Segmental Mandibulectomy and Immediate Free Fibula Osteoseptocutaneous Flap Reconstruction with Endosteal Implants: An Ideal Treatment Method for Mandibular Ameloblastoma

Thirteen patients with large ameloblastomas of the mandible underwent segmental mandibulectomy and immediate reconstruction, with simultaneous placement of osseointegrated implants. All patients received palatal mucosal grafts around the dental implants 6 to 10 months after surgical treatment and received implant-supported prostheses another 1 to 2 months later. There were five female and eight male patients, with a mean age of 32 years (range, 17 to 50 years). The mean length of the mandibular defect was 8.8 cm (range, 5 to 13 cm). All free fibula flap procedures were successful, with no reexplorations or partial flap losses. There was no clinical or radiographic evidence of failure during the osseointegration process for any implant. With functional occlusal loading, the marginal bone loss around the implants was less than 1.5 mm in a mean follow-up period of 40 months (range, 18 to 70 months). There were no recurrences during that time. The technique described allows improved access to the bone at the time of reconstruction, immediate assessment of alveolar ridge relationships, and accurate fixation of the implant-fibula construct. The advantages of this procedure include a reduced risk of recurrence with segmental resection, reliable mandibular reconstruction, and reduction of the number of surgical procedures, allowing full oral rehabilitation in a shorter time. It is concluded that segmental mandibulectomy and immediate vascularized fibula osteoseptocutaneous flap reconstruction, with simultaneous placement of osseointegrated implants, represent an ideal treatment method for large ameloblastomas of the mandible.

[1]  J. Schweiger Titanium implants in irradiated dog mandibles. , 1989, The Journal of prosthetic dentistry.

[2]  L. Ellies,et al.  The prevalence of altered sensation associated with implant surgery. , 1993, The International journal of oral & maxillofacial implants.

[3]  T. Albrektsson,et al.  Integration of Titanium Implants in Irradiated Bone Histologic and Clinical Study , 1988, The Annals of otology, rhinology, and laryngology.

[4]  N. Jones,et al.  Reliability of the Fibular Osteocutaneous Flap for Mandibular Reconstruction: Anatomical and Surgical Confirmation , 1996, Plastic and reconstructive surgery.

[5]  P. Slootweg,et al.  The growth characteristics of multilocular ameloblastomas. A histological investigation with some inferences with regard to operative procedures. , 1985, Journal of maxillofacial surgery.

[6]  N J Mankovich,et al.  Stereolithographic models for surgical planning: preliminary report. , 1992, Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons.

[7]  G. W. Willis,et al.  Ameloblastoma of maxilla and mandible , 1974 .

[8]  J. Hayter,et al.  Oral rehabilitation with endosteal implants and free flaps. , 1996, International journal of oral and maxillofacial surgery.

[9]  I M Zlotolow,et al.  Osseointegrated implants and functional prosthetic rehabilitation in microvascular fibula free flap reconstructed mandibles. , 1992, American journal of surgery.

[10]  R. Ewers,et al.  Solitary plasmocytoma of the mandible--a combined approach for treatment and reconstruction. , 1997, International journal of oral and maxillofacial surgery.

[11]  M. Mommaerts,et al.  Late loco-regional recurrences after radical resection for mandibular ameloblastoma. , 1988, International journal of oral and maxillofacial surgery.

[12]  D. Gardner A pathologist's approach to the treatment of ameloblastoma. , 1984, Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons.

[13]  M. Pogrel,et al.  Management of mandibular ameloblastoma: the clinical basis for a treatment algorithm. , 1999, Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons.

[14]  F. Wei,et al.  Fibula Osteoseptocutaneous Flap for Reconstruction of Composite Mandibular Defects , 1994, Plastic and reconstructive surgery.

[15]  D. E. Smith,et al.  Criteria for success of osseointegrated endosseous implants. , 1989, The Journal of prosthetic dentistry.

[16]  F. Wei,et al.  Use of waxing screws for accurate primary placement of endosteal implants in the vascularized fibular bone-reconstructed mandible. , 2003, Plastic and reconstructive surgery.

[17]  D. Gardner,et al.  The treatment of ameloblastoma based on pathologic and anatomic principles , 1980, Cancer.

[18]  M Wichmann,et al.  Postoperative Function after Implant Insertion in Vascularized Bone Grafts in Maxilla and Mandible , 1996, Plastic and reconstructive surgery.

[19]  E. Roumanas,et al.  Reconstructed Mandibular Defects: Fibula Free Flaps and Osseointegrated Implants , 1997, Plastic and reconstructive surgery.

[20]  Ellies Lg,et al.  The prevalence of altered sensation associated with implant surgery. , 1993 .

[21]  A. Weiland,et al.  The Effect of Prolonged Ischemia Time on Osteocyte and Osteoblast Survival in Composite Bone Grafts Revascularized by Microvascular Anastomoses , 1982, Plastic and reconstructive surgery.

[22]  D. Hidalgo Titanium Miniplate Fixation in Free Flap Mandible Reconstruction , 1989, Annals of plastic surgery.

[23]  D. Buchbinder,et al.  Resistance to osteoradionecrosis in neovascularized bone , 1993, The Laryngoscope.

[24]  D. Hidalgo Fibula free flap: a new method of mandible reconstruction. , 1989, Plastic and reconstructive surgery.

[25]  E. Santamaria,et al.  Primary Insertion of Osseointegrated Dental Implants into Fibula Osteoseptocutaneous Free Flap for Mandible Reconstruction , 1998, Plastic and reconstructive surgery.

[26]  S. Feinberg,et al.  Surgical management of ameloblastoma. Current status of the literature. , 1996, Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics.

[27]  M W Bidez,et al.  Force transfer in implant dentistry: basic concepts and principles. , 1992, The Journal of oral implantology.

[28]  T. Wu,et al.  Ameloblastoma of the mandible treated by resection, preservation of the inferior alveolar nerve, and bone grafting. , 1984, Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons.

[29]  P. Stoll,et al.  Use of the "double barrel" free vascularized fibula in mandibular reconstruction. , 1998, Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons.

[30]  P. Branemark,et al.  Osseointegrated implants in irradiated bone: a case-controlled study using adjunctive hyperbaric oxygen therapy. , 1999, Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons.