat-Samii,et al.  Implanted antennas inside a human body: simulations, designs, and characterizations , 2004, IEEE Transactions on Microwave Theory and Techniques.

[15]  J. Camart,et al.  Modeling of various kinds of applicators used for microwave hyperthermia based on the FDTD method , 1996 .

[16]  S. Verdeyme,et al.  Design Considerations for the Implanted Antennas , 2007, 2007 IEEE/MTT-S International Microwave Symposium.

[17]  A. Stogryn,et al.  Equations for Calculating the Dielectric Constant of Saline Water (Correspondence) , 1971 .

[18]  W.H. Kummer,et al.  Antenna measurements—1978 , 1978, Proceedings of the IEEE.

[19]  P. Bahr,et al.  Sampling: Theory and Applications , 2020, Applied and Numerical Harmonic Analysis.

[20]  U. Kawoos,et al.  In-Vitro and In-Vivo Trans-Scalp Evaluation of an Intracranial Pressure Implant at 2.4 GHz , 2008, IEEE Transactions on Microwave Theory and Techniques.

[21]  R. Olmi,et al.  Use of polyacrylamide as a tissue-equivalent material in the microwave range , 1988, IEEE Transactions on Biomedical Engineering.

[22]  L. Roy,et al.  Monopole antennas for microwave catheter ablation , 1996 .

[23]  J. Strohbehn,et al.  The Electromagnetic Field of an Insulated Antenna in a Conducting Or Dielectric Medium , 1983 .