Ultrafast computed tomography-detected coronary calcium reflects the angiographic extent of coronary arterial atherosclerosis.

Abstract This study demonstrates the potential of ultrafast CT quantification of coronary calcium to reflect the extent of atherosclerosis measured by coronary angiography. The findings are concordant with pathology studies that have also shown a close relation between the extent of coronary calcium and the extent of atherosclerosis.6 The usefulness of this technique in finding a population of asymptomatic subjects in whom aggressive risk factor modification would be cost-effective should be explored.

[1]  J. Strong,et al.  Coronary Calcification: Relationship to Clinically Significant Coronary Lesions and Race, Sex, and Topographic Distribution , 1965, Circulation.

[2]  D. Hackel,et al.  Comparison of angiographic and postmortem findings in patients with coronary artery disease. , 1975, The American journal of cardiology.

[3]  Yves Taeymans,et al.  Clinical and Angiographic Factors Associated With Coronary Artery Disease Progression of Coronary Artery Disease , 1984 .

[4]  C M Grondin,et al.  Discrepancies Between Cineangiographic and Postmortem Findings in Patients with Coronary Artery Disease and Recent Myocardial Revascularization , 1974, Circulation.

[5]  J. Murray,et al.  Variability in the Analysis of Coronary Arteriograms , 1977, Circulation.

[6]  P. Sheedy,et al.  Detection of heart calcification with electron beam CT: interobserver and intraobserver reliability for scoring quantification. , 1994, Radiology.

[7]  W. Roberts,et al.  Quantitation of coronary arterial narrowing at necropsy in sudden coronary death: analysis of 31 patients and comparison with 25 control subjects. , 1979, The American journal of cardiology.

[8]  J F Breen,et al.  Coronary artery calcification detected with ultrafast CT as an indication of coronary artery disease. , 1992, Radiology.

[9]  R. Schwartz,et al.  Fluoroscopic coronary artery calcification and associated coronary disease in asymptomatic young men. , 1992, Journal of the American College of Cardiology.

[10]  R. Frye,et al.  A reporting system on patients evaluated for coronary artery disease. Report of the Ad Hoc Committee for Grading of Coronary Artery Disease, Council on Cardiovascular Surgery, American Heart Association. , 1975, Circulation.

[11]  A. Leaf.  Management of hypercholesterolemia. Are preventive interventions advisable? , 1989, The New England journal of medicine.

[12]  S. Grundy.  Cholesterol and coronary heart disease. Future directions. , 1990, JAMA.

[13]  W. Edwards,et al.  Noninvasive definition of anatomic coronary artery disease by ultrafast computed tomographic scanning: a quantitative pathologic comparison study. , 1992, Journal of the American College of Cardiology.

[14]  W. Roberts,et al.  Coronary artery narrowing in coronary heart disease: comparison of cineangiographic and necropsy findings. , 1979, Annals of internal medicine.

[15]  Cross sectional coronary artery stenosis. , 1977, Catheterization and cardiovascular diagnosis.

[16]  R. Detrano,et al.  Quantification of coronary artery calcium using ultrafast computed tomography. , 1990, Journal of the American College of Cardiology.

[17]  L. Solberg,et al.  Atherosclerosis in persons with coronary heart disease. , 1968, Laboratory investigation; a journal of technical methods and pathology.

[18]  Steven E. Nissen,et al.  Intravascular Ultrasound Assessment of Lumen Size and Wall Morphology in Normal Subjects and Patients With Coronary Artery Disease , 1991, Circulation.

[19]  M J Davies,et al.  Potential errors in the estimation of coronary arterial stenosis from clinical arteriography with reference to the shape of the coronary arterial lumen. , 1986, British heart journal.